Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

... the compound for the treatment of acute hepatic encephalopathy (AHE). The compound recently demonstrated ... has the potential not only to improve symptoms of encephalopathy but may also help to reverse this ... significant unmet clinical need to treat hepatic encephalopathy which affects 40-60 percent of patients with ...

Experimental treatment halts hypoxic-ischemic brain injury in newborns

... be a promising therapeutic target in infants suffering hypoxic-ischemic encephalopathy (HIE). Identification of a treatment target is a vital step to finding better ways to treat newborns with HIE. "Not only is hypoxic-ischemic encephalopathy an important cause of perinatal mortality and permanent neurological ...

K-State professor's USDA research shows mad cow disease also caused by genetic mutation

... Richt said, it was thought that the cattle prion disease bovine spongiform encephalopathy -- also called BSE or mad cow disease -- was a foodborne disease. But his ... a 10-year-old cow from Alabama with an atypical form of bovine spongiform encephalopathy had the same type of prion protein gene mutation as found in human ...

Antibody key to treating variant CJD, scientists find

... It is thought that those who have developed vCJD became infected through the consumption of cattle products contaminated with Bovine Spongiform encephalopathy (BSE) a brain disorder in cows, commonly known as Mad Cow Disease. Prion diseases can develop when a naturally occurring brain prion protein ...

Genetic mutation causes familial susceptibility for degenerative brain disease

... in and out of the cell's genetic command center the nucleus puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). This is the conclusion of a global study to be published Jan. 9 by the American Journal of Human Genetics , and currently posted online, ...

Scripps scientists develop new tests that identify lethal prion strains quickly and accurately

... for proteinaceous infectious particles) are unique infectious pathogens associated with some 15 different diseases, including Bovine Spongiform encephalopathy (mad cow) and its rare human form, variant Creutzfeldt-Jacob disease. Infectious prions, which are thought to consist mainly of an abnormally ...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

... appeared in humans after several recent epidemics of bovine spongiform encephalopathy or "mad cow" disease. Since then, barriers to the transmission of prion ... ineffective. There have been hundreds of thousands of bovine spongiform encephalopathy cases, for example, and lots of people exposed to tainted beef products, ...

New treatment for severe malaria

... researchers at Karolinska Institutet in Sweden have developed a powerful new weapon against the disease. Severe anaemia, respiratory problems and encephalopathy are common and life-threatening consequences of serious malaria infection. The diseases are caused when the malaria bacteria P.falciparium infects ...

Prion find points way to test for human 'mad cow' disease

... The scientists say that they detected prions--the infectious proteins responsible for such brain-destroying disorders as bovine spongiform encephalopathy (BSE) in cattle and vCJD in humans--in the blood of the hamsters in as few as 20 days after the animals had been infected. That discovery occurred ...

Brittle prions are more infectious

... for their roles in such fatal brain-destroying human diseases as Creutzfeldt-Jakob disease and kuru, and in the animal diseases, bovine spongiform encephalopathy ("mad cow" disease) and scrapie. Yeast and mammalian prions are proteins that transmit their unique characteristics via interactions in which an ...

Successful cell engineering may lead to mad cow prevention, say researchers

... in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease. Researchers Mark Westhusin and Charles Long in Texas A&M's College of Veterinary Medicine & ...

New results validating Pall prion reduction filter disclosed at ISBT Congress

... as variant Creutzfeldt-Jakob Disease (vCJD), emerge. An update on the latest measures to protect the public from the human form of Bovine Spongiform encephalopathy (BSE), commonly called Mad Cow Disease, and minimize risk of transmission through blood transfusion was presented here at the International Society ...

First technology to remove prions that cause vCJD from blood launched

... from red cells, the most commonly transfused blood component. Variant CJD, a fatal neurodegenerative disease, is the human form of Bovine Spongiform encephalopathy (BSE), also known as Mad Cow Disease. The CE mark means the new prion reduction filter meets pan-European essential requirements for safety of ...