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Rhesus in Biological News

Cutting-edge amfAR grants fight HIV/AIDS in the lab and on the phone

... UT $125,000 Identifying cellular cofactors of rhesus monkey TRIM5-alpha: While the evolutionary ... differences in the protein TRIM5-alpha between rhesus monkeys and humans mean that the rhesus form of the protein can inhibit HIV infection ...

Tips from the Journals of the American Society for Microbiology

... were inoculated with murine rotaviruses and the rhesus monkey rotavirus. Following infection results ... agent. Following intramuscular vaccination, rhesus macaques showed high antibody levels that ... vector provides significant protection in rhesus monkeys against all four serotypes of dengue ...

Humans and monkeys share Machiavellian intelligence

... act like monkeys, or more specifically, like rhesus macaques, a type of monkey that shares with ... at the University of Chicago. After humans, rhesus macaques are one of the most successful primate ... in his new book Macachiavellian Intelligence: How rhesus Macaques and Humans Have Conquered the World. ...

Monkeys use 'baby talk' to interact with infants

... Female rhesus monkeys use special vocalizations while ... researchers studied a group of free-ranging rhesus macaques, which live on an island off the coast ... of Grunt and Girney Vocalizations in Free-Ranging rhesus Macaques published in the current issue of the ...

Why some primates, but not humans, can live with immunodeficiency viruses and not progress to AIDS

... progressing to AIDS-like illness, unlike other primate species, including rhesus macaques and humans, that succumb to disease. Following the ... lower extent during SIV infection than are the immune systems of rhesus macaques, and that this difference may explain why SIV and HIV infection ...

Simian foamy virus found in several people living and working with monkeys in Asia

... India, for example, researchers estimate that more than a quarter-million rhesus macaques, or about 86 percent of the wild population, live in urban areas ... of habitat loss. Unlike the great apes, such as chimpanzees or gorillas, rhesus macaques and other species of monkeys are very adaptable to new habitats. ...

Yerkes researchers identify language feature unique to human brain

... compared the size and trajectory of the arcuate fasciculus in humans, rhesus macaques and chimpanzees. According to Rilling, "The human arcuate fasiculus differed from that of the rhesus macaques and chimpanzees in having a much larger and more widespread ...

Oosight microscope enables embryonic stem cell breakthrough

... the meiotic spindle (and the attached genetic material) from 304 female rhesus monkey eggs. This is the first step in therapeutic cloning, called ... they inserted the genetic material from the skin cells of an adult male rhesus monkey into the eggs and allowed them to grow to the blastocyst stage. ...

Primate sperm competition: speed matters

... reported that sperm cells from the more promiscuous chimpanzee and rhesus macaque species swim much faster and with much greater force than those of ... is polygamous and that is consistent with our measurements of chimp and rhesus macaque sperm, said Nascimento. The research team found significantly ...

Novel vaccine approach offers hope in fight against HIV

... the scientists protected monkeys from infection by a virus closely related to HIVthe simian immunodeficiency virus, or SIVthat causes AIDS in rhesus monkeys. "We used a leapfrog strategy, bypassing the natural immune system response that was the target of all previous HIV and SIV vaccine ...

Drugs needed to preserve eggs for reproduction need to be given in stages

... ones, say scientists who have developed a mathematical model that predicts optimal time for loading and unloading these drugs. Their studies in rhesus monkey eggs, which are very similar to human eggs, show that a two-step process of easing into and out of the drugs needed to help protect eggs at ...

Beyond 'ooh-ooh, aah-aah'-- expert on monkey communication kicks off Darwin series, May 5

... in 1990 by the University of Chicago Press. Other species and research sites that are currently the focus of Seyfarth's research group include rhesus monkeys on Cayo Santiago, Puerto Rico; elephants in Sri Lanka; and geladas in Ethiopia. ...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

... respond to looming sounds sooner than their typically larger, stronger male counterparts -- though both groups perceive receding sounds equally. rhesus monkeys also spend less time looking at receding sounds than approaching sounds. "These reactions are influenced by evolutionary forces; it's a good ...

