Women often opt to surgically remove their breasts, ovaries to reduce cancer risk
... always happen immediately after counseling or a genetic
test result and can take more than seven years ... for surgery within the first two years after the genetic
mutation test, but some did not make a decision ... in a very comprehensive and well thought-out genetic
counseling, testing and management program," said ...
Abnormal brain circuits may prevent movement disorder
... MANHASSET, NY -- Most people who carry a genetic
mutation for a movement disorder called dystonia ... that has puzzled scientists since the first genetic
mutation was identified in the 1990's. Now, ... of a specific abnormality in people with the genetic
mutation who never develop symptoms could ...
Understanding how weeds are resistant to herbicides
... Illinois weed scientist Patrick Tranel got more genetic
information about waterhemp than in two years time in a lab. The genetic
information was obtained using pyrosequencing technology in the Keck Center at the U of I. The genetic
sequence will allow scientists to study herbicide ...
Parasites ready to jump
... Transposons are mobile genetic
elements found in the hereditary material of ... (a class of nucleic acid closely related to the genetic
material DNA) play the central role. "Transposons ... one or more genes, make up as much as half of the genetic
material. "This demonstrates", says Frstemann, ...
Little-known protein found to be key player
... protein previously implicated in a rare genetic
disorder plays an unexpected and critical role in ... of hereditary spastic paraplegia (HSP), the genetic
disorder that atlastin has been linked with," Daga said.
HSP is a rare genetic
condition that affects fewer than one million ...
Maternal, paternal genes' tug-of-war may last well into childhood
... Mass., July 28, 2009 -- An analysis of rare genetic
disorders in which children lack some genes from ...
Previous research has offered evidence of a genetic
struggle for supremacy only during fetal ... and paternal genes continue to engage in internal genetic
conflict past childbirth.
"This analysis ...
'Corrective genes' closer thanks to enzyme modification
... its discovery as it sought ways to help correct genetic
diseases. "Our goal is to improve the injection of corrective genes in people suffering from genetic
diseases," say Pelletier who is also co-director ... this insight to further advance therapies for genetic
diseases such as leukemia."
Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
... leukemia (AML) found only a few mistakes in the genetic
blueprint, suggesting the cancer arises from just ... that the development of AML may require fewer genetic
alterations than other cancers and that a very ... cell into a cancer cell. "The complement of genetic
lesions varies across the ...
Scientists discover gene mutation responsible for hereditary neuroendocrine tumor
... out by human hSdh5," explains Rutter. "Previous genetic
studies have shown that the hereditary ... three patients with PGL2.
Implications on genetic
The identification of hSDH5 as the ... for patients with familial PGL syndromes. genetic
testing is suggested for the management of PGL, ...
Genetic tests advertised directly to the consumer
... Singapore and Washington DC (July 20, 2009) genetic
testing services have recently begun to be ... "Direct-to-Consumer/Patient Advertising of genetic
Testing: A Position Statement of the American ... there's no comparable supervision for advertised genetic
testing. In order for the consumer to have a ...
Iowa State University researchers develop process for 'surgical' genetic changes
... has resulted in a process that will make genetic
changes in plant genes much more efficient, ... an assistant scientist, and allows targeted genetic
manipulations in plant DNA, which could have a huge impact on plant genetic
work in the future.
Until now, when scientists ...
Researchers gain insight into mechanism underlying Huntington's
... Toxicology (GCT) have gained new insight into the genetic
mechanisms underlying Huntington's disease and ... involved in the development of a specific type of genetic
mutation known as trinucleotide repeat ... Gu are coauthors of the study.
"Mutations the genetic
changes in DNA can lead to many different types ...
2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award
... Institute Early Career Scientist.
Malik studies genetic
conflict. He sees battles raging within a cell's ... to study the causes and consequences of these genetic
conflicts in yeast, fruit flies and other model ... Ph.D., he first became intrigued by the study of genetic
conflict. Malik joined the Hutchinson Center ...
Dogs, humans, put heads together to find cure for brain cancer
... the skull. In humans, they are associated with genetic
defects of large segments of chromosomes, which ... of genomics at NC State.
