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Downstream in Biological News

Bacteria create aquatic superbugs in waste treatment plants

... to multiple antibiotics---up to 100 yards downstream from the discharge point into the Huron River. Xi ... tested. The bacteria in samples taken 100 yards downstream also were more likely to resist multiple drugs ... The next step, said Xi, is to see how far downstream the superbugs survive and try to understand the ...

NEWSLETTER: Antibody Fragment Production Breakthrough with 2nd Generation EBA

... Richter-Helm BioLogics has finalized the downstream process for Phase III clinical trial material ... microbial derived products, providing a superior downstream process for clinical manufacturing. Richter-Helm ... pressures and has been rewarded with a superior downstream offering in the CMO market. The Rhobust® ...

University of Michigan installs second Genomatix Genome Analyzer

... a complete, integrated analysis solution for the downstream analysis of NGS data, starting with mapped data ... add Genomatix advanced Next Generation Sequencing downstream analysis capabilities to our ongoing effort of ... The Genomatix Genome Analyzer (GGA) delivers downstream software tools and databases for the deep ...

Case Western Reserve finds mechanism underlying alt. splicing of premessenger RNA into messenger RNA

... sites, a weak site and a much stronger site downstream of it. Only one of them can be activated to make ... that beginning point to a common ending point downstream of both beginning splice points. The research ... nucleotides in a sequence of 12 nucleotides just downstream of the stronger splice site and in 12 just ...

Transporting juvenile salmon hinders adult migration

... fish populations. Juveniles that are transported downstream on boats can lose the ability to migrate back to ... survival of fish that hatch in rivers but migrate downstream to the ocean, where they live most of their adult ... spawning grounds, but some will instead move back downstream over dams," says Keefer. This phenomenon, called ...

Newly discovered molecular switch helps decide cell type in early embryo development

... Hox genes are responsible for regulating other downstream genes, to determine body position and help form ... during early development. Sens regulates downstream genes that support the development of sensory ... "This allows us to identify other key genes downstream of Hox and Sens, determine their role in ...

New research offers prioritization plan for reducing nutrient pollution in feeder streams

... projects, which is critical for decreasing the downstream movement of nitrogen. Unlike previous research ... and designing projects aimed at reducing the downstream flux of nitrogen, the researchers hope to help ... to local streams and are then transported downstream without being used by the local ecosystem. Small ...

More comprehensive analysis of Klamath River basin needed to aid decision makers

... fishes in the main stem of the Klamath River, downstream from Iron Gate Dam. The Natural Flow of the ... that the IFS recommendation for increased flows downstream from Iron Gate Dam probably would benefit the ... anadromous fish species in the Klamath River downstream from Iron Gate Dam. The most critical ...

Double trouble for water life

... that affect upstream waters have significant adverse consequences on downstream waters. Therefore, it is essential to look at nutrient control measures ... part of the larger scale eutrophication problem and at worst aggravate downstream ecological conditions." ...

EPA and USDA should create new initiative to better monitor nutrients

... across the river basin and identifying water-quality improvements downstream in the gulf." The Gulf of Mexico's oxygen-depleted "dead zone" derives ... a network of pollution-control pilot projects to evaluate local and downstream water-quality improvements, and to compare results and enhance the ...

Alpine rivers hold important clues for preserving biodiversity and coping with climate change

... not only because water, sediment and organisms move between upstream and downstream reaches, but also because the faster flowing and deeper middle of the ... process is applied at different sites along rivers to maintain upstream to downstream connections between affected sites if sustainable benefits to the river ...

'Himalaya -- Changing Landscapes' photo exhibition draws attention to the impacts of climate change

... have formed huge glacial lakes at the foot of the glacier, threatening downstream communities in case of an outburst", says Byers. The Himalaya Changing ... a mountain population of around 200 million, while the vast water basins downstream are home to a further 1.3 billion people. In total 1.5 billion people a ...

Evolving designer ecosystem sheds light on unintended consequences

... streams' capacity to remove nitrates and the resulting pollution of downstream rivers has been linked to the proliferation of coastal dead zones. "We ... flooding, recreation, and regulation of nutrient concentrations reaching downstream systems." ...

Hatchery fish outnumber wild chinook salmon in troubled fall run

... and artificially fed in the hatcheries, they also get a free ride downstream in tanker trucks. The hazards associated with migrating downstream to the ocean range from predators to the pumps that siphon water out of ...

Streams natural filters, if not overloaded

... for eutrophication the excessive growth of algae and aquatic plants in downstream lakes and coastal marine waters, said Jack Webster, professor of biology ... the most prevalent form of nitrogen pollution. They then measured how far downstream the nitrate traveled and how what processes removed it from the water. ...

Overexcited neurons not good for cell health

... if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells. Now a Northwestern University ... damaged proteins. When a neurons electrochemistry is imbalanced every cell downstream is imbalanced. Weve revealed that its an integrated communications network ...

