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Differential in Biological News

From sheet metal elements to host cells: DFG launches 10 new collaborative research centers

... Research Centre 71, "Geometric Partial differential Equations", studies a whole series of ... physicists. These can either be based in differential geometry or involve applications requiring ... main objective is to study geometrical partial differential equations using analytical and numerical methods ...

Scientists find clue to mechanisms of gene signaling and regulation

... being methylated, or silenced. This kind of differential gene expression is called "imprinting." In the ... pairs between CGs provides a signal for where the differential methylation should take place," says senior ... eminent scholar. "So far only about 20 regions of differential methylation have been identified in the mouse ...

American Chemical Society Weekly PressPac -- April 8, 2009

... and noncapacitated sperm samples. They identified 44 peptides exhibiting differential phosphorylation, on 59 specific amino acids, suggesting that modification ... sperm "in the mood." - MTS ARTICLE #1 FOR IMMEDIATE RELEASE "Use of differential Isotopic Labeling and Mass Spectrometry To Analyze Capacitation-Associated ...

Racial disparities in cardiovascular health linked to birth weight, slavery

... of slavery and discrimination, with rural and inner city neglect, with differential wealth and differential access to health care, with cultural traditions and cultural biases, ...

Fate in fly sensory organ precursor cells could explain human immune disorder

... cells arise from a single sensory organ precursor mother cell. Among the daughter cells, Notch is activated in one and not in the other. This differential activation of signaling results in two different kinds of cells which arise from the same mother cell. Thus the fruit flies sensory organ precursor ...

Computer model predicts brain tumor growth and evolution

... cells consume and the rate of oxygen diffusion, and quantitative measures of cell growth and metabolic rates. The model is a series of interdependent differential equations. Each equation includes variables, or numerical values that can be experimentally manipulated. For example, to test if oxygen ...

Mothers give interloper's offspring a head start in life

... faster), or gets stored in a more advantageous position within the female's reproductive tract such as closer to the site of fertilization. "The differential success of sperm from different males is a fascinating possibility but remains untested in wild birds." While the study suggests that the superior ...

Lyncean Technologies Inc. receives $1.2 M from NCRR to develop new imaging technique

... used for Magnetic Resonance Imaging in medical clinics. The first scientific publication using the CLS x-ray beam employed a technique called differential Phase Contrast Imaging (DPCI) developed by Professor Franz Pfeiffer (now at TU Munich) and collaborators at the Paul Scherrer Institute in ...

Protein analysis methods, viral vectors featured in Cold Spring Harbor Protocols

... sodium dodecyl sulfate PAGE (SDS-PAGE), the procedure can resolve the complexes and their subunits by their molecular weight. In conjunction with differential in-gel electrophoresis (DIGE), BN-PAGE can be used to quantify changes in protein complex abundance or subunit composition between different samples. ...

GEN highlights increasing use of digital gene expression profiling

... continuously increasing number of reads at reduced costs, RNASeq, a.k.a. whole transcriptome shotgun sequencing, will become affordable for standard differential gene-expression analysis. DNAStar recently introduced QSeq, the first product to use the company's disk sort alignment algorithm for quantitative ...

Ali Shilatifard and colleagues aim to clarify the definition of 'epigenetics'

... about the distinction between the mechanisms of epigenetic memory during early development versus those of dynamic chromatin regulation involved in differential expression of genes throughout adult life. The mechanisms underlying epigenetic memory are of great importance to human development and disease, but ...

'Climate change: Global risks, challenges and decisions'

... and economic costs of both adaptation and mitigation. Key Message 4: Equity Dimensions Climate change is having, and will have, strongly differential effects on people within and between countries and regions, on this generation and future generations, and on human societies and the natural world. ...

Empire State Stem Cell Board awards $12.7 million to Albert Einstein College of Medicine

... of adipocyte progenitor cells during adipose tissue turnover and obesity. Carl Schildkraut, Ph.D., professor of cell biology $1,080,000 differential regulation of DNA replication during neural lineage specification in human embryonic stem cells and human induced pluripotent stem (iPS) cells. ...

