Common allergy drug reduces obesity and diabetes in mice
... and immune systemsin this case, controlling inflammation
in fat tissue. Fat tissue from obese and ... into the tissue. This can result in chronic inflammation
that causes asthma and certain allergies.
As ... an endocrinologist. "It's possible that the inflammation
caused by macrophages results in insulin ...
LSUHSC's Bazan awarded ARRA grant to preserve vision
... research project explores the mechanisms of inflammation
and repair during corneal wound healing. Sustained corneal inflammation
may lead to destruction and corneal ulceration, but inflammation
is a component of the corneal wound healing ...
Natural compound stops retinopathy
The discovery of the compound's function in inflammation
and blood vessel formation related to eye disease ...
Oklahoma researchers found that this inflammation
and leakage is caused by an imbalance of two ... in research models stopped the leakage, blocked inflammation
and kept unwanted blood vessels from growing. ...
New trigger for chronic inflammation in rheumatoid arthritis discovered
... to attack the joint leading to the persistent inflammation
of rheumatoid arthritis.
The molecular switch ... system and that these will reduce the painful inflammation
that is a hallmark of this condition," added Dr ... inflammation. The researchers induced joint inflammation
in mice with and without the gene for tenascin-C. ...
Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine
... their findings strongly correlate the severity of inflammation
associated with both Crohn's disease and ... used a mouse model of IBD, replicating inflammation
in the intestine like that in human ulcerative ... results indicate that meprin reduces the level of inflammation
in the injured intestine.
In the mouse model, ...
Omega fatty acid balance can alter immunity and gene expression
... this shift has brought about an increased risk of inflammation
(associated with autoimmunity and allergy), and ... agents, resulting in increased systemic inflammation
and a higher incidence of problems including ... found that many key signaling genes that promote inflammation
were markedly reduced compared to a normal diet, ...
MCG researcher among first to receive NIH stimulus funding
... that cocaine use, which can cause increased inflammation
and lead to heart and lung disease, might ... levels with blood levels of several inflammation
is linked to chronic stress, which poses another ...
Key protein regulating inflammation may prove relevant to controlling sepsis
... WIP1, as the molecular "brake" that curbs severe inflammation
in the body.
The findings may prove ... importance of WIP1 as an effective suppressor of inflammation
and explained how the body was able to cope with an excess of inflammation
brought on by the hyperactivation of the ...
Vitamin D deficiency related to increased inflammation in healthy women
... that low vitamin D levels negatively impact inflammation
and immune response, even in healthy women," said ... of Human Environmental Sciences. "Increased inflammation
normally is found in people with obesity or ... healthy women," was published in the Journal of inflammation
Gutsy germs succumb to baby broccoli
... also noted a greater than 50 percent reduction in inflammation
of the primary target of this bacterium the body ... of Nrf2 in protection against H. pylori -induced inflammation
Classified a carcinogen by the ... bacteria and blood tests to judge the severity of inflammation
in the stomach lining; in addition, they looked ...
UC Davis bench-to-bedside research: Promising treatment in clinical trials
... hypertension are often associated with vascular inflammation
as is atherosclerosis," Weiss said. "Last year we ... combined with the reduction of blood pressure, inflammation
and diabetes is very attractive."
The Phase ... failure and vascular inflammation." Vascular inflammation
is involved in diabetes and obesity side effects. ...
High-fat diets inflame fat tissue around blood vessels, contribute to heart disease
... inflamed, suggesting that they could trigger inflammation
of the blood vessels, an important component of atherosclerosis.
They also found that the inflammation
of fat tissues around the arteries of mice is ... a direct link between poor dietary habits and inflammation
of blood vessels, mediated by the fat cells ...
DNA component can stimulate and suppress the immune response
... way of eliminating invaders. But high doses block inflammation
by increasing expression of the enzyme ... the dosage can help them optimize the role of inflammation
in fighting invaders such as tumors and harmful ... Center, they've also learned IDO inhibits inflammation
by blocking production of interleukin 6, a ...
The quest for specific anti-inflammatory treatment
... molecule, they secrete molecules that generate inflammation
- prostaglandin and cytokine cells, for example. ... an anti-inflammatory function without causing inflammation
in other cells These analogues do not generate ... response to pro-inflammatory molecules.
