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Fragment in Biological News

UMMS researchers publish DNA identification of czar's children

... bloodstain DNA profile for all DNA systems matched with that of the bone fragment DNA profiles, and so we could conclude the identity of the putative ... of Y- chromosome markers demonstrated further the link between the bone fragment of putative Alexei to his father Tsar Nicholas II and the distant paternal ...

A simple fusion to jump-start evolution

... to be the same size, but the efficiency of the reactions was dependent on fragment size (larger is better, though efficiency drops again after reaching around 100) and the similarity of the fragment sequences. The researchers note that this spontaneous fusing, or ...

Researchers coat titanium with polymer to improve integration of joint replacements

... and bone with the titanium implants coated with the engineered fibronectin fragment over the uncoated or RGD-coated titanium. Garca and Petrie tested the ... mechanical fixation of the implants coated with the engineered fibronectin fragment over the implants with the other coating and uncoated titanium. In ...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

... could theoretically bind. We found just the right one." They collaborated with ESBAtech in Switzerland who created a small single-chain antibody fragment in yeast that would itself bind to the sweet spot, blocking ALK's interaction with PTN. In the present study, the researchers successfully tested the ...

Sex in the Caribbean: Environmental change drives evolutionary change -- eventually

... forms are unmistakable," explained O'Dea. "You can clearly see the first individual that founded a sexual colony, while a clonal colony preserves the fragment from the previous colony from which it cloned." As predicted, clonal bryozoans rapidly disappeared from the record as the Caribbean was isolated. ...

The tiny difference in the genes of bacteria

... for every bacterial strain. To identify a certain strain, the HZI researchers use short DNA fragments, marked with certain dyes. Each dyed DNA fragment recognizes a single tandem repeat, binding at it. As a result, the researchers receive, for example, six red fragments binding a tandem of six ...

Nursery programs for corals receive TLC from NOAA this Independence Day

... and nursery fragments have already been used to restore four reefs where staghorn corals were depleted. The proposed plan includes expansion of fragment stocks (up to 4,000 fragments at this site) and the restoration of eight additional reefs over the next three years. Florida boasts one of the ...

The tiny difference in the genes of bacteria

... for every bacterial strain. To identify a certain strain, the HZI researchers use short DNA fragments, marked with certain dyes. Each dyed DNA fragment recognizes a single tandem repeat, binding at it. As a result, the researchers receive, for example, six red fragments binding a tandem of six ...

Slicing chromosomes leads to new insights into cell division

... Using newts as a model organism, they cut off pieces of the chromosomes' arms. "We asked what the relationship is between the size of the fragment we removed and the direction the chromosome moved," Hunt said. "Not only did we observe a relationship, we established that polar ejection forces ...

New insights into progressive hearing loss

... have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. The new gene - called a microRNA - is a tiny fragment of RNA that affects the production of hundreds of other molecules within sensory hair cells of the inner ear. The research provides important new ...

New technique used to profile anthrax genome

... B. anthracis cells growing in a variety of conditions. They collected more than 270 million sequence "tags," each of which corresponds to a short fragment of an RNA molecule, and pieced them together using a custom software tool that they developed for the project. "Once the data were together, it ...

Musicians have biological advantage in identifying emotion in sound

... Study participants were asked to watch a subtitled nature film to keep them entertained while they were hearing, through earphones, a 250-millisecond fragment of a distressed baby's cry. Sensitivity to the sound, and in particular to the more complicated part of the sound that contributes most to its ...

Tailor-made recombinant proteins in mammals

... near sites that, if modified, would cripple the antibody instead of making it therapeutic. Bertozzi's group proved they could precisely tag the Fc fragment of the IgG molecule so that it would selectively bind with chemicals engineered to react with the aldehyde. The Fc fragments were the only proteins ...

Complete Genomics releases proof-of-concept data for its sequencing technology for the first time

... were able to call alleles for both parental chromosomes for 91 percent of the genome. Sequencing this remaining fraction of DNA will require our Long fragment Read (LFR) technology addition that is currently being implemented." "In a draft assembly, we discovered the expected 3.3 million ...

January-February GSA Bulletin media highlights

... data from these tonalites suggest that they formed from the melting of the volcano-sedimentary package. This old, crustal sequence may be a fragment of the Earth's earliest continental crust. Postorogenic shoshonitic rocks and their origin by melting underplated basalts: The Miocene of ...

