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Mutational in Biological News

SEX4, starch and phosphorylation

... well understood. With new information emerging from genome sequencing and mutational analyses, we are beginning to gain a better understanding of these complex ... Society of Plant Biologists in Mrida, Mexico (June 27, 2:30 PM). mutational and structural analyses by Dr. Zeeman and his colleagues have revealed ...

UCSB researchers discover the dawn of animal vision

... only a handful of cases where scientists have documented the very specific mutational events that have given rise to new features during evolution. Oakley ... that such claims are simply wrong. We show very clearly that specific mutational changes in a particular duplicated gene (opsin) allowed the new genes to ...

Two new studies on circadian rhythms

... proteins to track and correlate changes in the core circadian network. They determined the clusters and locations of known sites, and through mutational analysis identified novel functional domains to create a dynamic view of a clock protein in action. ...

Cystic fibrosis testing -- next steps

... how the widespread and thoughtful experience with [cystic fibrosis] mutation testing and screening continues to reveal new insights about the mutational alleles of the CFTR gene and further refinements in how best to detect them and assure appropriate quality control while doing so." ...

Evolution follows few of the possible paths to antibiotic resistance

... evolution follows very few of the available mutational pathways to attain fitter proteins, researchers ... work indicates that of 120 harrowing, five-step mutational paths that theoretically could grant antibiotic ... property of DNA is that very many distinct mutational paths link any two variants of a gene," says lead ...

Harmless virus may hold key to more effective HIV drug discovery

... the bacteriophage can model millions of different mutational variants of an HIV protein called Nef. Knowing ... was then coaxed into synthesizing the millions of mutational variants of Nef. The researchers then targeted ... that could target the entire population of Nef mutational variants. The results suggest chemically simpler, ...

Key brain regulatory gene shows evolution in humans

... baboons, pig-tailed macaques and rhesus monkeys. They found significant mutational changes in the regulatory sequence leading to humans that indicated ... in which sequences near the regulatory segment showed greater mutational change -- as if they were "dragged along" with the evolving regulatory ...

Scientists discover a genetic code for organizing DNA within the nucleus

... humans. Several diseases, such as cancer, are typically accompanied or caused by mutations in the DNA and the way it organizes into chromosomes. Such mutational processes may be influenced by the relative accessibility of the DNA to various proteins and by the organization of the DNA in the cell nucleus. ...

Researchers identify genes in fruitflies that may shed light on human cancer spread

... Whole genome studies, like the microarray analysis used in this study, allow researchers to identify genes that share similar functions in a way that mutational analysis cannot. And, whole genome approaches can look at most of the genes in the genome at one time. As part of their previous work, Montell's ...

Housecat-sized Siberian tiger cubs get collared

... in prostate cancer susceptibility. "Because of the strong similarity among genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in ...

Studies on human genome variation provide insight into disease

... in prostate cancer susceptibility. "Because of the strong similarity among genes in this region, we had to develop a new technique for our mutational analysis, which we call TAR cloning," explains Larionov. "Using this method, we isolated the SPANX region from 200 individuals by recombination in ...
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