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Cardiac in Biological News

NIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections

... which come from the bone marrow, to regenerate cardiac tissue, thereby helping a damaged heart beat more ... Heart attacks cause significant scaring of cardiac tissue, which in turn prevents the scarred area ... injected into a damaged heart, they help improve cardiac function. Working with WPI colleagues George ...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

... marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure. Using an ... myocytes, or heart cells, by two-fold and reduced cardiac tissue injury by 60 percent. The therapy also ... MSCs and host tissues, culminating in effective cardiac repair for the failing heart." The paper ...

Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives

... medical history and a resting ECG. A second cardiac autopsy of the SUD victim was undertaken if ... and try to prevent their succumbing to sudden cardiac death. "The scale of heart disease that we ... identification of more families at risk of sudden cardiac death, in which preventive measures then can be ...

Genetic factors may predict depression in heart disease patients

... genetic study of depressive symptoms in cardiac patients. "Depression can significantly impact ... patients and can increase the risk for additional cardiac events or even death," said lead author Jeanne M. ... for the greater prevalence of depression among cardiac patients, including the stress of a poor ...

Gladstone scientists identify key factors in heart cell creation

... combination of factors has been found to activate cardiac differentiation in mammalian cells or tissues. ... complexes have severe heart defects and defective cardiac differentiation. These observations prompted us ... heart, and other tissues, specifically into cardiac muscle cells (cardiomyocytes) that beat ...

Researchers identify a molecule that increases the risk of cardiac insufficiency

... has identified a key enzyme in the development of cardiac insufficiency. This enzyme is involved in the ... tissues in the hearts of patients with chronic cardiac diseases and deterioration of heart functions. ... Research on Cardiovascular Diseases]. Today, cardiac insufficiency affects more than 1,250,000 Spanish ...

MDC researchers prevent virus induced myocarditis

... Life-threatening cardiac arrhythmia can be a consequence of myocarditis an inflammation of the cardiac muscle that can be caused by the Coxsackievirus. ... engineered mice without CAR were protected from cardiac infection caused by the Coxsackievirus. Moreover, ...

Targeted drug therapy prevents exercise-induced arrhythmias

... bedridden for three years because of an inherited cardiac arrhythmia syndrome can now join his friends on ... or stress, and are at risk for fainting and cardiac arrest. The syndrome kills up to 50 percent of ... and it may account for some unexplained sudden cardiac deaths in young athletes. Current treatment has ...

Hebrew University professor's work leads to FDA approval for product

... (FDA) of a product for use in pediatric cardiac surgery patients. The product is the result ... is of special concern, since they may affect cardiac function. Furthermore, in the frequent cases ... repeat operations are required, adhesions obscure cardiac landmarks, making the procedure potentially ...

Common gene variants influence risk factor for sudden cardiac death

... variants related to a risk factor for sudden cardiac death. The report receiving early online release ... findings could eventually help to prevent sudden cardiac death and arrhythmia by limiting the use of ... results from medications leading to drug-induced cardiac arrhythmias and sudden death. This is a ...

Genetic risk factors identified for sudden cardiac death

... research consortium QTSCD (QT Interval and Sudden cardiac Death), Dr. Arne Pfeufer of the Institute of ... repolarization and raise or lower the risk of cardiac arrhythmias. In their study, the scientists ... investigation of common diseases such as sudden cardiac death." The provision of highly valid ...

Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death

... it proved lethal is characteristic of sudden cardiac death, which annually claims more than a quarter ... in the blood makes the prediction of sudden cardiac death largely dependent on genetic risk factors. ... prolonged or shortened, predisposes to sudden cardiac death. QT interval, which is determined from ...

Ten genes identified in connection with sudden cardiac death

... heart rhythms are a common cause of sudden cardiac death or SCD, a condition that accounts for ... identify genetic defects associated with sudden cardiac death. Aravinda Chakravarti of Johns Hopkins and ... problems, including arrhythmias and sudden cardiac death. The QT interval can be seen on an ...