New 'pollution radar' developed to provide unprecedented picture of urban smog

... a key role in meeting this challenge." During 2009 two new CompAQS instruments are being constructed and configured for use as a ground-based differential Optical Absorption Spectroscopy (DOAS) system by the University of Leicester, in collaboration with partners at Surrey Satellite Technology Ltd. ...

Is the Dead Sea dying?

... The receding water has left leveled sections on the lake's sides erosional terraces which the authors recorded precisely for the first time using differential Global Positioning System (DGPS) field surveys. They were able to date the terraces to specific years. The authors point out that this rapid drop ...

Long-term study of orchard ground cover management systems

... biomass, inorganic, and geotextile mulch. Although root systems play an important role in tree growth and development, little is known about differential GMS effects on orchard root growth and distribution. Researchers Shengrui Yao (University of Minnesota) and Ian A. Merwin and Michael G. Brown ...

Measuring molecules to improve drug design

... sizes of proteins which could help scientists create new pharmaceuticals that are a better match for the proteins they target. The method, called differential Aberration Correction (DAC) microscopy, measures distances at the molecular level in two and three dimensions using conventional fluorescence ...

January GEOLOGY media highlights

... by periods of relative quiescence. Tizzani et al. investigate the cause of unrest by a joint inversion of surface deformation measurements, based on differential synthetic aperture radar interferometry (InSAR), and microgravity data. The critical convergence of geodetic and microgravity data require a local ...

Genetic mutation causes familial susceptibility for degenerative brain disease

... to recommend that ANE linked to mutation of RANBP2 be designated as ANE1. They also recommended that ANE1 and mutation of RANBP2 be considered in the differential diagnoses of patients showing symptoms consistent with ANE. In a missense gene mutation, a single portion of the gene's DNA is reconfigured so ...

The medium is the message: Manipulating salmonella in spaceflight curtails infectiousness

... both spaceflights, bacteria cultured in a nutrient-rich medium known as Lennox Broth (LB) consistently displayed a heightened virulence and exhibited differential expression of 167 distinct genes. These results were largely consistent with previous earthbound experiments in the laboratory, in which ...

December Geosphere media highlights

... strongly diachronous, with north-south and east-west normal faulting that migrates in tandem from east to west, respectively, an expression of slab differential roll back along northern and southern parts of the Hellenic subduction zone. Extension in the Hellenic orogen was accompanied by late Cenozoic ...

Ants may help researchers unlock mysteries of human aging process

... the everyday activity of the colony and focused only on reproductive tasks, queens live up to 10 times longer than worker ants. As a consequence of differential aging and different behaviors, some regions of the queen's brain, such as the visual system, are not as well developed as those of the workers. Even ...

Scripps research team defines new painkilling chemical pathway

... receptors, namely hypothermia and decreased movement. "This really does suggest a sort of segregation of labor, if you will," says Cravatt of the differential effects of elevating AEA versus 2-AG as part of the overall function of the cannabinoid system. "That, I think, is a truly unique result." While ...

Fountain of Youth to be found in the anthill?

... of differences in ant behavior and development. They contacted my colleague Bert Hlldobler, who knew I was looking for geneticists interested in differential gene expression in behavior, aging, and development in ants." Hlldobler is the Pulitzer Prize winning coauthor of "The Ants," and leading expert in ...

Worker ants of the world, unite! You have nothing to lose but your fertility

... them as the "one special difficulty, which at first appeared to me insuperable, and actually fatal to my theory." If adaptive evolution unfolds by differential survival of individuals, how can individuals incapable of passing on their genes possibly evolve and persist? Darwin proposed that in the case ...

National and international doctoral training

... University of Jena. In close collaboration between physicists and mathematicians the Group is making use of the interface between field theory and differential geometry. The aim is therefore to exploit the innovative cross-fertilisation of physics and mathematics to search for completely new dis-coveries in ...

