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Channel in Biological News

Enzyme doesn't act alone in atrial fibrillation

... An overactive enzyme is behind a leaky calcium channel that plays a role in the development of atrial ... rates were raised, the mice with the calcium channel mutation had no signs of arrhythmia. Again the ... in the genetic code and stop the specific calcium channel from being affected by the enzyme. Further ...

Drug prevents seizure progression in model of epilepsy

... is associated with seizure disorders, a potassium channel known as the BK channel. "We have found a new ... could lead to the same alterations in BK channel function. Potassium ions move through the ... researchers found that after a first seizure, BK channel function was markedly enhanced. As a result, the ...

Uncooperative voltage sensors

... conformation at a depolarized voltage before the channel can open. Part of the evidence for this assertion ... gate from opening (Horn et al., 2000). Therefore, channel opening requires the participation of all four ... that if three of the voltage sensors in a channel are in a permanently activated conformation, the ...

Researchers discover that gene switches on during development of epilepsy

... to the condition. The gene codes a calcium channel in the brain that underlies seizures, so the ... the brain. If, as in epilepsy, a particular channel shows up where it is not supposed to or appears in too many or too few numbers, the function that channel is responsible for can become abnormal. ...

Journal of General Physiology explores mysteries of TRP channels in latest Perspectives series

... a critical overview of current research about TRP channel structure, and to point out areas in need of ... provides an historical context for the TRP channel story, which dates back to the 1960s and now ... of the functional properties of the TRPA1 channel and, in particular, that regarding its ...

Rare disease provides clues about enzyme role in arrhythmias

... Timothy syndrome, a mutation causes the calcium channel to be malformed. The heart muscle then takes ... II is a 'missing link' that connects this calcium channel mutation to arrhythmia and possibly other ... drive heartbeats. "By studying this mutant channel in an adult rat heart cell that had all the ...

'Deranged calcium signaling' contributes to neurological disorder, UT Southwestern researchers find

... ataxin-3 activates a molecule that acts as a channel in the membrane of a sequestered chamber inside cells called the endoplasmic reticulum, or ER. The channel then releases calcium into the cell as a whole. Normal ataxin-3 did not activate the channel or cause calcium release. The researchers ...

CIC Teams With Industry Leader iPipeline to Provide Electronic Signature Platform to the Nation's Top Insurance Carriers

... needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing ... to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in ... markets as an on-demand service. iPipeline's channel solutions for carriers, distributors, and agents ...

Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue

... on the nicotinic acetylcholine receptor, an ion channel found in both brain and muscle cells. The ... the outside of brain and muscle cells causing the channel to open and allow ions to cross the membrane. ... under." The receptor is a cation-selective channel central to both neuronal and muscular processes ...

Site used by sodium to control sensitivity of certain potassium ion channels

... understanding of the mechanisms involved in ion channel gating and may one day set the stage for new ... and a group of potassium channels known as Kir channel proteins. The team had previously shown that Kir3 ... by specific amino acids found in several Kir channel proteins. "We have a fairly good molecular ...

Evolving designer ecosystem sheds light on unintended consequences

... of stream flow. "Prior to these alterations, channel systems like those of Indian Bend Wash were ... connection to the groundwater (via loss from the channel bed)," notes Ramon Arrowsmith, professor with ... is short circuited with water entering the channel from well and canal sources, and water leaving by ...

MicroRNA implicated as molecular factor in alcohol tolerance

... a brain cell membrane structure known as the BK channel develops tolerance to alcohol, particularly in ... as decreased alcohol sensitivity and reduced BK channel density. Previous studies have also shown that there are numerous variants of the BK channel gene. In the current study, researchers led by ...

AGU journal highlights -- July 23, 2008

... outcrops in and around the Martian outflow channel Mawrth Vallis. Wray et al. additionally identify ... of layers occurs on both sides of the outflow channel and on its floor, with aluminum-rich clay-bearing ... clay-bearing layers are younger than the outflow channel and may represent a later sedimentary or altered ...

Researchers catch ion channels in their opening act

... controversy centers on a key segment of the ion channel called the voltage sensor. The voltage sensor ... the voltage across the membrane and instructs the channel to open or close. One model for the movement ... a small amount, tugging on the pore of the ion channel and opening it just enough for ions to get ...

Too hot to handle! Scientists identify heat sensing regulator

... heat and spice is controlled by the TRPV1 protein channel found on the surface of certain nerve cells. In ... the brain. The interesting thing about this channel is its not always constant, says Dong, whose team ... To figure out whether Pirt directly affects TRPV1 channel action, the researchers measured electrical ...

