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Hyperactivity in Biological News

History of hyperactivity off-base, says researcher

... children a disservice by claiming that hyperactivity as we understand it today has always existed. ... Medical History at the University of Exeter. hyperactivity disorder, or ADHD, is currently the most commonly ... at Ottawa's Carleton University this week, that hyperactivity disorder as we understand it today is a modern ...

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

... whose groundbreaking research on conduct disorder and attention deficit hyperactivity disorder has led to new understanding of these conditions and improved ... led to improved diagnostic criteria, and has validated the distinction of hyperactivity from conduct disorder. His longitudinal epidemiological studies have ...

Researchers develop 'brain-reading' methods

... plan to develop a system for identifying neural connectivity abnormalities to assist with the study of such mental disorders as attention-deficit hyperactivity and autism and to produce a handbook for many of the new tools used for pattern analysis and the classification of mental states based on ...

Gene discovery could lead to male contraceptive

... very vigorous hyperactive motion the sperm uses when it is entering the egg during fertilization. "Our research suggests that the defect in sperm hyperactivity that is seen in mice without CATSPER1 will also occur in humans with the genetic mutation," Hildebrand said. "Identification of targets such as the ...

Fetal alcohol syndrome testing expands

... imaging) facility to measure differences in brain activity in children with developmental disorders such as FASD and ADHD (Attention Deficit hyperactivity Disorder). They are building a database of task performance and brain functioning across many clinical populations. "This is very exciting ...

Studies examine genetic determinants of ADHD

... ADHD is a complex condition with environmental and genetic causes. It is characterized by developmentally inappropriate levels of inattention, hyperactivity and impulsivity that has an onset in childhood. It is one of the most common psychiatric diseases, affecting between 8-12 percent of children ...

Promising new drug being evaluated as possible treatment option for fragile X syndrome

... pediatric neurologist at Rush and principal investigator of the study. "Also, some patients showed calmed behavior and rapid reduction in hyperactivity and anxiety, similar to effects of the drug in mouse models." Fragile X syndrome is the most common inherited cause of mental impairment and the ...

Singapore research team first place in Brain-Computer Interface contest

... such as a communication platform for paralyzed patients, rehabilitation for stroke patients and the treatment for children with Attention-Deficit hyperactivity Disorder. For more information about Singapore's BCI technology: http://www.i2r.a-star.edu.sg/enews/technology/bci.htm During the ...

M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan

... suspected, potentially affecting over one million men, women and children in the United States. The premutation can cause attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder in children; primary ovarian failure (early menopause) in women; and FXTAS, or fragile X- associated ...

Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system

... affect "normal" mice. Looking more closely at this phenomenon, the researchers write, "could be useful in understanding the causes of human hyperactivity such as that observed in ADHD." "This technique also gives researchers the power to activate dopamine neurons selectively," says Lester. "We plan ...

News tips from the Journal of Neuroscience

... Sitte, Aurelio Galli, and Randy D. Blakely Elevated dopamine efflux through the dopamine transporter may underlie some forms of attention-deficit hyperactivity disorder (ADHD), according to Mazei-Robison et al. The authors identified a mutant form of dopamine transporter in two siblings with ADHD and ...

Did the gene for ADHD help our nomadic ancestors?

... codes for a receptor for dopamine, one of the chemical messengers used in the brain. Previous research has linked the gene with Attention Deficit hyperactivity Disorder-type behavior in young men risk-taking, reward-seeking and impulsivity, says Campbell. But people can have different versions of the ...

Court Approves Scheme of Arrangement

... commercialization including, but not limited to, the establishment in the market of VYVANSE(TM) (lisdexamfetamine dimesylate) (Attention Deficit and hyperactivity Disorder ("ADHD")); the impact of competitive products, including, but not limited to, the impact of those on Shire's ADHD franchise; patents, ...

Prions show their good side

... Their neurons responded longer and more vigorously to electrical or drug-induced stimulation than did neurons that had normal prion protein. This hyperactivity eventually led to the neurons death. The results might help explain why misfolded prions cause dementia: in the wrong conformation, the prion can no ...

Negligent, attentive mouse mothers show biological differences

... mothers did successfully raise some of the pups born to previously nurturing mothers, but these surviving pups showed lasting effects, including hyperactivity and low adult body weight. Some females neglected as youngsters were also poor mothers as adults, suggesting some aspects of neglect can be ...

NJIT start-up company NeuroTrax named best in show

... and the early detection of Alzheimers disease. The software program can also be used for early detection of Parkinsons disease, attention deficit hyperactivity disorder, multiple sclerosis, schizophrenia, and traumatic brain injury. Mindstreams has been established in 23 peer-reviewed scientific ...

Adolescent girls with ADHD are at increased risk for eating disorders, study shows

... Girls with attention deficit hyperactivity disorder stand a substantially greater risk of developing eating disorders in adolescence than girls without ADHD, a new study has found. ...

Effective ADHD treatment found for children with fragile X syndrome

... Fragile X syndrome (FXS) is the most common hereditary form of mental retardation. Many children with FXS also suffer from attention deficit and/or hyperactivity disorder (ADHD), which complicates social relationships at home and at school. Although stimulant medication such as Ritalin is often successfully ...

MSU researcher helps develop computer game for Ugandan children recovering from cerebral malaria

... EAST LANSING, Mich. The computer program Captains Log originally used with individuals diagnosed with attention deficit hyperactivity disorder, brain injuries or learning disabilities is being adapted to rehabilitate Ugandan children who are survivors of cerebral malaria. ...

