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Marker in Biological News

Tips from the American Journal of Pathology

... of stromal caveolin-1 expression as a prognostic marker for breast cancer progression. These articles ... value of epithelial caveolin-1 as a prognostic marker has been limited. Witkiewicz et al and Sloan ... microenvironment and serve as a new prognostic marker for breast cancer progression. Dr. Mina ...

Tips from the American Journal of Pathology

... Am J Pathol 2009, 174: 1443-1458 New marker for Prostate Cancer Progression Avraham Raz ... have identified a cleaved form of galectin-3 as a marker for prostate cancer progression. These data are ... therapies. Decreased expression of the marker galectin-3 has been reported to correlate with ...

Biomedical research profits from the exploration of the deep sea

... molecules responsible and their application as marker in living cells. Many marine organisms such as ... protein, named cerFP505, can be well applied as marker protein in mammalian cells at normal body ... an ideal lead structure for the development of marker proteins for super-resolution microscopy, say the ...

Researchers devise means to create blood by identifying earliest stem cells

... not more so, we've got ACE as a 'new' old marker to guide our work," Zambidis adds. Researchers ... as well as new ways to find and manipulate this marker to make them grow." The team's findings, ... The researchers found not only that ACE was a marker for hemangioblasts, but turning off the enzyme ...

Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds

... Surgeons shows elevated plasma DNA is a reliable marker of recurrent esophageal cancer. The study also ... is usually diagnosed at a late stage. An accurate marker for detecting esophageal cancer that has spread ... and specificity of plasma DNA as a preoperative marker of metastasized disease and a ...

UM researchers find new marker to identify cancer stem cells

... Michigan Comprehensive Cancer Center have found a marker that can be used to identify stem cells in breast ... worst outcomes, suggesting this easily detected marker could be used to assess prognosis. This study is a big step because it provides a marker thats easy to use in both normal and cancer ....

Team of scientists develops non-invasive method to track nerve-cell development in live human brain

... new nerve cells are known to be generated. The marker was not detected in the cortex and other parts of ... in the adult brain. The newly discovered marker can be detected when NPCs stem-like progenitor ... health. Discovery of the neural stem cell marker relied heavily upon the development of an ...

Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding

... to breed out of season, the researchers caution that it may only be a marker for the gene actually responsible for the trait. "Breeding out of ... the researchers said, as recombination could occur between the marker and the functional gene. Thus, the researchers stress that it will be ...

Holding breath for several minutes elevates marker for brain damage

... function. The study is "Increased serum levels of the brain damage marker S100B after apnea in trained breath-hold divers: a study including ... was 6 minutes 43 seconds and the shortest was 4 minutes 41 seconds. The marker for brain damage, S100B, rose in seven of the nine divers. The controls ...

Stem cell 'daughters' lead to breast cancer

... one day help guide diagnosis and treatment. "For example, c-KIT is a key marker of the luminal progenitor cell and I expect we will see an increase in pathologists routinely using this as a diagnostic marker for basal-like tumours," she said. "It may even be possible to develop new ...

Major breakthrough in early detection and prevention of AMD

... Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD), the leading cause ... process, but Dr. Ambati's studies have now identified CCR3 as a key marker of the CNV process involved in AMD. If researchers can determine why CCR3 ...

Stem cell focus for IBD wound healing

... He said: "The study will focus on the molecule CD24 which is a stem cell marker and which plays a key role in cell proliferation and the migration of ... attached to the cell membrane which has been recently reported as a marker of stem cells in the colon. It occurred to us that CD24 might have a role ...

Distinguishing single cells with nothing but light

... procedures where markers are inserted in, or attached to cells. If a marker sticks to one cell, and not the other, you can tell which cell is which on ... monitoring a cell over time as it changes is more problematic, since the marker can affect dynamic cell activities, like membrane transport. And internal ...

American Chemical Society's Weekly PressPac -- Dec. 3, 2008

... publication, Vuokko L. Kinnula and colleagues point out that no disease marker for COPD currently exists, despite extensive efforts by scientists to find ... "Proteomics of Human Lung Tissue Identifies Surfactant Protein A as a marker of Chronic Obstructive Pulmonary Disease" DOWNLOAD FULL TEXT ARTICLE ...

