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Predictive in Biological News

VistaGen, WARF sign license agreement for human embryonic stem cell technology

... customized, next-generation, stem cell-based predictive toxicology and drug discovery screening assays to ... value of human embryonic stem cell biology for predictive toxicology, drug discovery screening and drug ... never before possible. The company plans to use predictive information from its stem cell-based "Clinical ...

New, noninvasive prostate cancer test beats PSA in detecting prostate cancer

... positive for prostate cancer. PSA was not predictive at all, Chinnaiyan said. You might as well have ... biomarkers achieved a specificity and positive predictive value of greater than 75 percent, which they ... person does not have a disease, and the positive predictive value is the proportion of patients with positive ...

Emory, Ohio State launch partnership in predictive and personalized health care

... Medical Center have formed the Alliance for predictive and Personalized Health--a partnership aimed at ... and chairman of Emory Healthcare. "Personalized, predictive health care will provide the best prevention and ... and Ohio State builds on innovative programs in predictive and personalized medicine in Emory's Woodruff ...

From cars to cancer: UH professor employs auto industry tools for tumor therapy

... physics at the University of Texas M.D. Anderson Cancer Center, to develop predictive models of tumors that hopefully will increase the accuracy of radiation ... number of CT scans, and the radiation plans will be developed using the predictive models." Traditional computed tomography sessions, also known as CT ...

Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment

... Dr. Sreekumar says. Elevated levels of PSA, a protein, are not always predictive of cancer, which means a lot of men get unnecessary biopsies. PSA ... at MCG, he's looking to expand the number of metabolites known to be predictive of prostate and other cancers. In prostate cancer, he's beginning with ...

Phylonix to present at 2009 Society of Toxicology Annual Meeting

... Monday, March 16, 1:00 pm - 4:30 pm 390 Poster / Board 207 "Zebrafish: A predictive Model for Assessing P-Glycoprotein Inhibitors" Tuesday, March 17, 9:00 ... March 18; and is also sponsoring a lunch hour workshop, "Zebrafish: A predictive Model for Assessing Safety and Toxicity," on Monday, March 16 from 12:15 ...

Dana-Farber oncologists present at ASCO GU -- predict prostate cancer survival using Source MDx test

... patients. In the study, circulating tumor cell (CTC) counts were not predictive of survival. In fact, the highest CTC counts (931 and 263) were found in ... humoral immunity in CRPC patients with higher mortality. "The six genes predictive of more lethal castration-resistant prostate cancer in this trial suggest ...

Predicting risk of stroke from one's genetic blueprint

... information from 569 hospital patients, the researchers showed that their predictive model could estimate an individual's overall risk of cardioembolic stroke ... model looks for factors, combines them and finds out which are the best predictive factors," explains Ramoni. "It's never one factor at a time, it's always ...

Study on wildlife corridors shows how they work over time

... seeds, similar to poppy seeds. For birds, the researchers had great predictive power. There were more bird-dispersed species in the connected then in ... of unassisted dispersal and the impacts of wind, we'll have better predictive power," Orrock said. ...

Genetic Engineering & Biotechnology News reports on the trend toward predictive toxicogenomics

... out a new compound's mechanism of action and eventually developing a predictive toxicology technique, according to the November 15 issue of GEN . ( ... of biomarkers for kidney toxicity. Groups such as The C-Path predictive Safety Testing Consortium are examining published toxicogenomics multiple ...

Arbor Vita presents new data on cancer diagnostic at EUrogin

... today on its rapid, point-of-care prototype HPV test with a high positive predictive value for cervical cancer and pre-cancer. Targeted for use throughout the ... cause of cervical cancer. E6 is a diagnostic marker of high positive predictive value for cervical cancer because of its clinically relevant activity. ...

Paleozoic 'sediment curve' provides new tool for tracking sea-floor sediment movements

... "The new Paleozoic sea-level sediment curve provides a way of deriving predictive models of sediment migration on continental margins and in interior ... These sea level increases and decreases are used extensively, Haq said, in predictive models of sediment movements. The current Science paper is a shorter ...

