Protein handlers should be effective treatment target for cancer and Alzheimer's
... 12 months to support studies of proteins and the molecular
chaperones that manage them from cradle to grave.
Understanding the exact role molecular
chaperones play in cancer and Alzheimer's should ... says Dr. Mivechi, director of the MCG Center for molecular
Chaperone Biology/Radiobiology and Cancer ...
Stunting plants' skyward reach could lead to improved yields
... An assistant professor of biochemistry and molecular
biology with the Plant Research Laboratory at ... explained, making it hard to nail down at the molecular
level exactly what causes a specific effect in a ... chairman of the Department of Biochemistry and molecular
Biology. "This is a very significant grant from ...
SRI announces selection by the National Cancer Institute as a Chemical Biology Consortium center
... new cancer therapeutics active against novel molecular
and genetic cancer targets. Based on its track ... the discovery of compounds active against novel molecular
and genetic cancer targets.
Sambucetti will ... drug discovery. These tools employ novel molecular
descriptors that are derived from active ...
The right messenger for a healthy immune response
... Researchers from the molecular
Immunology group at the Helmholtz Centre for ... immune system," says Siegfried Wei, leader of the molecular
Immunology group at the HZI. His research ... is doing in immune cells. She found a molecular
factor that is pivotal in producing the ...
22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey
... brains biochemical circuitry and breakthroughs in molecular
genetics have significantly enhanced the ... involved in mental disorders. Breakthroughs in molecular
genetics shed light on hereditary diseases, i.e. ... to researchers in brain imaging, genetics, molecular
biology, chronobiology, neuroimmunology or ...
2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award
... in Mumbai. He completed his doctoral work in molecular
evolutionary biology at the University of ... her work focuses on integrating genetic and molecular
methods to better understand the role selenium, ... one aspect of Peters' research. Incorporating molecular
and genetic approaches, she also studies vitamin ...
Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients
... "There has been very little understanding of the molecular
basis of this syndrome, but because of the ... dioxide occurs.
To better understand the molecular
mechanisms of disease exacerbation or, as Dr. ... of novel therapeutics that will target the molecular
pathways identified by our basic science ...
Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research
... Ullrich, Ph.D., director of the Department of molecular
Biology at the Max Planck Institute of ... was chosen for his pioneering work in applying molecular
biology and molecular
cloning to the discovery of protein therapeutics ...
New trigger for chronic inflammation in rheumatoid arthritis discovered
... the body, the body responds by turning on a molecular
switch to set the immune system into action and ... molecule called tenascin-C can trigger the same molecular
switch and also activate the immune system. High ... inflammation of rheumatoid arthritis.
switch is called TLR4, and is found on the ...
Computers aid in cracking deception in plants
... uncover biological forms of deception, known as molecular
"Molecular mimicry is a biological ... apply his computational research to the study of molecular
mimicry in an important plant pathogen, the ... from which the nematode feeds. Scientists think molecular
mimicry may be involved in this host-pathogen ...
Humans related to orangutans, not chimps, says new Pitt, Buffalo Museum of Science study
... seriously, and if it reopens the debate between molecular
biologists and morphologists, so much the ... and orangutans have long been overshadowed by molecular
analyses that link humans to chimpanzees, but that those molecular
comparisons are often flawed: There is no theory ...
Nanocrystals reveal activity within cells
... Berkeley Lab's nanoscience research center, the molecular
Foundry. "These single-molecule probes will allow ... we add drugs or other bioactive compounds."
Foundry post-doctoral researchers Shiwei Wu and ... might behave in a real biological system, the molecular
Foundry team incubated the nanocrystals with ...
Chemical in blood may explain susceptibility to bladder pain
... presence or lack of disease based on the samples' molecular
profiles. Infrared spectroscopy identifies the ... cystitis demonstrated nearly identical molecular
"It's a powerful enough technique that ... determined the chemical structures within those molecular
profiles, which showed that blood from cats with ...
They are young and need the job: A second chance for dangerous T-cells
... to reeducation. "We now intend to study at the molecular
level what makes a T-cell accessible for ... for us to understand this 'educability' at a molecular
level," Klein said, "because then we might be ... T-cells. We are also trying to decode the molecular
switch inside T-cells that controls this ...
