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Reverse in Biological News

Genes that control cell death fingered in age-related hearing loss

... around the world, there is currently no way to reverse the hearing loss, largely because of the ... "The goal, of course, is to prevent and even reverse age-related hearing loss, which is the third most ... now, there is nothing we can do to treat it or reverse it, so prevention is the focus." Frisina ...

Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder

... anti-cancer drug can prevent -- and even reverse -- potentially fatal cardiovascular damage in a ... team had previously found that FTI drugs could reverse structural abnormalities in skin cells taken from ... to be done to determine whether FTI drugs will reverse progeria-associated cardiovascular disease in ...

New study offers solution to global fisheries collapse

... management strategy called "catch shares" can reverse fisheries collapse. Where traditional "open ... Furthermore, the authors show that catch shares reverse the overall downward trajectory for fisheries ... suggests that we already have the tools to reverse the current global fisheries crisis. "Previous ...

UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes

... telomerase are telomerase RNA and telomerase reverse transcriptase. They are "recruited" to telomeres ... bodies depends on the presence of telomerase reverse transcriptase. The Terns lab took advantage ... Michael Terns. "Our results indicate that human reverse transcriptase is a key determinant in human ...

First successful reverse vasectomy on endangered species performed at the National Zoo

... National Zoo have performed the first successful reverse vasectomy on a Przewalski's horse ( E. ferus ... were confident that if they could successfully reverse the vasectomy, Minnesota would be able to sire a ... urologist who pioneered microsurgery for reverse vasectomies in humans and had been successful in ...

Researchers document rapid, dramatic 'reverse evolution' in the threespine stickleback fish

... There are not many documented examples of reverse evolution in nature, said senior author Catherine ... precisely that cleanup effort that sparked the reverse evolution, Peichel and colleagues surmise. Back ... We propose that the most likely cause of this reverse evolution in the sticklebacks is from the higher ...

Scientists unravel the genetic coding of the pea

... discovered the first high-throughput forward and reverse genetics tool for the pea (Pisum sativum), could ... phenotyped for use in both forward and reverse genetics studies. The team set up a pea ... detection of single-nucleotide mutations. This reverse genetic strategy can be applied to all types of ...

Paired microbes eliminate methane using sulfur pathway

... microbes that accomplish this feat do not simply reverse the way methane-producing microbes work, but use ... has been that these microbes simply use reverse methanogenesis, the process in which methanogenic ... first investigated the assumption that reverse methanogenesis was the method used by the ...

New data shows benefits of MitraClip for patients with mitral regurgitation

... function of the left ventricle (commonly known as reverse remodeling), according to data presented this ... of Echocardiography guidelines. Significant reverse Remodeling of the Left Ventricle 12 months after a successful MitraClip procedure, significant reverse remodeling of the left ventricle was ....

Researchers achieve major breakthrough with water desalination system

... saturated with calcium sulfate salts, accomplishing this with just one reverse osmosis (RO) stage. "In this specific field study by our team, in the first part of the reverse osmosis process, 65 percent of the water that was fed in was recovered as ...

Reverse evolution in real-time

... back in the ancestral environment, for 50 generations, to impose reverse evolution on the flies, and then looked at the genetic changes in certain ... some characteristics reverse-evolved rapidly, while others took longer. reverse evolution seems to stop when the populations of flies achieve adaptation ...

Gene therapy reversed heart damage in heart failure

... said that targeting the GRK2 enzyme with ARKct was sufficient to reverse heart failure even without concomitant metoprolol. The rats that ... effective at stopping the downward progression of the disease, they do not reverse the damage already done. That is where the ARKct gene therapy ...

New filtering technology has environmental, industrial applications

... The technology might be used in a water-purification technology called reverse osmosis, which now requires a "pre-filter" to remove oil. This "oil coalescence filter" is needed to prevent oil from reaching the reverse osmosis membrane, which is ruined by oil. These conventional oil ...

Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration

... ongoing Phase I/II human clinical trial of BHT-3021, a DNA vaccine to reverse the immune response that causes type 1 diabetes. BHT-3021 is an antigen-specific immunotherapeutic DNA vaccine designed to reverse the underlying autoimmune disease process in diabetes, and slow down or ...