Apple or pear shape is not main culprit to heart woes -- it's liver fat

... liver that influenced metabolic risk. "Abdominal fat is not the best marker for risk," says Klein, who also directs the Nutrition Support Service at ... insulin and muscle tissue does, too. This tells us fat in the liver is a marker for metabolic problems throughout the entire system." The findings ...

Height linked to risk of prostate cancer development and progression

... PHILADELPHIA A man's height is a modest marker for risk of prostate cancer development, but is more strongly linked to ... height may also influence cancer and height is therefore acting as a marker for the causal factors," Zuccolo said. ...

Protein marker for schizophrenia risk

... A protein found in immune cells may be a reliable marker for schizophrenia risk, report researchers in a new proteomics study ... onset, but the researchers suggest they could be a useful and simple marker for evaluating schizophrenia risk. Although they believe that more markers ...

New source of heart stem cells discovered

... Each time the Wt1 gene in these cells was activated, RFP lit up. Since the marker is inherited by descendants of the Wt1-expressing cell, the researchers could identify these descendants by looking for RFP. "If the marker shows up in a cardiomyocyte, then I know that cardiomyocyte came from the ...

UV lotion lights the way to cleaner facilities

... surfaces to determine whether C difficile spores were present. The UV marker revealed that the commodes for the seven patients isolated with C. ... of spore. Nevertheless, we would still recommend that monitoring with a UV marker becomes a routine part of a hospital's housekeeping quality assurance ...

Answer to troublesome question of why some genetic assoc. studies have failed replication attempts

... Medical School and Brigham and Women's Hospital. "In this example, the marker may increase obesity in early life and then as time goes on, other effects become stronger, and the influence of this marker diminishes. It is likely that many other genetic variants also act in this ...

Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery

... Bridges group was the first in the world to convincingly demonstrate that marker genes could be efficiently inserted into the majority of heart muscle ... cell. The new grant will enable Dr. Bridges to move beyond his work with marker genes and begin testing his findings using therapeutic genes in sheep with ...

UCR researchers awarded nearly $1.7M to develop improved cowpea varieties

... modern plant breeding approaches that employ new and efficient molecular marker development methodologies. Molecular markers are landmarks that ... Close explained. Breeders wanting the disease resistance trait then use marker information to identify individuals containing that specific combination ...

New genetic variant associated with prostate cancer in African-Americans

... genetic variation among African American men that was an even stronger marker for cancer risk for these men. That variation is located within a gene ... more strongly associated with prostate cancer in African Americans. This marker was located within a gene that is involved in DNA replication, ...

Study reveals possible genetic risk for fetal alcohol disorders

... attention, memory and impulse control. By identifying a genetic marker that might signal susceptibility to these more subtle fetal ... behavioral problems in these children," says Schneider. "If this genetic marker could provide a way of recognizing the most vulnerable fetal ...

Mice use specialized neurons to detect carbon dioxide in the air

... if the GC-D enzyme is responsible for detecting carbon dioxide. "GC-D is a marker for the neurons that have specific carbon dioxide sensitivity," Mombaerts says. "At this time, we have not shown that the marker is mechanistically involved in sensory perception of carbon dioxide." The ...

Pitt researchers find promising candidate protein for cancer prevention vaccines

... cells because they, too, overproduce cyclin B1. The virus actually packages the host protein, which ultimately gets shown to the immune system as a marker of infected cells that must be destroyed. "Because cyclin B1 is a 'self' protein, there have been concerns that boosting the immune response ...

University of Toronto helps to 'barcode' the world's plants

... used to catalogue the world's plants using a technique known as DNA barcoding a rapid and automated classification method that uses a short genetic marker in an organism's DNA to identify it as belonging to a particular species. "Barcoding provides an efficient means by which we can discover the many ...

Study finds DNA barcoding requires caution without closer examination

... the identification, or in some cases even the definition of a species to a small sequence of DNA. He suggests that the search for a DNA barcoding marker or limited set of such markers that reliably identify the majority of life forms will be a continuously elusive goal. ...

