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Cells in Biological News

NIH stimulus funding supports Emory biomedical scientists

... treatments for humans. The role of memory T cells in transplant rejection: Memory T cells allow the immune system to respond to infections ... body to fight bacteria and stimulate the muscle cells that line blood vessels. This project looks at ...

New cancer drug delivery system is effective and reversible

... developers, finding an agent that kills tumor cells is only part of the equation. The drug must also ... antibody-conjugated liposomes to bind to cancer cells can be inconsistent. Some small molecules, ... cisplatin, a drug that effectively kills cancer cells but has troublesome side effects when ...

Growing evidence of marijuana smoke's potential dangers

... smoke vs. tobacco smoke in terms of toxicity to cells and to DNA. Scientists exposed cultured animal cells and bacteria to condensed smoke samples from both ... smoke caused significantly more damage to cells and DNA than tobacco smoke, the researchers note. ...

Pitt researchers find promising candidate protein for cancer prevention vaccines

... when inflammatory responses are strong. cells infected with chicken pox virus, for example, look very much like tumor cells because they, too, overproduce cyclin B1. The ... to the immune system as a marker of infected cells that must be destroyed. "Because cyclin B1 is ...

New stem cell research could reduce number of animal experiments

... will be developing a technique using human stem cells to study this debilitating neurological disease, ... the number of animals used in research. Stem cells are the precursor cells that are able to develop into more ...

La Jolla Institute discovers novel tumor suppressor

... characterized by an overproduction of blood cells by the bone marrow and include chronic myeloid ... Myeloproliferative diseases develop when myeloid cells -- which make certain types of white blood ... become overactive and produce too many blood cells leading to myeloproliferative disease, he ...

Protecting cells from their neighbors

... determined. It is dictated by the separation of cells that will become sperm and ovules - germ cells-, ... identified the mechanism that protects somatic cells against the behaviour of germ cells. When this ... In the first hours of embryonic life, the egg cells show intense gene transcription activity to ...

Stem cell 'daughters' lead to breast cancer

... scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers ... have discovered that luminal progenitor cells the 'daughters' of breast ...

Parasites ready to jump

... We now want to find out whether mammalian cells possess this newly discovered defence mechanism ... in the fertility of the progeny. Germ cells are an ideal target for transposons, since these cells pass their genetic material together with ...

Got zinc? New zinc research suggests novel therapeutic targets

... immune function, but increases activation of the cells (T cells) responsible for destroying viruses and ... zinc on T cell activation. After isolating the T cells from the blood, scientists then simulated ... in laboratory conditions. Results showed that T cells taken from the zinc-supplemented group had higher ...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and ... cancer that has promise for targeting tumor cells and leaving healthy cells healthy," said lead researcher Janet Sawicki, ...

A crystal ball for brain cancer?

... creates an independent blood supply. Cancer cells secrete a growth factor called VEGF that spurs ... events that is detectable by MRI. Oxygen-starved cells produce more VEGF, which causes blood vessels to ... to move freely in the tumor and brain tissue. As cells disintegrate, they no longer pose a physical ...

'Microfluidic palette' may paint clearer picture of biological processes

... to study the complex biological mechanisms in cells responsible for cancer metastasis, wound healing, ... of currents. Diffusion gradients allow cells being studied to remain in the microchamber ... chemical molecules to move in and out of the cells naturally and eliminates the risk of shear ...

Reprogramming human cells without inserting genes

... discovery opens a new avenue for reprogramming cells that could eventually lead to treatments for a ... and traumatic injuries by coaxing a patient's own cells to repair and regenerate the damaged tissues. ... track" paper from the journal Cloning and Stem cells . "We show that by manipulating culture ...

Stem cell research: From molecular physiology to therapeutic applications

... disease to paralysis. Totipotent embryonic stem cells have great potential for generating a wide range of different human cells that can be used to restore malfunctioning or damaged cells and tissues in patients. Recent studies have ...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... messenger RNA and then proteins. Studies in both cells and a mouse model for cancer showed that they could promote the expression of MYC by transfecting cells with DNA strands containing DLX5. Too much DLX5, ... of MYC, they found they could turn those cells cancerous again. From this, Testa and Xu were ...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... cancer vaccines derived from patients' own cancer cells and immune cells were well tolerated and resulted in impressive ... The study entitled "Phase II Trial of Dendritic cells Loaded with Antigens from Self-Renewing, ...

