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Human in Biological News

La Jolla Institute discovers novel tumor suppressor

... his research team got similar results in tests of human cells from people with Burkitt's lymphoma, an ... disease," he said. "We also have done human cell testing in some other lymphomas and ... other tumors. And, of course, its application in human disease needs further study. But we hope other ...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

... engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. ... researchers successfully tested the antibody in human glioblastoma cells, and also showed that in mice implanted with human glioblastoma, the antibody prevented tumors from ...

Rodent size linked to human population and climate change

... at Chicago ecologist has tied these changes to human population density and climate change. The ... islands to those from the mainland, where human populations were denser. Pergams found both ... of the 15 traits were associated with changes in human population density, current temperature, or ...

Reprogramming human cells without inserting genes

... a novel way to turn on stem cell genes in human fibroblasts (skin cells) without the risks ... eventually lead to treatments for a range of human diseases and traumatic injuries by coaxing a ... "Induction of Stem Cell Gene Expression in Adult human Fibroblasts without Transgenes," published online ...

Stem cell research: From molecular physiology to therapeutic applications

... for generating a wide range of different human cells that can be used to restore malfunctioning ... which has been studied in both animal models and human patients for more than 20 years. Recent progress ... a mesenchymal stem cell (MSC) population from human fetal bone marrow and found that these cells ...

First genetically-engineered malaria vaccine to enter human trials

... at least 35 million years of healthy, productive human life every year. Professor Alan Cowman, head of ... to multiply and lead to disease," he said. The human trials of the vaccine will take place at the ... manufacturing practice guidelines required for human clinical trials. ...

Maternal, paternal genes' tug-of-war may last well into childhood

... to that parent. "Compared to other primates, human babies are weaned quite early, yet take a very ... and paternal genes may skirmish over the pace of human development." Previous research has offered ... past childbirth. "This analysis suggests that human life history, and especially humans' unusual ...

Researchers team up to provide new hope for childhood hunger

... mechanisms by which malnutrition compromises human health, gaining new scientific insights to ... that contain all the necessary nutrients for human health in appropriate amounts could very well ... nutrition and use of plant science to enhance human health. Raise awareness in public and ...

Humans lend a hand to critically endangered waterbird

... human impact on one of the world's most threatened bird ... a fascinating outcome as we tend to assume that human activity always has a negative impact on the natural world." Not all human influence is positive for the endangered ibis, ...

Protein that promotes cancer cell growth identified

... A number of cell death proteins are missing from human tumors, allowing cancer cells to ignore the cues ... advantage. However, this is rarely observed in human cancers. By providing a more complete ... intervention point for treating multiple types of human cancers. ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... of the cell, have been implicated in a variety of human disorders, including cancer," says Jared Rutter, ... and then moved on to study its potential role in human disease." Sdh5 is a mitochondrial protein that ... of yeast Sdh5 is 44 percent identical to its human counterpart, which we've named hSDH5. This gave ...

Salt marshes: A natural and unnatural history

... toxic waste, and mistreated for centuries by the human population. Exploring the fascinating ... the importance of these habitats, consequences of human neglect and thoughtless development, and insight ... writer and photographer, shed ample light on the human impact of the marsh lands. SALT MARSHES includes ...

Skin-like tissue developed from human embryonic stem cells

... at Tufts have harnessed the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues that mimic human skin and the oral mucosa (the moist tissue that ... tissues are remarkably similar to their human counterparts and can be used to address major ...

C. difficile spores spread superbug

... a 'mouse hospital' with conditions mimicking the human environment in which C. difficile is ... C, before reintroduction and infection in a new human host. "We treated mice with short and longer ... The bacterium can live inside the gut of healthy human beings, existing as part of a natural, diverse ...

University of Miami receives stimulus funds for study of hurricane impacts on structures, ecosystems

... standards and practices designed to protect human lives and enhance resiliency. The National ... the connections between the oceans and human health including studies of harmful algal blooms, ... as well as developing aquatic animal models of human diseases such as neurodegeneration. ...

Reviews of microbial gene language published in special issue of Trends in Microbiology

... many genes discovered by these initiatives. The human Microbiome Project (HMP), for example, plans to extensively sequence the metagenomes of five human body sites and look for correlations between microbial communities and human health. Dr. Michelle Giglio, Assistant Professor ...

The last supper of the hominids establishes the times they lived at the sites

... has allowed the establishment of the length of human occupations at archaeological sites. The key is ... by researchers from the Catalan Institute of human Paleoecology and Social Evolution (IPHES) in ... allows us to establish the relative length of the human occupations at archaeological sites as, up until ...

Mystery E. coli genes essential for survival of many species

... world remains an enigma that may hold the key to human diseases, such as cancer. The team, funded by ... case of one of the genes it is also found in the human genome, which makes it especially interesting. ... involved in cell division. ygjD is present in the human genome and also appears to be the key player of ...

New study ranks 'hotspots' of human impact on coastal areas

... ecosystems are at risk worldwide as a result of human activities, according to scientists at UC Santa ... waters must address a litany of impacts from human activities, from the land, such as urban runoff ... pollutants from urban runoff direct impact of human populations on coastal marine habitats. ...

Springer to collaborate with the Human Genome Organization

... The HUGO Journal in cooperation with the human Genome Organisation (HUGO). Formerly published ... clinical and population explorations of the human genome and genomes of organisms relevant to human health. The journal will publish primary ...

Data published in the New England Journal of Medicine support use of raxibacumab (ABthrax) for the treatment of inhalation anthrax

... ROCKVILLE, Maryland July 9, 2009 human Genome Sciences, Inc. (Nasdaq: HGSI) today ... showed the life-saving potential of the Company's human monoclonal antibody drug raxibacumab (ABthrax), as well as the results of human safety studies, which supported the use of ...

