Navigation Links
Phosphatase in Biological News

New insight into the mechanisms of voltage sensing and transduction in biological processes

... Bioscience, examine a voltage-sensitive phosphatase that converts an electrical to a chemical signal; ... were the major substrates of the phosphatase activity, and whether depolarisation or hyperpolarisation induced the phosphatase activity. By expressing phosphoinositide-specific ...

CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die

... transcription factor while, in other contexts, is also known to act as a phosphatase that is, it can remove phosphate groups from other proteins." The role of Eyes Absent in DNA damage repair EYA was shown to be a phosphatase by three separate groups in 2003. Although it was thought to be a PTP - ...

GUMC researchers find gene function 'lost' in melanoma and glioblastoma

... to cancer," Waldman says PTPRD produces a receptor protein tyrosine phosphatase that bisects the outer membrane of a cell. The part that protrudes outside ... yet in melanoma," Waldman says. "Before this study, no single tyrosine phosphatase was thought to play a generally important role as a tumor suppressor gene ...

Tumor suppressor gene in flies may provide insights for human brain tumors

... a counterpart in mammals, that can apparently prevent brain tumors from forming. "Our data explicitly show that the fruitfly protein PP2A (protein phosphatase 2A) suppresses brain tumor formation and controls the balance of self-renewal and differentiation of neural stem cells," said Hongyan Wang, Ph.D, ...

Key protein regulating inflammation may prove relevant to controlling sepsis

... the severe inflammatory condition caused by bacterial infection that afflicts many patients in intensive care units (ICU). In their paper, "WIP1 phosphatase is a negative regulator of NFκB signaling," published in the May 2009 issue of Nature Cell Biology (NCB), the IMCB scientists described their ...

Decreasing insulin resistance prevents obesity-related cardiovascular damage

... disease is the biggest health threat of obesity and Medical College of Georgia researchers trying to understand why have knocked out protein tyrosine phosphatase 1B, or PTP1B, in genetically fat mice that get diabetes. "Even before you have really bad diabetes, you are walking around obese with your glucose ...

Washington University scientists first to sequence genome of cancer patient

... novel mutations discovered, three were found in genes that normally act to suppress tumor growth. One of these mutations is in the PTPRT tyrosine phosphatase gene, which is frequently altered in colon cancer. Four other mutated genes appear to be involved in molecular pathways that promote cancer ....

SEX4, starch and phosphorylation

... across kingdoms. Amylopectin has similarities to glycogen, the soluble storage carbohydrate accumulated in animals, fungi, and bacteria. The SEX4 phosphatase is related to laforin, a protein involved in animal glycogen metabolism. When laforin is missing, insoluble starch-like polyglucosans (Lafora ...

Biophysical Society announces 2008 International Travel Awards

... Md. I. Hossain, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Japan, Voltage Range for Tuning of phosphatase of Ci-vsp as Measured by Two PIP2-Sensors. Naranamangalam R. Jagannathan, All India Institute of Medical Sciences, New Delhi, India, Role of ...

'Computer-chemistry' yields new insight into a puzzle of cell division

... the probable orientation required for a Cdc25B phosphatase enzyme to "dock" with and activate a ... sites" -- where chemical reactions occur --on the phosphatase and the kinase to link precisely, Rudolph said. ... residues the study identified, one residue on the phosphatase and the other on the kinase. Both hot spots are ...

Natural tumor suppressor in body discovered by UCSD medical researchers

... Located on chromosome 18 and called PH domain Leucine-rich repeat Protein phosphatase (PHLPP, pronounced "flip"), the tumor suppressor is described in the April ... Based on the chemical components of Akt, they specifically looked for a phosphatase linked to the PH domain, a protein module found in a wide variety of ...

UCSD researchers discover variants of natural tumor suppressor

... research by Newton's lab, also published in Molecular Cell, described the discovery of an enzyme they named PH domain Leucine-rich repeat Protein phosphatase (PHLPP, pronounced "flip") that turns off signaling of the Akt/protein kinase B, a protein which controls cell growth, proliferation and survival. ...

