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Error in Biological News

Scientists compiled 20th century temperature data in Spain as evidence of climatic change

... criterion. Despite this, the instrumental error in a temperature measurement is in the order of 0.1C, and the error of a difference between data, previously treated ... method, rises to the order of 0.4C. This error is not negligible but anyway it is considerably ...

The Burnham Buzz, February 2009

... The conventional approach to finding drug combinations involves trial and error testing. Gaining Control Burnham scientists have identified the ... controlling the S-phase of the cell cycle. If damaged DNA or a replication error is identified, Ddk acts as a quality control protein and stops replication ...

Flying off course

... the vagrant birds end up in the wrong wintering areas as a result of an error in their migratory programme. Since many questions still remain unanswered ... way down the migration flyway The scientists suspect the cause is an error in the genetic migratory programme. The flight direction and flight ...

Poll Shows Strong Doubts About Effectiveness of Federal Employment Verification System

... informed that E-Verify relies on a government database with a 4 percent error rate, which could mean as many as 6 million citizens and other legal ... January 10-16, 2008. The results are subject to a margin of sampling error of approximately plus or minus three percent. The survey was conducted on ...

New folic acid seal helps women choose enriched grain foods to help prevent birth defects

... A sample this size yields a 95% confidence level with a margin of error +/- 4.1%. When using the sub-quotas of 300, the data has a 95% confidence level with a range of error of +/- 5.5%. ...

After dinosaurs, mammals rise but their genomes get smaller

... against excess DNA. An LTR is far more likely to survive a few years of cell divisions -- and the chance of obliteration via a DNA replication error -- than 10 million years of cell divisions. Plotting the full range of 17 species' LTRs, young and old, Lynch and his colleagues usually saw a ...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

... fusions, specific to certain types of prostate cancer, may help physicians prescribe tailored therapies for their patients by avoiding the trial and error that is often associated with cancer treatments," says Dr. Rubin, who is also the associate director of translational research and a pathologist at ...

New research shows dinosaurs may have been smaller than we thought

... data, and creates biases that can affect the predictive results obtained from the equation. Birchard and his colleagues realized there was an error when they used the equation to determine the weight of living animals such as a hippopotamus and an elephant and discovered that the equation greatly ...

Molecular typesetting -- proofreading without a proofreader

... is always incorporated at the right spot. "Statistically, we would expect to see a hundred-fold more errors than we actually do, so we know that some error correction must be happening. Otherwise, many more proteins in our bodies would malfunction," says Dr Cohen. Biological experiments have shown ...

Rules proposed to save the world's coral reefs

... in the Bohol Sea in the Philippines, the Great Barrier Reef in Australia, and Kimbe Bay in Papua New Guinea. These rules are: allow margins of error in extent and nature of protection, as insurance against unforeseen threats; spread risks among areas; aim to create networks of protected areas ...

Study validates means to measure possible leukemia marker

... changes and the severity of CLL. To verify the accuracy of their measurements, the investigators tested the technology against common sources of error that can arise in clinical testing laboratories. These included analyzing samples prepared in different ways and by different people, and using ...

Landfill cover soil methane oxidation underestimated

... of soil covers ranged from 22% in clayey soil to 55% in sandy soil. The overall mean fraction oxidized across all studies was 36% with a standard error of 6%. For a subset of fifteen studies conducted over an annual cycle the fraction of methane oxidized ranged from 11 to 89% with a mean value of 35 ...

Learning how the pieces responsible for interpreting the human genome work

... in disease and cancer tissues. "Most diseases arise as a result of the incorrect functioning of DNA proteins. For example, cancer is always an error or an accumulation of errors in DNA caused by the improper work of proteins that should protect, repair or read it". According to Thomas Gingeras, ...

CSHL scientists clarify editing error underlying genetic neurodegenerative disease

... Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia (PCH). The new findings were published online, ahead of print, on January ...

HWI scientist first in world to unravel structure of key breast cancer target enzyme

... the structure was not known, nor the mechanism of androgen to estrogen conversion, the AIs currently in use have been developed using trial and error methods resulting in greater vulnerability to contraindications and side effects. "Now that the Ghosh Lab has unraveled the molecular details of ...