Inflammatory processes may have ...
Uncultured bacteria found in amniotic fluids of women who experience preterm births
... the infection and inflammation.
is known to set off spontaneous births of preterm ... identify which germ is causing the infection and inflammation
leading to preterm birth so that antibiotics are ... it was not just one bacterial species causing the inflammation
but an abundance of different species in the ...
Tips from the American Journal of Pathology
New Candidate to Prevent inflammation
Dr. Sonia Oliani and colleagues at So Paulo ... issue of The American Journal of Pathology .
of the peritoneum is characterized by severe abdominal pain. This inflammation
can be prevented by annexin A1, which inhibits ...
Scientists find link between inflamed gums and heart disease
... for some time that a protein associated with inflammation
(called CRP) is elevated in people who are at risk for heart disease. But where's the inflammation
coming from? A new research study by Italian and ... observed a reduction in oral bacteria, immune inflammation
and the thickening of the blood vessels ...
LSUHSC research identifies key contributor to Alzheimer's disease process
... to be no more than a byproduct, in regulating inflammation
and the development of Alzheimer's disease. The ... that it plays a crucial role in the regulation of inflammation
and disease-related neuropathology thought to be ... amount and bioavailability of CFH, promoting the inflammation
of brain cells and contributing to the ...
Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease
... C-reactive protein (CRP), a central biomarker of inflammation
that has been shown to be a powerful predictor of ... a daily dose of vitamin C lowered levels of the inflammation
biomarker after two months compared with those ... percent of obese participants.
"The low-grade inflammation
that characterizes obesity is believed to ...
Drug-embedded microparticles bolster heart function in animal studies
... attack, the drug-embedded "microparticles" reduce inflammation
and scarring, the researchers found.
Injecting ... kinase, which is important during the damaging inflammation
that occurs after a heart attack.
Davis says ... to be broken down in the body, polyesters cause inflammation
exactly what the drugs are supposed to stop, he ...
Statins may prevent miscarriages
... (aPL) antibodies in female mice caused inflammation
that injured the placentas and induced abortions. ... a relationship between tissue factor and PAR2 in inflammation
that could have implications for understanding ... is a characteristic feature of acute and chronic inflammation
in conditions such as sepsis, atherosclerosis, ...
LIAI launches new division to look at novel approaches to heart disease and inflammation
... director of the Institute's recently launched inflammation
Biology Division. "We hope we can bite off ... a scientist of Dr. Ley's stature lead our new inflammation
Biology Division," he said. "Its creation puts ... immune-based approaches to heart disease, said inflammation
caused by the immune system is also an important ...
UC Davis researchers discover new drug target for inflammatory disease
... have defined a cellular process that promotes inflammation
and, at the same time, found an important ... impact of the finding on our ability to block inflammation
and stop the disease process in its tracks is ... another.
"We need to know the mechanisms of inflammation
to be able to disrupt it," said Takada. "Now that ...
Scientists suspect omega-3 fatty acids could slow acute wound healing
... health and other diseases related to chronic inflammation
because of their anti-inflammatory properties. But insufficient inflammation
during the initial stage of wound healing may ... associated with initiating and sustaining inflammation
were higher in the blister fluid in people who ...
Weill Cornell science briefs June/July 2008
... Crohn's Disease:
Stem Cells Heal Chronic inflammation
in the Gut
May Help Restore Immune System to ... the ability of the immune system to control inflammation
by secreting anti-inflammatory proteins into the ... immune response, leading to uncontrolled inflammation
in the tissues of the intestine. Diarrhea, ...
Failure to bridle inflammation spurs atherosclerosis
... the ability of blood vessels to recover from inflammation
atherosclerosis or hardening of the arteries can ... are produced in the blood vessel where the inflammation
occurs, the researchers said.
of the artery wall can cause atherosclerosis, a ...
New discoveries from Harvard and Baylor get to the heart of cardiovascular disease
... protein, called "ROCK1," profoundly reduces inflammation
in the walls of blood vessels provoked by fatty ... when they come into contact with fatty deposits. inflammation
is a normal byproduct of the clean-up process ... fatty deposits and mice showed significantly less inflammation
and atherosclerosis. This discovery could lead to ...