GARP makes the difference
... the scientific journal Journal of Cellular and molecular
The immune system keeps us healthy: ... Research in Braunschweig have identified a molecular
factor that plays an essential role in Treg ... inhibit such a reaction: they mainly looked at molecular
features that both cell types have the one more, ...
American Society for Microbiology honors Melissa B. Miller
... B. Miller, Ph.D., D(ABMM), director, Clinical molecular
Microbiology Laboratory, assistant professor, ... research on the development and application of molecular
assays for use in the diagnosis of infectious diseases. She built the molecular
infectious disease diagnostic laboratory at UNC ...
Recruitment of reproductive features into other cell types may underlie extended lifespan in animals
... General Hospital (MGH) Department of molecular
Biology have found that certain genetic mutations ... somatic cells," says Sean Curran, PhD, of MGH molecular
Biology, the study's lead author. "We know that ... that damage other cells and understanding the molecular
pathways involved in that stability may someday ...
Singapore scientists elected into National Academy of Sciences
... Copeland, Executive Director of the Institute of molecular
and Cell Biology (IMCB) of Singapore's A*STAR ... National Cancer Institute (NCI). He headed NCI's molecular
genetics of oncogenesis section and was director ... cancer genetics program, while she headed the molecular
genetics of development section.
American Chemical Society's weekly PressPac -- May 27, 2009
... of a deadly complication of liver disease
A technique that "silences," ... study is scheduled for the June 1 issue of ACS' molecular
Pharmaceutics , a bi-monthly journal. Cirrhosis ... into the bloodstream to treat disease
Scientists are reporting a ...
MicroRNAs grease the cell's circadian clockwork
... reveals that an important regulator of this molecular
oscillator is a specific microRNA. The latter ... induce gene silencing
Ueli Schibler, from the molecular
Biology Department of the University of Geneva, ... Schibler's collaborators.
Performance of the molecular
The researchers' team has discovered ...
Lombardi scientist brings 'dream team' breast cancer research effort to GUMC
... to therapy or can recur. Understanding the molecular
diversity of human breast cancer has been a ... Laboratory, is focused on understanding the molecular
subtypes of breast cancer.
The Teams' goals include: expanding the underlying molecular
understanding of each subtype of breast cancer in ...
'Disordered' amino acids may really be there to provide wiggle room for signaling protein
... which serves as a means of bringing together molecular
signals between the outer membrane of a cell and ... allowing the protein to function as a molecular
switch, a process that is thought to go wrong in ... Roder says. "Here we show that the weak molecular
interactions in a disorganized protein sequence ...
The challenges of avian influenza virus: Mechanism, epidemiology and control
... to SARS infection. Therefore unraveling the molecular
pathogenesis mechanism will help save life. ... who has long been involved in the study of molecular
pathogenesis of SARS, describes our current understanding of the molecular
pathogenesis of H5N1 in human infection and ...
Why the thumb of the right hand is on the left hand side
... the renowned journal Current Biology , a team of molecular
biologists led by Pia Aanstad of the University of Innsbruck reports that a variety of molecular
mechanisms accounts for the interpretation of the ... group leader Pia Aanstad of the Institute for molecular
Biology of the University of Innsbruck. "The ...
Hunt for 'climate-ready' crops accelerates as organizations search seed collections worldwide
... GCP is offering funding for scientists to use molecular
mapping technology to identify the "DNA ... variety, one has to go further and also conduct molecular
analysis and then the breeding work. This work ... will make use of conventional plant breeding and molecular
markers to increase the ability of maize to cope ...
Tumor growth and chemo response may be predicted by mathematical model
... Tumors are complex systems, with changes at the molecular
and cellular levels influencing shape and ... that mathematical modeling based on data from the molecular
and cellular levels could shed light on tumor ... lab works by defining tumor biologic and molecular
properties relating to laboratory and clinical ...
Two new studies on circadian rhythms
... is so affected.
A related study, in molecular
Cell , tracks a clock protein in action, mapping ... a day.
The new work adds clarity to the molecular
underpinnings of circadian clocks, the finely ... canonical properties of rhythms that still lack molecular
description," said Dunlap.
"The one in ...
Association for Molecular Pathology joins ACLU to challenge gene patents
... Washington, DC May 13, 2009 The Association for molecular
Pathology (AMP) announced today that it is ... ovarian cancers.
