UC Davis researchers discover how HIV turns food-poisoning into lethal infection
... HIV. In a 2006 study, she found that HIV continued to replicate in the gut mucosa
and suppress immune function in patients being treated with antiretroviral ... between an individuals immune system and HIV is happening in the gut mucosa
where there is massive destruction of immune cells, Dandekar said. ...
Skin-like tissue developed from human embryonic stem cells
... Tufts have harnessed the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues that mimic human skin and the oral mucosa
(the moist tissue that lines the inside of the mouth). The proof-of-concept study is published online in advance of print in Tissue Engineering Part ...
Nanotechnology holds promise for STD drug delivery
... found that the particles, loaded with the drug agent, moved effectively in two important ways, penetrating to reach cells below the surface of the mucosa
and distributing throughout the vaginal, cervical, and uterine regions. Furthermore, the siRNAs stayed in the tissues for at least a week and ...
Human Microbiome Project awards funds for technology development, data analysis and ethical research
... Vincent Young, M.D., Ph.D., University of Michigan, Ann Arbor; $1.3 million (3 years); Cultivation and Characterization of the Microaerobes from the mucosa
of the Gastrointestinal Tract.
Kun Zhang, Ph.D. and Yu-Hwa Lo, Ph.D., University of California, San Diego; $1.8 million (3 years); An Integrated ...
Breakthrough optical technology to assess colon cancer risk, accuracy
... was elevated 75.3 percent above control levels (comparable region from patients with no adenomas) at the adenoma site and persisted in the uninvolved mucosa
(microscopically normal) area. Moreover, tissue sites located within 10 and 30 centimeters away from an adenoma also manifested a highly ...
Change in gene may be underlying molecular defect in some colorectal cancers
... in the tumor, adjacent mucosa, and nonadjacent mucosa
of 95 colorectal cancer patients and in the colon mucosa
of 33 subjects without cancer.
MGMT promoter ... method of detection, and normal-appearing colon mucosa
up to 10 cm away from the tumor had detectable ...
Anti-herpes treatment reduces HIV levels in women infected with both viruses
... HSV-2 enhances the risk of HIV-1 acquisition by around three-fold2. HSV-2 infection may also increase HIV-1 infectiousness by disrupting the genital mucosa
and increasing the levels of HIV in the genital tract3, allowing easier transmissibility of the virus. In addition, the HIV viral load in the blood ...
Stomach receptor for H. pylori discovered
... to peptic ulcer disease, gastric adenocarcinoma, and non-Hodgkins lymphoma of the stomach.
"Ulcers are a breach in the gastric or duodenal mucosa
and gastric adenocarcinoma is one type of cancer of the stomach," explains senior author Dr. Richard M. Peek, Jr. of the Vanderbilt University School ...
Pregnant women at higher risk for HIV, Uganda study finds
... is unlikely that the change in HIV risk we observed is due to sexual behaviors. It may be attributed to hormonal changes affecting the genital tract mucosa
or immune responses," said Gray. ...
Asthma gene clusters identified
... genes involved in childhood asthma, she said.
This study exclusively focused on genes associated with epithelial cells. Genes associated with mucosa
and underlying cells are likely to be involved as well.
Dr. Hershey is expanding her research in cooperation with the Computational Medicine ...