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Molecule in Biological News

Nanophysics: Serving up Buckyballs on a silver platter

... and chemists alike. Like a soccer ball, the molecule consists of 20 carbon hexagons and 12 carbon ... To do this, researchers need to know how the molecule forms bonds with a metal substrate, such as ... way namely, by forming a 'hole' beneath each C60 molecule - that reinforces the bonding between the carbon ...

Protein can help cells or cause cancer, Purdue researcher finds

... overabundance of the polo-like kinase 1, or Plk1, molecule during cell growth, as well as a shortage of the ... Studies in Liu's laboratory showed that the Plk1 molecule indirectly attacks p53 in a process called ... affected. Liu said it is unknown why the Plk1 molecule chooses to initiate ubiquitination over ...

GUMC discovery highlights new direction for drug discovery

... discovering and successfully testing a small molecule that keeps the fusion protein from sticking to ... shape constantly. "Most targeted small molecule cancer drugs inhibit the intrinsic activity of a ... stuck to another protein, RNA helicase A (RHA), a molecule that forms protein complexes in order to control ...

Rampant helper syndrome

... cofactor known as F0 or F420 which is the tiny molecule deazaflavin. It has previously been found only in ... and has accordingly been considered the signature molecule for those species. A research group working with ... Enzymatic methane production involves the tiny molecule deazaflavin, known as cofactor F0 or cofactor ...

New trigger for chronic inflammation in rheumatoid arthritis discovered

... A signal molecule made by the human body that triggers the immune ... from disease. Today's findings show that a signal molecule called tenascin-C can trigger the same molecular ... injected the active part of the tenascin-C molecule into mice joints. They found it caused the joints ...

Toxic molecule may help birds 'see' north and south

... at the University of Illinois report that a toxic molecule known to damage cells and cause disease may also ... the reaction partner is not the benign oxygen molecule that we all breathe, but its close cousin, ... said. But this gives an advantage, since the molecule must be present at low concentrations but not ...

Scientists develop a new HIV microbicide -- and a way to mass produce it in plants

... antibody and cyanovirin-N) into a single "fusion" molecule and showed that this molecule is more active against HIV than either of its ... They designed synthetic DNA for producing this molecule and introduced this DNA into plant cells. After ...

International team tracks clues to HIV

... company taking a shotgun approach -- make a molecule and try it out, then make another molecule and try it out," said Barron, Rice's Charles W. ... was to find an existing fullerene derivative molecule that could be easily modified to become the ...

Researchers find snippet of RNA that helps make individuals remarkably alike

... researchers now have identified a type of molecule that plays a specific role in maintaining ... cells of the body work together in networks, each molecule interconnected with others. "When something is changed, say the genetic sequence of a molecule or the temperature of the organism, the network ...

Brain protein central to both Parkinson's, drug addiction identified

... dopamine neurons. That's where another molecule known as the dopamine transporter picks it up and ... have a higher potential for addiction. The molecule might also offer a new target for treating ... its effects in a condition where it makes a toxic molecule available to vulnerable cells, as illustrated in ...

UT Southwestern researchers probe kidney damage, protection in lupus

... "In addition, they highlight a certain molecule as a potential target for treating this disease," ... cells in those mice overproduced a particular molecule called CXCR4. In fact, the mice had up to twice ... might be causing the kidney damage. The CXCR4 molecule was already known to play a role in creating ...

Genetic switch potential key to new class of antibiotics

... controls the ability of bacteria to produce a molecule called queuosine. In many organisms, queuosine or ... The binding of the aptamer to the signaling molecule changes the platform's shape. Oftentimes, the ... have to bind in place of the natural signaling molecule (e.g. preQ0), and lock the mRNA into a stable ...

A miR boost enables acute leukemia cells to mature

... researchers shows that boosting the level of a molecule called miR-29b in acute myeloid leukemia (AML) ... be a potent treatment for AML. The molecule blocks the action of three enzymes, all of which ... and provides a rationale for developing this molecule as a possible drug for the treatment of AML, ...

International prize for Nottingham spine research

... and injected them with a dye containing the molecule gadolinium, which is roughly the same size as a drug molecule and has magnetic properties enabling them to ... body using an MRI scanner. They found that the molecule moved across the discs in two ways; by diffusion ...

