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Menopause in Biological News

Identification of genetic variants affecting age at menopause could help improve fertility treatment

... factors that influence the age at which natural menopause occurs in women. Ms Lisette Stolk, a ... understanding of the factors influencing age at menopause might eventually help to improve the clinical ... Stolk, "and women who had one of them experienced menopause nearly a year earlier than others. We know that ...

Study finds genetic links to age of first menstrual period and menopause

... their first menstrual period and the onset of menopause may help shed light on the prevention of breast ... ). Menarche and natural menopause are two important physiological events in a woman's life. An early onset of menarche and later menopause are well-established risk factors for the ...

Men shed light on the mystery of human longevity, study finds

... gradual rise in mortality after the age of female menopause without relying on 'grandmother' effects or ... was substantial at ages well past female menopause for much of human history and the result ... mutations acting after the age of female menopause are selected against ... solely as a result of ...

Older killer whales make the best mothers

... Killer whales ( Orcinus orca ) nearing the menopause may be more successful in rearing their young. New research published in ... that during a calf's first year of life, having a mother who was nearing menopause increased chances of survival. According to Ward, "We found that the ...

New study shows compounds from soy affect brain and reproductive development

... of the brain, resulting in early-onset puberty and symptoms of advanced menopause in research animals, according to a new study by researchers at North ... of the rats' estrus cycle which would be corollary to early onset of menopause in a human. The study also showed that genistein caused the early onset of ...

American Chemical Society's Weekly PressPac -- Aug. 15, 2007

... many women have suspected about the hormonal changes that accompany aging: menopause can make you fat. Scientists long have sought to understand how changes in hormones during menopause could account for the increase in appetite and accompanying weight gain ...

Ovarian transplantation: First baby is born after a new technique

... nodosa, an inflammation of medium-sized arteries, which become swollen and damaged from attack by rogue immune cells. "She suffered menopause for eight and a half years before transplantation," said Dr. Piver. "But after transplanting half of the frozen ovary, she recovered spontaneous ...

Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease

... is dependent on it. Steroid receptors also have a role in cardiovascular health, including the protective role estrogen seems to have in women before menopause and the fact that testosterone doesn't seem to do the same for men of any age. "So how do you get both things? Receptors of these hormones need Hsp90 ...

NAU discovery could help feed millions

... that low, nontoxic doses of VCD in mice sped the menopausal process and rendered them infertile. She dubbed this new animal model of accelerated menopause "mouseopause." Mayer and her colleagues have developed a product called ContraPest that incorporates the chemical sterilization treatment into ...

Study finds link between hot flashes and lower bone density in women

... and health services research, are available for interviews. JOURNAL: The research appeared in the March/April 2009 issue of the journal menopause . FUNDING: The National Institute on Aging, the U.S. Department of Health and Human Services' National Institutes of Health, the National ...

Late motherhood boosts family lifespan

... of species, including humans, are able to reproduce late without medical intervention and those females live longer." Other studies found that late menopause also is associated with women having prolonged fertility and longevity. "There is a genetic component to longevity, especially for living to very ...

Hispanic women and breast cancer: An understudied group

... significantly older at diagnosis at 53.8 years compared with 48.7 years in the United States. Reproductive data showed a similar age at menarche, menopause and first pregnancy. However, the number of live births was higher in Mexico at 3.7 vs. 3.2 in the United States. Prevalence of family history of ...

M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan

... has shown that mutations of the fragile X gene can cause, among other disorders, autism and ADHD in children, anxiety disorders at all ages, early menopause in women and dementia in the elderly. Because the potential impact is so great, M.I.N.D. Institute researchers have created an inexpensive spot ...

17th Annual Congress on Women's Health convenes

... Women, American Thyroid Association, Arthritis Foundation, National Stroke Association, National Women's Health Resource Center, The North American menopause Society, and WomenHeart: The National Coalition for Women with Heart Disease. Congress Chair Wendy S. Klein, MD, Senior Deputy Director Emeritus ...

