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Seizures in Biological News

Rutgers research tackles childhood epilepsy

... in organ transplants, suppressed epileptic seizures in the mice. Epilepsy is the third most common ... age 15. More than 90,000 of them have severe seizures that cannot be adequately treated. The children ... problems due to recurrent and uncontrolled seizures and the combined effects of heavy medication. ...

Camphor-containing products may cause seizures in children

... may be a common and underappreciated cause of seizures in young children, according to a new study by ... report on three cases of camphor-associated seizures in children seen in the emergency department of a ... rubbed on her skin hourly for 10 hours before her seizures began. (Interestingly, this girl and two of her ...

Drug prevents seizure progression in model of epilepsy

... a new anticonvulsant compound that eliminates seizures in a model of epilepsy," said Alison Barth, ... diagnosed with epilepsy after having two or more seizures that have no other apparent cause. In prior ... but Barth and colleagues demonstrated that seizures themselves could lead to the same alterations in ...

International team discovers gene associated with epilepsy

... in the brain signal abnormally and cause repeated seizures that can include strange sensations, severe muscle spasms and loss of consciousness. The seizures may not have lasting effects but can affect ... as limiting a person's ability to drive. Most seizures do not cause brain damage but some types of ...

Drops in blood oxygen levels may be key to sudden death in some epilepsy patients

... Seyal and his colleagues examined records of 300 seizures in 57 epilepsy patients with chronic, recurrent, ... They compared patients with severe convulsive seizures to those with milder symptoms like transient ... smacking and head turning. One-third of all seizures were associated with drops in blood-oxygen levels ...

Study identifies brain pathway that shuts down seizures

... Subsequent studies in the 1950s found that seizures themselves reduce brain pH. However, it was the ... the ASIC1a gene have more severe and longer seizures than mice with the gene. In addition, chemically ... ASIC1a increases the severity and duration of seizures in mice with the gene. Conversely, increasing the ...

Early treatment stops epilepsy in its tracks

... medication ethosuximide before the onset of seizures led to a marked suppression of seizures both later in life and months after treatment ... neurons of the brain and reduced the number of seizures in treated animals. These findings prove ...

Scientists track impact of DNA damage in the developing brain

... throughout the nervous system. Some mice in the study eventually develop seizures and difficulty walking. Peter J. McKinnon, Ph.D., a member of St. Jude ... temporal lobe epilepsy. In this study, the loss of Xrcc1 also resulted in seizures in mice. ...

Researchers discover that gene switches on during development of epilepsy

... thalamus is connected to the hippocampus and is involved in the spread of seizures throughout the brain. "Certain kinds of channels are normal and ... becomes dominated by the new copies of this channel. It helps explain how seizures can develop and spread." The particular gene that codes for the ...

Peering inside the skull of a mouse to solve meningitis mystery

... in La Jolla, Calif., have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous ... Mice infected with LCMV suffer fatal seizures. It was known that these seizures are not caused by the virus itself, but by the immune system's response to ...

Domoic acid from toxic algal blooms may cause seizures in California sea lions

... of the online journal Marine Drugs , state that an increase of epileptic seizures and behavioral abnormalities in California sea lions can result from ... phenomenon, known as "fetal basis to adult disease," is expressed through seizures and abnormal behavioral changes. "This represents a significant break ...

NIH stimulus funding supports Emory biomedical scientists

... to block such growth signals could generate new tools to fight cancer. New treatments for epilepsy: Some epilepsy patients cannot control their seizures with drugs. Animal research shows that shutting off a gene called SCN8A can lower susceptibility to seizures. Scientists plan to test a ...

Reading the brain without poking it

... of the much larger electrodes used for electrocorticography, or ECoG, developed a half century ago. For patients with severe epileptic seizures that are not controlled by medication, surgeons remove part of the skull or cranium and place a silicone mat containing ECoG electrodes over the ...

UF makes gene therapy advance in severe genetic disorder

... that point, the kids can do fine. If it is not diagnosed, then the kids get exposed to recurrent low sugars, and they will end up with brain damage, seizures or they will die." UF researcher Cathryn Mah, Ph.D., a member of the Powell Gene Therapy Center and UF Genetics Institute, will present the ...

Bull's-eye electrode helps interpret thoughts, deliver stimulus to aid paralyzed, epileptic patients

... the electrode can be used in a therapeutic manner to administer an electrical stimulus to a precise location in the brain to control epileptic seizures or treat other neurological disorders. He has been awarded a $397,000 grant from the National Institutes of Health to verify his earlier experiments ...

UW-Madison study reveals new options for people with PKU

... trials, the researchers discovered they already had a long list of eager volunteers, including Matt Cortright of Wausau, Wisconsin, who developed seizures and other problems after abandoning the amino acid formula for a few years during early adulthood. "The main reason I helped out with this study ...

Gorilla gets MRI at Bronx Zoo

... concluded that Fubo's condition is not treatable with surgery, so they will continue to treat the gorilla with medication in an effort to control his seizures and other clinical signs. "Thanks to the generosity of The Brain Tumor Foundation, we were able to perform an MRI of Fubo's brain and this gave us ...

Statins may treat blood vessel disorder that can lead to fatal strokes

... trial of statins. CCM is a disorder in which blood vessels in the brain become dilated and weakened, and leak blood, causing strokes, headaches, seizures or other problems. Diagnosing CCM can be problematic. Some people are diagnosed after experiencing symptoms and undergoing an MRI; others find out ...

Miscarriage and infertility treatment increase pre-eclampsia risk

... can be unaffected by the condition, but in serious cases, pre-eclampsia can be life-threatening for mother and baby, with organ failure and danger of seizures among mothers. The child risks poor growth and development due to insufficient placenta function. The only treatment is delivery of baby and ...

