Navigation Links
Messenger in Biological News

Atomic-resolution views suggest function of enzyme that regulates light-detecting signals in eye

... is the so-called GAF A domain. A small messenger molecule, cGMP, binds to the GAF A domain to ... we can infer why it prefers cGMP over other messenger molecules." He added that the domain is quick in recognizing and responding to the messenger molecule to create an instantaneous flow of ...

Using novel tool, UD researchers dig through cell 'trash' and find treasure

... and responds to stress. MicroRNAs bind to messenger RNAs, which are longer molecules that carry ... cells to make proteins. "The microRNAs target messenger RNAs--they are out to destroy them--in plant ... In fact, the microRNAs direct enzymes to cut the messenger RNAs in two. The resulting decay products--or ...

N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets

... molecule for the correct positioning of the two messenger molecules -- one deep in the center of the ... to move inward, and then release the deeply bound messenger and its sodium partner into the cell. In the ... and stop the transport mechanism, leaving the messenger molecule outside the cell. The second team of ...

Researchers observe spontaneous 'ratcheting' of single ribosome molecules

... of tools to build proteins, beginning with messenger RNA, a ribbon-like molecule that codes for the ... protein chain. The ribsome transits along the messenger RNA as the protein is built, releasing the ... making room for the next tRNA specified in the messenger RNA code. The researchers believe that EF-G ...

UD researchers discover novel 'gene toggles' in world's top food crop

... to stress. These micro-molecules bind to specific messenger RNA molecules, which carry instructions to the ... proteins. This binding typically causes the messenger RNAs to be degraded in plant cells. We were ... strand, called the sense transcript, produces messenger RNA, which carries the recipe for making a ...

Deep into the machinery of adult fragile X

... mechanism for transporting the genetic material messenger RNA within neurons to protein-making sites. The ... in the mutant DNA gene are copied onto the messenger RNA that carries genetic information from the ... how the string of stutters in the abnormally long messenger RNA of FXTAS patients produces the neural ...

Researchers identify proteins involved in new neurodegenerative syndrome

... The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the ... syndrome have higher than normal levels of messenger RNA. messenger RNA or mRNA takes the proteins blueprint from the ...

New tool isolates RNA within specific cells

... method makes it possible to "listen in" to the messages -- in fact, messenger RNA -- that the nucleus is sending each cell, without perturbing the cell, ... delivery, electrical pulses of molecules through cell membranes, or messenger RNA injection. ...

Flow of potassium into cells implicated in schizophrenia

... control when neurons fire electrically discharge and release a chemical messenger that signals neighboring neurons in a circuit. This flow is regulated, in part, by activity of the chemical messenger dopamine, the main target of antipsychotic medications used to treat ...

CSHL scientists clarify editing error underlying genetic neurodegenerative disease

... segments -- called exons -- are pasted together, forming a mature messenger RNA transcript. In an unedited RNA molecule, the boundaries between an ... "atypical" sites, in other words, could be spliced to make the correct messenger RNA, despite the apparent mismatch. Atypical sites are recognized due ...

Study reveals surprising details of the evolution of protein translation

... in its unique L-shaped structure. One end of the molecule decodes messenger RNA (a molecule that carries instructions for the sequence of amino acids ... the refinement of the genetic code into codons, the regions on the messenger RNA that are read by individual tRNAs. "For the first time, we believe ...

Brain tweak lets sleep-deprived flies stay sharp

... to avoid the lighted vial, but sleep-deprived flies did not. A brain messenger known as dopamine is linked to some of the mental capabilities harmed by sleep loss. Researchers decided to test if this messenger could be used to block learning impairment in sleep-deprived flies. ...

Getting wise to the influenza virus' tricks

... of the host cell. The influenza virus steals a password from host messenger RNAs, molecules that carry the instructions for protein production, and ... RNA base called a cap, which must be present at the beginning of all messenger RNAs (mRNAs) to direct the cell's protein-synthesis machinery to the ...

Single-celled bacterium works 24-7

... energy metabolism, nitrogen fixation, respiration, the translation of messenger RNA (mRNA) to proteins, and the folding of these proteins into proper ... team examined the expression of 5,000 genes, measuring the amount of messenger RNA for each gene in alternating dark and light periods over 48 hours. At ...

Less can be more, for plant breeders too

... In plants, they cause highly specific degradation of sequence-matched messenger RNAs, which encode enzymes, regulatory factors or other proteins. The end ... by several years of breeding. With an artificial miRNA targeting the Eui1 messenger RNA, the researchers at the International Rice Research Institute obtained ...

Protein's new role discovered in autoimmune disease

... to autoimmune disorders like rheumatoid arthritis and lupus. The messenger is the naturally occurring chemical interleukin 17 (IL-17), an immunity ... the journal Nature Immunology . In the study, UAB scientists blocked messenger signals from the IL-17 protein to the immune system of mice. This ...