Gaining ground on sickle cell disease

... also factors in age, sex, degree of anemia and HbF levels, the model's predictive ability was enhanced. The findings need to be validated in large, ... might eventually want to genotype patients for these variants, to get more predictive information on their disease," Sankaran says. Finally, once this study ...

Scientists set out to measure how we perceive naturalness

... from across the country. This will then be used to help build the first predictive model of how we judge naturalness. As well as the real-time experiment ... fabric and stone, but once the data is combined the aim is to produce a predictive computer model that will work for other materials. If successful the range ...

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

... is seen in the biopsy. By adding the analysis of PTOV1, the positive predictive value (the chance that the HG-PIN lesion will become cancerous) of all ... those with a score of less than 100, is 34 percent, and the negative predictive value (the chance that the HG-PIN lesion will not become cancerous) is ...

Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines

... of Internal Medicine. SCORED demonstrates greater accuracy and greater predictive power in identifying individuals at high-risk for CKD than KEEP. In ... a sensitivity of 86 to 92 percent and a specificity of 24 to 35 percent. predictive values (the chance that a positive or negative test result will be ...

New lab test offers better prediction of HIV microbicide safety

... of the gels nonoxynol-9 and cellulose sulfate actually increased the risk of HIV infection in women. "Our goal was to develop assays that are predictive of safety before proceeding to clinical trials that typically cost millions of dollars, involve thousands of women, and take many years," says study ...

Seals quickly respond to gain and loss of habitat under climate change

... within and among species. Tracking these processes during periods of change reveals mechanisms for the establishment of populations, and provides predictive data on response to potential future impacts, including those caused by climate change. Professor Rus Hoelzel said: "In general, this approach of ...

Will IVF work for a particular patient? The answer may be found in her blood

... not," she said. The researchers found that the peripheral blood gene expression 'signature' (also known as the transcriptome) before IVF was predictive of IVF outcome. This finding demonstrates the power of high-dimensional technology in biomarker discovery, and highlights the potential for ...

NSF provides $3.4 million to study climatically important Agulhas Current

... index for the Indian Ocean, which can be linked to other climate indices, such as the Atlantic Meridional Overturning, and hopefully improve our predictive capabilities for the future," Beal added. ...

New research shows dinosaurs may have been smaller than we thought

... The problem occurs as a result of transforming the data, which changes the properties of the original data, and creates biases that can affect the predictive results obtained from the equation. Birchard and his colleagues realized there was an error when they used the equation to determine the weight of ...

Green tea may affect prostate cancer progression

... for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression. "The investigational agent used in the trial, Polyphenon E (provided by Polyphenon Pharma) may have the ...

Discovery of a water snake that startles fish in a way that makes them flee into its jaws

... react with a C-start and the snake almost always misses those that don't react reflexively." Catania's next step will be to determine whether this predictive capability is hard-wired or learned. To do so, he hopes to obtain some baby snakes that have just hatched and videotape their first efforts to catch ...

Promising device snags young inventors coveted spot at IShow

... in a mere 10 seconds. When combined, those daily measurements offer a good picture of the health of the patient's cardiovascular system and can be predictive of acute episodes, such as heart failure. If used daily, the device will indicate when a patient needs to seek medical attention, potentially ...

Scientists tackle the mystery of white-nose syndrome in bats

... sites to clean sites on clothing and equipment. The purpose of the meeting is to determine the present knowledge of the disease and to develop predictive models to determine how and under what conditions the disease might spread. Ultimately, the models would be used to help devise appropriate ...

Scientists examine perceptions of risk and the spread of disease

... way if we cannot reasonably inspect everything. We need to look at how to best balance the risks and the costs." The group aims to develop predictive models to forecast the risks associated with emerging infectious diseases in humans, livestock, wildlife, and plants, and to collaborate in ...