Quest for better treatment for effects of menopause

... Ainhoa Ruiz del Agua, studied the effects of substitute treatments and the genetic factors influencing the response to these therapies. menopause is a natural period in the ageing process of a woman. On ceasing the ovary function, the body gradually stops producing eggs and female sex hormones ...

Oocyte-specific gene mutations cause premature ovarian failure

... but Rajkovic believes it can accelerate the loss of eggs (or germ cells). When all the eggs are lost, the ovaries stop producing estrogen, leading to menopause symptoms. In this study, Rajkovic and his collaborators screened 100 Chinese women with premature ovarian failure for mutations in FIGLA and ...

Wild chimpanzees appear not to regularly experience menopause

... suggests that human females are rare or even unique among primates in experiencing a lengthy post-reproductive lifespan. "We find no evidence that menopause is common among wild chimpanzee populations," says lead author Melissa Emery Thompson, a postdoctoral researcher in anthropology at Harvard ...

New study reveals for first time how BRCA1 mutations cause breast cancer

... removed instead of waiting for cancer to appear. Breast cancers caused by BRCA1 mutations tend to affect women much earlier often before menopause and sometimes in their 20s and 30s and between 60 and 80 percent of women who carry a BRCA1 mutation will develop breast cancer at some point during ...

Male chimpanzees prefer mating with old females

... and that female fertility is limited by menopause and, therefore, age. The converse of such an ... that appear to lack long-term pair bonding and menopause (such as chimpanzees) should not exhibit such ... the idea that long-term pair bonding and menopause may contribute to the preference of human males ...

Fish evolve a longer lifespan by evolving a longer reproductive period, researchers find

... by natural selection. This result could be of interest to those who study menopause in humans and who have argued that post-reproductive humans can increase ... our results show how it would be possible to evaluate whether or not menopause in humans has been shaped by natural selection. Appropriate comparisons, ...

Researchers find gene mutation that causes infertility in male mice

... the researchers found that female mice with the Dmc1 mutation are born with fewer egg cells and can run out of eggs prematurely -- resulting in early menopause (or "mousapause" as the researchers humorously refer to the condition). To get their results, the researchers randomly induced mutations in the ...

Down syndrome: It's not just the age factor

... increasing maternal age. There is strong evidence for uterine selection against genetically disadvantaged embryos. However, as women approach the menopause and the risk of future infertility increases, this selection, or filtering stringency, is expected to relax. Neuhäuser and Krackow's paper ...

New research: Soy germ isoflavones reduce bone loss

... cancer and breast cancer." "It is imperative to find natural, safe and effective alternatives for women to help maintain bone health after menopause ?without the risky side effects associated with long-term hormone replacement therapy use. This promising research is another step in advancing soy ...

Getting an evolutionary handle on life after reproduction

... postreproductive lifespan can influence fitness enough to be under selection. But in a field dominated by investigations into the origins of human menopause and extended lifespan, the authors make a strong case for using experimental comparative analyses of other species to gain an evolutionary ...

Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy

... with shakuyaku-kanzoto; neither found a beneficial effect. "Some herbal medicines show promise for the treatment of problems with menstruation and menopause and other conditions that affect women," said Warren. "It is unfortunate that their quality and safety are not better controlled. Such an environment ...

Women cautioned against using herbal supplements

... with shakuyaku-kanzoto; neither found a beneficial effect. "Some herbal medicines show promise for the treatment of problems with menstruation and menopause and other conditions that affect women," said Warren. "It is unfortunate that their quality and safety are not better controlled. Such an environment ...

Stem cells in bone marrow replenish mouse ovaries

... fertility. In addition, the findings open the door for future studies examining whether restoration of ovaries could postpone the hormonal effects of menopause and could represent an alternative to hormone replacement therapy. Finally, the researchers would like to find out whether these stem cells could be ...
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