Early treatment of stomach infection may prevent cancer
... stages of progression from gastritis, an inflammation
of the mucous membrane layer of the stomach, to ... did not reverse the damaging changes, such as inflammation
and development of precancerous lesions, to the ... from the lower bowel and colonize it, producing inflammation
and progression to cancer, he said. . Findings ...
Inflammation triggers cell fusions that could protect neurons, Stanford research shows
... STANFORD, Calif. - Chronic inflammation
triggers bone marrow-derived blood cells to ... ulcerative dermatitis. This type of chronic inflammation
affects the entire immune system of the animal ... in the numbers of fused cells was related to inflammation
by using the traditional radiation/bone marrow ...
Nutrition research unveiled this week shows pistachios are smart for the heart
... cardiovascular health by significantly reducing inflammation
in the body, a prominent cardiovascular disease ... from all subjects and genetic expression of inflammation
markers was measured.
... a heart-healthy diet also significantly reduced inflammation
at the cellular level.
DFG to establish 10 new collaborative research centers
... (SFBs) will address a range of topics, including inflammation
of the brain, the distribution of oxygen in ... plan include an attempt to find out what role inflammation
plays in traumatic and neurodegenerative ... may be of great importance for use in inhibiting inflammation
or providing protection against viral infections, ...
HATS off to combat asthma
... that result in the symptoms of asthma and COPD inflammation
of the airways which can lead to coughing, ... is these transcription factors which activate the inflammation
by causing release of mediators and cytokines.
... and HDACs suppressed with the result that inflammation
is switched on. The investigators at the ...
Story ideas from the Journal of Lipid Research
... Progression of Atherosclerosis
While chronic inflammation
is a known risk factor for atherosclerosis ... have now shown that the sporadic but recurrent inflammation
caused by Crohns disease also poses serious ... than healthy individuals, revealing that acute inflammation
episodes not only reduce total HDL, but alter the ...
Nanoengineers mine tiny diamonds for drug delivery
... the paper, is that nanodiamonds do not cause cell inflammation
once the drug has been released and only bare ... present) and analyzed three genes associated with inflammation
and one gene for apoptosis, or cell death, to see ... circuitry of the cell, they found no toxicity or inflammation
long term and a lack of cell death. In fact, the ...
Story ideas from the Journal of Lipid Research
... that a lipid known to protect the heart from inflammation
and to cause skin allergic reactions also reduces inflammation
of the kidneys. The discovery could help devise ... responses that activate proteins that increase inflammation
and can even result in the death of the cell. UPR ...
Neuropathic pain: The sea provides a new hope of relief
... that this new compound could be a candidate.
Recent research suggests inflammation
in the nervous system is a major causative factor for this condition. inflammation
activates supporting cells, such as microglia and astrocytes, that ...
Scientists open doors to diagnosis of emphysema
... this test to samples of lung cells from a mouse model of acute lung inflammation
showed that MMP12 activity in macrophages was indeed increased.
... the new testing strategy can be extended to other enzymes involved in lung inflammation
and that, with a better picture of the processes underlying these ...
Scientists uncork a potential secret of red wine's health benefits
... of sepsis develop a very low quality of life due to the damage that inflammation
causes to several internal organs. The ultimate goal of our study was to ... inflammation. They found that resveratrol used a one-two punch to stop inflammation
in the mice by preventing the body from creating two different molecules ...
Placenta-derived stem cells may help sufferers of lung diseases
... cells as a therapeutic tool for disorders characterized by inflammation
and fibrosis is supported in previous studies," says Dr. Ornella Parolini, ... confer benefits for bleomycin-induced lung injury. While the severity of inflammation
did not show an overall reduction, there was a marked reduction in ...
Gene expression findings a step toward better classification and treatment of juvenile arthritis
... a diagnosis of JIA is imprecise and based largely on the presence of joint inflammation
persisting for at least six weeks, for which no other cause can be ... five or more joints), systemic arthritis (with fever and rash and inflammation
throughout the body) and enthesitis-related arthritis (affecting the ...