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Hypothalamic in Biological News

How appetite-stimulating brain cells work overtime during fasting

... UCP2, which is present at high levels in the hypothalamic arcuate nucleus--considered to be the key brain ... hypothalamus that fat levels have fallen, leading hypothalamic neurons to activate a program, including hunger, ... and colleagues] have elegantly demonstrated that hypothalamic responses to food deprivation involve at least ...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

... how Hap1 is linked to feeding-related molecules such as insulin, and to hypothalamic neuronal function," said Xiao-Jiang Li, PhD, professor of human genetics ... "Scientists know that diabetes and obesity are related to abnormalities of hypothalamic function," Li said. "This is a complicated pathway, and Hap1 can help us ...

Study by Einstein researchers could lead to a novel strategy for treating obesity

... a molecule suspected of being one of the critical nutrients influencing hypothalamic regulation of eating behavior. Previous studies had shown that hypothalamic levels of malonyl CoA increase markedly after meals and are suppressed by ...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

... of the research team. The compound - JV-1-36 - is an antagonist of the hypothalamic growth hormone- releasing hormone, which has been found to cause cancerous ... such as malignant glioblastomas, to grow. The main known purposes of the hypothalamic growth hormone-releasing hormone usually are to trigger the hormone that ...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

... by the hypothalamus, such as feeding. Di says that the "actions of the endocannabinoids on the synaptic circuits that control the activity of the hypothalamic neurons serve to rapidly inhibit hormone secretion from the pituitary gland, providing a rapid negative feedback mechanism for the regulation of ...
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(Date:7/9/2014)... developed by researchers at the NIH,s National ... its collaborators to treat sickle cell disease ... business. The drug candidate, Aes-103, is the ... molecular mechanism of sickle cell disease. Baxter ... required for regulatory approval and commercialization. , ...
(Date:7/9/2014)... receptor antagonists can alleviate the symptoms of ... cognitive dysfunction and effectively scavenge amyloid beta ... (Aβ) vaccines reduced and eliminated Aβ deposition ... model, and significantly improved behavioral and cognitive ... First Affiliated Hospital of China Medical University, ...
(Date:7/9/2014)... inhabitants of the sea: tiny haptophytes of the type ... eye, when they are in bloom in spring, they ... on satellite images. "Together with other phytoplankton, Emiliania ... global photosynthesis output," states Prof. Dr. Georg Pohnert of ... the greenhouse gas carbon dioxide CO2 is ...
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(Date:7/9/2014)... ITHACA, N.Y. Although feelings are personal and ... standard code that objectively represents emotions across different ... study by Cornell University neuroscientist Adam Anderson. , ... within the orbitofrontal cortex, an area of the ... neural code which captures an individual,s subjective feeling," ...
(Date:7/9/2014)... have been linked to an emerging fungal disease ... Institute for Mathematical and Biological Synthesis (NIMBioS) shows ... , In a series of mathematical models, researchers ... internal organs in frogs, could cause extinction of ... exposed to the virus every few years, a ...
(Date:7/9/2014)... the most important organs in the human body. Its ... properly this is its synthesis function and ... this is its detoxification function. Lack of exercise and ... the liver. The resulting diseased cells can lead to ... failure. According to the German Liver Foundation, over five ...
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(Date:7/8/2014)... longevity and cardiovascular health as other healthy mature individuals, ... American Journal of Transplantation . The findings may provide ... transplant professionals caring for them. , Over the past ... years and older has become more common. Given the ... the removal of a kidney could make older donors ...
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