Plastics chemical retards growth, function of adult reproductive cells

... activity on these cells, Flaws said. human studies have found BPA in many tissues and ... Program of the U.S. Department of Health and human Services concluded in 2008 that while BPA has ... gland in fetuses, infants and children at current human exposures to bisphenol A." The new study ...

Fish on the menu of our ancestors

... "Carbon and nitrogen isotope analysis of the human and associated faunal remains indicate a diet ... an expanding population at the time of modern human emergence across Eurasia. "This analysis provides ... in China and has implications for early modern human subsistence and demography", says Richards. ...

First cGMP feeder-independent pluripotent stem cell banks released for distribution

... to researchers worldwide. These cGMP banks of human embryonic stem (ES) cells are produced using H9 ... and the most frequently used and cited human ES cell line in stem cell research today. Release ... produced from newly derived, fully compliant human ES cells and induced pluripotent stem (iPS) ....

Dogs, humans, put heads together to find cure for brain cancer

... Pinpointing the genes involved in human brain cancer can be like looking for a needle in ... you find may not be the right one. By comparing human and canine genomes, researchers at North Carolina ... affect the meninges, or thin covering, of the human brain and account for one out of four adult brain ...

Research network wins approximately £5.7 million to target human and animal diseases in Africa

... humans and animals, including new infectious human diseases of animal origin. SACIDS will ... approach, which promotes collaborations between human and animal health sectors. The link between ... and important sector. Most major infectious human diseases have animal origins and up to 80 per ...

Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research

... His work has had a remarkable impact on human health and truly embodies the efforts of the ... early 1980s, he developed genetically engineered human insulin, the first therapeutic derived from gene ... discovered gene with an oncogenic function in human cancer. In the early 1990s, Ullrich identified ...

NIST issues human milk and blood serum SRMs for contaminant measurements

... need to measure organic contaminants in human body fluids, the National Institute of Standards ... for Disease Control and Prevention (CDC), the human milk and serum SRMs have certified levels of ... SRM (SRM 1589 Polychlorinated Biphenyls in human Serum) in 1985 to aid with the detection of ...

Chromosomal problems affect nearly all human embryos

... Evelyne Vanneste, a PhD student in the Centre for human Genetics and the University Fertility Center, ... 25th annual conference of the European Society of human Reproduction and Embryology today (Wednesday July ... embryos are the most representative of normal human embryogenesis, the process that begins once an ...

Will IVF work for a particular patient? The answer may be found in her blood

... 25th annual conference of the European Society of human Reproduction and Embryology today (Wednesday 1 ... by the constantly changing expression of human genes." Previous studies in the field of ... as opposed to genome-wide screening of all the human genes with high density DNA microarrays, as used ...

Single thawed embryo transfer after PGD does not affect pregnancy rates

... 25th annual meeting of the European Society of human Reproduction and Embryology in Amsterdam and ... Europe's leading reproductive medicine journal, human Reproduction, simultaneously today (Tuesday). ... cycle again." The first author of the paper in human Reproduction, Dr Tarek El-Toukhy, a consultant in ...

Purple sweet potato means increased amount of anti-cancer components

... K-State's Soyoung Lim, doctoral student in human nutrition, Manhattan, is working with George Wang, associate professor of human nutrition at K-State, to understand the pigment ... effects of cyanidin and peonidin. Lim treated human colon cancer cells with low concentrations of the ...

New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis

... Netherlands: A new test examining chromosomes in human eggs a few hours after fertilisation can identify ... 25th annual conference of the European Society of human Reproduction and Embryology today (Monday 29 ... The incidence of chromosomal abnormalities in human eggs is closely related to maternal age, and can ...

Female human embryos adjust the balance of X chromosomes before implantation

... unknown in humans, does, in fact, take place in human female embryos prior to implantation in the womb. ... 25th annual meeting of the European Society of human Reproduction and Embryology in Amsterdam today ... Due to the difficulties of investigating XCI in human embryos (because of the shortage of embryos ...

New trigger for chronic inflammation in rheumatoid arthritis discovered

... A signal molecule made by the human body that triggers the immune system into action ... that cause inflammation. The researchers took human immune cells called macrophages and cells called ... these levels of inflammatory molecules in the human joint and try to find ways to inhibit this ....

Scripps Research scientists observe human neurodegenerative disorder in fruit flies

... and walking difficulties. After the human genome was solved a few years ago, studies ... mutations in their genes that make a critical human protein called tyrosyl-tRNA synthetase. This ... a condition with several of the hallmarks of the human disease. This suggests that Charcot-Marie-Tooth ...

NYU Langone Medical Center awarded NIH grants totaling $1,560,000

... NIH Roadmap for Medical Research as part of the human Microbiome Project (HMP) taking place at ... live in and on our bodies affect our health. The human microbiome is all the microorganisms that reside in or on the human body, as well as all their DNA, or genomes. ...

A Canada-wide technology platform for mapping the human interactome

... national technology platform aimed at mapping the human interactome. This national platform, headed by ... integrated infrastructure for deciphering the human interactome an expertise that, until now, has ... 12 universities across Canada. Sequencing the human genome has revolutionized biomedical research. ...

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

... The human Microbiome Project has awarded more than $42 ... of Health (NIH) announced today. The human microbiome is all the microorganisms that reside in or on the human body, as well as all their DNA, or genomes. ...

DNA template could explain evolutionary shifts

... ) , vice chair of molecular and human genetics at BCM and senior author of the report. ... variation involves structural changes in the human genome that result in the deletion of genes or ... wrote a new chapter in the understanding of human genetic variation. In a previous report ...
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