Protein that regulates hormones critical to women's health found in pituitary
... were unknown until now in a specific area of the pituitary
gland. Like someone at a control knob, the ... two decades has studied the powerful pea-sized pituitary
located at the base of the brain.
For ... his team showed that Viagra acts in the posterior pituitary
by enabling electrical impulses to release more ...
Gene's newly explained effect on height may change tumor disorder treatment
... in Gutmann's laboratory, noticed that the pituitary
glands, which produce growth hormone, also were ... to explore the role of the NF1 gene in the pituitary
gland and the hypothalamus, a brain region that controls pituitary
gland production of growth hormone.
Scientists find stem cells for the first time in the pituitary
... first time identified stem cells that allow the pituitary
glands of mice to grow even after birth. They ... muscle, and other tissues.
Looking at the pituitary
One place where stem cells had been suspected but never found is the pituitary
gland. This organ, which in people is about the ...
RNA interference therapy heals growth deficiency disorder in a live animal
... problem: deterioration and death of cells in the pituitary
gland that produce growth hormone. As a result, ... their growth but actually killed the cells in the pituitary
that produce growth hormone.
This came as a real ... the next problem was how to deliver it to the pituitary
gland which, in the case of the mouse, is the ...
Study finds Viagra increases release of key reproductive hormone
... oxytocin released by stimulation of the posterior pituitary
gland, a small structure directly underneath the ... "The same thing is happening in the posterior pituitary
- Viagra will not induce the release of oxytocin ... he says. The cells that supply oxytocin to the pituitary
come from a brain structure called the ...
Fireflies and jellyfish help illuminate quest for cause of infertility
... supplies of breast milk in nursing mothers but can be overproduced by some pituitary
tumours, causing infertility.
Prolactin has been linked to more than ... cells producing prolactin throughout the body. This included the pituitary
gland, the thymus an organ in the chest which helps protect against ...
Major NSF grant boosts UNH research on hormonal genomics
... grant from the National Science Foundation (NSF) for research on brain and pituitary
hormones and receptors.
With the four-year grant, Sower will build ... and functional studies of brain gonadotropin-releasing hormone and pituitary
gonadotropins which govern egg and sperm maturity in sea lampreys ...
Will IVF work for a particular patient? The answer may be found in her blood
... the achievement and maintenance of pregnancy," said Dr. Allen.
"We found that the gene expression profiles in blood of patients at the time of pituitary
down-regulation showed interesting patterns of gene clustering. Over 200 genes were differentially expressed in patients who went on to achieve an ...
A biological basis for the 8-hour workday?
... liver," says Hogenesch. Using improved statistical methods also led to better accuracy. "We were able to more precisely say that, for example, the pituitary
gland has 10-fold fewer oscillating protein transcripts than the liver, and cell-autonomous models have 10-fold less than that."
Salk researchers develop novel glioblastoma mouse model
... the work described to date pertains to glioblastoma, Verma and his team are currently using this methodology to investigate lung, pancreatic, and pituitary
September 2008 Biology of Reproduction highlights
... Proteomes to unravel gonadotrophs
Although the basic developmental lineage of pituitary
gonadotrophs is known, it has been harder to associate specific changes in gene expression with maturation due to the limited cell population. In an ...
Disabling mouse enzyme increases fertility
... St. Louis, May 16, 2008 Changing the sugars attached to a hormone produced in the pituitary
gland increased fertility levels in mice nearly 50 percent, a research group at Washington University School of Medicine in St. Louis has found. The ...
Excellence in open access research celebrated at BioMed Central awards dinner
... Reports Award. The winning entry for this inaugural award was:
JMCR Award - Phuong Mai
'A possible new syndrome with growth-hormone secreting pituitary
adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report'
Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young investigators
... PhD, at Harvard University, Cambridge, Massachusetts, is investigating causes and effects of stress hormone ACTH perturbation, a hallmark of certain pituitary
cancers, in the brain.
