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Retinitis in Biological News

Progression of retinal disease linked to cell starvation

... first step in vision. The incurable eye disease retinitis Pigmentosa, however, reveals a codependent ... "This is the first study linking cone death in retinitis Pigmentosa to a metabolic problem that suggests ... levels in the cones. Perhaps someday we can help retinitis Pigmentosa patients maintain their daylight ...

Scientists eye secrets of retinal regeneration

... of disabling or blinding eye diseases such as retinitis pigmentosa," explains senior author Dr. Ching-Hwa ... trafficking were crucial to a common eye disease, retinitis pigmentosa." retinitis pigmentosa, a genetic disorder affecting about ...

UCSF researchers identify new drug target for Kaposi's sarcoma

... the researchers said. Those include mononucleosis (Epstein-Barr virus), shingles (Varicella zoster virus), genital herpes (herpes simplex), retinitis (cytomegalovirus) and cancer (Kaposi's sarcoma). While therapies exist for these viruses, they often have negative side effects and are facing rising ...

Work in mice will contribute to the study of hereditary diseases that lead to blindness

... consisting of the induction of neuronal degeneration neuronal for intense light exposure in the mouse's retina that will be helpful for the study of retinitis pigmentosa (RP), a group of hereditary diseases which lead to blindness and affect more than one million persons a year all over the world. In ...

Case Western Reserve University receives $1.66m grant from NIH for otoprotection research

... in Ushers syndrome. Usher Syndrome (USH) is a clinically and genetically heterogeneous disorder characterized by congenital deafness and retinitis pigmentosa. It is the most common cause of deafness accompanied by blindness. *There are about 10-15,000 people with Usher syndrome in the United ...

Cats' eye diseases genetically linked to diseases in humans

... COLUMBIA, Mo. About one in 3,500 people are affected with retinitis pigmentosa (RP), a disease of the retina's visual cells that eventually leads to blindness. Now, a University of Missouri researcher has identified a ...

Gene therapy restores vision to mice with retinal degeneration

... cells found throughout the retina. "This is a proof of principle that someday we may be able to repair blindness in people with conditions like retinitis pigmentosa and macular degeneration," says Richard Masland, PhD, director of the Cellular Neurobiology Laboratory in the MGH Department of ...

Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

... of PDEs in vision may lead someday to better drug treatment for loss of eyesight from damaged retinas, such as occurs in night blindness and retinitis pigmentosa. ...

New gene discovered for new form of intellectual disability

... Addiction and Mental Health (CAMH) has discovered a new form of intellectual disability involving mental retardation (MR) along with the eye defect retinitis pigmentosa (RP). CAMH also discovered the previously unidentified gene that causes this disorder, CC2D2A. This scientific advance will help ...

RNA interference therapy heals growth deficiency disorder in a live animal

... Some other common dominant negative diseases include forms of colon cancer, deafness, muscular dystrophy, brittle bone disease, kidney disease and retinitis pigmentosa. The blueprint for a protein like growth hormone is genetically encoded in a series of special segments called exons. The instructions in ...

Restoring sight, advances in fertility treatments and better visibility for pilots at FIO

... goal of providing limited vision to those rendered blind by certain diseases, via a fully implantable retinal prosthetic device. In both retinitis pigmentosa and age-related macular degeneration V two of the most common causes of vision loss V the photoreceptor layer of the retina is destroyed, ...

Ophthalmologists implant five patients with artificial silicon retina microchip

... of five patients to treat vision loss caused by retinitis pigmentosa (RP). The implant is a silicon ... retinal diseases such as macular degeneration and retinitis pigmentosa, which cause blindness and vision ... legally blind. "As is commonly seen in with retinitis pigmentosa, these patients all have severe ...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

... of five patients to treat vision loss caused by retinitis pigmentosa (RP). The implant is a silicon ... retinal diseases such as macular degeneration and retinitis pigmentosa, which cause blindness and vision ... legally blind. "As is commonly seen in with retinitis pigmentosa, these patients all have severe ...

'Lucky 13' as new gene discovery offers further hope for childhood blindness

... John Marshall, Chairman of the Medical Advisory Board at the British retinitis Pigmentosa Society. "This dramatic discovery provides further information enabling us to combat blindness within the retinitis Pigmentosa group," says Professor Marshall. "The more genes we discover ...

Gene therapy for blindness clears hurdle in mice

... the gene is a step toward developing a gene therapy to treat people with retinitis pigmentosa, an inherited disease that attacks the light-sensing cells in ... that may be sufficient to maintain vision in people who are affected by retinitis pigmentosa," Gorbatyuk said. "The second step, introducing the normal gene ...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

... device in several patients. The patients all have retinitis pigmentosa with moderate-to-severe vision loss. ... Eye Institute at Johns Hopkins Medical Center. retinitis pigmentosa is a pathologic condition that is ... device may make it possible for those with retinitis pigmentosa to have a much better quality of ...

Researchers discover way to make cells in the eye sensitive to light

... could lead to therapies for treating some forms of blindness, such as retinitis pigmentosa. retinitis pigmentosa is a form of hereditary blindness where the rods and cones are ...

MU researcher placing eye implants in cats to help humans see

... According to Narfstrom, the preliminary results are promising. "About one in 3,500 people worldwide is affected with a hereditary disease, retinitis pigmentosa, that causes the death of retinal cells and, eventually, blindness," Narfstrom said. "Our current study is aimed at determining safety ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

... are converted to the images we see. In the majority of macular and retinal degenerative diseases, such as age-related macular degeneration and retinitis pigmentosa, it is the loss of photoreceptors that leads to blindness. Understanding the birth of photoreceptors In 2001, Swaroop's team first ...

Study provides first look at the 'birth' of a retina cell

... Rods greatly outnumber cones in the mouse and in humans. Damage to photoreceptors is at the root of eye diseases such as diabetic retinopathy, retinitis pigmentosa, and macular degeneration. In most instances, including age-related macular degeneration, rod photoreceptors die before cones. As the ...

'Prosthetic' retinal cells let blind mice see light

... protein into "inner retinal neurons" in a strain of mice with photoreceptor deficiency that resembles the defect in such inherited human disorders as retinitis pigmentosa. Unlike the retinal rods and cones that normally function as light-sensing cells in the eye, these retinal neurons are normally not ...

A new way of looking at molecular motors

... other. Myosins also help parasites enter and infect hosts. Defects in the motors play a role in a variety of human and animal disorders, including retinitis pigmentosa (which causes blindness), polycystic kidney disease, brain development defects, neurodegenerative diseases, muscular dystrophy, skin ...

Gene therapy works in mice to prevent blindness that strikes boys

... retinal damage. The treatment has promising implications for other genetic eye diseases that involve the eye's ability to process light, including retinitis pigmentosa, which affects about 200,000 people in the United States and is one of the most common inherited causes of blindness in people between the ...

Six previously blind patients detect light, motion, identify objects with retinal prostheses

... of the retina." Thus far, participants in the study have been people with little or no sight perception due to the degenerative eye disease retinitis pigmentosa (RP). Ultimately, however, the device is likely to be used for the millions of people suffering from age-related macular degeneration, or ...
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