Lost in translation

... them react to lab-induced chemical errors and were surprised to see that the protein-manufacturing process didn't proceed as usual, getting past the error and continuing its "walk" along the DNA's protein-encoding genetic messages. "We thought that once the mistake was made, it would have just gone ...

BioScience tip sheet, January 2009

... engineers. Understanding this complexity can help allocate water within the Okavango watershed. Spurious Certainty: How Ignoring Measurement error and Environmental Heterogeneity May Contribute to Environmental Consequences. Reinette Biggs, Stephen R. Carpenter, and William A. Brock. ...

NIST guides genetic genealogy labs toward improved accuracy

... it is considered likely that they share a common ancestor. Accurately counting the number of repeats is a tricky task and the source of much of the error in genetic genealogy tests, causing genealogists to make incorrect matches or miss family connections altogether. In their paper, the NIST ...

VCU survey: US public supports genetic research, testing and government spending on research

... VCU Life Sciences Survey, in its eighth year, was conducted by telephone with 1,005 adults nationwide, from Nov. 24 to Dec. 7, 2008. The margin of error for the poll is plus or minus 3.8 percentage points. This is the eighth annual VCU Life Sciences Survey, conducted for VCU Life Sciences and the VCU ...

Irritable bowel syndrome can have genetic causes

... in the intestinal tract and thus slows the movement of the bowels. "Currently, patients with irritable bowel syndrome are treated on a trial and error basis"", explains Dr. Beate Niesler. The Heidelberg data could contribute to development and prescription of specific medications for certain genetic ...

Using water to understand human society, from the industrial revolution to global trade

... a European Science Foundation and COST conference in Sicily in October, Tvedt proposed that social scientists and historians have long made a serious error by not taking natural resources into account in their attempts to understand social structures. Water, according to Tvedt, is a unique natural ...

Candy-coating keeps proteins sweet

... for extended periods of time. Pharmaceutical companies, though they have general guidelines, develop their formulations essentially by trial and error and have to wait up to two years to see if the glasses are suitable. The new methods will help pharmaceutical companies make the best choice about ...

Ultrasonic frogs can tune their ears to different frequencies

... ultrasonic sounds, and can localize sound with astonishing precision. Upon hearing a female call, a male will leap directly toward the sound with an error of less than 1 percent, a feat previously unheard of in frogs. Fortunately for the researchers, the eardrum of O. tormota is transparent, ...

Digital cameras, remote satellites measure crop water demand

... and linearly related with measured CC across the wide range of crops, canopy structures, and growth stages, and predicted CC with mean absolute error of 0.047 up to effective full cover. These results indicate that remotely sensed NDVI may be an efficient way to monitor growth stage, and ...

Killer whales, blind bats, discriminating dolphins, mating birds

... distance from the bat have zero ranging errors, while ranging errors increase for closer or more distant objects. This distance of zero ranging error depends on signal design, in particular the sweep rate, according to Holderied. By adjusting signal design, flying bats could shift this distance ...

Fat: Its not what you think!

... and health, a conception that Professor of Medicine and Biochemistry at Vanderbilt University George Mann, MD, calls the greatest biomedical error of the twentieth century. Dr. Mann elaborates, For fifty years the public has been told by officials of the American Heart Association and the ...

Fraud attempt in a paternity test modifies action protocol in DNA tests

... journal of the American Academy of Forensic Sciences . The reason is obvious: It raises the need of adopting special measures to prevent experts error leading to crime or fraud or lack of punishment. From this publication, many protocols of saliva taking for forensic analysis (cases of paternity, ...

Virtual human in HIV drug simulation

... a course of drugs and then test whether these are working by analysing the patients immune response. One of the goals of VPH is for such trial and error methods to eventually be replaced by patient-specific treatments tailored to a persons unique genotype. Professor Peter Coveney says: This study ...