The lawsuit, Association for molecular
Pathology, et al. v. U.S. Patent and Trademark ... sequence data to develop the tests needed to make molecular
medicine a reality," said Dr. Nowak.
Milestone in live microscopy focus of $2 million NIH grant
... to observe and record biological processes at the molecular
"A microscope with these capabilities ... Jodi Nunnari and Jon Scholey, professors of molecular
and cellular biology; Wolf Heyer, professor of ... will add an appointment in the Department of molecular
and Cellular Biology to his academic positions at ...
Molecules that orchestrate the processes of life
... is a journey into the sub-microscopic world of molecular
machines. Readers are introduced to the types of ... illustrations in this book to allow us to see the molecular
structure of cells, if not directly, then in an ... a fascinating introduction to biochemistry and molecular
biology for the non-specialist, and combines a ...
Stowers researchers develop whole genome sequencing approach for mutation discovery
... The Stowers Institute's Hawley Lab and molecular
Biology Facility have developed a "whole-genome ... carries the potential to pinpoint inheritable molecular
characteristics that are controlled by several ... Staehling-Hampton, Ph.D., Managing Director of molecular
Biology and co-equal senior author on the paper. ...
EMBL scientists develop first fully automated pipeline for multiprotein complex production
... Most cellular processes are carried out by molecular
machines that consist of many interacting ... developed by researchers at the European molecular
Biology Laboratory (EMBL) in Grenoble, France, ... and will allow to decipher as yet elusive molecular
mechanisms of health and disease.
ACEMBL can ...
March of Dimes awards $250,000 prize to scientists unraveling the causes of muscular dystrophy
... Institute investigator, is professor and head of molecular
Physiology and Biophysics at the University of ... Medicine. He is also the Roy J. Carver Chair of molecular
Physiology and Biophysics and Director of the ... Research Center. His work unraveled the molecular
mechanisms of muscular dystrophies.
DOE to establish Energy Frontier Research Center at PNNL
... million over five years for PNNL's new Center for molecular
Electrocatalysis, which will be led by PNNL ... and computational sciences. "The Center for molecular
Electrocatalysis will enable a group of ... the use of equipment at EMSL, DOE's Environmental molecular
Sciences Laboratory on the PNNL campus.
Analysis finds strong match between molecular, fossil data in evolutionary studies
... alone analyze their evolutionary dynamics, when molecular
techniques had already invalidated that approach? ... to reconciling the conflict between fossil and molecular
data in evolutionary studies.
For more than ... by fossils or by genetics.
Scientists using molecular
techniques assert that genetics more accurately ...
Nanoneedle is small in size, but huge in applications
... processes and biophysical properties at the molecular
level inside living cells," said
Min-Feng Yu, a ... The quantum dots can be used for studying molecular
mechanics and physical properties inside cells.
... handling, and coated with a thin layer of gold. molecular
cargo is then attached to the gold surface via ...
Symposia selected for Entomological Society of America meeting
... 13-16, 2009.
Integrative Physiological and molecular
Insect Systems Symposia:
Cold Case Files: Integrative Perspectives on Physiological and molecular
Responses of Insects to Low Temperature
... Classification and Systematics, Epidemiology, and molecular
Vector-borne Disease and Public ...
6 young ASU faculty earn NSF Career awards
... tackling fundamental questions about the use of molecular
probes in biosensors. With such knowledge he will ... MEMS devices, based on the way proteins with low molecular
weight are adsorbed (how substances condense on a ... displaced and exchanged by proteins with higher molecular
Biosensors typically ...
Mouse model provides a new tool for investigators of human developmental disorder
... Now, a study by scientists at the European molecular
Biology Laboratory demonstrates that a gene ... disorder. It provides a new avenue for molecular
research through study of Fgrf1 function, but ... Rosenthal and Pascal te Welscher of the European molecular
Biology Laboratory in Monterotondo, Italy. The ...
Springer partners with the American Society for Biochemistry and Molecular Biology
... with the American Society for Biochemistry and molecular
Biology (ASBMB) to publish The Encyclopedia of molecular
Life Sciences. The 11-volume work will be ... benefit our members."
The Encyclopedia of molecular
Life Sciences will focus on understanding ...