Insulin's brain impact links drugs and diabetes

... drug abuse, the findings raise questions as to whether improper control of insulin levels as in diabetes may impact risk for attention deficit hyperactivity disorder (ADHD) or influence the effectiveness of current ADHD medications. The study, led by Aurelio Galli, Ph.D., in the Center for Molecular ...

A new kind of rat model

... impairments that we saw in one consomic strain are similar to some of the symptoms that you see in human children with autism or attention deficit hyperactivity disorder (ADHD), Swain says. Test results so far have shown that some of the consomic rats exhibited increased depressive-like behavior, increased ...

Restless legs syndrome affects nearly 2 percent of US/UK children

... unless he or she met all of the other diagnostic criteria for RLS. Some parents are surprised to learn that conditions such as attention deficit hyperactivity disorder and depression appear to be more common in those diagnosed with RLS. Sleep disturbance, by itself, is known to aggravate ADHD and ...

Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions

... stimulant aids people with attention deficit and hyperactivity disorders to improve their focus without ... mostly in children, to treat attention deficit hyperactivity disorder (ADHD) and attention deficit disorder ... disorder, a similar condition but one in which hyperactivity isn't a symptom. They also want to know ...

Racing neurons control whether we stop or go

... which helps explain the impulsivity of people with attention deficit and hyperactivity disorder," study co-author Jeffrey Schall, E. Bronson Professor of ... task times are significantly longer in children with attention deficit and hyperactivity disorders than in other children," he said. The model has been widely ...

Unraveling a stomach cancer puzzle

... cancers are similar to those we would predict if the same thing, Stat3 hyperactivity shutting down TGF, happens in humans. So this is also the first time a ... of stomach and other cancers. "We've demonstrated that by lowering Stat3 hyperactivity we can suppress stomach cancer formation, importantly without affecting ...

Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

... sleep is notable; it may be part of the reason why mood-disturbed pregnancies are linked to childrens behavioral disorders, like depression, hyperactivity and anxiety, later on down the road, OConnor said. It remains to be seen if the sleep problems we witnessed may play an active, causal role in ...

Prenatal cocaine's lasting cellular effects

... cognitive and emotional development." These children often exhibit attention and arousal problems, similar to children with attention deficit hyperactivity disorder (ADHD). However, the standard treatments for ADHD -- Ritalin and other stimulants -- are not always effective in these children. ...

Sleep disturbances affect classroom performance

... said Pagel. Both restless legs and difficulty concentrating during the day are symptoms associated with the diagnosis of Attention Deficit hyperactivity Disorder (ADHD), a diagnosis that can be associated with poor school performance. It is important for parents to discuss their teen’s sleep-related ...

Brain networks strengthened by closing ion channels

... of drug therapies for the cognitive deficits of normal aging, and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder (ADHD). "Our data reveal how the brain's arousal systems influence the cognitive networks that subserve working memory-which plays a ...

Cocaine high caused by interference in neuronal receiving stations

... The researchers also analyzed whether this interaction between D2R and NR2B affected the rats' behavioral response to cocaine—specifically the hyperactivity and intensive sniffing and biting the drug elicits in the animals. They found that drugs that either activated the D2R subunit or inactivated the ...

High dopamine transporter levels not correlated with ADHD

... with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dopamine transporter" proteins in ...

Mutant mice show key autism traits

... in nest-forming and sexual and maternal behavior. In tests of their reaction to such sensory stimuli as bright environments, the mutant mice showed hyperactivity and increased anxiety. They also showed sporadic seizures. The researchers concluded that "the mutant mice exhibited deficits in all social ...

Study reveals how ADHD drugs work in brain

... Although millions depend on medications such as Ritalin to quell symptoms of attention deficit hyperactivity disorder (ADHD), scientists have struggled to pinpoint how the drugs work in the brain. But new work at the University of Wisconsin-Madison is now ...

Engineered mouse mimics cognitive aspects of schizophrenia

... this most malignant of mental disorders," wrote Snyder. Kellendonk and his colleagues based their experiments on a widely accepted theory that hyperactivity in the brain's dopamine machinery plays a central role in schizophrenia. Dopamine is a major neurotransmitter in the brain--a chemical messenger that ...

Recreating 'Flowers for Algernon' with a happy ending

... needed by the brain to record learned information." The UCLA team began searching for a safe drug that would zero in on Ras and overcome its hyperactivity without causing harmful side effects over long-term use. "It became something of a Quixotic quest -- an impossible dream," Silva admitted. "We ...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

... on the brain. Normally associated with triggering feelings of pleasure, excess concentrations of dopamine underlie schizophrenia, attention deficit hyperactivity disorder and other psychiatric conditions. The findings therefore provide new research avenues to understand and potentially manage such ...

Beyond lithium for bipolar disorder

... found throughout the central nervous system, said the researchers. They cited studies demonstrating that mice in which the gene is knocked out show hyperactivity and defects in their circadian (day-night) behavior--both also characteristic of humans with bipolar disorder. Also, in animals, lithium has been ...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

... nerve cell development--knowledge that may one day provide clues about such neurological mysteries as autism spectrum disorder or attention deficit hyperactivity disorder. To test her hypothesis, MBL scientist Carol Reinisch and her colleagues treated developing surf clam embryos (Spisula solidissima) ...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

... nerve cell development--knowledge that may one day provide clues about such neurological mysteries as autism spectrum disorder or attention deficit hyperactivity disorder. To test her hypothesis, MBL scientist Carol Reinisch and her colleagues treated developing surf clam embryos (Spisula solidissima) ...
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