Parasites ready to jump

... class of molecules has been found in mice. By means of a process called RNA interference, the siRNAs enable the cell to recognize and destroy messenger RNAs derived from transposons. The researchers in Frstemann's group were able to identify a protein that is essential for the production of ...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... section of DNA where certain proteins known as transcription factors attach in order to recruit the cellular machinery used to transcribe genes into messenger RNA and then proteins. Studies in both cells and a mouse model for cancer showed that they could promote the expression of MYC by transfecting cells ...

DOE-funded research projects win 46 R&D 100 Awards for 2009

... palm of a hand, and this spectrometer is outfitted with an innovative low-powered, miniature cooling mechanism. GeMini was launched on NASA's Mercury messenger spacecraft and is now taking the first-ever gamma-ray data of the planet Mercury. GeMini also can be used to help prevent terrorists from smuggling ...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

... Dr. Rubin's team used state-of-the-art gene sequencing tools to discover the new class of gene fusion. Using pair-end digital sequencing of messenger RNA -- the message that all cells produce -- the computational team, lead by Dr. Mark Gerstein from Yale University and Andrea Sboner from Weill ...

Researchers see evidence of memory in the songbird brain

... The new study took a broad snapshot of gene activity in the brain. Using DNA microarray analysis, the researchers measured changes in levels of messenger RNAs in the auditory forebrain of finches exposed to a new song. These mRNAs are templates that allow the cell to translate individual genes into the ...

Scripps Research scientists observe human neurodegenerative disorder in fruit flies

... gene expression. Basically, when a gene is expressed, its double-stranded DNA is first transcribed into a corresponding single-stranded piece of messenger RNA. Then an enzyme called the ribosome uses the mRNA as a template to make a protein by reading out its genetic sequence and then translating it ...

New piece found in the puzzle of epigenetics

... in the fine regulation of the cell nucleus enzyme RNA polymerase II. This transcribes the genetic information of the genetic substance DNA into messenger RNA - mRNA for short which in turn is the basis for protein synthesis. At the same time RNA polymerase II is also responsible for the production of ...

Genetic switch potential key to new class of antibiotics

... and carry its messages. In the classical view of gene expression, instructions stored in deoxyribonucleic acid (DNA) chains are copied into messenger ribonucleic acids (mRNAs). The mRNAs are then transported to ribosomes that pair them with transfer RNAs that contribute amino acids into a protein ...

New insights into progressive hearing loss

... to equivalent microRNAs and to the equivalent region within the microRNA - just seven letters that are known to be important for interacting with the messenger targets. "The human variants of miR-96 identified in the affected families were found to alter activity of other genes in experiments in test ...

Penn biologists discover how 'silent' mutations influence protein production

... explained more than half the variation in protein levels. To understand this observation, the researchers simulated the spatial arrangement of the messenger RNA molecule that carries the information from genes to proteins. They found that the inefficient genes produced tightly folded mRNA molecules that ...

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

... thymidine, and guanosine. The pattern of these nucleotides dictates which protein is encoded by a given gene. DNA in the nucleus is transcribed as messenger RNA, which leaves the nucleus and begins making proteins based on the order of these four bases. A person's two copies of any gene may vary at these ...

Ambati study published in PNAS

... such as cholesterol. This is important, because siRNA must enter cells in order to function as intended by specifically degrading intracellular messenger RNA bound for protein-forming machinery. Furthermore, this finding strengthens their finding that TLR3 positioned on the cell surface is responsible ...

New technique used to profile anthrax genome

... genome is expressed and regulated." The RNA-Seq approach works by using a technique known as high throughput sequencing, which counts millions of messenger RNA (mRNA) sequences simultaneously. Although the method was used to define the transcriptomes of several eukaryotic organisms in 2008, applying it ...

Regulatory molecule for tumor formation or suppression identified by Singapore, US researchers

... member of the microRNA family of small regulatory molecules that have evolved in nature to regulate tightly the quantity of protein produced by each messenger RNA (mRNA), which generates the group of proteins that determine the unique characteristics of every cell type. MicroRNAs play complex roles in ...

Addiction: Insights from Parkinson's disease

... behavioural and mood symptoms, which are now being recognized as a major source of disability. Dopamine is a neurotransmitter, or chemical messenger in the brain that is involved in brain processes that control movement, emotional response and the ability to experience pleasure, reward and pain. ...

New models question old assumptions about how many molecules it takes to control cell division

... the effects of noise in a yeast cell revealed flaws in two accepted notions about information processing in single cells: about the numbers of messenger RNA (mRNA) molecules in a cell, and about how long they live. A fundamental challenge of systems biology is trying to understand the molecular ...

Calculating gene and protein connections in a Parkinson's disease model

... results from deleting a gene from a cell's genome and seeing what observable traits appear in the cell) and information on the cellular levels of messenger RNA (mRNA, which is the template for proteins). Historically, these two types of data have largely been analyzed independently of each other, ...

NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis

... and resistant traits of the very aggressive melanoma cell." miRNAs are short pieces of RNA that block the expression of proteins that are encoded by messenger RNAs. They serve as regulators of protein expression, acting like the volume control on a radio. In recent years, miRNAs have been linked to the ...

