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Linkage in Biological News

Human genomics in China

... extent. The rise of other molecular "omics" further strengthened the linkage of "big science" and "small science". For such a tremendous impact of this linkage upon life science research and the development of biotechnology, it is ...

Research pushes back history of crop development 10,000 years

... biology." "This lengthy development should favour the close linkage of domestication syndrome trait genes which may become much more ... easier. Interestingly, as more crop genomes become mapped, the close linkage of two or more domestication syndrome genes has been reported on several ...

World-first to predict premature births

... of Melbourne recently received an Australian Research Council (ARC) linkage Grant of $390,000 to fund the project for three years. "We are creating ... have enabled us to develop early findings and attract funding through ARC linkage Grant scheme," Professor Roger Smith said. ...

Concentrating on different aspects of pain leads to breakthrough in migraine genetics

... locus on chromosome 10q23, which showed significant evidence of genetic linkage in both populations studied as well as in the replication study. The gene ... This study is the first international collaboration as well as the largest linkage study in migraine to date. It successfully applied new analysis strategies ...

Landon Foundation-AACR INNOVATOR Awards

... the villages. They will apply the AACR INNOVATOR grant to their study of linkage analysis to identify the predisposing gene or genes for mesothelioma among this cultural group and map the genetic risk factors by genetic linkage studies. Findings from this research have implications far beyond the ...

PRS And EmSense Partner To Integrate Bio-Sensory Measures In Packaging Research Studies

... - and to identify the specific design elements driving the recent failure of Tropicana's new packaging. These new insights, which help uncover the linkage between visibility, cognition, emotion and purchase, will now be available within PRS On-Shelf Packaging Assessment studies. Scott Young, ...

Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine

... her studies have focused on the biomedical significance of the meprin proteases. With colleagues from the National Institutes of Health, she found a linkage between the meprin gene and vulnerability to diabetic nephropathy in Pima Indians in the southwestern United States. "These types of transitional ...

Springer partners with the American Society for Biochemistry and Molecular Biology

... of the work. Bell said, "In an era of increasingly multidisciplinary science, the Encyclopedia of Molecular Life Sciences will provide unprecedented linkage between cutting-edge science and the foundational theories and principles essential for understanding the molecular nature of life processes. It ...

Altered gene can increase risk of schizophrenia

... is one which Brzustowicz has been studying for six years. The paper also presents an innovative statistical method, Posterior Probability of linkage Disequilibrium (PPLD). This is the work of co-author Veronica Vieland of The Research Institute at Nationwide Children's Hospital, Columbus, Ohio. ...

Historical increase in corn yield -- it's in the roots

... Graeme Hammer of The University of Queensland (UQ), conducted this study on the leaves and roots of corn as part of an Australian Research Council linkage project with Pioneer Hi-Bred International. The project included scientists from UQ, Queensland Department of Primary Industries, and Pioneer. ...

Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

... lead to increased incidence and severity of heart failure following myocardial infarction. This is a major step forward in our understanding of the linkage between diabetes and cardiovascular disease". ...

Stress may hasten the growth of melanoma tumors

... producing these compounds. The researchers showed that the norepinephrine molecule binds to receptors on the surface of cancer cells and once this linkage occurs, it stimulates the release of the proteins that support angiogenesis and tumor growth. Yang and Glaser first confirmed that the receptors ...

42nd Mid-year Topical Meeting of the Health Physics Society

... Health in a radiological emergency Advances in radiation detection instrumentation (Monday p.m. session) Credit card radiation dosimeter GPS linkage to ground detectors Real-time mapping of radiological data Mobile labs Identifying enriched uranium Federal Agency planning (Tuesday a.m. ...

UT Southwestern researchers identify gene linked to inherited form of fatal lung disease

... lung disease?" In the current study, Dr. Garcia and her team focused on families that did not have TERC or TERT mutations. By using a genomic linkage approach a technique that scans the entire human genome for regions of DNA that are shared in common by all the individuals with the disease they ...

MU researcher identifies possible genetic causes of borderline personality disorder

... of siblings and 561 parents to identify the location of genetic traits that influences the manifestation of BPD. The researchers conducted a genetic linkage analysis of the families and identified chromosomal regions that could contain genes that influence the development of BPD. Trull found the strongest ...

Research consortium to sequence turkey genome

... genome sequence as well." The turkey genome sequence will enable the integration of other turkey research tools and resources, such as genetic linkage and cytogenetic maps, expressed sequenced tags, predicted genes and proteins, regulatory regions, and other resources. It will also serve as a ...

Sedimentary records link Himalayan erosion rates and monsoon intensity through time

... contain sediments that were eroded from the Himalaya, where the principal rainfall comes from South Asian monsoon storms--to argue for a linkage between the two monsoon systems over most of the past 23 million years. The most interesting correlation was found when the team compared the ...

Fitness in a changing world

... of Eda low were more successful at surviving. In retrospect, these data might not be so surprising given the results from Cresko on the additional linkage blocks. Selection is likely directly on the Eda alleles when the fish is older, but may be on the other linked genomic blocks when the fish is ...

Tracking down the cause of mad cow disease

... was produced with the use of bacteria and was given an additional thioester (a sulfur-containing group). The centerpiece of the new concept is the linkage of the protein and anchor by means of a native chemical ligation, in which the cysteine group reacts with the thioester. This allowed the prion ...

Carbon Disclosure Project: 'World's largest corporations seek clarity on climate change regulation'

... management rose to 204 (65%) compared with 141 (50%) responding companies last year. A total of 94 responding companies (30%) report some degree of linkage between employee incentives and goals related to climate change. Action lags behind awareness Although 254 companies (81% of respondents) ...