Epilepsy drug shows potential for Alzheimer's treatment

... this is likely to double within a generation unless new treatments are found. Sodium valproate has been used for many years to suppress epileptic seizures and the many sufferers of epilepsy have been taking the drug for decades with few side effects. The development of Alzheimer's is widely believed ...

Alcohol: A life sentence

... is delayed. Many of them are poor learners or display conspicuous behavior. Psychiatric and neurological disorders such as depression and epileptic seizures occur with increased frequency. ...

Common treatment to delay labor decreases preterm infants' risk for cerebral palsy

... Americans between the ages of 3 and 13, making it a leading cause of chronic childhood disability. Magnesium sulfate is given routinely to prevent seizures in women with preeclampsia and to stop preterm labor. Previous research suggested that fetal exposure to magnesium sulfate before preterm birth might ...

UC Davis researchers define characteristics, treatment options for XXYY syndrome

... as congenital heart defects and mitral valve prolapse, 87.6 percent had dental problems such as severe dental caries and malocclusion, 15 percent had seizures and 59.8 percent had asthma or other respiratory issues. Intention tremor became more common with age and was present in 71 percent of study ...

Model for angelman syndrome developed by University of Texas at Austin biologists

... up and interfere with brain functions," Fischer says. The symptoms of Angelman syndrome in humans include severe mental retardation, epileptic seizures and sleep disturbances. The work Wu, Fischer and their collaborators have done over the last six years has involved engineering fruit flies with ...

Ivory poaching at critical levels: Elephants on path to extinction by 2020?

... Hong Kong had been sent from Cameroon, but DNA forensics showed it came from an area centered on Gabon. Evidence gathered from recent major ivory seizures shows conclusively that the ivory is not coming from a broad geographic area but rather that hunters are targeting specific herds. With such ...

Researcher helping to pioneer medical therapy for Fragile X Syndrome presents latest findings

... a number of discussions at the conference including a plenary session on promising new treatments and clinical sessions on stem cell research, seizures and psychopharmacology. In addition, she will be presenting research on the use of lithium to target the underlying defect in Fragile X Syndrome. ....

Brain study may lead to improved epilepsy treatments

... Germany, is available online and will appear in the May 2008, issue of Molecular Pharmacology. Our work identifies the mechanism by which seizures increase production of a drug transport protein in the blood brain barrier, known as P-glycoprotein, and suggests new therapeutic targets that could ...

Tips from the Journals of the American Society for Microbiology

... cerebrospinal fluid and some of the symptoms exhibited by the patients include fever, altered mental status, and abnormal CSF profile, as well as seizures in those ages 3 and under. Results showed that 26 specimens from 24 patients were positive for HHV-6, of which 20 were identified as the HHV-6B ...

New brain cells listen before they talk

... if we want to use stem cells to replace neurons lost to injury or disease, we must ensure that they do not fire inappropriately, which could cause seizures or cognitive dysfunction. ...

The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases

... that causes irreversible neurodegeneration in adolescents and for which no treatment is available. Lafora disease generally presents as epileptic seizures between 10 to 17 years of age and later on as myoclonus (involuntary twitching of the arms and legs). Its evolution is marked by progressive ...

MIT: blood may help us think

... and that insight suggests entirely new treatments. For example, in epilepsy people often have abnormal blood vessels in the brain region where the seizures occur, and the hypothesis suggests this abnormal flow may induce epileptic onset. If so, drugs that affect blood flow may provide an alternative to ...

Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures

... temperature can have a down side: in about one in 25 infants or small children, high fever can trigger fever-induced (febrile) seizures. While the seizures themselves are generally harmless, a prolonged fever resulting from infection or heatstroke of over 108˚F (42˚C) can eventually lead to ...

Gene therapy inhibits epilepsy in animals

... significantly reduce the development of epileptic seizures in rats. "We have shown that there is a window ... of brain cells that characterizes a seizure. seizures are thought to occur, at least in part, because ... an area that is critical to generating seizures in temporal lobe epilepsy, the most common type ...

How brain injury leads to seizures, memory problems

... turn, is thought to be an underlying reason for seizures and memory defects experienced by people who have ... Dr. Cohen, "neurons become more excitable, and seizures can occur." In addition to its role in ... the ability to learn new things." Epileptic seizures and impaired memory are two of the disabilities ...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

... The brain's septum helps prevent epileptic seizures by inducing rhythmical electrical activity in the ... epileptic rats, they could reduce epileptic seizures by 86-97 percent. The study "Septo-hippocampal ... to produce status epilepticus, in which sustained seizures occur. The rats received diazepam three hours ...

Molecular mechanism may explain how fevers spark seizures

... new approaches for preventing recurrent febrile seizures in vulnerable children. Febrile seizures affect as many as one in 15 children worldwide, ... through the years: do you treat febrile seizures or not?" Macdonald said. Several studies have ...

Decoy pill saves brain cells

... then injected the mice with kainic acid, a chemical known to cause seizures and neuron death. While seizures still occurred, as in control mice, no brain lesions were observed in the ...

New neurons could act to alleviate epilepsy

... to exercise by running on a wheel with those in rats in which epileptic seizures were induced by electrical brain stimulation. Specifically, the ... the hippocampus. This structure is known to be a "gate" for propagation of seizures in the hippocampus, a center for learning and memory. The ...

Gene variations explain drug dose required to control seizures

... error and improve quality of life for patients," he added. Epilepsy and seizures affect 2.5 million Americans of all ages, with approximately 181,000 new ... said. "For someone at the higher end, it can take months to get their seizures under control. This study uncovers factors that might determine, in ...
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