Potential new HIV drug may help patients not responding to treatment

... help HAART to work more effectively in these people. In the new study, researchers gave daily doses of a modified amino acid called D-1mT to 11 rhesus macaques infected with SIV. All of the macaques had been treated with ART for at least four months. Eight of the macaques had higher viral loads ...

How we see objects in depth: The brain's code for 3-D structure

... Zanvyl Krieger Mind-Brain Institute at The Johns Hopkins University. In the study, Connor and a postdoctoral fellow, Yukako Yamane, trained two rhesus monkeys to look at a computer monitor while 3-D pictures of objects were flashed on the screen. At the same time, the researchers recorded electrical ...

Parkinson's Disease Foundation announces award of $150,000

... debates associated with using embryonic stem cells. Dr. Zhang's laboratory will examine the potential of iPS cells by reverting skin cells of rhesus monkeys into iPS cells and directing the cells to become dopamine neurons. Next, Dr. Emborg and her colleagues will insert the dopamine neurons ...

Thumbs up -- a tiny ancestral remnant lends developmental edge to humans

... (now at the Yale University School of Medicine), and postdoctoral fellows describes a global survey they conducted of genomeshuman, chimpanzee, rhesus macaque, mouse, rat, and dog. They screened across these species to find the most conserved regions, but where humans had many more changes relative ...

July 2008 highlights

... Steve Jacoris, and Alice F. Tarantal. Endocrine Antecedents of Polycystic Ovary Syndrome in Fetal and Infant Prenatally Androgenized Female rhesus Monkeys. Biol Reprod 2008; 79: 154-163. Published online in BOR-Papers in Press on 2 April 2008; DOI 10.1095/biolreprod.108.067702 ....

First analysis of platypus genome may impact disease prevention

... and several different international consortia have succeeded in sequencing the genomes of several species in the past, most recently that of the rhesus macaque and the first marsupial, a small, South American opossum species. Each one gives us another piece of the puzzle, which brings us that ...

UC Davis researchers discover how HIV turns food-poisoning into lethal infection

... for their collaboration. Together, they developed a novel technique that allowed them to study early intestinal responses to Salmonella infection in rhesus macaques infected with simian immunodeficiency virus (SIV), an established model for HIV infection. We found that animals that had no SIV ...

Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity

... of occupational therapy and psychology at the University of Wisconsin-Madison and the studys lead author. Researchers studied 38 5- to 7-year-old rhesus monkeys born to mothers who either drank a moderate dose of alcohol every day during their pregnancies, were exposed to a mild 10-minute stressor ...

There is powerful evidence of evolution in human DNA

... scientifically informative remnants of our evolutionary ancestry trapped in the human genetic code. For example, the analysis of the chimpanzee and rhesus monkey genomes shows indisputable evidence of the human evolutionary relationship with other primates. Over 95 percent of our genome is identical ...

Human clones: New U.N. analysis lays out world's choices

... Clones have been achieved with mice, sheep, pigs, cows and dogs and U.S. researchers last summer accomplished the first cloning of a primate a rhesus monkey embryo cloned from adult cells and then grown to generate stem cells. National efforts to outlaw reproductive cloning of humans are easily ...

Study reveals possible genetic risk for fetal alcohol disorders

... Schneider's team analyzed data from an ongoing, long-term study into the impacts of moderate fetal alcohol exposure on behavior and brain function in rhesus monkeys. Although fetal alcohol syndrome was first recognized in children of alcoholic mothers, attention has shifted in recent years to moderate ...

Gene regulation, not just genes, is what sets humans apart

... journal Nature Genetics. His group looked at the regulatory sequences immediately adjacent to 6,280 genes on the DNA of chimps, humans and the rhesus macaque, a more distant primate relative that has 88 percent the same genes as humans. These regulatory stretches of DNA are where proteins bind to ...

Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps

... has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee ... among their genes. In its paper, the rhesus Macaque Genome Sequence and Analysis Consortium, ... of Health (NIH), compared the genome sequences of rhesus macaque (Macaca mulatta) with that of human (Homo ...

