Promising 3-year data: Saving limbs with drug-eluting stents
... site of angioplasty or stenting), the need for repeat
treatments and the continued progression of ... that these types of stents lessened the rate of repeat
procedures to open these small arteries, ... consequently less clinical recurrence requiring repeat
angioplasty, said Karnabatidis. "In the ...
Repeat C-section before 39 weeks raises risk of neonatal illness
... BIRMINGHAM, Ala. Women choosing repeat
cesarean deliveries and having them at term but ... who choose to have their babies delivered via repeat
cesarean at 37 or 38 weeks without a medical or ... performed in the United States each year are repeat
procedures, we undertook this large study to ...
After dinosaurs, mammals rise but their genomes get smaller
... animals and three plants, specifically with regard for the long terminal repeat
(LTR) sequences of transposable elements, a curious sort of "jumping" ... as much as 45 percent of an individual's total DNA. Long terminal repeat
sequences, part of that figure, make up about 8 percent of humans' total ...
Researchers gain insight into mechanism underlying Huntington's
... development of a specific type of genetic mutation known as trinucleotide repeat
expansions. Diseases associated with these mutations, including Huntington's disease, are called trinucleotide repeat
Findings were published today in Nature Structural & ...
Saved by junk DNA
... using yeast cells as Darwinian guinea pigs. Their results show that when a repeat
is present near a gene, it is possible to select yeast mutants that show vastly increased activity of this gene. However, when the repeat
region was removed, this fast evolution was impossible. 'If this was the ...
Biologists discover link between CGG repeats in DNA and neurological disorders
... divisions. Scientists at Tufts University have found that one such DNA repeat
not only stalls the cell's replication process but also thwarts the cell's capacity to repair and restart it. The researchers focused on this CGG repeat
because it is associated with hereditary neurological disorders such as ...
'Junk' DNA proves functional
... master proteins that control the expression of other genes, bind specific repeat
elements. The researchers showed that from 18 to 33% of the binding sites ... roles in cancer and stem cell biology are embedded in distinctive repeat
Over evolutionary time, these repeats were dispersed within ...
Diversity of plant-eating fishes may be key to recovery of coral reefs
... of their cover during the time period.
Hay and Burkepile attempted to repeat
their experiment with a different species of fish, but the underwater ... to expand the experiments to study the effects of additional species, and repeat
the studies in different areas, such as the Fiji Islands, where residents ...
Sociological research shows combined impact of genetics, social factors on delinquency
... (1) the 30-base pair (bp) promoter-region with a variable number tandem repeat
(VNTR) in the monoamine oxidase A (MAOA) gene, (2) the 40-bp VNTR in the ... a conditional interaction between repeating a school grade and the MAOA*2 repeat
(2R) allele in adolescent boys. For those who did not have the 2R allele, ...
Kansas state flower receives scientific attention
... inactive class of transposable elements of DNA, called long terminal repeat
"These elements are DNA sequences related to ... their host genome. Because of their replicative abilities, long terminal repeat
retrotransposons, when activated, can result in massive genomic expansion ...
Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols
... Beauty transposon-based transfection is a two-component system consisting of a transposase and a transposon containing inverted repeat/direct repeat
sequences that result in precise integration into a TA dinucleotide. The article is freely accessible on the website for Cold Spring Harbor ...
Brain difference in psychopaths identified
... scientists and the criminal justice system.'
While psychopathy is strongly associated with serious criminal behaviour (eg rape and murder) and repeat
offending, the biological basis of psychopathy remains poorly understood. Also some investigators stress mainly social reasons to explain antisocial ...
New piece found in the puzzle of epigenetics
... this region are modified biochemically. Thus, it is absolutely essential for the synthesis of snRNA that the amino acid serine at position 7 of this repeat
sequence is provided with an additional phosphate group. If this is lacking, mRNA will be produced, but not any snRNA. The reason for that is ...
Bird songs change with environment
... to be garbled by reverberation.