Insects evolved radically different strategy to smell

... They then measured how long it took for the ion channel to open and recorded their electrical movement as ... The ion channels don't resemble any known ion channel on Earth, says Vosshall. They are composed of two ... Touhara and Vosshall developed their ion channel hypothesis in parallel with Vosshall's work on ...

Researchers 'see' structure of open nicotinic acetylcholine ion channels

... membrane. Although normally closed, when the ion channel encounters acetylcholine or nicotine on the ... had been able to infer the structure of the open channel conformation in a living cell. The Illinois team ... can be engineered into the inner lining of the channel pore. These changes to the amino acid sequence ...

Chloroform provides clue to 150 year old medical puzzle

... chloroform inhibited, or blocked, the calcium ion channel TRPC5 it was quite a striking effect. Ion ... in the brain. We know that this ion channel plays a signalling role in the central nervous ... wondering whether inhibiting this calcium ion channel was one mechanism by which anaesthesia works, ...

Breakthrough in plant research

... is an intensively-studied topic and several ion channel types that control their activity have been ... the University of Helsinki identified the anion channel using a mutation of Arabidopsis thaliana commonly ... that the gene identified encodes an anion channel involved in the regulation of stomatal ....

AGU journal highlights -- Feb. 26, 2008

... passive microwave sensors, including the 89-GHz channel of the Earth Observing Systems Advanced Microwave ... drifts reveal that the data retrieved from this channel are fairly accurate. Using this channel, Kwok ... Title: Summer sea ice motion from the 18 GHz channel of AMSR-E and the exchange of sea ice between the ...

Fishermen and UCSB scientists explore ways to improve management of California spiny lobsters

... the first five years of marine reserves in the channel Islands area. An innovative collaboration has ... to establish no-take fishing reserves at the channel Islands. Research conducted by CALobster will ... Entitled The First Five Years of Monitoring the channel Islands Marine Protected Area Network, the ...

High blood pressure in older adults traced to gene's effects in blood vessels

... in thickness, decreasing the diameter of the channel through which blood normally flows. The gene, ... to increase in size. This in turn narrows the channel through which blood flows, causing stress on ... regulating blood flow, and the lumen, the open channel through which blood travels. In healthy young ...

Biophysical Society announces 2008 International Travel Awards

... Function of Bacterial Mechanosensitive channel MscS. Khundrakpam Budhachandra, Singh ... Addition of a Charge to the Shaker Potassium channel Voltage Sensor. Manuel Gutierrez-Aguilar, ... For A Conducting State Of MscS Mechanosensitive channel Using K+ Uptake-deficient Escherichia coli. ...

Micro microwave does pinpoint cooking for miniaturized labs

... be successfully integrated with a microfluidic channel to control selectively and precisely the ... heat the fluid in a selected portion of the micro channel while leaving the surrounding area unaffected. ... effect on the fluid temperature in the micro channel validated the model by showing that the increase ...

University of Pittsburgh cardiologists identify new cardiac arrest gene

... this study we found that GPD1-L, while not an ion channel itself, is a trafficking gene that allows the sodium channel to find its way to the cell membrane. The ... and maintain a stable rhythm. To date, only ion channel genes had been shown to cause Brugada syndrome. ...

New field-deployable biosensor detects avian influenza virus in minutes instead of days

... through a grating and travels under one sensing channel and one reference channel. Researchers coat the sensing channel with the specific antibodies and coat the reference channel with non-specific antibodies. Having the ...

Neural stem cell study reveals mechanism that may play role in cancer

... whether the molecule functioned as a channel to regulate cell proliferation within embryonic ... three plausible mechanisms: the well-known channel function, a form of cellular signaling that ... neurons. While roles for the gap junction channel in cancer have been demonstrated, Its possible, ...

September Geology and GSA Today media highlights

... Late Holocene strike-slip offset of a subsurface channel interpreted from three-dimensional seismic data, ... fault has right laterally offset a buried fluvial channel by a distance of 322506 meters. The channel is inferred to have formed when sea level was ...

International collaboration by scientists culminates in novel ion channels database

... for 8 VGIC and 3 LGIC families. Curation of the remaining five ion channel gene families is underway. The ion channel database is now available at: ...

New method separates cancer cells from normal cells

... ratcheting, is a very tiny system of channels for cell locomotion. Each channel is less than a tenth of a millimeter wide. The asymmetric obstacles inside ... and thin with long protrusions on the ends. The researchers designed a channel with "spikes" coming out at 45-degree angles from the walls, alternating ...