Biophysical Society announces winners of 2008 Student Travel Awards

... University, Molecular Mechanism of Phospholipid Transfer by Lipid Transporter Protein Sec14p. Hao Chen, Purdue University, Predicting the error of Template-Based Protein Structure Modeling by Suboptimal Alignment Stability. Logan R. Chieffo, Boston University, Vibrational Lifetime of ...

Widespread support for nonembryonic stem cell research, VCU Life Sciences Survey shows

... of this years nationwide survey conducted by VCU via telephone with 1,000 adults nationwide from Nov. 26, 2007, to Dec. 9, 2007. The polls margin of error is plus or minus 3 percentage points. The survey is conducted for VCU Life Sciences and the VCU College of Humanities and Sciences by the VCU Center ...

RNA interference therapy heals growth deficiency disorder in a live animal

... growth but actually killed the cells in the pituitary that produce growth hormone. This came as a real surprise: We never thought that a splicing error would lead to cell death, says Patton. Meanwhile, progress in RNA interference research gave Patton and Phillips an idea for a way to correct this ...

Scientists complete genome sequence of fungus responsible for dandruff, skin disorders

... made possible by DNA sequencing technologies developed within the last decade. Scientists previously tested many different compounds in a trial and error style to find ways to treat and reduce dandruff symptoms. In fact, due to the earlier use of less-accurate culture-based technologies, scientists ...

Weizmann Institute scientists discover: A 'risk distribution law' for evolution

... In other words, the level of risk appears to written in the genetic code, in a way thats similar to financial risk analysis: When the cost of error is high, an investors willingness to chance the risk is low, but if the cost of a mistake is negligible, even if the chance of making one is high, ...

US fires release large amounts of carbon dioxide

... by Wiedinmyer, that estimates carbon dioxide emissions based on the mass of vegetation burned. They caution that their estimates have a margin of error of about 50 percent, both because of inexact data about the extent of fires and varying estimates of the amount of carbon dioxide emitted by ...

Israeli scientists identify: Genes that affect responses of multiple sclerosis patients to copaxone

... (MS) by Teva, which produces and markets Copaxone® today. 'Until now, medical treatments for all kinds of diseases have relied on trial and error methods to determine dosage and treatment protocols,' says Prof. Ariel Miller of the Ruth and Bruce Rappaport Faculty of Medicine at the Technion, ...

Majority of Americans want local action on global warming, says poll

... Population Survey on sex, age, region, and education. The final sample is considered to be representative of U.S. adults nationwide, with a margin of error of /- 3 percentage points. ...

Discovery may help defang viruses

... West Nile Virus for developing vaccines. "All standard approaches for vaccine development take years," said Cameron. "It is all a random trial and error process to get an attenuated weakened virus that may be treated as a potential vaccine candidate. There is no direct method." Positive strand RNA ...

Innovative civil engineering application promises cleaner waters

... optimal BMPs for a particular location. This technique is expected to drastically reduce the BMP selection time and will also eliminate the human error from such a complex process, says project coordinator Tamim Younos, water center associate director and research professor of water resources in the ...

Finding that 1-in-a-billion that could lead to disease

... at Hopkins. But the question is how these enzymes find the few mistakes among the billions of correct building blocks in DNA. One typical error that occurs is to the DNA building block cytosine, being chemically converted to a similar-looking building block not normally found in DNA: uracil. ...

New caledonian crows find 2 tools better than 1

... toolbox and the long stick was handy. The crows then briefly probed the box containing the short stick with the long stick before correcting their error by taking the stick directly to the hole. "It was surprising to find that these 'bird-brained' creatures performed at the same levels as the best ...
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(Date:7/24/2014)... similar counterparts in humans, affect the connections between nerve ... the hippocampus, an area of the brain that plays ... of memories. The results of the study have been ... function depends on the active communication between nerve cells, ... together into a dense network where they constantly relay ...
(Date:7/24/2014)... 24, 2014) For years, researchers and patients have ... any cell type in the bodycould provide insight into ... Yet progress has been hampered by the inability to ... their human counterparts, in part because human ESCs are ... , Now Thorold Theunissen, Benjamin Powell, and Haoyi Wang, ...
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