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Clearance in Biological News

Study: Fluid buildup in lungs is part of the damage done by the flu

... Detailing exactly how flu interferes with fluid clearance in the lungs lays the groundwork for a second ... A virus to compare oxygen levels and fluid clearance in infected mice to those of healthy mice. ... in the lungs. Two days after infection, fluid clearance in these mice was only half as effective as ...

Why some primates, but not humans, can live with immunodeficiency viruses and not progress to AIDS

... and in initiating immune responses that enable clearance of these infections. They detect the invaders ... Unfortunately, rather than promoting clearance of the infection, chronic dendritic cell ... response to a virus that is so resistant to clearance by antiviral immune responses. The authors ...

In scientific first, Einstein researchers correct decline in organ function associated with old age

... suggest that therapies for boosting protein clearance might help stave off some of the declines in ... old mice. Does maintaining efficient protein clearance in liver cells of an older animal translate into ... to see whether maintaining efficient protein clearance in the brain might help in treating them. "Most ...

Clearance of hepatitis C viral infection after liver transplantation

... LC, since previous data indicated that complete clearance of HCV is the prerequisite for patients to have a ... HCV RNA was still detectable. Since the complete clearance of HCV RNA seemed impossible, the liver ... was performed. Unexpectedly and excitingly, clearance of HCV RNA was achieved just one month after the ...

Logging road threatens rare peat dome, tigers

... stores. The road would allow APP and affiliated companies to restart clearance of natural forest and destruction of deep peat soil at any time in a ... Forestry has issued definitive licenses to the two concessions. However, clearance of natural forest for plantation development in these concessions would ...

Aging gracefully requires taking out the trash

... once created at birth. They rely on autophagy together with other clearance and detoxification pathways to keep themselves healthy and functioning for ... says Simonsen, but most importantly they demonstrate that enhancing the clearance of damaged proteins and protein aggregates increases longevity. Insulin ...

LSUHSC's Kolls awarded $1.8 million to improve vaccine strategies for P. carinii pneumonia

... antibodies are part of the natural response to the Pneumocystis fungus. Theses preliminary studies show that these antibodies participate in early clearance of the organism from the lung as well as regulate long term immune responses to the organism. The research team believes that this response might be ...

Mothers pass on disease clues to offspring

... see if the ambient exposure affected their immunity. The offspring which had developed in the diseased environment showed an earlier onset, peak and clearance of the infection than the offspring from the control dams. The research group in the University's School of Biology have studied many populations ...

Medicare coding for maggots and maggot therapy

... therapy is the use of specially prepared fly larvae for treating chronic wounds. Medical Maggots brand of medicinal maggots were granted marketing clearance by the FDA in 2004 for treating neuropathic (i.e., diabetic) foot ulcers, pressure ulcers ("bed sores"), venous stasis ulcers, and traumatic and ...

Even plants benefit from outsourcing

... or low quality seed." "This can lead to germination failure and poor seedling growth." Land and water degradation resulting from vegetation clearance is a global problem. Effective restoration techniques are essential in reducing the damage and improving the environment. In an effort to help, ...

Research conference at UH to focus on US troops' needs, homeland security

... will showcase defense-oriented research projects under way at UH. Defense Department speakers will cover cyber-command research needs, security clearance restrictions, post-traumatic stress disorder, homeland security, nanotechnology, human performance, advanced materials, and Navy and Air Force ...

Moderate quantities of dirt make more rain

... origin. The natural processes include volcanic eruptions, the occasional forest fire, sandstorms, and breaking ocean waves, while traffic, forest clearance by fire, changes in land use and industrial emissions are the major human sources. Not all aerosol particles can act as condensation nuclei; among ...

Pre-eclampsia may be autoimmune disease

... the leading causes of prematurity and Small For Gestational Age (SGA) infants. Many of these babies are born with underdeveloped lungs or poor lung clearance of fluid, necessitating neonatal intensive care admission and various respiratory therapies to support their breathing. We continue to struggle to ...

From foe to friend: Researchers use salmonella as a way to administer vaccines in the body

... strain from spreading into the environment. "The data show that the system we have devised results in cell lysis in the absence of arabinose and clearance of the strain from host tissues," the researchers state in the PNAS article. "More importantly, our strain was fully capable of delivering a test ...

World-class environment vision to 'bring back the species'

... "Ten species are already extinct in the Mt Lofty Ranges and a further 60 species continue to decline in numbers despite the cessation of vegetation clearance in the 1980s. Climate change will exacerbate these losses," he says. "This will be a terrible loss for all South Australians, but it is ...

