Study reveals how viruses collectively decide the fate of a bacterial cell
... the pathway that kills the host cell called the lytic
pathway or the pathway where it remains dormant ... cell called the lysogenic pathway.
When the lytic
pathway is selected, the virus utilizes bacterial ... change, which can result in a switch to the lytic
The decision of the genetic circuit ...
Metastatic bone disease patients can walk in Lazarus' footsteps
... said Anselmetti. He noted that osteoplasty provided effective pain regression for individuals with both painful bone metastases and benign lytic
lesions that didn't respond to conventional analgesic treatment.
Bones are the third most common location where cancer cells spread and ...
New paper sheds light on bacterial cell wall recycling
... wall components to observe the chemical reactions that take place during the recycling process.
The researchers found that a member of the lytic
transglycosylases family of enzymes known as M1tB performed the requisite cell wall fragmentation on the synthetic sample of the cell wall from their ...
Control switches found for immune cells that fight cancer, viral infection
... and then starts secreting the acid and other compounds that break down the bone."
NK cells have to form a similar plunger-like bond, known as a lytic
synapse, with the targets they attack. They do not make cortactin but produce HS1, which is a very similar protein. Butler decided to see what would ...
Researchers wake up viruses inside tumors to image and then destroy cancers
... experiments, this experimental therapy, called lytic
induction therapy, results in tumor death.
... one of the genes that is expressed upon viral lytic
induction is EBV's thymidine kinase (EBV-TK), an ... a proteasome inhibitor, but it also induces the lytic
cycle thereby activating the TK in the ...
Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
... and Metastases with a Combination of LHRH and lytic
Peptide, Hecate, bound to Iron Oxide ... they found evidence that the alternating LHRH and lytic
peptide on the ironoxide particle was effective ... the cell membrane. "It is possible that if the lytic
peptide has no interaction with the membrane it ...
Researchers from the UGR use a bacterium to obtain biopreservatives from food
... for nutrients in their environment. One of these strategies is to produce antimicrobial compounds such as antibiotics, certain metabolism products, lytic
agents, numerous types of protein exotoxins, and bacteriocins. It has become increasingly more necessary to find new antimicrobial agents because of ...
Finnish scientists discovered a new approach to treat virus-induced lymphomas
... patients. There are no current therapies effective against the aggressive KSHV-induced PEL. KSHV displays two patterns of infection: latent and lytic
phase. During latency, only a restricted set of viral genes is expressed. The KSHV genome encodes several homologues of cellular proteins, which ...
Worms produce surprise insight into human fever
... cells, including ours. These conserved pathways are involved in many similar “effector?strategies against hostile bugs peristalsis, low gut pH, lytic
enzymes, and antimicrobial peptides to prevent microbial colonization of the intestine.
In dissecting two conserved pathways required for C. ...
Newly discovered protein kills anthrax bacteria by exploding their cell walls
... conditions. "PlyPH works in an extremely wide pH range, from as low as four to as high as eight," says Fischetti. "I don't know of any other lytic
enzyme that has such a broad range of activity."
In addition, PlyPH, like PlyG, is highly specific in terms of the types of bacteria it affects. ...