Scientists study how asbestos fibers trigger cancer in human cells

... the research at the American Geophysical Union meeting in San Francisco. Asbestos comprises six different minerals that naturally occur in both fragment and fibrous forms. Because of its high durability and heat resistance, the fibrous form has been used in many manufacturing products since the late ...

LSUHSC research identifies key contributor to Alzheimer's disease process

... and Ophthalmology at LSU Health Sciences Center New Orleans, is the lead author of a paper identifying, for the first time, a specific function of a fragment of ribonucleic acid (RNA), once thought to be no more than a byproduct, in regulating inflammation and the development of Alzheimer's disease. The ...

How we see objects in depth: The brain's code for 3-D structure

... objects as spatial configurations of surface fragments, something like a structural drawing. Individual neurons are tuned to respond to surface fragment substructures. For instance, one neuron from the study responded to the combination of a forward-facing ridge near the front and an upward-facing ...

Pectin power

... possible explanation for why people who eat more fruit and vegetables may gain protection against the spread of cancers. They have shown that a fragment released from pectin, found in all fruits and vegetables, binds to and is believed to inhibit galectin 3 (Gal3), a protein that plays a role in all ...

Human Microbiome Project awards funds for technology development, data analysis and ethical research

... years); Assembly and Analysis Software for Exploring the Human Microbiome Yuzhen Ye, Ph.D., Indiana University, Bloomington; $770,000 (3 years); fragment Assembly and Metabolic Species Diversity Analysis for the Human Microbiome The NIH also awarded a cooperative agreement of approximately $9.9 ...

New blood test for Down syndrome

... technology and equally powerful computers to identify millions of unique sequence "tags" in the fetal DNA. Each of these tags was a 25 base-pair fragment of DNA. After the tags were identified, Quake's group could then map them to specific locations on the 23 pairs of chromosomes. By using this ...

October 2008 GEOLOGY and GSA TODAY media highlights

... on the Indian Ocean floor off southwestern Australia and find evidence that a large submarine mountain range, the Naturaliste Plateau, is a fragment of an older supercontinent called Rodinia. This piece of crust formed over a billion years ago and is probably related to similarly aged rocks now ...

Thumbs up -- a tiny ancestral remnant lends developmental edge to humans

... was not to produce mice with human fingers. Rather, an indirect assay was employed to test the expression readout of a single human genetic fragment and compare it with the chimp version. The strategy, which links a color-inducing reporter gene when expression is activated, turns the targeted ...

World's smallest snake found in Barbados

... discovery will be published on 4 August 2008 in the journal Zootaxa . Hedges found the new snake -- a type of threadsnake -- in a tiny forest fragment on the eastern side of Barbados. He believes the species is rare because most of its potential habitat has been replaced by buildings and farms. ...

Let the cat keep chasing the mouse

... They have been strolling through the forests of Europe since ancient times on their soft velvety paws and certainly long before mankind started to fragment the forest with his axe or before the Romans brought their domestic cats with them from North Africa. Indeed, the wildcat looks very similar to our ...

August 2008 Geology and GSA Today media highlights

... during a geological survey provides evidence of the oldest human presence yet discovered along the northernmost margin of Egypt's Nile delta. A rock fragment carried by humans to the site was discovered in a sediment core section north of Burullus lagoon near the Mediterranean coast. Radiocarbon analysis ...

UT pathologists believe they have pinpointed Achilles heel of HIV

... work of Dr. Paul's group is highly innovative. They have identified antibodies that, instead of passively binding to the target molecule, are able to fragment it and destroy its function. Their recent work indicates that naturally occurring catalytic antibodies, particularly those of the IgA subtype, may ...

Great Ape Trust's Wich lead author of Oryx paper on continuing orangutan population declines

... depend on them for survival. For example, in Sumatra, the controversial Ladia Galaska road project in the Leuser Ecosystem will, unless halted, fragment two of the three largest remaining orangutan populations, Wich et al. wrote. A similar project in 1982 split the Gunung Leuser National Park, and the ...

NJIT doctoral students receive recognition at poster competition

... American Mixing Forum Conference. Caramellino of Nutley presented her research project, in which she explained how she used a high shear device to fragment micro particles. Her research was also presented last November at the AIChE meeting. Next fall, both students will travel to Boca Raton, all ...