"Young male sparrows learn to sing by listening to adult males nearby," she explains. "Juveniles likely learn and repeat
the songs they hear most clearly." Since the slower songs come through loud and clear in leafy surroundings, those are the ones that are learned and ...
Small molecules might block mutant protein production in Huntington's disease
... life it appears. A person with the disease carries one normal copy of the gene and one mutated copy in his or her cells.
In Huntington's, this CAG repeat
occurs in a gene called huntingtin, and in Machado-Joseph, it occurs in a gene called ataxin-3. A person with Huntington's can have up to 100 CAG ...
Novel lung cancer vaccine shows promise in fighting early-stage lung cancer
... lung cancer patients whose tumors expressed MAGE-A3, preliminary results showed that the vaccination reduced the risk of recurrence and the need for repeat
The vaccination may be a promising alternative treatment solution for lung cancer patients that may not be ideal candidates for ...
Hebrew University professor's work leads to FDA approval for product
... of adhesions following heart surgery is of special concern, since they may affect cardiac function. Furthermore, in the frequent cases where repeat
operations are required, adhesions obscure cardiac landmarks, making the procedure potentially life-threatening to the patient due to inadvertent ...
Interventional treatment can be recommended as first-line treatment for 'silent killer'
... interventions (or the necessity of performing additional procedures to correct complications from a prior treatment) and whether the need for repeat
interventions could be predicted by surveillance imaging. "Most importantly, the overall rate of secondary interventions after endovascular repair ...
Freezing prostate cancer does a man's body good
... traditional approaches do, noted the professor at the University of Central Florida. "You can go home on the same day of the procedure, and you can repeat
the treatment, if needed, in later years," said Onik. Additionally, Onik presented results of a 3-D biopsy method that provides superior information ...
A new way to assemble cells into 3-D microtissues
Another variable is the complexity of the synthetic DNA sequence. The researchers can specify the complexity for example, from a simple repeat
of two bases such as cytosine and adenine ... on one strand, which binds to a complementary repeating sequence of thymine and guanine ....
Scientists find black gold amidst overlooked data
... the most popular and reliable method in recent years according to the study authors. SAR imagery can be very expensive, the authors note, and timely, repeat
coverage is not always possible, particularly in tropical regions.
Using imagery from the Moderate Resolution Imaging Spectroradiometer (MODIS) ...
Sequencing of sorghum genome completed
... including many plant species and the human genome. By using paired sequence reads instead of single sequence reads, the scientists can jump over repeat
sequences, constituting about 62% in sorghum, and produce an accurate and contiguous picture of the entire sorghum genome.
"I was very ...
The global impact of climate change on biodiversity
... the new samples. Armed with the data from 1965, moth-trapping equipment, tents, sleeping bags and rations, I-Ching and colleagues set out to repeat
the original survey.
"Photographs from the 1965 expedition led us back to exactly the same sites sampled 42 years ago", said Dr Suzan Benedick, ...
Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases
... evidence indicates that the cargoes being trafficked are also misdirected by faulty signaling, due to pathogenic mutations in the leucine-rich repeat
kinase 2(LRRK2) gene, Dr. Farrer says.
The findings may also shed light on other neurodegenerative disorders, the researchers say. In Alzheimer's ...
A BBVA Foundation project comes up with a system enabling detection of cetacean hearing loss
... ocean deeps, which conclude that this marine mammal is capable of detecting a 25 cm squid at a distance of more than two kilometers by means of the repeat
emission of sonar clicks. But the presence of intrusive, man-made sound sources can impair this capacity, potentially disrupting the species in its ...
American Chemical Society's Weekly PressPac -- Nov. 19, 2008
... for certain diseases. JS
ARTICLE #2 FOR IMMEDIATE RELEASE
"Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) repeat
RNA-MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)"
DOWNLOAD FULL TEXT ARTICLE
TECNALIA investigates advanced biomaterials to make more reliable and hardwearing medical implants
... of novel biomaterials which enable an extension of the functions of the implant throughout the whole life of the patient, in such a way that repeat
surgical operations are avoided; the reliability and the integration of the implants are enhanced and tissue rejection avoided; the recuperation ...
