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Sensitivity in Biological News

Colon cancer screening technique shows continued promise in new study

... University researchers has a high enough sensitivity that it could potentially be as or more ... showed that for advanced polyps, the test had a sensitivity of 100 percent, which means that 100 percent of ... healthy samples from diseased samples. While the sensitivity and specificity of tests may vary based on the ...

Does mom know when enough is enough?

... that solid food was introduced, and the mothers' sensitivity to the infants' signals at 3 months were ... infant length gain from 3 to 6 months, maternal sensitivity to infant signals at 6 months, and the estimated ... weight gain from 6 to 12 months, and maternal sensitivity to the infants' signals reached predictive ...

Studies point to novel target for treating arrhythmias

... mutations associated with HCM increase the sensitivity of the troponins to calcium they bind calcium ... contractions. Increased myofilament calcium sensitivity has also been found in acquired heart diseases, ... proposed that increased myofilament calcium sensitivity contributes to arrhythmia susceptibility. The ...

January-February GSA Bulletin media highlights

... fossils in Ireland that suggests high ice-sheet sensitivity to small climate changes; formation of Valles ... of western Ireland and implications for sensitivity of the Irish Ice Sheet to climate change ... the Killard Point stadial, suggesting a high sensitivity of the ice sheet to small changes in climate. ...

Honeybees succumb to cocaine's allure

... However, when Paul Helliwell tested the bees' sensitivity to sugar solutions, the drugged bees responded ... sensitivity. But was it only increasing their sensitivity to sugar, or increasing their response to all ... insects pollen to see if cocaine increased their sensitivity to other floral rewards and found that the ...

A BBVA Foundation project comes up with a system enabling detection of cetacean hearing loss

... date, the only way to measure cetaceans' hearing sensitivity was to remove them to a laboratory. However this ... signals, as well as measuring cetaceans' hearing sensitivity to certain frequencies by analyzing the evoked ... images. At the same time, by measuring the ear's sensitivity to certain frequencies we can gauge the physical ...

Meeting to highlight health impacts of smell and taste

... to accurately measure normal ranges of taste sensitivity by gender and age, scientists need a ... for biological factors that raise or lower sensitivity to sweet tastes and might stoke desire for ... peptide-1 (GLP-1) that appears to modulate sensitivity to sweet tastes. Scientists already knew that ...

Too hot to handle! Scientists identify heat sensing regulator

... Hopkins are a step closer to understanding pain sensitivity - specifically why its variable instead of ... Pirt appears in the May 2 issue of Cell. Pain sensitivity increases during inflammation or injury and we ... molecules are involved in pain sensation when sensitivity is elevated, says Xinzhong Dong, Ph.D., an ...

Tips from the Journals of the American Society for Microbiology

... respiratory viruses, slow response time and low sensitivity are suboptimal for routine detection practices. ... as the cell culture, or gold standard, in both sensitivity and specificity. Only test results for rhinovirus ... ICA, the RespiFinder showed a specificity and sensitivity of approximately 80%. The RespiFinder assay ...

Plants can be used to study how and why people respond differently to drugs

... of a family of proteins that also affect drug sensitivity in humans. Similar biochemical processes are affecting drug sensitivity in both plants and animals, said Cutler, who ... to that seen in humans, where altered drug sensitivity can occur because of defective or atypical ...

Soccer burns more fat than jogging

... percentage of fat, blood pressure, insulin sensitivity and balance. Surprising results - 2-3 weekly ... improvements in blood pressure, insulin sensitivity and balance. The sports scientist believes ... of muscles, cholesterol, blood pressure, insulin sensitivity and balance. ...

Building memories with actin

... is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 ... of LTP, and the Rac-PAK pathway solidifies them so that heightened synapse sensitivity can persist. The researchers hypothesize that one pathway encodes ...

Investigating the development of mechanosensitivity

... At the same time they were able to show that neurons develop their sensitivity to touch and pain during different developmental phases but always ... signals to the brain. Very little, however, is known about how stimulus sensitivity actually emerges. Using the patch-clamp technique in isolated cells of ...