Dancing 'adatoms' help chemists understand how water molecules split

... with the help of water molecules. If a water molecule sits down next to an adatom, one of the water's ... turning back into a water molecule. The water molecule floats off, leaving behind an adatom. Half the ... help the adatom jump a row as well: If a water molecule and an adatom are situated on either side of a ...

Researchers identify new way the malaria parasite and red blood cells interact

... it. For decades, researchers have known that a molecule called glycophorin B, which is found on the ... of the malaria parasite. However, the specific molecule by which the malaria parasite attaches itself to ... each other. The findings revealed that the EBL-1 molecule is the specific attachment site used by the ...

New models question old assumptions about how many molecules it takes to control cell division

... physics." The weak link in the is mRNA: the molecule that carries information from the gene to the ... reports that there is on average only 1 mRNA molecule per gene per cell, in yeast, and that each mRNA molecule lives, on average, for 15 to 20 minutes before it ...

UT Southwestern researchers identify molecule that helps the sleep-deprived to mentally rebound

... Working with mice, they found that a molecule called an adenosine receptor is necessary for ... brain cells, are akin to docking points for the molecule adenosine. Adenosine levels increase in the brain ... hour of waking activity, and "docking" of the molecule with its receptor is shown in this study to help ...

Canadian scientist mines drugs database for new diabetes treatment

... have used this new method to identify a small molecule which they are using to understand how insulin is ... their method by successfully identifying a small molecule called Ned-19. This molecule was found after information about the natural ...

Scientists mine drugs database for new diabetes treatment

... have used this new method to identify a small molecule which they are using to understand how insulin is ... their method by successfully identifying a small molecule called Ned-19. This molecule was found after information about the natural ...

In India: A search for more effective tuberculosis drugs

... tuberculosis in its tracks. In a test tube, the molecule hits four of the bacterium's crucial metabolic ... Gokhale's group shows how they designed the molecule that targets multiple enzymes in Mycobacterium ... stages disease," Gokhale said. "Since this single molecule could potentially grind the assembly line to a ...

The quest for specific anti-inflammatory treatment

... of the C1P (ceramide-1-phosphate) molecule. This molecule was discovered in 1990 in a case of human ... apparently contradictory, in some cells this same molecule functions in an anti-inflammatory manner. With ... the anti-inflammatory abilities of the C1P molecule one team in Virginia (USA), the pharmaceutical ...

Study links molecule to muscle maturation, muscle cancer

... Cancer Center have discovered that a molecule implicated in leukemia and lung cancer is also ... called miR-29, to become mature, and that the molecule is nearly missing in cells from rhabdomyosarcoma, ... rhabdomyosarcoma tumors showed levels of the molecule that were 10 percent or less of those in normal ...

Tips from the American Journal of Pathology

... have explored the expression of an immune molecule (CXCL1) that interacts with myelin-producing ... and have been shown to respond to the immune molecule CXCL1, although the role of CXCL1 in MS has not ... State University have identified a potential new molecule that inhibits inflammation, receptor for ...

UC Davis researchers find molecule that targets brain tumors

... researchers report today the discovery of a molecule that targets glioblastoma, a highly deadly form ... Lam and his colleagues began searching for a molecule that could be injected into a patient's ... tissues. Through their study, they identified a molecule called LXY1 that binds with high specificity to ...

TGen, Scottsdale Healthcare, Mayo Clinic study new drug to stimulate immune system of cancer victims

... promising. "VTX-2337 is a new, novel, small molecule aimed at stimulating the immune cells in the ... into a clinical development company with a novel molecule that may play an important role and have broad ... the treatment of cancer." VTX-2337 is a small molecule TLR8 agonist that is expected to be used in ...

Water in the early universe

... interval to stretch the line emission of the H2O molecule from its original frequency of 22 GHz to 6 GHz ... John McKean. "This suggests that the water molecule may have been much more abundant in the early ... and shows that the conditions for the water molecule to form and survive already existed only 2.5 ...

Properties of unusual virus revealed in research

... The picture of this RNA polymerase and DNA molecule has enabled the team to investigate how the RNA ... As expected, the high temperatures caused the molecule to unfold. The scientists then cooled the molecule and watched as it reformed into its original ...

The Burnham buzz

... muscle cells. By inhibiting HDAC2 with small molecule compounds or RNA interference, Dr. Lorenzo was ... have determined that a biologically active molecule called a chemokine promotes the spread of tumors, ... Dr. Ronai's team is now investigating how small molecule compounds might accomplish the same thing. ...

