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Polycystic in Biological News

UAB's Lisa Guay-Woodford earns top international nephrology prize

... Prize for Advancement in the Understanding of polycystic Kidney Disease, given by the The PKD Foundation ... for her original contributions to the field of polycystic kidney disease (PKD) research, clinical practice ... focuses on the molecular genetic determinants of polycystic kidney disease. She is trained and certified as a ...

July 2008 highlights

... Prenatal programming. polycystic ovary syndrome, or PCOS, is among the most common causes of infertility, ... Dumesic, Steve Jacoris, and Alice F. Tarantal. Endocrine Antecedents of polycystic Ovary Syndrome in Fetal and Infant Prenatally Androgenized Female Rhesus ...

Rong Li Lab identifies new role of inflammatory protein in PKD and a possible treatment

... may also have a role in the formation of cysts in Autosomal Dominant polycystic Kidney Disease (ADPKD) one of the most common life-threatening genetic ... role in the transition from normal tubule development to the onset of polycystic Kidney Disease (PKD) in individuals predisposed for the disease." ...

Continuous oral contraceptives better at easing pain, bleeding

... desired, such as acne, hirsutism, premenstrual syndrome, endometriosis and polycystic ovary syndrome. But there have been few detailed studies of ovarian ... oral contraceptive pills to treat such chronic medical conditions such as polycystic ovary syndrome, endometriosis and premenstrual syndrome, where additional ...

UT Southwestern researchers disrupt biochemical system involved in cancer, degenerative disease

... body tissues. Misregulation of cellular responses to Wnt proteins, however, is associated with a broad range of diseases including Alzheimer's and polycystic kidney disease, cancer and type 2 diabetes. In the current study, the researchers used cultured mouse cells that were engineered to glow green ...

Low sperm count may be associated with prenatal testosterone excess

... Dr. Recabarren. First, the exposure may be a product of increased sexual steroids in the maternal environment due to a hormonal condition such as polycystic ovary syndrome. Second, humans are exposed to several industrial pollutants which can act as steroid mimics, causing the body to inhibit or ...

NYU scientists identify critical protein complex in formation of cell cilia

... School of Medicine and Cancer Institute, and first author of the paper. "Defective cilia are implicated in a wide range of serious illnesses such as polycystic kidney disease, retinal degeneration, and neurological disorders. Inappropriate activation of signaling molecules that normally reside at the primary ...

Chemical compound prevents cancer in lab

... that can change certain parts of a cell and affect its growth. Among the diseases and conditions being studied for treatment with Flex-Hets are polycystic kidney disease, kidney cancer and ovarian cancer. Benbrook and her research team have patented the Flex-Het discovery and hope to start clinical ...

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

... surgery on Thursday, Jan. 10. Sharon Flood of Pingree Grove, Ill. donated her kidney to her brother Steven Yelk of Gurnee, Ill., who suffers from polycystic kidney disease (PKD), which causes cysts filled with fluid to form throughout the kidneys. Eventually, these cysts take over the healthy kidney ...

Too much sugar turns off gene that controls the effects of sex steroids

... protein, then more testosterone and estrogen will be released throughout the body, which is associated with an increased risk of acne, infertility, polycystic ovaries, and uterine cancer in overweight women. Abnormal amounts of SHBG also disturb the delicate balance between estrogen and testosterone, which ...

Green alga genome project catalogs carbon capture machinery

... for human diseases associated with the fine hair structures of the cilia and flagella--for instance, the neurological movement disorder dyskinesia; polycystic kidney disease (PKD); and some forms of liver, respiratory and retinal degeneration disease. ...

'Chlamy' genome holds clues for renewable energy, the environment and human health

... also holds clues to human diseases that result from defects in flagella and cilia. These include dyskinesia, a neurological movement disorder, and polycystic kidney disease. ...

Drug could improve pregnancy outcomes in wider range of women with insulin resistance

... of obstetrics and gynecology. The finding, published online in Diabetes, suggests that Metformin could benefit women with type 2 diabetes or polycystic ovary syndrome (PCOS). About 8 percent of women trying to conceive have insulin resistance, Moley says, and even more are suspected to be borderline. ...

Scientists discover that widely available drug also helps fight kidney disease

... known as ADPKD, short for autosomal-dominant polycystic kidney disease. In the U.S., the number of ... rapamycin-treated patients and found that their polycystic kidneys shrank in size by 25% over two years. The polycystic kidneys in a control group showed no change. ...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

... developed enlarged bellies and died within three to four weeks of their birth. Scientists initially assumed that the mutation was causing a form of polycystic kidney disease, but a follow-up study more than a decade later showed that passage of urine from the kidney was blocked, and the condition was ...

One-third of adults with diabetes still don't know they have it

... or higher have had diabetes that developed during pregnancy (gestational diabetes) or have given birth to a baby weighing more than 9 pounds have polycystic ovary syndrome, a metabolic disorder that affects the female reproductive system have acanthosis nigricans (dark, thickened skin around neck or ...

A new way of looking at molecular motors

... infect hosts. Defects in the motors play a role in a variety of human and animal disorders, including retinitis pigmentosa (which causes blindness), polycystic kidney disease, brain development defects, neurodegenerative diseases, muscular dystrophy, skin pigmentation problems, and genetic hearing loss. ...

Scientists analyze chromosomes 2 and 4

... Project along with the DOE. Chromosome 4 has long been of interest to the medical community because it holds the gene for Huntington's disease, polycystic kidney disease, a form of muscular dystrophy and a variety of other inherited disorders. Chromosome 2 is noteworthy for being the second largest ...

Research shows smoking adds a decade to reproductive age of IVF patients

... cause of subfertility into four categories ?fallopian tube problems, male subfertility, unexplained fertility, and other causes (mainly women with polycystic ovarian syndrome or endometriosis) ?and analysed first cycle treatment results for the first three causes. Of the total, 1,828 of the first IVF ...
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