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Ovarian in Biological News

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this ... for Cancer Research. Although early stage ovarian cancer can be treated with a combination of ...

2 reproductive factors are important predictors of death from ovarian cancer

... (CDC) found that survival among women with ovarian cancer is influenced by age of menarche and total ... lifetime may influence the prognosis after an ovarian cancer diagnosis. Results of this study are ... on a patient's survival after a diagnosis of ovarian cancer. Cheryl L. Robbins, Ph.D., an ...

Ovarian transplantation: First baby is born after a new technique

... France, described a new, two-step method of ovarian transplant that has produced excellent results in ... said that his team's technique worked to restore ovarian function quickly and already one patient from his ... sickle cell anaemia. After transplanting her own ovarian tissue she started ovulating in four months and ...

Ovarian transplantation: New technique gives greatly improved results in this delicate operation

... The Netherlands: Ultra-fast freezing of ovarian tissue from women who have lost their fertility ... or preservation of oocytes in fresh and frozen ovarian tissue of 15 young women undergoing cancer ... fresh ovary transplantation for the duration of ovarian function and pregnancy outcome, and tested spare ...

Genetic testing for breast or ovarian cancer risk may be greatly underutilized

... increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, ... cancer is about 13 percent, and the risk for ovarian cancer is less than 2 percent. But women with ... cancer and 9 to 30 times more likely to develop ovarian cancer than women with unaltered forms of the ...

Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells

... This approach was originally developed in ovarian cancer cells by study co-author Janet Sawicki, ... group had recent success in reducing the size of ovarian tumors following treatment with diphtheria toxin ... The strategy is based on the fact that both ovarian and pancreatic cancer cells significantly ...

Promising new treatment option for women with recurrent ovarian cancer

... provides clinical benefit to women with relapsed ovarian cancer, according to new results presented at the ... an important new option for women with recurrent ovarian cancer." Trabectedin, a synthetic version of a ... studied the combination in 672 women whose ovarian cancer had progressed after first-line therapy. ...

Cryopreservation techniques bring hopes for women cancer victims and endangered species

... fertility for women after diseases such as ovarian cancer that lead to destruction of reproductive ... endangered animal species by maintaining banks of ovarian tissue or even nascent embryos that can used to ... concerning preservation of animal and human ovarian tissue have been largely separate, but are now ...

TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer

... of tissue type transglutaminase (TG2) in ovarian cancer is associated with increased tumor cell ... a novel therapeutic approach for late-stage ovarian cancer. These findings in the July 15th issue ... among the first to explore TG2's functionality in ovarian cancer. "TG2 appears to fuel different types ...

Oocyte-specific gene mutations cause premature ovarian failure

... Mutations in a gene called FIGLA cause premature ovarian failure in at least a percentage of women who ... at BCM and senior author of the paper. Premature ovarian failure, which means that the ovaries lose ... it with infertility, women with premature ovarian failure face an increased risk of cardiovascular ...

Pregnancy is possible after cancer treatment

... for the first time in Germany that healthy ovarian tissue has been taken from a non-pregnant woman ... Erlangen physicians succeeded in removing healthy ovarian tissue from the woman before treatment and to ... years. For this reason, the patient's conserved ovarian material was inserted endoscopically into her ...

Ovarian cancer stem cells identified, characterized

... have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancers recurrence and its resistance to ... effective and targeted treatment for epithelial ovarian cancer, one of the most lethal forms of cancer, ...

Continuous oral contraceptives better at easing pain, bleeding

... several medical conditions, where continuous ovarian suppression is desired, such as acne, hirsutism, ... But there have been few detailed studies of ovarian function on the pill to demonstrate this ... monitored vaginal bleeding, quality of life, and ovarian and endometrial suppression," said Legro, whose ...