Mechanism explains link between apolipoprotein E and Alzheimer's disease

... at Case Western Reserve University School of Medicine in Cleveland, Ohio. Dr. Landreth and colleagues sought to unravel the link between ApoE, A? clearance in the brain, and an enhanced risk for AD. The researchers found that ApoE profoundly enhanced the intracellular and extracellular degradation of A?. ...

Researchers find way to make tumor cells easier to destroy

... GRN163L, more strongly inhibited telomerase than the others. Many groups are studying GRN163L as an anticancer therapeutic, and it recently received clearance by the U.S. Food and Drug Administration to enter human phase I/II clinical testing in chronic lymphocytic leukemia. In some preliminary studies, ...

Nixing immaturity in red blood cells

... The difference generates a force that drives the synthesis of ATP, the cells energy molecule). We think the finding is not limited to the clearance of mitochondria in red blood cells, said Wang. When other cells get old or stressed, their organelles may become damaged and need to be cleared by ...

Destruction of Sumatra forests driving global climate change and species extinction

... safeguard endangered tigers, elephants and local communities. Carbon emissions are likely to increase, the study predicted, as most future forest clearance is planned for areas with deep peat soils. The loss of Sumatra's carbon-rich forest ecosystems is not just Indonesia's problem this affects the ...

Mayo Clinic study: Ossur's collars superior in immobilization and reduction of pressure

... injury necessitates the initiation of spinal precautions in all such patients before cervical spine clearance. Failure to achieve early spinal clearance predisposes the patient to increased morbidity secondary to extended immobilization. Trauma represents 11.4% of non-pediatric and non-maternity ...

UN climate conference hears how EO can help

... 25 billion tonnes of extra carbon dioxide is released into the atmosphere annually by human activities, mainly through burning of fossil fuels, land clearance and wildfires. Because deforestation in tropical rainforests accounts for as much as 20 percent of global greenhouse gas emissions, finding ways to ...

Cholesterol metabolism links early- and late-onset Alzheimer's disease

... of the cholesterol pathway," Bu says. "Right now, research on Alzheimer's treatment focuses largely on reducing A-beta production or increasing its clearance from the brain. Our study suggests that there could be an alternate way to treat the disease, perhaps by modulating the function of apolipoprotein E ...

October Geology and GSA Today media highlights

... Classic periods as Maya population densities rose exponentially. Anselmetti et al. infer that a pulse of intense erosion accompanied initial land clearance in the Pre-Classic period when highly erodable soils were first exposed. These results suggest that the Maya had to contend with soil erosion long ...

Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs

... is based on an analogue of poly(ethylene oxide), a well-established biocompatible polymer that can enhance blood circulation time and prevent clearance by the reticuloendothelial system, the part of the immune system that engulfs and removes foreign objects from the body, said Siegwart. In a ...

Production of key Alzheimer's protein monitored for first time in humans

... and sensitive way to monitor the production and clearance rates of amyloid beta peptide (Abeta) in the ... researchers had assumed that the creation and clearance rates for Abeta were very slow. But the initial ... nervous system." Ideally, the production and clearance rates stay balanced, causing the overall amount ...

Blocking immune cell action increases Alzheimer's-associated protein deposits

... plays a protective role in early Alzheimer's disease by mediating the clearance of amyloid-beta," says Joseph El Khoury, MD, of the MGH Center for ... down amyloid-beta deposits revealed that a lack of CCR2 appears to reduce clearance of the toxic protein from the brain. Other tests suggest that CCR2 is ...

Lack of a key enzyme dramatically increases resistance to sepsis

... units per milliliter of blood, suggesting that more efficient bacterial clearance occurs in the absence of caspase-12. Caspase-12 is also an inhibitor ... weaken the activity of caspase-1 that is normally essential for bacterial clearance and sepsis survival." In another finding, researchers showed that ...

The quest for an effective HIV vaccine presents new possibilities, challenges

... scientists?efforts thus far to develop a classic preventive vaccine for the virus because of its ability to integrate into target cells and evade clearance by the immune system. The interaction between HIV and the immune system is complex, and how different HIV-specific immune responses help to control ...

Funding to tackle hospital superbugs

... team led by Professor Topley and Dr Simon Jones has already identified new pathways that enhance the bodies natural defence mechanisms to promote the clearance of infection. The new approach has been named "Resolution Therapeutics" by the Cardiff researchers. It is hoped that research in the School of ...

Scientists find a key to immune system's ability to remember

... them to sense and react more quickly when an infectious agent is reencountered. "Now we know one of the reasons we get such a quick response and clearance (of the pathogen) with reinfection," Suresh explains. "If you increase the size of your army, you can clear your enemies faster. The memory T cells ...

Butterfly farming to help save rain forest

... Firstly the local population will have a sustainable business that allows them to turn away from other activities that would involve yet more forest clearance and secondly that butterfly farming actually needs to conserve the rainforest because that is the butterflies' preferred habitat. The research ...