Scientists unravel the mystery of white-nose syndrome

... sites to clean sites on clothing and equipment. The purpose of the meeting is to determine the present knowledge of the disease and to develop predictive models to determine how and under what conditions the disease might spread. Ultimately, the models would be used to help devise appropriate ...

Scientists examine human behavior and the threat of disease

... way if we cannot reasonably inspect everything. We need to look at how to best balance the risks and the costs." The group aims to develop predictive models to forecast the risks associated with emerging infectious diseases in humans, livestock, wildlife, and plants, and to collaborate in ...

Swiss Initiative in Systems Biology launches new projects

... of computer simulations of entire biological systems based on mathematical models is equally important. This allows biology and medicine to become a predictive quantitative science, which in the long term will simplify processes such as the discovery of novel and more personalized medications. ...

Illinois Soil Nitrogen Test measures microbial nitrogen

... of gaseous ammonia liberated by heating the soil with strong alkali in a Mason jar. Several studies have provided evidence that the ISNT is predictive of yield response by corn to nitrogen fertilization, but there have also been negative evaluations in which concern has been raised that test values ...

Does mom know when enough is enough?

... per day at 6 months approached significance in predicting weight gain from 6 to 12 months, and maternal sensitivity to the infants' signals reached predictive significance, but in a negative directionindicating that mothers who were less sensitive to satiety cues had infants who gained more weight. ...

Personalized treatment for early lung cancer

... is particularly important for early stage disease when following surgery, decisions about preventive therapy are based on specific prognostic and predictive factors." Prof Walter Weder, head of thoracic surgery at the University of Zurich in Switzerland, adds: "At the meeting, several research groups ...

Collaboration leads to success: Most powerful computer of its kind in western N.Y. available worldwide

... on platforms for monitoring grid systems, for providing a single point-of-entry portal and for solving intricate problems involving node swapping, predictive scheduling and resource management. MCIL has been responsible for grid-enabling critical applications in areas such as structural biology, ...

News from the April 2009 Journal of the American Dietetic Association

... Dietary Intake, Eating Habits and Metabolic Syndrome in Korean Men Assessing Dietary Variety in Children: Development and Validation of a predictive Equation Food Groups and Renal Cell Carcinoma: Results from a Case-Control Study Consumption of Recommended Food Groups among Children from ...

Blood test predicts chance of dementia

... plays a role in the death of brain cells in other diseases of the brain, such as Alzheimer's disease and Amyotrophic Lateral Sclerosis (ALS). predictive test On the basis of their research, Kristel Sleegers, a scientist in Van Broeckhoven's team, has developed a test for measuring the quantity of ...

European Multidisciplinary Conference on Thoracic Oncology

... European cooperation and scientific exchange . Meeting highlights: New developments in understanding lung cancer biology Prognostic and predictive factors in non-small-cell lung cancer Critical appraisal of imaging tools in thoracic oncology Individualized staging: practical implications ...

Using hair to manage HIV/AIDS and predict treatment success

... reflects the rate of pill consumption sustained by patients over weeks, not days. Assessing an average level of drug exposure over time may be more predictive of treatment response than the "snapshot" of exposure provided by a single plasma level of medication, Gandhi said. "Hair sampling for ...

New technique for cancer screening

... tumor deposits in lymph nodes with known micrometastatic disease in a well defined cohort of prostate cancer samples. This may lead to new and better predictive and staging methods for prostate cancer patients. ...

Anadys Pharmaceuticals to Present at the Roth OC Growth Stock Conference

... any results expressed or implied by such forward-looking statements. For example, the results of preclinical and early clinical studies may not be predictive of future results, and Anadys cannot provide any assurances that ANA598 or ANA773 will not have unforeseen safety issues, will have favorable results ...

February 2009 Geology and GSA Today media highlights

... classification approaches, and inconsistent stratigraphies that ultimately are not well suited for describing glaciated surficial deposits in a predictive fashion. Here, the authors propose a classification of Quaternary glacial deposits based on the combined use of conventional lithostratigraphic and ...
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