"With so much genetic
material to consider, one can see why figuring ... same kinds of cancers. While we share much of our genetic
material, the DNA of a dog is organized ...
New national genome center launched
... in genomics - the science of understanding the genetic
makeup of organisms and the genetic
differences that exist between individuals. This ... of some cancers. Better understanding of the genetic
mechanisms underlying the synthesis of these ...
... making certain plants resistant to the GFLV by genetic
engineering. "Our modified plants produce ... have to modify its genotype and channel genetic
information for the antibodies into it. This task ... by tiny helpers called agrobacteria, which genetic
engineers have been using for over twenty years. ...
Chromosomal problems affect nearly all human embryos
... that current techniques used in preimplantation genetic
screening (PGS), where embryos are screened ... fertile couples who had asked for preimplantation genetic
diagnosis (PGD). PGD is carried out where one or both parents have a known genetic
abnormality, in this case an X-linked disorder or ...
Anti-biotech groups obstruct forest biotechnology
... one of the world's leaders in the application of genetic
science to forestry.
"Everyone wants safe and ... make it virtually impossible to move ahead with genetic
modification in forestry or woody energy crops. ... including the United States. By contrast, genetic
modification studies in forest trees take longer, ...
New test can detect both genetic and chromosomal abnormalities in embryos
... The Netherlands: One-step screening for both genetic
and chromosomal abnormalities has come a stage ... gene mutation using conventional preimplantation genetic
Gary Harton, PGD scientific ... universal method for analysing the inheritance of genetic
defects in the preimplantation embryo without any ...
Single thawed embryo transfer after PGD does not affect pregnancy rates
... womb after embryos have undergone preimplantation genetic
diagnosis (PGD) and freezing at the blastocyst ... centres to include PGD cycles for inherited genetic
disorders in their efforts to reduce the multiple ... embryo transfer policy to PGD for inherited genetic
disorders because of concerns about how well ...
Working to conserve endangered 'Playboy' bunnies
... adapt to new conditions depends on the variety of genetic
information present in natural populations. The more genetic
diversity a species has, the greater its rate of survival is.
"The loss of genetic
diversity can have long-term repercussions by ...
Further gene mutations linked to autism risk
... (CHOP). The study identified 27 different genetic
regions where rare copy number variations ... common neurodevelopmental syndromes with a strong genetic
component. ASDs are characterized by disturbances ... poorly understood.
The researchers compared genetic
samples of 3,832 individuals from 912 families ...
T-STAR grant funds genetic studies on shrimp and papaya and endangered cycad rescue
... researcher with WPTRC, was awarded $186,960 for a genetic
variability study of specific pathogen free (SPF) ... a panel of species-specific microsatellite genetic
markers. Says Dr. Gong, "The long term research objective is to establish a medium-scale, effective genetic
selection program of P. vannamei on Guam to ...
Genetic finding could lead to targeted therapy for neuroblastoma
... GAINESVILLE Researchers have identified a genetic
glitch that could lead to development of ...
To do this, researchers analyzed the genetic
makeup of 846 patients with neuroblastoma, whose ... the bigger picture, an understanding of the genetic
mechanisms that lead to neuroblastoma," said ...
NIH expands Human Microbiome Project; funds sequencing centers and disease projects
... environmental factors, diseases and a woman's genetic
J. Dennis Fortenberry, M.D., Indiana ... It will also study the influence of human genetic
variation on the composition of the microbiome. ... the intestinal microbiome and disease subjects' genetic
factors to uncover relationships with Crohn's ...
Prostate Cancer Translational Research in Europe meeting: Search for biomarkers continues
... work regarding the identification of common genetic
variants that affect the risk of prostate cancer. 42% of prostate cancer has a genetic
cause. The lifetime risk of a man in the European ... Rafnar said as she added that "the search for genetic
determinants of disease severity is ongoing."