PTEN: the Treg's handbrake

... of Clinical Investigation, Laurence Turka and colleagues from the University of Pennsylvania have shown that Tregs from mice with T cells that lack phosphatase and tensin homolog (PTEN) proliferate in response to IL-2. Importantly, PTEN-deficient Tregs retained their suppressive function in vitro and in ...

Rutgers researchers find fat gene

... fat metabolism; they just didn't know how. The Carman team's first revelation came with the discovery that lipin is an enzyme (phosphatidic acid phosphatase or PAP), a protein catalyst that is required for the formation of fats ?triglycerides, specifically. The breakthrough for Carman's group grew out ...

Study uncovers placental microtransfusions lead to transmission of AIDS virus during childbirth

... medicine at the University of Melbourne. The study involved measuring -- in umbilical cord blood samples -- a protein known as placental alkaline phosphatase as an indicator of maternal-fetal microtransfusion. "This enzyme, made in the placenta, is very big -- usually too big to pass through the natural ...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

... that Akt inactivation by dopamine involves the formation of a previously unidentified complex containing beta-arrestin 2, Akt and a third protein phosphatase 2A that inactivates Akt. Mice lacking beta-arrestin become less responsive to certain drugs and exhibit abnormalities in behaviors, such as ...
Other Contents
(Date:8/25/2015)... BELLEVUE, Wash. , Aug. 25, 2015 ... systems, announced today it will unveil its "Guardian S" ... at the National Tactical Officers Association Conference on August ... Guardian S is the first-ever commercially available energetically autonomous ... research and in-field trials and is protected by more ...
(Date:8/20/2015)... , Aug. 20, 2015   Sensory, ... on improving the user experience and security of ... technologies, today announced that its TrulySecure™ ... authentication software to be FIDO Certified™. ... for compliance with the FIDO UAF (Universal Authentication ...
(Date:8/18/2015)... DUBLIN , Aug. 17, 2015 ... the addition of the "Global Biometric Authentication ... Application - Estimation & Forecast, 2015-2020" report ... biometric authentication and identification systems market is expected ... from 2015 to 2020 and generate over $25 ...
Breaking Biology News(10 mins):Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2
(Date:8/31/2015)... ... August 31, 2015 , ... CareSource, ... and Corporate Communications. In this capacity, Michael will provide strategic leadership for CareSource’s ... leader in consumer-focused programs that have contributed to the company’s rapid growth. As ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... In an ... from the Plastic and Reconstructive Surgery Global Open Journal that discusses the future of ... article discussed how, in the future, customized implants, prosthetics, and other 3-D printed tools ...
(Date:8/31/2015)... ... , ... NJ Top Docs Presents, Dr. Michael Betsy! Dr. Betsy has been reviewed and ... Michael Betsy graduated from Don Bosco Prep in 1990 and was Class Salutatorian. He ... sports in his senior year. He was inducted into the National Honor Society as ...
(Date:8/31/2015)... CA (PRWEB) , ... August 31, 2015 , ... According ... of the University of Sweden showed that most adolescents who underwent bariatric surgery “felt ... average, the 88 adolescent bariatric patients who participated in the study felt that their ...
(Date:8/31/2015)... ... August 31, 2015 , ... Dad Phil, son Scott, ... on Aug. 26, generously hosted by the Collinsville Chamber of Commerce, but the ... Call Center and website since Aug. 17. , The Greens have operated Green ...
Breaking Medicine News(10 mins):Health News:CareSource Names Vice President, Marketing and Corporate Communications 2Health News:Recent Article on 3-D Printing Highlights the Future of Custom Medical Solutions Using the Technology, says Beverly Hills Physicians 2Health News:Recent Article on 3-D Printing Highlights the Future of Custom Medical Solutions Using the Technology, says Beverly Hills Physicians 3Health News:NJ Top Docs Presents, Dr. Michael Betsy! 2Health News:NJ Top Docs Presents, Dr. Michael Betsy! 3Health News:Article on Adolescent Bariatric Surgery Demonstrates the Powerful Effect of Being in Control, Notes Dr. Michael Feiz 2Health News:Article on Adolescent Bariatric Surgery Demonstrates the Powerful Effect of Being in Control, Notes Dr. Michael Feiz 3Health News:Ribbon Cutting Launches AdvantaClean of Madison County 2
Other TagsOther Tags