TGen investigators devise faster, cheaper way of analyzing the human genome

... technology,'' the study said, "it is clear that next-generation technologies are immediately useful for focused, hypothesis-driven sequencing of linkage peaks, groupings of candidate genes or sequencing the entire known coding sequence of the human genome.'' ...

Senescence in liver cells is found by CSHL scientists to help limit acute tissue damage

... cells don't divide could work against processes that cause cells to divide uncontrollably -- the hallmark of cancer -- it was the mechanics of the linkage that surprised Lowe's team. When they activated p53 in mice with HCC, tumors receded -- and this regression was associated directly with activation ...

Aerosol toxins from red tides may cause long-term health threat

... in Charleston, S.C., determined that brevetoxins react with DNA of lung tissue and attach to the DNA-bases that code genetic information. The linkage of chemicals in the environment to DNA is a first step for many cancer causing agents and can lead to mutations in genes that normally prevent the ...

A single mechanism for hypertension, insulin resistance and immune suppression

... Schmid-Schnbein said his findings will likely spark follow-up studies of this mechanism in humans. Even if future studies only support the clear linkage of hypertension to insulin receptor cleavage in the current study of SHRs, this observation should lead to many studies of how these two problems ...

LIAI researchers discover new cellular mechanism that will significantly advance vaccine development

... Shane Crotty, Ph.D., the lead researcher on the paper, "Selective CD4 T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities." Alessandro Sette, Ph.D., a renowned vaccine expert and director of the LIAI Center for Infectious Disease, also was a key ...

Sugar linkage could lead to better treatment for autoimmune diseases

... referred to as glycans, and on the tip of this glycan is a specifically linked sialic acid. All the sialic acid on IVIG was converted to the active linkage that confers anti-inflammatory properties. Understanding and analyzing the exact structure of sialic acid was the contribution of the UNH ...

A new idea for how anti-aging products delay ripening of fruit and wilting of flowers

... to make a carbene. When the carbene is generated by the copper in the ethylene receptor, it is the receptor that reacts, creating the permanent linkage that prevents the receptor from perceiving ethylene. According to Pirrung, knowledge of a chemical reaction between 1-MCP and copper in ethylene ...

AIBS honors outstanding contributions to the biological sciences

... Deans and Directors. Blocksteins writing, mentoring, and organizational talents have bolstered environmental science policy, improving the linkage between science and decisionmaking on environmental issues, and increased the representation of minorities in the sciences. Blockstein is founding ...

Crop management strategies key to a healthy Gulf, planet

... bioenergy features and ecological and biological feedbacks. While water availability and quality emerges as one of the most limiting factors, the linkage between water and bioenergy choices on medium and large scales is poorly qualified, according to Dale. An approach that considers environmental and ...

The future of solar-powered houses is clear

... doesnt need powered cooling or heating in Queensland. Professor Bell said the solar cell glass was the subject of two Australian Research Council linkage grants to QUT researchers to investigate ways to increase its energy absorption and to reduce the effects of shadowing, where overcast skies and ...

Technique traces origins of disease genes in mixed human populations

... said, to cover the whole genome. To tease out the origins of disease-causing genes, researchers use a technique called mapping by admixture linkage disequilibrium (MALD), a powerful approach to identify regions of the genome that have genes associated with disease. It takes advantage of ...

Genetic variants of USF1 are associated with the increased risk for cardiovascular disease

... the etiology of CVD are known, many are yet to be discovered. During the last few decades, scientists have searched for these genes with genome-wide linkage and association methods, and with more targeted candidate gene studies. Master of Science, Kati Kristiansson, from the research group of Professor ...

Marine scientists warn human safety, prosperity depend on better ocean observing system

... and interpret their evolutionary development; important opportunities exist for combining biological and physical data to better understand the linkage between marine ecosystems and ocean dynamics, says David Farmer, Fellow of the Royal Society and head of the University of Rhode Islands Graduate ...

Human safety, prosperity depend on better ocean observing system: Scientists

... and interpret their evolutionary development; important opportunities exist for combining biological and physical data to better understand the linkage between marine ecosystems and ocean dynamics, says David Farmer, Fellow of the Royal Society and head of the University of Rhode Islands Graduate ...

New genetic variant associated with prostate cancer in African-Americans

... cancer at Howard University Hospital in Washington, DC, and 567 African American men without cancer. The researchers were able to replicate the linkage between one of the markers detected by previous studies and increased risk. More important, they found a new genetic marker, known as rs7008482, ...

Study identifies genetic risk factor for rheumatoid arthritis, lupus

... also suggests a shared disease pathway for RA and lupus. "For this complex disease, rheumatoid arthritis, this is the first instance of a genetic linkage study leading to a chromosomal location, which then, in a genetic association study, identified a disease susceptibility gene," says Dr. Gregersen. ...

September Geology and GSA Today media highlights

... and desertification of equatorial Pangea. These model results are consistent with Late Paleozoic proxies of climate change, and imply a tight linkage between high- and low-latitude climate change. Short-term changes in seafloor character due to flood-derived hyperpycnal discharge: Typhoon ...

Does the desire to consume alcohol and tobacco come from our genetic makeup?

... were found inside the HTR2C gene for smoking. Conclusions According to Mr. Nikpay, the lead author of the research, We have found evidence of linkage and association for several genomic regions harboring genes with potential pathophysiological functions relating to alcohol and smoking. Our sex ...

Stanford-led study closes in on genes that may predispose some people to severe depression

... and DNA markers on the various chromosomes. The linkage study identified regions worthy of more intensive ... "We found highly significant evidence for linkage to depression in this particular part of ... he said. "This is one of the strongest genetic linkage findings for depression so far." "It's an ...
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