Between water and rock -- a new science

... For instance, attempted cleanups can mobilize contamination release downstream or within a contamination plume through nanoparticle transport. And ... Despite remediation, elevated levels of metals occur more than 300 miles downstream from the mining source. Hochellas group has sampled the riverbed and ...

December GEOLOGY and GSA TODAY media highlights

... of salinity increases. These increases were typically located at the downstream end of sedimentary basins, where the regional groundwater flow system ... the Rio Grande, they are the dominant solute input and, when combined with downstream evaporation and transpiration, result in salinization. The recognition of ...

New molecular regulators of hyperthyroidism and goiter

... the body increases the amount of energy it burns) and goiter. Signals downstream of the receptor for TSH had been thought to be mediated mainly by a ... therefore suggest that inhibiting Gq and G11, or the molecules activated downstream of these G proteins, might be of therapeutic benefit for individuals with ...

JCI table of contents: Aug. 9, 2007

... the body increases the amount of energy it burns) and goiter. Signals downstream of the receptor for TSH had been thought to be mediated mainly by a ... therefore suggest that inhibiting Gq and G11, or the molecules activated downstream of these G proteins, might be of therapeutic benefit for individuals with ...

Abnormal brain circuits may prevent movement disorder

... cerebellar pathway problem in all DYT1 carriers. When we went back and looked at those without symptoms, we saw that they had an additional lesion downstream in the portion of the pathway connecting directly to the motor cortex." This second area of pathway disruption abrogated the effects of the first ...

Plankton Power and RTDC announce proposed algae-to-biofuels pilot facility on Cape Cod

... Massachusetts for a leadership role in the development of a critical new, renewable source of energy that will create local jobs in algae farming and downstream industries, advance energy independence, and reduce greenhouse gas emissions." The algae farm facility's location near MBL and WHOI will ...

DOE-funded research projects win 46 R&D 100 Awards for 2009

... from Flue Gas - Partially burned coal is extracted from a pulverized coal-fired combustor using a suction pipe, or "thief," and injected into the downstream flue gas to absorb mercury. (Jointly with Nalco-Mobotec, Orinda, CA) Virtual Engineering Process Simulator Interface (VE-PSI) jointly with Ames ...

Technology improves salmon passage at hydropower dams

... 3-D computational fluid dynamic model created by researchers at PNNL and the Corps' Portland District. The Corps is building a concrete guide wall downstream of the dam's spillbays. The researchers' computer model showed such a wall would help move fish away from shallow waters downstream. Predatory fish ...

Stanford researchers publish comprehensive model for medical device development

... and pharmaceuticals, and the corresponding differences in their development processes and regulatory requirements. Such variations have dramatic downstream effects that distinguish the capital requirements, product development methods, clinical testing requirements, manufacturing methods, and overall ...

Troubled waters: Low Apalachicola River flow may hurt gulf fisheries

... population of the Atlanta metropolitan area, and Florida and Alabama's contention that this flow reduction could have negative consequences for the downstream river environment. The Apalachicola River is considered a "hot spot" of ecological biodiversity, and Apalachicola Bay supports extensive finfish ...

The bitter side of sweeteners

... Sewage treatment plants fail to remove artificial sweeteners completely from waste water. What's more, these pollutants contaminate waters downstream and may still be present in our drinking water. Thanks to their new robust analytical method, which simultaneously extracts and analyses seven ...

Supply-Chain Council Announces Winners of 2009 Supply Chain Excellence Awards

... between subcontractor and manufacturer with clear mapping to SCOR mega processes in order to gain process and data visibility of upstream and downstream supply chain," said Dr. Tom Janoshalmi, Chair of the SCC Technical Development Steering Committee and Manager, Corporate Strategy, SAP & Business ...

UNH: Pavement sealcoat a source of toxins in stormwater runoff

... concentrations decreased after several rainstorms. The PAH concentrations in the sediments mirrored these trends; the concentrations immediately downstream of the coal tar-sealed lot increased by nearly two orders of magnitude within the first year. Unlike other compounds, PAHs do not break down ...

Stanford scientists find new solutions for the arsenic-poisoning crisis in Asia

... scientists pinpointed the source of the contamination in the Himalaya Mountains, where sediments containing naturally occurring arsenic were carried downstream to heavily populated river basins below. But one mystery remained: Instead of remaining chemically trapped in the river sediments, arsenic was ...

GEN reports biomanufacturers target a fully disposable process stream

... disposable bioprocessing market has moved far beyond plastic bags for buffer preparation toward a range of products for cell culture and upstream and downstream operations, reports Genetic Engineering & Biotechnology News (GEN). Increasing numbers of biomanufacturing experts now believe that a completely ...