Varying prevalence among ethnic groups of gene mutation that increases risk of breast cancer

... gene BRCA1 confer high risks of breast and ovarian cancer. Average cumulative risk by age 70 years ... 65 percent for breast cancer and 39 percent for ovarian cancer, according to background information in ... with multiple relatives having breast or ovarian cancer, early-onset breast cancer, or of ...

Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer

... COX2 gene seems to play a role in the onset of ovarian cancer, increasing womens susceptibility to ... are used already for other conditions, to prevent ovarian cancer developing in women with the COX2 ... physiological processes. Although the causes of ovarian cancer are not fully understood yet, inflammation ...

American Chemical Society's Weekly PressPac -- Aug. 15, 2007

... Cranberries may improve chemotherapy for ovarian cancer Source of coffees bitterness ... Time Cranberries may improve chemotherapy for ovarian cancer Compounds in cranberries may help ... drugs that are used in chemotherapy to fight ovarian cancer, researchers have found in a laboratory ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

... PHILADELPHIA Many women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to ... of BRCA1 and BRCA2 gene mutations to reduce the risk for breast and ovarian cancer. Evaluated by gene type, bilateral risk-reducing ...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

... physical activity has been shown to decrease lifetime exposure to ovarian hormones in women and has been found to play a protective role against breast cancer. However reduction in ovarian hormone exposure has been associated with increased risk of cognitive ...

Association for Molecular Pathology joins ACLU to challenge gene patents

... charging that patents on two human genes associated with breast and ovarian cancer are unconstitutional and should be invalidated. Individuals with ... are at a significantly higher risk for developing hereditary breast and ovarian cancers. The lawsuit, Association for Molecular Pathology, et al. v. ....

2009 Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research

... Fred Hutchinson Cancer Research Center, Seattle: for Early Detection of ovarian and Lung Cancers For many years, scientists have unsuccessfully ... the development of a highly sensitive blood test for cancers, particularly ovarian and lung, both of which are notoriously difficult to detect in their ...

Birth control has long-term effect on hormone exposure

... why past oral contraceptive use dramatically lowers the risk of ovarian and uterine cancers later in life. While studying the effect of ... years that past oral contraceptive use significantly lowers the risk of ovarian and uterine cancers later in life, this new observation in monkeys may ...

Chemical compound prevents cancer in lab

... treatment with Flex-Hets are polycystic kidney disease, kidney cancer and ovarian cancer. Benbrook and her research team have patented the Flex-Het ... treatments, especially in cancers that are caught in later stages such as ovarian cancer where life expectancy can be as short as 6 months after treatment. ...

Glypican-3 gene function in regulating body size helps inform novel cancer treatments

... for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3 (GPC3), ... overgrowth activity to benefit SGBS patients and the many breast, lung and ovarian cancer patients linked to loss of GPC3, says Dr. Jorge Filmus, senior ...

The surprising power of the pill

... a period, allows the treatment to be adjusted without compromising the ovarian response to stimulation, says Dr. Pinkas. This way, egg-harvesting can ... unique in that it placed an emphasis on the impact of a patients age, her ovarian response, the characteristics of her cycle, and the final outcome a ....

Should children be permitted to get genetic testing for BRCA 1/2 mutations?

... for gene mutations that predispose them to developing breast cancer and/or ovarian cancer later in life" New research suggests the next generation of ... with an alteration are at an increased risk of developing breast and/or ovarian cancer. Risk reduction options such as prophylactic surgeries, heightened ...

Last chance for media to register for ECCO 14 -- the European Cancer Conference

... discover a specific genetic mutation can double or treble a womans risk of ovarian cancer Researchers discover PET is more useful than mammography or ... study fuels debate over whether body size and exercise influence ovarian cancer risk Chemotherapy drug delays progression of operable ...

MIT works toward safer gene therapy

... if needed, said Green. One promising line of research involves ovarian cancer, where the MIT researchers, in conjunction with Janet Sawicki at ... that these polymer-DNA nanoparticles can deliver DNA at high levels to ovarian tumors without harming healthy tissue. ...

Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA

... Approximately 20 percent of women with the premutation have premature ovarian failure a loss of ovarian function in women younger than 40. Lead authors of the current study ...

Pitt researchers find promising candidate protein for cancer prevention vaccines

... work, we found that women who developed an immune response to MUC1, typically after pelvic surgery, mumps or mastitis, have a much lower risk for ovarian cancer," Dr. Finn said. "Cyclin B1 and MUC1 are part of a big family of self-proteins that become over-produced during cancer development, so they ...

2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award

... Program. Prior to joining the Hutchinson Center faculty in 2004, she worked at the National Cancer Institute on the Prostate, Lung, Colorectal and ovarian Cancer Screening Trial. This experience provided Peters with a wealth of collaborative projects, giving her broad-based experience in nutritional and ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

... a significantly higher risk of death than did other patients, ranging from 21 percent higher for those with prostate cancer to 61 percent higher for ovarian cancer patients. The poorer outcome for African-American cancer patients was supported by separate data published last month in the Journal of ...

UC Davis begins $2.8 million in studies of agricultural nitrogen's impacts

... common cold; High concentrations of nitrates in groundwater, which can cause methemoglobinemia, or "blue baby disease," and possibly bladder and ovarian cancers; and Nitrogen runoff in bays and coastal areas, where it makes algae numbers spike then crash, drawing oxygen from the water and leading ...

Cancer: The cost of being smarter than chimps?

... rates of cancer? That's a question that has nagged at John McDonald, chair of Georgia Tech's School of Biology and chief research scientist at the ovarian Cancer Institute, for a while. Now, after an initial study, it seems that McDonald is on to something. The new study is available online in the ...

Common chemotherapy drug triggers fatal allergic reactions

... the U.S., Europe and Japan. The most common cancer diagnosis for these patients with allergic reactions was lung cancer followed by breast cancer and ovarian cancer. ...

Stem cell protein offers a new cancer target

... that LIN28 can transform cells to a cancerous state, and that it is abundant in a variety of advanced human cancers, particularly liver cancer, ovarian cancer, chronic myeloid leukemia, germ cell tumors and Wilm's tumor (a childhood kidney cancer). They believe that overall, LIN28 and a related ...

NAU discovery could help feed millions

... sterilization technology derived from Mayer's research, done by Patricia Hoyer and and Glenn Sipes at UofA, investigated potential damage caused to ovarian follicles in women exposed to certain chemicals in industrial settings. Of particular interest was a chemical compound known as 4-vinylcyclohexene ...

ACLU -- Myriad Genetics lawsuit will become landmark case

... Genetic Engineering & Biotechnology News (GEN). ( www.genengnews.com ) The ACLU charged that the patenting of two human genes linked to breast and ovarian cancer will inhibit medical research. The organization also claims that the patents are invalid and unconstitutional. "This is going to turn into ...

Breast health center gives TGen new research opportunities

... diagnostic tests and smarter treatment options for newly-diagnosed breast cancer patients,'' said Dr. Heather Cunliffe, head of TGen's Breast & ovarian Cancer Research Unit. The new center is located in John C. Lincoln's Medical Offices 3, 19646 N. 27th Ave., just southwest of Interstate 17 and ...

UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs

... his findings could have relevance to other cancers that show aggressive properties. For example, Muc4 is also expressed in pancreatic, lung and ovarian tumor cells. "Muc4 is likely a central cellular mechanism for metastasis of many cancers, and we will be continuing this important work to prove ...

AIUM presents 2009 William J. Fry Memorial Lecture award

... course. Dr Kurtz has been involved in 8 grants, including one as principal investigator of a multicenter study on the diagnosis and staging of ovarian cancer, awarded by the National Cancer Institute of the National Institutes of Health. The recipient of the AIUM William J. Fry Memorial Lecture ...
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