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... to several types of immature and maturing cells that give rise to this cancer. James Downing, ... the push to chart the genetic changes that free cells from normal controls and allow the uncontrolled ... For this study, researchers analyzed leukemia cells from 111 St. Jude AML patients representing the ...

Study reveals a reprogrammed role for the androgen receptor

... One such gene, called UBE2C, which causes cells to ignore a natural pause in the division ... progresses normally; without it, daughter cells may grow even more aggressively and be harder to ... external androgen. One of the ways such cells re-start their growth is by producing their own ...

Placenta-derived stem cells may help sufferers of lung diseases

... , has found that stem cells derived from human placenta may ultimately play a ... the fibrotic process. Placenta-derived stem cells are known to be able to engraft in solid organs, including the lungs. Human term placenta stem cells also demonstrate characteristics of high ...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

... off or left on in healthy versus cancerous cells could enable early screening for many common ... in healthy colon, breast, brain and lymphatic cells and their cancerous counterpart to find telltale ... of the aberrant adjustments that enable cancer cells to thrive. Epigenetic changes actually are more ...

Scientists track impact of DNA damage in the developing brain

... also provides the first evidence that cells known as cerebellar interneurons are targeted for ... system. While the results suggest certain brain cells are particularly vulnerable, investigators report ... to single-strand DNA damage. Because brain cells do not divide, they cannot use the backup repair ...

Researchers capture bacterial infection on film

... dish. "In the body, immune surveillance cells such as hemocytes (or macrophages in vertebrates) ... a battery of signals from different sources. The cells integrate these signals and react to them accordingly. "Once these cells are removed from this complex environment and ...

Common allergy drug reduces obesity and diabetes in mice

... stabilize a population of inflammatory immune cells called mast cells. In the second study, ... in fat tissue of inflammatory immune cells called macrophages. "It seems that we're ... abnormalities in the insulin-producing beta cells of the pancreas, but their root causes are ...

Scientists closer to making implantable bone material, thanks to new research

... in the laboratory from different types of bone cells and stem cells. All of these cell types are ... 'bone-like' materials that were grown from bone cells from mouse skull and mouse bone marrow stem cells successfully mimicked many of the hallmarks of ...

Airway cells use 'tasting' mechanism to detect and clear harmful substances

... the scientists showed that, unlike taste cells on the tongue, these airway cells do not need help from the nervous system to ... is the first to show that motile cilia on airway cells not only have this "clearing" function, but also ...

Protein that promotes cancer cell growth identified

... helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding ... showed that Caspase-8 caused neuroblastoma cancer cells to proliferate and migrate. For the first time, ... same signaling pathway stimulates neuroblastoma cells to migrate and invade neighboring tissues--a ...

What scientists know about jewel beetle shimmer

... because of the light-reflecting properties of the cells that make up their external skeletons, not ... external skeleton, its five, six and seven sided cells spontaneously arrange themselves to reflect light ... colors. Srinivasarao postulates that beetle cells form similar to a certain kind of liquid crystal ...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

... genes -- may be at the root of what causes cancer cells to grow more quickly than normal cells. The ... expands our understanding of how prostate tumor cells can hijack androgen-regulated genes by using ... of messenger RNA -- the message that all cells produce -- the computational team, lead by Dr. ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... in the chemical reactions that take place within cells to convert biochemical energy into usable energy. ... are rare, generally benign tumors that arise from cells called glomus cells, which are located along ... an enzyme complex involved in the ability of cells to extract energy from nutrients. Studies in ...

Scientists link immune system's natural killer cells to infant liver disease

... weapons against infection natural killer, or NK, cells to the onset of biliary atresia in infants, a ... also report that blocking a gene that helps NK cells attack bile duct tissues lessens damage and may ... to block the disease by targeting certain cells or pro-inflammatory circuits," said Jorge A. ...

