Immunization in Biological News

Scripps Research discovery leads to broad potential applications in CovX-Pfizer deal

... substrates.) "The key feature of the reactive immunization approach is that it allowed us to define in ... the antibodies the team developed with reactive immunization remain the most highly active catalysts ever ... too far behind. To illustrate the reactive immunization work during presentations to students and ...

Preventing ear infections in the future: Delivering vaccine through the skin

... in Philadelphia. "Our data are the first to show that transcutaneous immunization is an effective way to prevent experimental ear infections and lays the ... surface of this bacterium. Previous work in our lab showed that after immunization by injection, each of the three vaccine candidates prevented experimental ...

Children's National experts present at Pediatric Academic Societies' Annual Meeting

... Community Pediatric Health's award-winning approach to improving childhood immunization rates in Washington, DC. Jerome Paulson, MD, and Joseph L. Wright, MD ... during the PAS Annual Meeting for efforts that successfully raised the immunization compliance rates for young children (ages 19-35 months) in metropolitan ...

To fight the cancer before the tumor grows

... Researchers in Heidelberg have discovered a new strategy for an immunization against certain forms of cancer. They have determined that immune cells ... and strongly when cancer cells or their early stages appear. The new immunization strategy could be effective against 10 to 15 percent of all cancers. The ...

Texas Hospital nation's first to use large-scale 'cocoon strategy' against whooping cough

... Mary Healy, M.D., program leader and director of Vaccinology and Maternal immunization at the Center for Vaccine Awareness and Research. Through this program, ... said Dr. Melinda Wharton, deputy director of the National Center for immunization and Respiratory Diseases at the CDC. Not only will it benefit the families ...

Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants

... the flu vaccine, which will allow more people who need it to receive the immunization in a convenient and effective way," says Mark Prausnitz, PhD, a professor ... collaboration. Beyond influenza, the research could have implications for immunization programs in developing countries, where eliminating the use of hypodermic ...

More than half of Texas physicians do not always recommend HPV vaccine to girls

... PHILADELPHIA - The Advisory Committee on immunization Practices recommends the human papillomavirus vaccination for all 11- and 12-year-old girls, but results of a recent survey showed that more than ...

Tips from the journals of the American Society for Microbiology

... but also displayed cross-reactive immunity against the potentially pandemic H5N1 influenza virus. The researchers from the National Center for immunization and Respiratory Diseases, Collaborating Centers for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; and Novavax, ...

Cost-effective measures could stop child pneumonia deaths

... Implementing measures to improve nutrition, indoor air pollution, immunization coverage and the management of pneumonia cases could be cost-effective and significantly reduce child mortality from pneumonia, according to a study ...

Tips from the American Journal of Pathology

... and resident immune cells entered the blood stream after removing the dead cells. Joly et al suggest that this process may "enable an immunization against retinal proteins. Specific retinal proteins have long been used to induce ocular autoimmune inflammation. Future studies need to elucidate ...

New edition available for essential virology reference

... antiviral drug resistance, and threats of bioterrorism are balanced against improved insights into viral pathogenesis, better diagnostic tools, novel immunization strategies, and an expanding array of antiviral agents. The demands on clinicians, public health workers, and laboratorians will continue to ...

Vaccines and autism: Many hypotheses, but no correlation

... springs up to take its place," said study author Paul Offit, MD, of the Children's Hospital of Philadelphia. Fears about vaccines are pushing down immunization rates and having a real impact on public health, he added. Vaccine refusal is contributing to the current increase in Haemophilus influenzae cases ...

New breastfeeding study shows most moms quit early

... article Are US Mothers Meeting the Healthy People 2010 Breastfeeding Targets for Initiation, Duration, and Exclusivity? The 2003 and 2004 National immunization Surveys published in the August issue of the Journal of Human Lactation (published by SAGE). The article is available for free for a limited time ...

Mesothelin engineered on virus-like particles provides treatment clues for pancreatic cancer

... span for the mice not treated was four weeks. The immunized mice survived five weeks longer than those not treated. Researchers found that the immunization works by suppressing production of key immune system cells that suppress the bodys ability to fight the tumor. The researchers said pancreatic ...

An Alzheimer's vaccine?

... Could a new vaccine be the key to stopping Alzheimers disease" A new research study from the Oklahoma Medical Research Foundation (OMRF) shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease. OMRF scientists immunized Alzheimers mice with a protein believed ...

AIBS to cohost symposium on evolution, disease and human health

... senior investigator in the Meningitis and Vaccine Preventable Diseases Branch of the Division of Bacterial Diseases at the National Center for immunization and Respiratory Diseases of the Centers for Disease Control and Prevention, will give a presentation titled The Race between Bacterial Adaptation and ...

Needle-free immunizations

... has estimated that as many as one-third of immunization injections are unsafe in four of it six ... because of the development costs of new immunization methods, use of needle-free immunization might initially push the direct cost of ...

New Vaccine To Be Used For First Time In Polio Outbreak Response

... the planning for appropriate supplementary immunization activities. Four cases of polio were confirmed ... across the affected governorates in Yemen. Low immunization rates among Yemen's children may facilitate the ... Use of mOPV1 is expected during a nationwide immunization campaign in the second half of May. Yemen had ...

Fragile US vaccine system needs improvement despite dramatic gains in health over past century

... faces additional challenges posed by the adult immunization program, the need for adequate research and ... global health; Lance Rodewald, director of the immunization Services Division in the National immunization Program at the U.S. Centers for Disease Control ...

Measles Deaths Worldwide Drop By Nearly 40% Over Five Years

... The strategy seeks to achieve routine measles immunization coverage of at least 90% in every district and to ... age receives a "second opportunity" for measles immunization through routine services or supplementary immunization activities (SIAs) every three to four years. The ...