Wetlands expert: China should think outside the flooding box with Three Gorges Dam
... miles equivalent to the land area of Hong Kong. Then by summer the water level will drop 100 feet, and the cycle of flooding and receding water will repeat
every year after that.
The region will become home to an entirely new ecosystem as an unprecedented amount of water covers what used to be dry ...
'Himalaya -- Changing Landscapes' photo exhibition draws attention to the impacts of climate change
... photo exhibition aims to raise awareness of the impact of climate change and of the new challenges facing the mountain people. The stunning repeat
panorama views of mountains and glaciers are accompanied by images of the Himalayan people and their stories, as well as photographs of the ...
Risk and reward compete in brain
... multiple areas, lesion-based studies usually cannot pinpoint the role of smaller brain regions.
So Bechara's group at the institute decided to repeat
the experiment with fMRI.
"We were interested in how normal people perform this task. What's going on in their brain?" asked first author Gui Xue, ...
Structures of important plant viruses determined
... to a standard in this case, tobacco mosaic virus," said Brookhaven's Joe Wall. "Knowing the mass per unit length, the subunit size, and the axial repeat
gives the number of subunits per turn." According to Stubbs, "The number of molecules per turn in the helix is the key. It allowed us to determine ...
Researchers develop new self-training gene prediction program for fungi
... their gene prediction algorithms to accurately interpret even more complex eukaryotic genomes.
"There are genome sequencing projects where large repeat
populations, a significant number of pseudogenes or substantial sequence inhomogeneity hamper ab initio gene prediction and we're ready to tackle ...
ESA trains next generation of atmospheric scientists
... of the next generation," Dr Kerridge said. "I've been very impressed by the standard of questions and comments from the students and I hope ESA will repeat
this exercise in the future."
Surviving the revolution, easier than withstanding human use and abuse
... avoid the problem observed by Spanish-born, American poet and philosopher George Santayana: 'Those who cannot remember the past are condemned to repeat
it'," says Robert E. Loeb, professor of biology, Penn State Dubois campus.
The researchers suggest that beside long term monitoring, regular ...
During Olympics, Cornell's Max Zhang studies air-quality in Beijing
... They used real-time analytical instruments to capture the changes in particle size and concentrations in a matter of seconds.
Zhang plans to repeat
tests in Beijing during the Olympics, and then again a year later. The study is supported by Cornell's Jeffrey Sean Lehman Fund for Scholarly ...
Failure of the 1st attempt at assisted reproduction justifies at least 1 additional cycle
... in Barcelona today (Tuesday): "The purpose of this study was to try to identify, at least in our practice, if a patient in a certain age group should repeat
a cycle and how many. We found that the overwhelming majority of women who became pregnant (96%) achieved pregnancy by their second attempt, although ...
Bird watchers, space technology come together in Montana State University study
... three routes.
Park ornithologist at the time, he would drive to a designated spot and identify the birds there. Then he'd drive another half mile, repeat
the process and continue until he had stopped 50 times in 24.5 miles for the North American Breeding Bird Survey. Trying to finish before the birds ...
Study finds Chinese food good for your heart
... on patients who have suffered a heart attack found that a partially purified extract of Chinese red yeast rice, Xuezhikang (XZK), reduced the risk of repeat
heart attacks by 45%, revascularization (bypass surgery/angioplasty), cardiovascular mortality and total mortality by one-third and cancer mortality ...
USGS science picks -- leads, feeds and story seeds
... this October 21 marks an important milestone the past five large earthquakes on the Hayward Fault have been about 140 years apart on average, and a repeat
of this powerful earthquake could happen at any moment. A recent report indicates that the Hayward Fault is the most likely fault to produce a ...
Yale Environment 360 magazine launches online
... analysis and debate on global environmental issues," said Yale President Richard C. Levin. "In founding Yale Environment 360, the University hopes to repeat
its success with YaleGlobal, an online journal devoted to exploring globalization. In the six years since its launch, YaleGlobal has had 18 million ...