UT San Antonio researcher wins $917,000 from NIH to study memory

... events occurred; 'when' is also a crucial variable. We believe the continual generation of new neurons in both rats and humans serve as a temporal marker for highly similar memories. Because time also plays a role in memories, the contribution of these new neurons to episodic memory is the focus of ...

A urine test for appendicitis?

... Seven promising urine biomarkers were identified. The best of them was leucine-rich alpha-2-glycoprotein (LRG), which appears to be a specific marker of local inflammation. It had an "area under the curve" value of 0.97, indicating near-perfect sensitivity (with almost no false-negatives) and ...

Prostate Cancer Translational Research in Europe meeting: Search for biomarkers continues

... of Prof Hamdy), PCA3 (Jacques Schalkens (Nijmegen, NL) group) and multikallikreins (project of Profs Lilja (New York, US) and Petterson). An across marker validation study is ongoing. "We can name the European prostate biobank, increased support of the validation of biomakers and the prostate risk ...

Chemical in blood may explain susceptibility to bladder pain

... COLUMBUS, Ohio A marker in the blood of both cats and humans that was identified in a recent study might signal both species' susceptibility for a painful bladder disorder ...

Gene activity reveals dynamic stroma microenvironment in prostate cancer

... those who really need treatment from those who might not? Can we identify the biomarkers that differentiate those? There is probably more than one marker and some may be stromal-based." ...

Olympus broadens portfolio with new biliary metallic stent

... the stent features five radiopaque markers that allow physicians to determine the position of the stent under an X-ray prior to deployment. A black marker is positioned at the proximal end of the stent facilitating endoscopic confirmation of the stent during deployment. The ease of deployment combined ...

New journal on advanced glass research to debut

... Alexis Clare (Alfred University), William Fahrenholtz (MS&T), Hua-Tay Lin (Oak Ridge National Laboratory, David Morse (Corning Inc.) Alexander marker (Schott USA), Kathleen Richardson (Clemson University), Emilio Spinosa (Owens Illinois) and George Wicks (Savannah River National Laboratory). Pye ...

Caffeic acid inhibits colitis in a mouse model -- is a drug-metabolizing gene crucial?

... . Researchers at Iowa State University have found that increased expression of a form of cytochrome P-450 (CYP4B1) is a key marker of inhibition of colitis in mice by caffeic acid, an anti-inflammatory antioxidant compound widely distributed in foods. The results, which appear ...

Genetic factors may predict depression in heart disease patients

... diseases, such as atherosclerosis and platelet aggregation appear to contribute to depressive symptoms. Specifically, they identified one marker within the vonWillebrand factor (vWF) gene that appears to have a significant association. vWF is a protein produced by the endothelium that is ...

MIT’s implantable device offers continuous cancer monitoring

... the first implantable device that can do just that. Cima and his colleagues recently reported that their device successfully tracked a tumor marker in mice for one month. The work is described in a paper published online in the journal Biosensors & Bioelectronics in April. Such implants ...

American Chemical Society's weekly PressPac -- May 6, 2009

... the impure honeys from the pure versions based on differences in their sugar content. MTS ARTICLE #3 FOR IMMEDIATE RELEASE "Polysaccharides as a marker for Detection of Corn Sugar Syrup Addition in Honey" DOWNLOAD FULL TEXT ARTICLE: ...

Native Americans descended from a single ancestral group, DNA study confirms

... and Evolution . The team's work follows up on earlier studies by several of its members who found a unique variant (an allele) of a genetic marker in the DNA of modern-day Native American people. Dubbed the "9-repeat allele," the variant (which does not have a biological function), occurred in ...
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(Date:7/11/2014)... is creating a new professorship in tissue engineering ... for Molecular Engineering and the Marine Biological Laboratory, ... Millicent and Eugene Bell Foundation., The Eugene Bell ... Institute for Molecular Engineering. That endowed chair holder ... MBL,s Eugene Bell Center for Regenerative Biology and ...
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