Striata and CIC Launch Integrated eSignature, eDelivery, and eBilling for the Financial Services Industry

... CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of ... paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and ...

New research helps explain how connexin hemichannels are kept closed

... regarding how they open in certain conditions as part of a junctional channel (1). As Harris explains, the gating mechanism that controls the ... the concurrent unveiling of a high-resolution structure of a connexin channel has been a long-awaited and noteworthy development (4). According to ...

Yale team identifies key to potential new treatment for allergy-induced asthma

... in asthmatic inflammation. The new study tracks the role of the ion channel protein TRPA1. While the exact function of TRPA1 in the airway ... understood, scientists do know from previous research that this ion channel protein is a sensor for chemical irritants such as cigarette smoke and ...

Using high-precision laser tweezers to juggle cells

... where a set of laser tweezers move the cell around in a microscopic channel system, allows the researchers to study how single cells react to stress ... Placing the cell in a system of channels made of silicone, in which each channel is finer than a human hair, enables the researchers to add and remove ...

Striata and CIC Launch Integrated eSignature, eDelivery, and eBilling for the Financial Services Industry

... CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of ... paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and ...

Flow of potassium into cells implicated in schizophrenia

... Expression of a previously unknown form of a key such potassium channel was found to be 2.5 fold higher than normal in the brain memory hub of ... healthy people who carry the risk-associated version of this potassium channel gene, even though they don't show any psychotic behavior." Evidence ...

Communication Intelligence Corporation Reports Fourth Quarter and Fiscal 2008 Results

... CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of ... paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and ...

Is the Dead Sea dying?

... time to consider the long-term alternatives such as the Red Sea-Dead Sea channel or the Mediterranean-Dead Sea Channel. The authors conclude that ... for energy production and desalinization to fresh water. Such a channel will also maintain tour-ism and potash industry on both sides of the Dead ...

CIC to Host Webinar Featuring Independent Research Firm: 'Enabling Straight Through Processing - Why the Insurance Industry Needs Electronic Signature Technology'

... CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of ... paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and ...

CIC Named to Independent Research Firm's 'Hot Banking Tech Companies to Watch in 2009' Report

... CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of ... paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and ...
Other Contents
(Date:8/20/2014)... George E. Fox, a John and Rebecca Moores Professor ... was named a fellow in the International Society for the ... is one of four members two from the U.S., ... fellows in 2014. Fellows are elected every three years, and ... members from more than 20 countries, the ISSOL includes researchers ...
(Date:8/20/2014)... ITHACA, N.Y. In a study of 158 pregnant ... the craving and intentional consumption of ice, cornstarch, ... items, reports a new Cornell study. , Moreover, such ... teens who did not eat nonfood substances. , Pregnant ... low hemoglobin, which can lead to iron deficiency and ...
(Date:8/20/2014)... Cancer Institute (HCI) at the University of Utah have ... encodes BCR-ABL, the unregulated enzyme driving the blood cancer ... Society, nearly 6,000 new cases of CML will be ... tyrosine kinase inhibitors (TKIs), target BCR-ABL and are effective ... but control it in a way that allows patients ...
Breaking Biology News(10 mins):UH professor named fellow by International Astrobiology Society 2Pica in pregnant teens linked to low iron 2Blueprint for next generation of chronic myeloid leukemia treatment 2
(Date:8/21/2014)... The "North American Interventional ... by Angioplasty Balloon (Plain/Old, Cutting), Stent ... Filter (Retrievable), Endovascular Stent Graft - ... the major market drivers, restraints, and ... , Browse 108 market data tables ...
(Date:8/21/2014)... Rebecca Tabbert, owner of Calimesa Fit Body ... enjoyed watching as more people turn away from the ... camp environment. It’s not only good for her business; ... ‘treadmill-dumbbells-elliptical’ routine just doesn’t work,” she says. “Numerous research ... and lifting those cute little dumbbells does very little ...
(Date:8/21/2014)... Bedros Keuilian’s Annual Fitness Business Summit is considered ... many people already earning seven-figure incomes. But his annual ... open to the owners of Keuilian’s own international fitness boot ... Body Boot Camp World Conference will also be attended by ... camp or are struggling with their own boot camp ...
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(Date:8/21/2014)... August 21, 2014 mynt welcomes industry ... promoters to join its growing company. Since its pre-launch ... in product sales and continues to gain momentum leading ... , Rob and Tiffanie came into network marketing by ... a number of network marketing companies. Tiffanie needed help ...
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