DNA template could explain evolutionary shifts
... a critical point and then shifts to a different genetic
template, duplicating and even triplicating genes ... cell that results from the division has the same genetic
code. That means it must replicate its DNA. ... strand, an enzyme called DNA polymerase reads the genetic
material in the strand as a template and makes a ...
Domestication of Capsicum annuum chile pepper provides insights into crop origin and evolution
... the number of times it was domesticated, and the genetic
diversity present in wild relatives.
To answer ... locations is not significantly influencing genetic
diversity, in contrast to maize and beans seeds, ... traded by farmers across long distances. Less genetic
diversification was seen in wild populations of ....
Chemical in blood may explain susceptibility to bladder pain
... by pregnant females might transmit to fetuses a genetic
change associated with the stress response.
Buffington suggests that such a genetic
change would mean offspring born to these mothers might then have a genetic
predisposition to be more vulnerable to certain ...
Aussie and Kiwi researchers make double MS genetic discovery
... discovery reveals important new insights into the genetic
susceptibility to the disease, "says Professor ... Kilpatrick.
"They also reveal a link between genetic
susceptibility to MS and other autoimmune ... human genome in broad brushstrokes; looking at genetic
landmarks in the genome and then progressively ...
Work of Field Museum scientist addresses question of chance in evolution
... very long spans of time, the major channels of genetic
organization, organism form, and the different ... that given the possibilities afforded by time, a genetic
background would arise (like flipping a coin long ... the eventual realization of a particular genetic
and developmental channel, and natural selection ...
Researchers identify new risk factor gene for rheumatoid arthritis
... arthritis (RA). The hope is to figure out the genetic
triggers and identify treatments that block this ... genes involved in rheumatoid arthritis but this genetic
finding is significant because of its key role in ... regulation. It did not reveal itself in previous genetic
studies because the sample size was just not ...
Amarna Therapeutics B.V. and TNO announce SVac research and development partnership
... address the major diseases of our time including genetic
disorders, autoimmune diseases, allergies and ... allergies and cancer and gene therapies to treat genetic
disorders. The base of Amarna’s ... system known that is suitable for for treating genetic
disorders and immunity associated diseases.
Recruitment of reproductive features into other cell types may underlie extended lifespan in animals
... of Molecular Biology have found that certain genetic
mutations known to extend the lifespan of the C. ... accomplish this feat, in part, by adopting genetic
programs normally restricted to the germline into ... researchers discovered that simple mutations in genetic
pathways conserved throughout evolution can ...
USC researchers present diabetes findings at American Diabetes Association Scientific Sessions
... type 2 diabetes and related traits focusing on genetic
variants in genes involving the pancreatic beta cell.
changes may result in diabetes. Next steps in genetic
research, follow-up on initial findings, and the ...
Geography and history shape genetic differences in humans
... contractions of populations, and the vagaries of genetic
chance have heavily influenced the distribution of genetic
variations in populations around the world. The ... researchers found that many previously identified genetic
signals of selection may have been created by ...
Tulane receives grant to study limb regeneration
... to injuries in mice who, because of their similar genetic
characteristics, serve as a model for humans.
"The hope is that once the genetic
signals for regeneration are identified, ... a salamander limb, we will essentially create a genetic
blueprint of how to do the same in humans."
Genetically corrected blood cells obtained from skin cells from Fanconi anemia patients
... of blood cells from skin cells of patients with a genetic
disease known as Fanconi anemia. The process is ... that, for the first time, in the case of a genetic
disease such as Fanconi anemia it is possible to correct the genetic
defect in patient-specific skin cells by ...
Penn researchers discover genetic risk factor for testicular cancer
... heritable, there really have not been any clear genetic
risk factor that can account for most cases of ... Center. "These variants are the first striking genetic
risk factors found for this disease to date."
... is intriguing and may reflect the impact of the genetic
effect of KITLG," Kanetsky says. "However, since ...
International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury
... results from its research designed to discover genetic
markers that may predict individuals at risk for ... hypothesis that many of these differences have a genetic
basis. Its research studies are exploring the ... DILI is unknown, research suggests a genetic
In a Nature Genetics paper ...