A dash of lime -- a new twist that may cut CO2 levels back to pre-industrial levels

... lime to seawater. And they think it has the potential to dramatically reverse CO2 accumulation in the atmosphere, reports Cath O'Driscoll in SCI's ... is therefore 'carbon negative'. 'This process has the potential to reverse the accumulation of CO2 in the atmosphere. It would be possible to reduce ...

River damming leads to dramatic decline in native fish numbers

... have made proposals to management agencies, which, if implemented, could reverse the loss of native species not only in the Colorado but on a country or ... they have gathered, the scientists have put forward proposals for how to reverse the decline in native fish numbers. "We suggest to management agencies ...

New study shows that fetal cells to treat Parkinson's disease may not function long term

... it, individuals with Parkinsons disease received fetal cell transplants to reverse the loss in the brain of striatal dopamine. The individual described in ... what causes PD and the potential for cell replacement strategies to reverse the motor symptoms. ...

Human hormone blocker found to help prevent obesity and diabetes: study

... that mice injected with the GIP receptor antagonist - (Pro3)GIP - can reverse or prevent many of the metabolic abnormalities associated with obesity. ... GIP receptor antagonism using daily injections of (Pro3) GIP was able to reverse well established diet-induced obesity and related metabolic abnormalities. ...

CU-Boulder worm study sheds light on human aging, inherited diseases

... light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases, according to a new ... The findings could one day contribute to the creation of gene therapies to reverse or lessen the effects of mitochondrial diseases, the largest family of ...

New cancer drug delivery system is effective and reversible

... can change aptamers to target a different type of cancer, you can change the therapeutic molecules to fight cancer or other diseases, and you can reverse the dose," Cheng said. "That's a lot of tools in the toolbox. It has great potential." ...

Wastewater produces electricity and desalinates water

... in some parts of the world. Its availability in the future will be even more problematic. Many locations already desalinate water using either a reverse osmosis process -- one that pushes water under high pressure through membranes that allow water to pass but not salt -- or an electrodialysis process ...

Music is the engine of new U-M lab-on-a-chip device

... I can vary the strength of the individual notes within the chords to move a given drop faster or slower." Burns describes the set-up as the reverse of a bell choir. Rather than ringing a bell to create sound waves in the air, which are heard as music, this system uses music to create sound waves ...

Seals quickly respond to gain and loss of habitat under climate change

... Holocene climate change. We learned that new habitat emerging within the species' migratory range could be quickly taken advantage of, but that the reverse was not true. The movement patterns of seals from this Antarctic breeding site would have been unlikely to take them near other potential breeding ...

Cells use import machinery to export their goods as well

... called post-Golgi vesicles, export cargo made by the cell's protein factory. Scientists have long believed that other, similar vesicles handle the reverse function, importing life-supporting nutrients and proteins through an independent process. By using a finely honed type of microscopy to more ...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

... delicate balance of energy that is needed between conformational structures of proteins in a cell, leading to disease. If so, a drug might be able to reverse those kinds of imbalances." ...

Another JDRF partner moves research forward with collaboration agreement for diabetes treatment

... a wholly owned member of the Roche Group, to further develop and potentially commercialize a novel antigen-specific immunotherapeutic designed to reverse the immune response that causes type 1 diabetes. To date, JDRF has awarded more than $29 million in research funding to 25 companies through its ...

Specific genetic cause of fetal alcohol-related developmental disorders found

... control learning, memory and emotional behaviors. "In light of our current finding, we can begin testing specific dietary supplements that could reverse the epigenetic alterations that disrupt the regulation of Dio3," Sittig said. "When given to the mother or newborn, this might correct the imprinting ...

Simple drug treatment may prevent nicotine-induced SIDS: Study

... as hypoxiawhich may result in a higher incidence of SIDS. In the same study on rats, they found that the diabetic medication 'glibenclamide' can reverse the effects of nicotine exposure, increasing the newborn's ability to respond to hypoxia and likely reducing the incidence of SIDS. The findings ...

