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Peroxisome in Biological News

Pulmonary hypertension in children may result from reduced activity of gene regulator

... In a surgically created animal model of a congenital heart defect that causes too much pulmonary blood flow, they have already shown PPARs peroxisome proliferator-activated receptors are down regulated. In these lambs, whose four-chambered hearts are essentially identical to humans, agonists to ...

Resveratrol prevents fat accumulation in livers of 'alcoholic' mice

... found that the increased expression of SIRT1 and AMPK led to: Reduction of sterol regulatory element binding protein (SREBP-1) Activation of peroxisome proliferator-activated receptor gamma co-activator alpha (PGC-1α) Elevation of circulating adiponectin, a hormone produced by fat cells, which ...

Biologists at UC San Diego identify key protein in cell's 'self-eating' function

... understand how and why they are selected by the lysosome for degradation. What the biologists found, he said, is that this new protein can mediate peroxisome selection during pexophagy that is, it is necessary for pexophagy, but not for other autophagy-related processes. Suresh Subramani, a professor ...

Hormone helps mice 'hibernate,' survive starvation

... at play during starvation and fasting. They focused on a nuclear receptor – a protein that turns genes on and off in the body – called peroxisome proliferator-activated receptor alpha, or PPAR-alpha, which is known to control the use of fat as energy. Starving mice without PPAR-alpha become ...

Fat screen delivers plant-derived chemical with antidiabetic effects

... or TZDs, work through a counterintuitive mechanism: they restore insulin sensitivity by activating a central promoter of fat tissue production called peroxisome proliferator-activated receptor ã (PPARã). "The current explanation for this paradoxical mode of action is the idea that the body needs a place ...

Gut research yields new anti-cancer approach

... a new way to fight colorectal cancer, and potentially cancers of the esophagus, liver and skin. Early work shows that a group of compounds called peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibitors may have an unexpected cancer-fighting effect, according to research published today in ...

New understanding of parasite cell structures may provide treatments for serious tropical diseases

... The new research will open areas for further investigation. "Before this work in trypanosomes, there was no evidence that we could 'catch' peroxisome proteins moving to the ER" said Mensa-Wilmot. "With better understanding of the process we could begin looking for compounds that may act as drugs by ...

Opposing fat metabolism pathways triggered by a single gene

... expression of another gene fat-7, which, by reducing acs-2, increases fat content. In its function, nhr-49 resembles a mammalian NHR, called peroxisome proliferator-activated receptors (PPARs). Further investigation of this link may lead to better understanding of the functions of PPARs and provide ...
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(Date:7/22/2014)... promise for treating damaged organs and tissues, but with ... their effectiveness. New methods are being developed and tested ... after transplantation, as described in a Review article in ... Mary Ann Liebert, Inc., publishers. The article is available ... website . , In the article ,Preconditioning ...
(Date:7/22/2014)... Cambridge, MA and Shenzhen, China July 22, ... Tech), a subsidiary of BGI, the world,s largest ... a new human whole exome sequencing service based ... service includes in-depth bioinformatics analysis and SNP validation, ... 31, 2014. , Complete Genomics, highly regarded ...
(Date:7/22/2014)... a place emerging as a world-famous vacation spot with natural ... on the island. The Korea Institute of Geoscience and Mineral ... that a recent volcanic eruption was evident 5,000 years ago. ... date when lava spewed out of a volcano 5,000 years ... as the one the whole peninsula. , The research team ...
Breaking Biology News(10 mins):BGI Tech launches human whole exome sequencing service on complete genomics' advanced platform 2Jeju Island is a live volcano 2
(Date:7/22/2014)... undergoing a minimally invasive hysterectomy using electric power morcellation, ... at the time of the procedure, according to a ... concern that this procedure, in which the uterus is ... of undetected malignancies. , Despite the commercial availability of ... the prevalence of malignancy at the time of electric ...
(Date:7/22/2014)... Marc, Ph.D., director of research at the University of ... by the International Society of Eye Research (ISER) as ... 2014 Paul Kayser International Award in Retina Research., The ... has made a significant contribution to the understanding of ... this week at the ISER Biennial Meeting in San ...
(Date:7/22/2014)... -- The American Society of Hematology (ASH) will present ... Award for Lifetime Achievement in Hematology, to Kanti R. ... (LIJ) School of Medicine for his 50-year career combining ... mentoring, and exceptional patient care. , The Wallace ... bestowed on an individual who has been a vital ...
(Date:7/22/2014)... As reported on July 17, 2014 by ... name her favorite beauty products, “ Botox , that’s pretty ... “ Botox has changed my life” by halving the ... for her various, daily appearances. “Suddenly my eyelids are ... goo.gl/shmTQM). , “I think that Kelly Ripa’s response to the ...
(Date:7/22/2014)... Autoimmune disorders may share certain pathogenic mechanisms with cancer, ... (GW) researcher Linda Kusner, Ph.D. , published in ... paradigm shifting work shows that the very same inhibitors ... expressed in cells that produce autoimmune diseases. Henry ... at the GW School of Medicine and Health Sciences ...
Breaking Medicine News(10 mins):Health News:Study examines presence of uterine cancers at the time of hysterectomy using morcellation 2Health News:University of Utah researcher Robert Marc receives Paul Kayser International Award 2Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 2Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 3Health News:ASH honors Kanti R. Rai, M.D., with Coulter Award for Lifetime Achievement 4Health News:Celebrity Botox: Kelly Ripa Confesses to Getting Botox Injections 2Health News:New research finds pathogenic connection between autoimmune disorders and cancer 2
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