Scientists determine drug target for the most potent botulinum neurotoxin

... deadly effects prior to exposure. The scientists did not work with intact Clostridium botulinum bacteria. Instead, they produced a functional fragment of the neurotoxin protein, which is not toxic. The research is performed in strict compliance with Brookhavens Institutional Biosafety Committee ...

Genetic Engineering & Biotechnology News reports on growing use of cell-based assays

... protein-protein interactions. DiscoveRx created a new family of cell-based assays for the detection of protein-protein interactions using an enzyme fragment complementation assay. This system uses an enzyme acceptor, an inactive alpha-galactosidase enzyme that binds to its enzyme donor forming an active ...

Researchers close in on origins of main ingredient of Alzheimer's plaques

... process, known as endocytosis, in a mouse model of Alzheimer's disease. The change led to a 70 percent drop in levels of amyloid beta, the protein fragment that clumps together to form Alzheimer's plaques. Importantly, they also found that endocytosis' ability to increase amyloid beta was coupled to ...

Satellites take sustainability to new heights

... to Shell, the images allowed them to monitor vegetation, track land use changes, capture roads, power lines and other installations that can fragment habitat. They also provide them with the capability to establish baseline environmental information before developing new areas. Based on EO ...

A fossilized giant rhino bone questions the isolation of Anatolia, 25 million years ago

... in Anatolia. Discovered in 2002 during a Franco-Turkish paleontology expedition in the region of ankiriorum (Central Anatolia, Turkey), the bone fragment from the forearm (radius) described by the scientists measures 1.20 meters long and probably belonged to a very large male (about 5 meters to the ...

Moss protein plays role in Alzheimer's disease

... to arbitrate functions during development. Two genes occur in mammals in which mutations cause an earlier onset of Alzheimers. One is APP, where a fragment of the protein accumulates in amyloid plaques, associated with the disease. Another common site for mutations is found in presenilin (PS) proteins. ...

Carnegie Mellon scientists develop fluorescent proteins for live cell imaging, biosensor design

... selective biosensor for proteins at the outside of the cell surface. The FAP is a specialized single chain antibody (scFv), a recombinant fragment of full-size antibody proteins that the human immune system uses to identify intruders like bacteria or viruses. The Carnegie Mellon scientists ...

Prostate cancer: Watchful wait or vaccinate?

... and tested it in 8-week-old mice that were genetically altered to develop prostate cancer later in life. The first vaccine simply delivered a fragment of DNA that coded for PSCA, thus producing an influx of PSCA protein to alert the immune system. The booster shot, given two weeks later, used a ...

Researchers reveal HIV peptide's possible pathway into the cell

... cells. The theorists analyzed two years of biocomputation and simulation to uncover a surprisingly simple mechanism describing how this protein fragment penetrates the cell membrane. The discovery could help scientists treat other human illnesses by exploiting the same molecules that make HIV so ...

New route for heredity bypasses DNA

... is, that would take a DNA molecule of the ciliate's consisting of, for example, pieces 1-2-3-4-5 and transpose two of the segments, to produce the fragment 1-2-3-5-4. Injecting their synthetic templates into the developing cell produced the anticipated results, showing that a specified RNA template could ...

Ant invaders eat the natives, then move down the food chain

... to a need for more long-term studies of native and non-native species, Suarez said, rather than the more common, short-term studies, which see only a fragment of the bigger puzzle. The way the invasive species are interacting with the environment might actually be changing over time, Suarez said. Only ...
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(Date:7/11/2014)... Evidence exists that cannabinoid receptor type 1 ... Ca2+ influx, and reduce neurotransmitter release. However, ... 1 can increase extracellular Ca2+ influx and ... his team, Tongji Hospital Affiliated to Tongji ... Technology, China used whole cell voltage-clamp and ...
(Date:7/10/2014)... , June 27, 2014  The American ... National Institute of Standards and Technology (NIST) and ... its academic research and forensic science expert members ... Board is an element of the NIST,s Organization ... are among the first appointments made to the ...
(Date:7/10/2014)... , July 2, 2014 It is a ... announce the appointment of the world-renowned Thoracic and Cardiovascular ... Directors. Dr. Ginsburg, with over 34 years ... Presbyterian Hospital and Good Samaritan Regional Medical Center. Dr. ... the late 1980,s and is considered an expert in ...
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