Daniel F. Jarosz, PhD , with his sponsor Susan L. Lindquist, PhD, at the Whitehead Institute for Biomedical Research, ...
Temperament linked to onset of cancer and early death in female rats
... that temperament and die earlier from mammary and pituitary
tumors than do their more adventuresome sisters, ... The breed is prone to development of breast and pituitary
tumors. In order to minimize the differences in ... found similar life span results for females with pituitary
The researchers also monitored ...
New brain hormone puts brakes on reproduction
... releasing hormone (GnRH). GnRH stimulates the pituitary
gland to activate the reproductive system, ...
Researchers have long sought inhibitors of pituitary
gonadotropins, but many had come to believe that ... communicates via a blood portal with the anterior pituitary
and stimulates production of the hormones ...
Growth hormone is not the anti-aging bullet for healthy adults
... healthy elderly."
Human growth hormone, a protein produced by the pituitary
gland, helps regulate growth during childhood and metabolism in adults. ... estimated that a year's supply for an adult with GH-deficiency caused by pituitary
disease would cost between $7,500 and $10,000 per year. Estimates of the ...
Runners -- Let thirst be your guide
... their kidneys can excrete. The hormone that determines how much fluid a kidney can excrete is arginine vasopressin (AVP), which is released from the pituitary
gland when a person is becoming dehydrated in order to force the kidneys to conserve water. At rest, a person’s AVP level is low and can be ...
The influence of the menstrual cycle on the female brain
... and testicles), which interact with estrogen receptors, progesterone or androgens.
7. Luteinizing hormone (LH) is a hormone produced by the pituitary
gland. Its main role is to trigger ovulation, which occurs between 36 and 48 hours after the LH peak.
An increase in brain activity with ...
Studies look at how genes affect antipsychotic drug response
... may elevate prolactin levels and cause weight gain in children ages 8-18 who suffer from pediatric bipolar disorder. An increase in prolactin (a pituitary
hormone that may affect bone development) or weight gain occurs in some but not all of these young patients.
"We are trying to determine if some ...
Buildup of damaged DNA in cells drives aging
... levels of growth hormones in the progeroid mice and ruled out the possibility that this suppression was due to problems with their hypothalamus or pituitary
glands, which regulate growth hormone secretion. Furthermore, they demonstrated that if normal adult mice were exposed to a drug that causes DNA ...
Leptin found to control appetite and limb development in frogs
... but it's clear that it does lots of other jobs," he said. The hormone is known to be part of a family of proteins called cytokines that includes pituitary
growth hormone, and it has been found to increase cell proliferation in the brains of rats.
Leptin is also found in late-stage fetal humans, ...
Growth hormone is made in the brain, report scientists
... in the brain.
"Growth hormone has been associated with growth of muscles and bones, and the production of it was believed to lie mainly in the pituitary
gland," said co-author Ken S. Kosik, co-director of the Neuroscience Research Center at the University of California, Santa Barbara. "No one had ...
The brain is broadly wired for reproduction
... of puberty, ovulation, and the menstrual cycle in females and testosterone production in males -- by regulating the release of hormones from the pituitary
gland. Interestingly, GnRH neurons also appear to be involved in the control of sexual behaviors.
"Consistent with the idea that GnRH neurons ...
Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress
... endocannabinoids on the synaptic circuits that control the activity of the hypothalamic neurons serve to rapidly inhibit hormone secretion from the pituitary
gland, providing a rapid negative feedback mechanism for the regulation of neuroendocrine function during stress."
Japanese team finds inhibition ...
A gene's first 'kiss' sets off that affair known as puberty
... reaction of chemical messages. Inside the hypothalamus, nerve cells release GnRH in a 'round-the-clock,' pulsatile fashion. With each secretion, the pituitary
gland is stimulated to secrete its own messengers, lutenizing hormone (LH) and follicle-stimulating hormone (FSH), directly into the circulation. In ...