New gene-silencing pathway found in plants

... at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes. differential gene expression profoundly influences the way in which organisms grow and develop. For instance, although every cell in the human body has the same ...

Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida

... examples of mathematical modal analysis of musical instruments using a finite element computer program, which sidestep solving the complicated differential equations governing the modes through the use of numerical methods. The session "Musical Acoustics and Structural Acoustics and Vibration: ...

NIST trumps the clumps: Making biologic drugs safer

... drugs during the manufacturing phase. To address the problem, NIST researchers hit upon the idea of adapting a technique known as electrospray differential mobility analysis (ES-DMA). Commonly used to size soot and other aerosols, ES-DMA uses an electric current to vaporize a solution of proteins into ...

UC San Diego researchers could help US military thwart explosive threats

... object." Current explosive detection technology used by the U.S. government includes X-Ray machines; machine olfacation (gas chromatography and differential mobility spectrometry); neutron activation, in which the machines bombard the suspect explosives with neutrons and read the gamma radiation decay ...

Can you be born a couch potato?

... to show a genetic effect that could cause a difference in muscle performance. "We have done some gene chips on muscle tissue and we don't see any differential expression between high-active and low-active animals in peripheral (muscle) tissue," Lightfoot said. "So the suggestion that by over-expressing a ...

HapMap browsing and DDDP methods for genetic analysis featured in CSH Protocols

... ). The second featured method for July, "In Vitro Screening for Regulated Transcription Factors with differential Display of DNA-Binding Proteins (DDDP)," provides a method for identifying proteins that are actively binding DNA and playing a role in gene ...

Estimation of isolation times in the Drosophila simulans complex

... is similar for both classes. This might reflect gene flow of the low-recombination loci subsequent to initial isolation, but it might also reflect differential effects of changing population size on the two recombination classes of loci when the low-recombination loci are subject to genetic hitchhiking or ...

Pitt receives $2.5 million to simulate and analyze brain, immune system activity

... of Arts and Scienceswhich houses the mathematics departmentprovided additional funds. The team will create a variety of computer models based on differential equationswhich predict how systems evolve over timewith the medical guidance of scientists and doctors in Pitt's Departments of Biological Sciences ...

Chocolate bar shown to lower cholesterol

... Evans, a U. of I. professor of kinesiology and community health and co-author of the study. After starting the CocoaVia bars, we saw a marked differential effect on blood cholesterol, with the sterol-containing products doing better than those without sterols, she said. A CocoaVia bar contains 100 ...

Need for federal protection against genetic discrimination

... or establish eligibility, enrollment, or premium contribution requirements. Position 2: Insurance providers should be prohibited from establishing differential premiums based on an individuals genetic information or request for genetic screening. ACPs policy positions result from a March 2007 survey ...

Are existing large-scale simulations of water dynamics wrong?

... heterogeneity of soils and the sometimes complicated topography. Simulation models are typically based on Richards' equation, a nonlinear partial differential equation, which can be solved using numerical solution methods. A prerequisite of most solution algorithms is the partitioning of the simulated ...

MIT applies engineering approach to studying biological pathways

... then compared those inputs with the resulting Hog1 activity. Using that data and standard methods from systems engineering, they came up with two differential equations that describe the three major feedback loops in the pathway: one that takes action almost immediately and is independent of the kinase ...

Media highlights in the January issues of Biophysical Journal

... complexes. The ability of the DNA sequence itself to contribute significantly to nucleosome stability and DNA accessibility provides a mechanism for differential recognition of specific nucleosomes, such as those on key promoter elements. Significant sequence-dependence nucleosome stability is not ...

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity

... new study published in the January 1st issue of Biological Psychiatry provides some interesting data to aid in that goal. The authors report that differential effectiveness of antipsychotic treatment was predicted, in a subset of patients with schizophrenia, by variants of the gene encoding for the ...
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