Researchers study virus with unusual properties

... The picture of this RNA polymerase and DNA molecule has enabled the team to investigate how the RNA ... As expected, the high temperatures caused the molecule to unfold. The scientists then cooled the molecule and watched as it reformed into its original ...

Simple chemical procedure augments therapeutic potential of stem cells

... target. To do this, they simply added a molecule called SLeX to the surface of the cells. The ... could correct this problem by adding a particular molecule to the surface of adult stem cells. This ... Sarkar tweaked the concentrations of each molecule to maximize the cell's ability to roll along the ...

Waste from gut bacteria helps host control weight, UT Southwestern researchers report

... DALLAS Oct. 17, 2008 A single molecule in the intestinal wall, activated by the waste ... found in a mouse study. When activated, the molecule slows the movement of food through the intestine, ... "It's quite possible that blocking this receptor molecule in the intestine might fight a certain kind of ...

Scientists from Granada find a potential treatment to prevent diabetes and obesity

... is available in French and Spanish . A molecule called interleukin-6 has opened new doors for the ... Journal of Endocrinology. An (un)known molecule The main discovery has been the change of the paradigm of a molecule called interleukin-6 in the prevention of obesity ...

Gold nanostars outshine the competition

... solution containing the nanoparticles and the molecule of interest and monitor the scattered light. The detailed characteristics of both the molecule and the nanoparticle affect the strength of ... which contains an identifying fingerprint for the molecule known as its vibrational signature. With ...

Researchers identify promising gene target for neuroblastoma therapy

... is intriguing because a small "targeted" molecule inhibitor caused neuroblastoma cell lines ... investigators mixed a powerful ALK-blocking molecule into batches of test cells whose ALK receptors ... each of the newly discovered mutations. The small molecule inhibitor, TAE684, halted proliferation and ...

Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

... to bright light. The section of the enzyme molecule that most interests the researchers is the ... enzyme. "The domain binds to this small molecule with extremely high sensitivity," said UW ... in recognizing and responding to the messenger molecule to create an instantaneous flow of information to ...

Cross kingdom conflicts on a beetle's back

... In addition, they've identified the specific molecule that drives this whole phenomenon. The ... techniques and chromatography, to both locate the molecule and identify its structure. The molecule turns out to be a kind of fatty acid. "It's ...

Scientists identify novel inhibitor of human microRNA

... colleagues have identified, for the first time, a molecule that can regulate microRNAs short strands of RNA ... drugs. The research team identified a small molecule that blocks the pathway of a particular miRNA, ... and ovarian cancer. With further development, the molecule has the potential to boost patient response to ...

Simulations help explain fast water transport in nanotubes

... resulting in no transport. Water is a polar molecule consisting of two hydrogen atoms and one oxygen atom. Although its net charge is zero, the molecule has a positive side (hydrogen) and a negative side (oxygen). This polarity causes the molecule to orient in a particular direction when in the ...

New beta-blocker to offer hope to heart and lung sufferers

... Nottingham scientists have already developed a molecule that is much more effective at discriminating ... them to carry out further studies to improve the molecule to ensure that it is able to target the heart ... Biomedical Sciences said: "Once developed, this molecule will cause much less wheezing and shortness of ...
Other Contents
(Date:7/11/2014)... two different ways that allow unprecedented experimental insights ... of oxygen molecules in photosynthesis. The two studies ... Nature Communications . , "The new knowledge will ... oxidation, which are key components for building artificial ... energy in fuels like hydrogen, ethanol or methanol," ...
(Date:7/11/2014)... that transplantation of mesenchymal stem cells can stimulate neurogenesis ... of Alzheimer,s disease (AD) and improve tissue and function ... are reported on the therapeutic effect of adipose-derived stem ... the effect on oxidative injury and neurogenesis in the ... team, School of Life Sciences, Tsinghua University, China transplanted ...
(Date:7/11/2014)... Evidence exists that cannabinoid receptor type 1 ... Ca2+ influx, and reduce neurotransmitter release. However, ... 1 can increase extracellular Ca2+ influx and ... his team, Tongji Hospital Affiliated to Tongji ... Technology, China used whole cell voltage-clamp and ...
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(Date:7/11/2014)... 2014 As reported by the ... 7/11/14), a significant number of severe adverse events such ... and even death from the highly-promoted and costly immune-system ... Times report , a regulatory filing revealed that ... patients was almost 14% of prescriptions, up from 9.1% ...
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