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Leucine in Biological News

Why the switch stays on

... of this amino acid to an amino acid called leucine is a commonly observed defect in cancer cells. ... and the defective Ras has position 61 as a leucine or one of the few amino acids shown to cause cell ... switch stays on when Raf binds Ras containing the leucine mutation and that it can be turned off in the ...

States expand newborn screening for life-threatening disorders

... in was part of a pilot program to expand newborn screening in California." 3MCC is a serious disorder that leaves newborns unable to metabolize leucine an essential amino acid found in many forms of protein. But because Giana, now age six, was diagnosed early, she was put on a special diet and is ...

Production of key Alzheimer's protein monitored for first time in humans

... give test subjects a form of the amino acid leucine that has been very slightly altered to label it. Inside the leucine are carbon atoms with 13 neutrons and protons in ... of hours, cells in the brain pick up the labeled leucine and incorporate it into the new copies they make ...

Feeling old?

... starts to win. However, adding the amino acid leucine to the diet of old individuals can set things ... that breakdown may be affected. While adding leucine to the diet restores protein building there was ... so there is excessive breakdown. But adding leucine to the diet restored a balanced metabolism. ...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

... changed." The change swaps the amino acid serine for the amino acid leucine at a key position in the protein. Serine can undergo phosphorylation, a form of chemical modification frequently used in biological processes; leucine cannot. This change apparently disrupts the processes that otherwise ...

Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life

... One of quirks of the genetic code is that there are groups of codons which all translate to the same amino acid. For example, the amino acid leucine can be translated from six different codons whilst some amino acids, which have equally important functions and are translated in the same amount, ...

Newly discovered genetic disease sheds light on body's water balance

... baby having a change from arginine to cysteine (R137C). This same mutation was carried by his mother. The other child had a change from arginine to leucine (R137L) but the mother is normal, suggesting that the baby's mutation occurred spontaneously. The fact that the two affected patients are boys is not ...
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