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

... Scientists investigating the genetic makeup of rhesus macaque monkeys, a key species used in biomedical research, have found the rhesus in Nepal may provide a suitable alternative to ... macaques are more closely related genetically to rhesus macaques from India ...

NHGRI announces latest sequencing targets

... including the chimpanzee (Pan troglodytes), the rhesus macaque (Macaca mulatta), the orangutan (Pongo ... similarities with humans. For example, the rhesus macaque is an essential research model for drug ... to the human immunodeficiency virus (HIV), the rhesus is widely recognized as the best animal model for ...

Genetic and environmental influences on alcohol consumption among rhesus monkeys

... Clinical & Experimental Research use rhesus monkeys to examine genetic and environmental ... behavior and alcohol consumption among rhesus macaques. For this particular analysis, study ... the first several months of life among infant rhesus monkeys had later effects on alcohol consumption. ...

Genetic links could unlock clues to leading cause of blindness

... German researchers bout a genetic link between rhesus monkeys with macular degeneration and humans ... markers for macular degeneration in humans and rhesus monkeys, findings recently published in the ... age-related macular degeneration in humans and rhesus monkeys. Dawson and other researchers have ...

Rhesus monkeys can assess the visual perspective of others when competing for food

... both from Yale University, have found that rhesus monkeys consider whether a competitor can or ... to steal food. Working with semi-free-ranging rhesus monkeys on the island of Cayo Santiago in Puerto ... Together, these results reveal not only that rhesus monkeys prefer to steal food from a competitor ...

Low levels of neurotransmitter serotonin may perpetuate child abuse across generations

... the University of Chicago shows. A research team found that when baby rhesus monkeys endured high rates of maternal rejection and mild abuse in their ... the Development of Monoaminergic Systems and Adult Abusive Parenting in rhesus Macaques" published in the current issue of Behavioral Neuroscience. ...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

... against a large-scale anthrax attack. In the study, two groups of rhesus macaques were exposed to very high amounts of anthrax spores by aerosol. ... of spores and incubation period after aerosol exposure. In one study, rhesus macaques were protected during a 30-day course of antibiotics after ...

Diabetes researchers pioneer islet cell xenotransplantation in primate studies

... were sent to the Yerkes Research Center for transplantation into diabetic rhesus macaques using an anti-rejection protocol developed by Drs. Christian ... (a second-generation high affinity derivative of CTLA4-Ig)9-11 on diabetic rhesus macaques transplanted with neonatal porcine islets. ...

Gene mutation linked to cognition is found only in humans

... a different, type I-specific splicing site and a significant reduction in type I neuropsin expression in human and chimpanzee when compared with the rhesus macaque, an Old World monkey. This pattern suggests that before the emergence of the type II splice form in human, the weakening of the type I ...

Jefferson scientists find rabies-based vaccine could be effective against HIV

... the effects of inserting two different viral proteins into the rabies virus genome, and using such viruses-based vaccines in preventing disease in rhesus macaques. One was a glycoprotein on the surface of HIV, while the other was an internal protein from simian immunodeficiency virus (SIV). They used ...

On the golf tee or pitcher's mound, brain dooms motion to inconsistency

... it on a trial-by-trial basis to performance during those trials," Churchland says. The Stanford team decided to do just that with the help of rhesus macaque monkeys. The monkeys were trained to perform a simple reaching task. When shown a green spot, they were rewarded with juice if they reached ...

HIV-1's high virulence might be an accident of evolution

... on previous studies that found that nef-deficient SIV failed to cause symptoms in a monkey species normally susceptible to disease, Kirchhoff said. rhesus macaques infected with the mutant virus had extremely low viral loads and "either no pathogenicity, or a markedly protracted disease course." ...

UF scientists test improved gene therapy method for hereditary heart conditions

... of our research is it's probably the first to demonstrate a physiologic correction of a genetic cardiac abnormality." Additional tests in rhesus monkeys conducted in conjunction with scientists at the California National Primate Research Center at the University of California at Davis showed ...
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