CRG buys Genomatix' Next Generation Sequencing analysis solution

... and will contribute substantially to the analysis of data produced by their sequencers. " The Genomatix Genome Analyzer (GGA) delivers all downstream tools and databases for deep biological analysis of mapped data coming from next generation sequencers. It allows for easy integration and ...

Boehringer Ingelheim uses Genomatix' Next Generation Sequencing data analysis systems

... units. For genomic re-sequencing and newly sequenced genomes, a de novo assembly will be provided. The Genomatix Genome Analyzer (GGA) delivers downstream software tools and databases for the deep biological analysis of data coming from the GMS. It allows for easy integration and visualization in the ...

Calculating gene and protein connections in a Parkinson's disease model

... that the yeast had gotten sicker. However, when researchers added the molecule ubiquinone (also known as coenzyme Q10 or CoQ10), which is farther downstream in the statin network and possibly undersynthesized in alpha-synuclein-containing yeast, ubiquinone modestly suppressed alpha-synuclein toxicity. ...

Researchers call for nitrogen and phosphorus reductions to combat eutrophication in aquatic systems

... Center for Environmental Science. "Efforts focusing on only one nutrient can possibly help freshwater systems, but tend to push pollution problems downstream into coastal and estuarine systems." "Policymakers need to adopt holistic approaches when combating eutrophication," added lead author Dr. Daniel ...

Nutrient pollution chokes marine and freshwater ecosystems

... and ignoring nitrogen inputs, existing management strategies are exacerbating the decline of coastal ecosystems. We need to stop passing the problem downstream and adopt dual-nutrient reduction strategies." Eutrophication is a problem of global concern. Worldwide, there are over 415 eutrophic coastal ...

Cells with double vision

... receptive field is first compared with the information received by its neighbouring cells. Only then is the information relayed to cells further downstream in the network for the purpose of flight control. Getting to the bottom of it The immediate prediction from this work was somewhat of a ...

Engineers create intelligent molecules that seek-and-destroy diseased cells

... side effects. "This is all very front-end work," Smolke said. "We've just started to move these foundational technologies into these sorts of downstream medical applications, and so there is a lot to learn which makes it that much more exciting." Smolke's work is funded by the National Institutes ...

Ocean islands fuel productivity and carbon sequestration through natural iron fertilization

... biological productivity in large areas of the Southern Ocean is limited by the supply of iron, an important micronutrient for phytoplankton. However, downstream of ocean islands in this study area, massive phytoplankton blooms have been observed, leading to the idea that the islands themselves are somehow ...

Researchers identify new function of protein in cellular respiration

... energy generation and energy demands such as occurs in cancer and heart disease," he said. Next, the team will conduct studies to determine the downstream targets of Stat3 in the mitochondria and identify the physiological role of Stat3 that is localized to the mitochondria in heart disease and cancer. ...
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(Date:4/17/2014)... one per eight hundred births, Down syndrome - or ... of intellectual disability. It results from a chromosomal abnormality ... of chromosome 21 (1% of the human genome). A ... the Department of Genetic Medicine and Development at the ... Nature , shed light on how the extra ...
(Date:4/17/2014)... years ago, Katia Silvera , a postdoctoral scholar at ... a field trip in a mountainous area in central Panama ... before. , Unable to identify it, they contacted German Carnevali, ... to be an unnamed species. So Carnevali recently named it ... the genus name, comprising about 40 species in the world. ...
(Date:4/17/2014)... deforestation and fragmentation of forests in the Amazon ... forests, contributing to rapid and widespread forest loss ... researchers., The findings show that forests in the ... droughts coupled with forest fires lead to large-scale ... Jennifer Balch, assistant professor of geography, Penn State. ...
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(Date:4/20/2014)... A single type of cell in the lining ... invasive bladder cancer, according to researchers at the Stanford ... mice, is the first to pinpoint the normal cell ... It,s also the first to show that most bladder ... one cell, and explains why many human bladder cancers ...
(Date:4/18/2014)... published online in The Gerontologist ... is associated with a decrease in anxiety about death ... control over their lives. In particular, listening to gospel ... death and an increase in sense of control. , ... and men, and individuals of both low- and high-socioeconomic ...
(Date:4/18/2014)... one of your worst memories? How did it make ... during a negative personal experience, such as how sad ... to emotional distress, especially when you can,t stop thinking ... up, thinking about the context of the memories, rather ... effective way to alleviate the negative effects of these ...
(Date:4/18/2014)... 18, 2014) ― A new study in the ... in health-related Google searches reveals a recurring pattern that ... , Investigators from San Diego State University, the ... Campaigns, analyzed "healthy" Google searches (searches that included the ... originating in the U.S. from 2005 to 2012. They ...
(Date:4/17/2014)... The presence of chronic inflammation in benign prostate ... cancer, and this association was found even in ... to a study published in Cancer Epidemiology, ... American Association for Cancer Research. , An analysis ... of the placebo arm of the Prostate Cancer ...
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