MIT reels in RNA surprise with microbial ocean catch

... or pressure and modify their protein expression accordingly. But that sensitivity creates a quandary for the scientists who study them. Sort of like the ... observer causes the microbes to change their protein expression. That same sensitivity makes some of these creatures exceedingly difficult to grow in lab ...

Sugar, spice and puppy dog tails: Developing sex-typed personality traits and interests

... feminine, expressive traits didn't change over time. In contrast, boys' sensitivity and warmth declined substantially across middle childhood but increased in ... so that by about age 19, boys reported about the same levels of sensitivity and warmth as girls. For stereotypically masculine traits such as ...

New drug shows promise in treating drug-resistant prostate cancer

... appear to work well even in prostate cells that have a heightened sensitivity to hormones; that heightened sensitivity makes prostate cancer cells resistant to existing anti-androgen therapies. ...

New medications show promise in treating drug-resistant prostate cancer

... RD162 appear to work well even in prostate cells that have a heightened sensitivity to hormones. That heightened sensitivity makes prostate cancer cells resistant to existing antiandrogen therapies. ...

CSHL team develops mouse models of leukemia that predict response to chemotherapy

... will respond to therapy and help to identify genes promoting resistance or sensitivity to any cancer drug. The mouse models, the CSHL team notes, also serve as ... and getting a correct read-out in terms of outcome prediction." sensitivity vs. resistance to chemotherapy Experiments in which the team treated ...

Symposium to look at genetic basis of exercise

... gene, played an important role in determining an individual's insulin sensitivity and glucose disposal ability in response to exercise. This gene, like ... variants. Individuals with one variant of this gene improved their insulin sensitivity and glucose disposal ability with exercise while people with another ...

New method for detecting explosives

... realized they could detect explosives selectively and with extremely high sensitivity by building sensors that probed the thermal signatures of chemical vapors. ... (a picogram is a trillionth of a gram). They are now improving the sensitivity and making a prototype device, which they expect to be ready for field ...

Musicians have biological advantage in identifying emotion in sound

... "Previous research has indicated that musicians demonstrate greater sensitivity to the nuances of emotion in speech," says Ashley, who explores the link ... through earphones, a 250-millisecond fragment of a distressed baby's cry. sensitivity to the sound, and in particular to the more complicated part of the sound ...

AGU journal highlights -- Dec. 31, 2008

... or tornado-like circulations and were therefore not able to study the sensitivity of tornadogenesis to microphysics. Snook and Xue have now conducted ... impact on regional precipitation over western Africa, mechanisms and sensitivity to absorption properties Authors: Fabien Solmon, Marc Mallet, and ...

Bright lights, not-so-big pupils

... Hopkins. "We want to understand some fundamental information, like their sensitivity to light and their communication to the brain." Using mice, the team first tested the light sensitivity of these cells by flashing light at the cells and recording the electrical ...

Sensitive laser instrument could aid search for life on Mars

... biomolecules at concentrations as low as 3 parts per trillion. High sensitivity is crucial for NASA's search for life on Mars, says INL scientist Jill ... detected a signature for the biomolecules. The team also measured the sensitivity of its instrument for the first time. By testing more and more dilute ...

Sensitive nanowire disease detectors made by Yale scientists

... from a general immune stimulation of other cells. Describing the sensitivity of the system, senior author Tarek Fahmy , Yale assistant professor of ... hear the few above the many." According to the authors, this level of sensitivity and specificity is unprecedented in a system that uses no dyes or ...

Swiss Institute of Bioinformatics celebrates 10th birthday by presenting major gifts to human health

... (May 2008), which allows scientists to check human cell lines for their sensitivity to thousands of drugs. Major breakthrough in biological science first ... a computational tool which may eventually allow scientists to predict the sensitivity of different patients to a range of drugs. "We call it the Ping-Pong ...

MicroRNA implicated as molecular factor in alcohol tolerance

... noted NIAAA Director Ting-Kai Li, MD. Tolerance is the decrease in sensitivity to alcohol that develops with repeated exposures to alcohol over time. ... In both regions, alcohol tolerance was manifested as decreased alcohol sensitivity and reduced BK channel density. Previous studies have also shown that ...

Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds

... esophageal cancer and are higher in patients with metastatic disease, the sensitivity and specificity of these markers in the diagnosis of recurrent cancer has ... and prediction of recurrence of this disease." The study analyzed the sensitivity and specificity of plasma DNA as a preoperative marker of metastasized ...

Fluorescent nano-barcodes could revolutionize diagnostics

... has developed fluorescent barcodes called nanostrings, offers greater sensitivity and accuracy than current detection methods. The research has been ... will be new nano-barcodes that will further reduce the cost and improve sensitivity and usability. ...

How can we measure the emotional states of animals?

... sensitive to losses. The researchers wanted to know whether animals' sensitivity to reward loss might also be related to their emotional state. Many ... Biology at Bristol University consider the research indicates that sensitivity to reward reduction may be a valuable new indicator of animal emotion and ...

Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines

... unnecessary follow-up tests. SCORED demonstrates 88 to 95 percent sensitivity (how well the test correctly identifies people who have the disease) and a ... people who do not have the disease). In comparison, KEEP demonstrates a sensitivity of 86 to 92 percent and a specificity of 24 to 35 percent. Predictive ...

Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity

... that moderate exposure to alcohol and stress during pregnancy can lead to sensitivity to touch in the monkeys babies. In human children, sensitivity to touch is one of a number of characteristics of the approximately 5 ...

Rice scientists make breakthrough in single-molecule sensing

... can mass-produce these in known locations, and they have single-molecule sensitivity at room temperature in open air," said study co-author Douglas Natelson, ... Raman spectroscopy (SERS). "Our latest results confirm that we have the sensitivity required to measure single molecules," said LANP Director Naomi Halas, the ...

Human hormone blocker found to help prevent obesity and diabetes: study

... a key role in obesity-related diseases). Glucose tolerance and insulin sensitivity tests were performed at the end of the study period. The metabolic ... of plasma glucose and gyrated hemoglobin, leading to impaired insulin sensitivity and glucose intolerance by 10 days. Fat (adipose) tissue deposits were ...

SLIM Search Launches Academic Pricing Program

... CEO of SLIM Search, Ltd. "SLIM Search provides more speed, flexibility and sensitivity for the academic researcher performing biotechnology, molecular ... is used to find it. When the chunking conditions are set the same, the sensitivity will be identical between SLIM Search and any method it is compared with, ...

Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design

... protein biomarkers in a variety of biological samples with extreme sensitivity and accuracy. Singulex is currently conducting several pilot studies ... their vital immunoassays, adding as much as 1-3 logs of improvement in sensitivity and providing less than 20% coefficient of variability. ETAP includes the ...

Woods Hole Research Center debuts new image mosaic that will strengthen global forest monitoring

... data are acquired several times per year for years to come. With a strong sensitivity of the ALOS radar imaging sensor to vegetation structure, this marks a new ... on producing an accurate forest/nonforest map. In the forested areas, the sensitivity of the PALSAR data to differences in aboveground biomass is also being ...

Lush or lightweight?

... scientists found that a number of fruit fly genes undergo changes when sensitivity to alcohol changes. A number of these genes, the researchers report, ... to it, the NC State study first artificially selected flies for alcohol sensitivity creating the lushes and the lightweights and then, in a "whole-genome" ...

UCSB researchers discover the dawn of animal vision

... evolving animals like sponges, we can put a date on the evolution of light sensitivity in animals, said David C. Plachetzki, first author and a graduate student ... Hydras are predators, and the authors speculate that they use light sensitivity in order to find prey. Hydra use opsin proteins all over their bodies, but ...

New field-deployable biosensor detects avian influenza virus in minutes instead of days

... of the viral particle. For this study, the researchers evaluated the sensitivity of three unique antibodies to detect avian influenza virus. The sensor ... capture immunoassays can provide rapid test results, but suffer from low sensitivity and high cost. Beyond the waveguide sensor, the only additional ...
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