Liver disease 'shrunk' by blood-pressure drug

... A blood-pressure medicine has been shown to reverse the effects of early-stage liver failure in some patients. Newcastle University researchers analysed a small clinical trial of losartan, a drug ...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

... resulting in large numbers of people living with heart failure. This advance has lead to another health hurdle: The only therapy available to reverse the decline in cardiac function is heart transplantation, and donor hearts are very scarce. Clinical trials of myocardial stem cell therapy ...

Environmental exposures may damage DNA in as few as three days

... being used as targets of cancer drugs." Dr. Baccarelli said the study results indicate that early interventions might be designed which would reverse gene programming to normal levels, reducing the health risks of exposure. "We need to evaluate how the changes in gene reprogramming we observed ...

True grit

... of the tip is a matrix of larger and softer calcite crystals. While in most such materials a matrix of hard fibers contains a softer filling, the reverse is true for the urchins' tooth: a matrix of relatively soft calcite fibers holds the harder magnesium calcite crystals, which allows these crystals ...

Avian flu research sheds light on swine flu outbreak

... coughing." In his study, Perez used the avian H9N2 influenza virus, one that is on the list of candidates for human pandemic potential. Using reverse genetics, a technique whereby individual genes from viruses are separated, selected, and put back together, Perez and his team created a hybrid ...

DNA barcoding of mosquito species deployed in bid to end elephantiasis

... mostly due to human impacts population growth, industrial development, pollution and climate change," says Dr. Edwards. "Efforts to stabilize and reverse this trend are hampered by biodiversity knowledge banks that are incomplete, fragmented and not easily accessible to those who need them to set ...

Impact of floods on soils

... conditions. The authors believe that once the reducing reactions take place in the field and disaggregation has occurred, the process will not reverse itself because the natural drainage will carry away the released chemicals and the chemistry of the soil-water system will not return to the original ...

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

... provide additional insight into the mechanisms that act to selectively destroy the blood vessels supporting tumor growth and spread and also to reverse the ability of tumors to suppress the body's natural immune response, resulting in the mobilization of important inflammatory and other anti-tumor ...

FANTOM findings boost for biologists

... ). Further research published in BMC Bioinformatics highlights two new data-driven normalization methods for quantitative reverse transcriptase polymerase chain reaction (qPCR) experiments with larger data sets. Another study published in Genome Biology includes the first ...

2009 ASPB Summer Undergraduate Research Fellowship award announcement

... my adventure in plant biology in the summer of 2008, when I was first exposed to yeast hybrid systems. The project titled above is going to use a reverse 2-hybrid system to screen for mutated SAUR19 proteins that no longer interact with a known protein interactor. This project can both elucidate the ...

CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die

... signals can't be sent without helper enzymes like PTPs that remove phosphate molecules from specific locations, and kinase enzymes that perform the reverse role that of adding phosphates. Another vital piece of the puzzle in the current work involves Dr. Kim, who recently spent 15 months in the ...

Impact of floods on soils

... conditions. The authors believe that once the reducing reactions take place in the field and disaggregation has occurred, the process will not reverse itself because the natural drainage will carry away the released chemicals and the chemistry of the soil-water system will not return to the original ...
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(Date:7/31/2014)... By tracing nearly 3,000 genes to the earliest ... Florida scientists have created an extensive "Tree of ... next-generation DNA sequencing. , Among the study,s ... to small moths than to large ones, which ... The study also found that some insects once ...
(Date:7/31/2014)... many of the roughly 156,000 gas stations across ... in parts of underground gas storage tankscorrosion that ... groundwater, a source of drinking water. In recent ... many rapidly corroding gas storage tank components such ... with use of gasoline-ethanol blends and the presence ...
(Date:7/31/2014)... Neb., July 31, 2014 -- Do people make a ... mothers raise them that way? Is it a matter ... Nebraska-Lincoln and a colleague from Rice University say that ... some people lean left while others lean right. , ... and deep-seated psychology are at the core of political ...
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