Predicting successful outcomes in living-donor liver transplants

... authors conclude. In an accompanying editorial, Jürg Reichen, M.D., of the University Hospital, University of Berne in Switzerland notes that ICG clearance as measured in the first study can predict poor outcomes and might be useful for LDLT recipients, while the second study points out that liver ...

FDA approves first medical device using rutgers biomaterial

... Rutgers scientists and TyRx Pharma, Inc., have announced the Food and Drug Administration's clearance of a new medical device for hernia repair that incorporates a biodegradable technology developed at the university. This action signals a paradigm ...

Flesh-eating bacteria escape body's safety net

... with standard antibiotics, a treatment strategy to inhibit the Strep DNA-degrading enzyme could disarm the pathogen, making it susceptible to clearance by our normal immune defenses," he said. ...

The bioweapon is in the post

... by the US government as "select agents" that raise bioterror concerns. But not all of these sequences are dangerous, and some customers may have the clearance to work with those that are. So even legitimate orders may be flagged up as suspicious, and that means companies must employ biologists to carefully ...

Cyberkinetics, Case to develop system to help restore extremity function

... such as Brown University, the Massachusetts Institute of Technology, Emory University, and the University of Utah. Cyberkinetics has received FDA clearance to market the NeuroPort TM System, a neural monitor designed for acute inpatient applications and labeled for temporary (less than 30 days) ...

Muscle repair: Making a good system better, faster; implications for aging, disease

... substances. PAI-1 deficient muscles showed "increased macrophage accumulation (and) the extent of macrophage accumulation correlated with both the clearance of (damaged) protein after injury and the efficiency of regeneration," according to the report. Macrophage accumulation was impaired in injured ...

Pinpointing the cause of a neurodegenerative disorder

... patients can no longer eat or breathe. "We had known that the expansion of the glutamine tract within Ataxin-1 probably interfered with normal clearance of Ataxin-1, meaning that it accumulated in cells," said Zoghbi. She noted that earlier studies yielded hints that the glutamine repeats somehow ...

Affymetrix and bioMerieux Extend Their Agreement on GeneChip(R) Technology to Breast Cancer Diagnostics

... that are developed, branded and marketed by diagnostic companies. This includes the GeneChip System 3000Dx, which has been granted regulatory clearance by the U.S. Food and Drug Administration and CE marked in the European Union for in-vitro diagnostic use. "bioMerieux provides a full range of ...
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(Date:4/17/2014)... one per eight hundred births, Down syndrome - or ... of intellectual disability. It results from a chromosomal abnormality ... of chromosome 21 (1% of the human genome). A ... the Department of Genetic Medicine and Development at the ... Nature , shed light on how the extra ...
(Date:4/17/2014)... Stem cells in bone marrow need to produce hydrogen ... tissue, according to a new study from the Center ... of Dentistry of USC. , Professor Songtao Shi, principal ... sulfide produced by the cells governs the flow of ... cellular signals that results in osteogenesis, or the creation ...
(Date:4/17/2014)... This news release is available in German . ... fails to pay the protection money demanded of him, he ... are seldom required, however, as fear of the consequences is ... is observed in parasitic birds, which lay their eggs in ... egg out, the brood parasites take their revenge by destroying ...
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(Date:4/18/2014)... researchers have been awarded two-year grants for their work ... month. Of the 110 initial submissions to the new ... only four projects were funded, three of which are ... M.D., Ph.D.; G. William Wong, Ph.D.; and Elias Zambidis, ... oncology, will use his $500,000 proof of principle grant ...
(Date:4/18/2014)... WA April 18, 2014) Benaroya Research Institute ... research how blocking a particular molecule in metastatic breast ... the number of lung metastases. BRI scientists have found ... can shrink tumors by 60 - 80 percent and ... the lung. The $1.8 million five-year grant comes from ...
(Date:4/18/2014)... 18, 2014) ― A new study in the ... in health-related Google searches reveals a recurring pattern that ... , Investigators from San Diego State University, the ... Campaigns, analyzed "healthy" Google searches (searches that included the ... originating in the U.S. from 2005 to 2012. They ...
(Date:4/18/2014)... Northwestern Medicine scientists could lead to potential new treatments ... with scleroderma. , Fibrosis, or scarring, is a ... skin and lungs can lead to serious organ damage ... new therapeutic options centers on findings made by Swati ... the role that a specific protein plays in promoting ...
(Date:4/17/2014)... show signs of chronic inflammation in non-cancerous prostate tissue ... prostate cancer than those with no inflammation, according to ... the Johns Hopkins Kimmel Cancer Center. , The link ... men with so-called high-grade prostate cancer those with ... the presence of the most aggressive and rapidly growing ...
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