High-dose flu vaccines appear to safely boost immunity in elderly

... about serious adverse events or side effects. Blood was drawn before the immunization and one month after. On average, individuals who received higher ... dose than among those who received the 15 ìg dose, most reactions to the immunization were mild. Although current vaccines are sufficient to protect younger ...

HIV vaccine takes different tack to boosting immune response

... off were more efficient at stimulating the body's immune cells. Most immunization attempts to stimulate an immune response to HIV in the past have been ... both antibody and T-cell response by inhibiting SOCS1." Chen hopes this immunization approach of inhibiting SOCS1 will help develop more effective prophylactic ...

Congenital rubella syndrome nearly eradicated in the US

... whose mother had been born in the U.S. The remarkable success of the immunization program to eliminate rubella is due to joint efforts by the Centers for ... the March of Dimes, according to the statement. Maintaining high rubella immunization rates is crucial to the continued success of these efforts. The statement ...

Mice studies illustrate potential of chimp/human antibodies to protect against smallpox

... the Proceedings of the National Academy of Sciences (PNAS). A worldwide immunization program officially eradicated naturally occurring smallpox disease in ... virus, a relative of the variola virus that causes smallpox. Vaccinia immunization has been proven effective in generating immunity against smallpox virus ...

Hospitalizations because of chicken pox down dramatically since implementation of vaccine

... August 17 issue of JAMA. Varicella vaccine is recommended for routine immunization of children aged 12 to 18 months and for older susceptible children and ... previously been limited. Fangjun Zhou, Ph.D., M.S., of the National immunization Program, Centers for Disease Control and Prevention, Atlanta, and ...

Active Vaccine Prevents Mice From Developing Prion Disease

... is important because it breaks new ground in demonstrating that active immunization can protect a significant percentage of animals from developing symptoms ... and the lead author of the study. The vaccines that provide active immunization are made, in part, from proteins found on disease-causing organisms. In ...

Norovirus, AIDS vaccine and Hepatitis Virus

... Extensive testing has been conducted with live vaccines to determine if immunization would be effective at prevention, but they are not suitable for human use ... without the need for booster doses with viral proteins, for large-scale immunization programs," say the researchers. (D.K. Singh, Z. Liu, D. Sheffer, G.A. ...

Progress toward an antitumor vaccine

... to the carrier protein in a controlled fashion. The largely nonimmunogenic thioether bridges could clear the way for the development of vaccines for immunization against tumor cells.” ...

Genetic factors are linked to fever following smallpox vaccination

... implications for predicting adverse events from other live vaccines. immunization against infectious agents has been one of the greatest successes of modern ... considered by some to be the crowning event of the 20th century. However, immunization with live virus particles, as in the smallpox vaccine, can sometimes cause ...

New vaccine prevents CMV infection and disease in mice

... Christopher S. Morello, Ph.D., first author of the study. To do this, the researchers devised a vaccine with a one-two punch that combines a DNA immunization that targets T-cells to essential genes required for CMV replication, with a killed virus that prompts the body’s B-cells to generate an antibody ...

New study suggests potential for a broadly-protective HIV vaccine

... the immunizations to determine their effectiveness in neutralizing the infectivity of a variety of HIV-1 strains. Antibodies produced as a result of immunization neutralized all 48 strains of HIV-1 tested. The results are encouraging for vaccine development, because they showed that it is possible to elicit a ...

Thymus transplants gives hope to babies with fatal immune disease

... it or not, later this month Dave'yana, because of her new immune system, gets to experience what other children her age face -- standard childhood immunization shots. ...

NIAID expands capability for influenza research and surveillance

... surveillance system that will monitor selected communities in New York for seasonal flu virus infections, and will study the effectiveness of annual immunization programs using inactivated or weakened (live, attenuated) flu virus vaccines. The Rochester center also will perform clinical immunological studies ...

Mechanisms involved with tumor relapse identified

... strategies to fight a number of cancers. Immunotherapy involves the manipulation of the immune system ?by introducing an antibody or lymphocytes, or immunization with a tumor vaccine ?to recognize and eradicate tumor cells. Using a transgenic mouse model of breast cancer, researchers found that ...

Billions of dollars saved in US by polio vaccination

... saving Americans hundreds of billions of dollars in treatment costs. Dr. Stephen Cochi, U.S. Centers for Disease Control and Prevention Global immunization Division Senior Advisor and an expert on polio said, "This study documents the extraordinary power of vaccines not only as highly effective tools to ...

CSHL research ties harmless viruses to cancer

... and inactivating these viruses would help to decrease the incidence of the disease. This prognosis is consistent with the successes of preventative immunization against hepatitis B and papilloma viruses, which both cause cancer. Lazebnik and his CSHL colleague Dominik Duelli estimate that at least 18 of 29 ...

What does the public really know about HPV?

... approved the first vaccine to prevent infection of two high risk types of HPV, and two types that cause genital warts. The Advisory Committee on immunization Practices (ACIP) recommended it for females 9 to 26 years of age. Two studies presented today at the American Association for Cancer Research's ...

Jefferson researchers building a better rabies vaccine

... "We have identified a molecular mechanism involved in making the rabies virus pathogenic and lethal, and have developed a very safe vaccine for the immunization of wildlife," says Bernhard Dietzschold, DVM, professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson University in ...

New Rotavirus vaccine joins routine infant immunization schedule

... and The Wistar Institute are co-inventors of the vaccine, based on research dating to 1980. Meeting today in Atlanta, the Advisory Committee on immunization Practices (ACIP), an expert panel selected by the U.S. Department of Health and Human Services, added the new RotaTeq vaccine, manufactured by Merck ...