A genetic basis for schizophrenia

... in development, particularly the migration of cells to their proper location in the brain and ... into their intended fate. During development, cells need to properly migrate to their final ... integrate into the corresponding network of cells and function properly. Disruption of cell ...

Researchers design first model motor nerve system that's insulated and organized like the human body

... recognized the need for lab-grown motor nerve cells that myelinate and form nodes of Ranvier in order ... techniques for growing various nervous system cells in serum-free media, including motoneurons, and ... with for many years. In the body, nerve cells grow in two distinct environments: In the ...

International research team seeks to unravel flatworm regeneration

... lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm ... Schmidtea mediterranea. Full 30 percent of the cells of this species consists of stem cells, making it ... The researchers looked for small RNAs in stem cells as well as in the whole planarian organism. They ...

Skin-like tissue developed from human embryonic stem cells

... the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues ... outside of the body using new sources of stem cells such as hESC, with the goal of advancing ... in structure to those constructed using mature cells derived from newborn skin, which are the current ...

The right messenger for a healthy immune response

... immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells. As a consequence, these cells will not recognize the pathogen and the immune ... of Immunology . During an infection, immune cells produce Beta-Inferferon. Interestingly, an immune ...

Study by NTU professors provides important insight into apoptosis or programmed cell death

... to the understanding of the process that cells go through when they die. This process known as ... in the human body which removes perhaps a million cells a second. According to Professor Li, they ... When programmed cell death does not work right, cells that should be eliminated may linger around and ...

A matter of density, not quantity

... penetrating. The process of quorum sensing, which cells use to "sense" cell density, is triggered when ... has now demonstrated that the absolute number of cells is irrelevant; only the number of bacteria in a ... to trigger quorum-sensing processes in single cells when these were confined in extremely small ...

New lab test offers better prediction of HIV microbicide safety

... primarily for signs that the chemical inflames cells of the vaginal lining, or epithelium. That could ... good: When the epithelium becomes inflamed, T cells flock to the damaged area which might actually encourage HIV infection, since T cells are the main targets of HIV. Dr. Herold ...

Spontaneous assembly

... lipids, nucleic acids, etc. - are arranged. For cells to thrive, the organization of these components ... for succeeding generations of cells. Eukaryotic cells feature distinct subcellular structures, such as ... interiors and membranes," said Liphardt. "Two cells which are biochemically identical can have very ...
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(Date:9/15/2014)... fears that reef biodiversity may not provide the level ... , In an international study published today, Professor David ... Reef Studies (Coral CoE) says we need to identify ... , In coral reefs, just as in any modern-day ... safe and functioning. , Professor Bellwood says, in ...
(Date:9/15/2014)... vision document, released today by the National Academy ... goals, objectives, and strategies for the program and ... next five years (2015-2020). In addition, the ... be funded in 2015, will include exploratory grants, ... , The $500 million, 30-year program to be ...
(Date:9/15/2014)... Conditions on Earth for the first 500 million years ... the present day, complete with oceans, continents and active ... geologic eon, called the Hadean, has gained substantial new ... that formed more than 4 billion years ago with ... as a possible geological analog for early Earth. , ...
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(Date:9/15/2014)... 2014 Array Health , ... today announced that Independence Blue Cross ... Pennsylvania, has selected the Array Spectrum™ Private Exchange ... marketplace for employers with more than 100 employees. ... Independence will offer employer groups a comprehensive selection ...
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(Date:9/15/2014)... (PRWEB) September 15, 2014 Physicians ... this week, September 17-20, at the Lowes Coronado ... Plant-based Nutrition Healthcare Conference . This CME ... dietary-related advice—our physicians and healthcare professionals—about the nutritional ... food, plant-based nutrition and its proven ability to ...
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(Date:9/15/2014)... sensitive means of analyzing very tiny amounts of DNA. ... forensic scientists to match genetic material in some criminal ... painful, invasive test given to transplant patients at risk ... a blood test that reveals traces of donor DNA. ... of The Journal of Molecular Diagnostics , the ...
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