Bacteria are models of efficiency

... the machinery in which proteins are produced and RNA polymerase an enzyme that copies the genetic code for protein production onto strands of messenger RNA for further translation into proteins. RNA polymerase is thus a sort of work 'supervisor' that keeps protein production running smoothly, checks ...

Case Western Reserve finds mechanism underlying alt. splicing of premessenger RNA into messenger RNA

... in a gene's pre-messenger RNA (pre-mRNA) are discarded, and the remaining strings of nucleotides are spliced together into one continuous strand of messenger RNA (mRNA) that produces one unique protein. But regular splicing is insufficient to produce all the proteins in the human cell, where 25,000 ...

Properties of unusual virus revealed in research

... of Biochemistry and Molecular Biology and a leader of the study. "These phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process called transcription, which ultimately results in the creation of new phage proteins. These new proteins are used to construct ...

Researchers study virus with unusual properties

... of Biochemistry and Molecular Biology and a leader of the study. "These phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process called transcription, which ultimately results in the creation of new phage proteins. These new proteins are used to construct ...

Stowers Institute's Baumann Lab identifies key step in maturation pathway of telomerase

... processing for telomerase RNA uses a fundamentally different and novel pathway." "We demonstrate that the machinery that removes introns from messenger RNAs also functions in generating the mature 3' end of the telomerase RNA subunit," said Jessica Box, Research Technician I and co-equal first author ...

LSUHSC research identifies key contributor to Alzheimer's disease process

... Guo Cui, MD, PhD and Yuhai Zhao, a post doctoral student in the lab, demonstrated in human brain cells in primary culture that MiRNA-146a targets the messenger RNA of an important anti-inflammatory regulator called complement factor H (CFH). Testing both control cells and Alzheimer's disease-affected ...
Other Contents
(Date:7/30/2014)... Americans make better decisions about what they eat, the ... significant changes to the Nutrition Facts label found on ... in Chemical & Engineering News (C&EN), the ... the suggested updates and the fight that has ... points out that while the Nutrition Facts label has ...
(Date:7/30/2014)... awarded the Scientific Committee on Antarctic Research,s (SCAR) ... SCAR, an inter-disciplinary international science body, initiates, develops ... the Antarctic region, and on the role of ... organisation also provides scientific advice about Antarctica to ... region. , The medal is open internationally to ...
(Date:7/30/2014)... a multitude of cells types. Researchers would like to understand ... mature cells that make up the organs and other structures ... long chains of sugars that dangle from proteins on surfaces ... California, San Diego, has created synthetic molecules that can stand ... manipulated to direct the process, they report in the ...
Breaking Biology News(10 mins):
(Date:7/30/2014)... Ticket Down is a reputable source for affordable ... on Saturday, August 2nd. Two of the most popular ... on American soil on Aug. 2 when Manchester United and Real ... home of the University of Michigan is also known as Michigan ... of American sports and has also hosted numerous other monumental events ...
(Date:7/30/2014)... happen in an instant: A small child pulls up on ... injured when the furniture tips over. "Every parent or ... and imagine what could tip over, fall off walls and ... a reality," Dr. Alex Rosenau, president of the American College ... Between 2009 and 2011, roughly 43,000 people ended up in ...
(Date:7/30/2014)... Imprivata ® (NYSE: IMPR), ... secure communications solutions for the healthcare industry, today ... most widely selected single sign-on (SSO) solution amongst ... medical records (EMR) systems with a 51 percent ... in the last 12 months), according to HIMSS ...
(Date:7/30/2014)... Louisville, KY (PRWEB) July 30, 2014 ... is pleased to announce the launch of its ... free, online resource for medical professionals and equipment vendors. ... trade shows and conventions in the United States and ... on the calendar, and that number is always growing. ...
(Date:7/30/2014)... Angeles, CA (PRWEB) July 30, 2014 ... the Chao Pinhole Surgical Technique®, the revolutionary minimally invasive ... Dennis Shanelec, considered by many of his peers to ... special guest speaker at a recent Chao Pinhole Surgical ... Alhambra, CA. Dr. Shanelec is the recipient of the ...
Breaking Medicine News(10 mins):Health News:Manchester United vs. Real Madrid Tickets Ann Arbor: Ticket Down Slashes Ticket Prices for Real Madrid vs. ManU Guinness International Champions Cup Match 2Health News:Manchester United vs. Real Madrid Tickets Ann Arbor: Ticket Down Slashes Ticket Prices for Real Madrid vs. ManU Guinness International Champions Cup Match 3Health News:Manchester United vs. Real Madrid Tickets Ann Arbor: Ticket Down Slashes Ticket Prices for Real Madrid vs. ManU Guinness International Champions Cup Match 4Health News:Tip-Over Furniture Can Kill Kids 2Health News:Imprivata Achieves 51 Percent Single Sign-on Market Share Amongst U.S. Hospitals Using McKesson Paragon or Horizon EMR Systems, According to HIMSS Analytics 2Health News:DRE Launches Online Interactive Medical Trade Show Calendar 2Health News:Periodontist Dr. Dennis Shanelec Comments On The Chao Pinhole Surgical Technique® Training Course 2
Other TagsOther Tags