Therapeutic hypothermia is promising strategy to minimize tissue damage

... operating room, and its role in the treatment of cardiac arrest, stroke and subarachnoid hemorrhage, ... After Resuscitation from Out-of-Hospital cardiac Arrest." Kochanek et al. collaborate on two ... the other focusing on applications in pediatric cardiac arrest. Shankaran presents "Neonatal ...

Why 'lazy Susan' has a weak heart

... suddenly collapse, it can be due to hereditary cardiac disease. Researchers at the Heidelberg University ... discovered a genetic modification that leads to cardiac weakness in an animal model. Just one "false" ... could be critical for humans as well. cardiac insufficiency is not just a disease that results ...

Sudden cardiac death without recognizable cause

... In about 10% of cases, sudden cardiac death (SCD) in young people is due to a cardiac gene defect. This was the conclusion drawn by ... Dtsch Arztebl Int 2009; 106(4): 41-7). Sudden cardiac death is defined as unexpected death occurring ...

Studies point to novel target for treating arrhythmias

... They strike without warning, causing sudden cardiac death, which accounts for about 10 percent of all ... (HCM), which carries a high risk of sudden cardiac death. HCM is perhaps most famous as a cause of sudden cardiac death in young athletes, but it can affect ...

UT faculty members win American Heart Association awards for advancing research

... which is an important cause of sudden cardiac death in the young, especially athletes. In this ... a genetic disorder, excessive fat cells replace cardiac myocytes in the heart, particularly the right ... of new therapies aimed at preventing the cardiac stem cells from switching a muscle fate to a fat ...

Life Sciences Discovery Fund awards health research program grants

... vaccine development, improving the potential of cardiac resuscitation technology, improving the delivery ... title: Program to Integrate Technology and cardiac Arrest Resuscitation Program focus: To improve cardiac resuscitation technology and resuscitation ...

Vitamin E shows possible promise in easing chronic inflammation

... vivo, might have similar effects on skeletal and cardiac muscle, Huey and a team of Illinois researchers ... on local inflammatory responses in skeletal and cardiac muscle. In this study, the researchers ... could be a good thing especially in terms of cardiac function." However, she said, "IL-6 can have ...

Damage inflicted during cardiac attacks more widespread, MSU researchers find

... crystals released in the bloodstream during a cardiac attack or stroke can damage artery linings much ... then be released into the circulation following a cardiac event," Abela said. "We found that the flow of ... to a tree, with the trunk as the site of the cardiac event and the branches representing arteries ...

Case Western Reserve University uncovers genetic basis for some birth defects

... to DiGeorge syndrome, which is associated with cardiac and palate defects. Interestingly, the ERK2 gene ... associated with a different distinct group of cardiac and craniofacial syndromes that include Noonan, ... distinct syndromes that are each characterized by cardiac and craniofacial abnormalities and show that they ...

Grapes may aid a bunch of heart risk factors, animal study finds

... Bolling, M.D. Bolling, who is a professor of cardiac surgery at the U-M Medical School, notes that the ... group. Finally, the grape-fed rats had improved cardiac output, or more blood pumped per unit of time. ... damage and other molecular indicators of cardiac stress. Again, the rats that received the ...

Research uncovers new steps on pathway to enlarged heart

... new strategies for managing this extremely common cardiac ailment that often leads to heart failure. ... leading to MEF2 are altered during pathological cardiac hypertrophy," says senior study author Dr. John ... identify the molecular mechanisms associated with cardiac hypertrophy, Dr. Scott and colleagues ...

Embryonic heart exhibits impressive regenerative capacity

... diseased cells represented only about 10% of the cardiac tissue. The authors went on to show that ... functional heart. Nevertheless, despite normal cardiac function early in life, over 40% of adult mice prematurely developed cardiac pathologies which may indicate a hitherto ...

New mechanism for cardiac arrhythmia discovered

... long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. ... electric signals that control the heart beat. cardiac arrhythmia occurs when these signals are not ... no longer produce the receptors and developed cardiac arrhythmia. "That is an interesting observation ...

Early parenting plays key role in infants' physiological response to stress

... they were exposed to the stressor, isolating a cardiac response called vagal tone. Vagal tone acts like ... of the way in which the brain helps regulate cardiac responses to stress. At 3 and 6 months old, those ... risky behaviors did not display an effective cardiac response to the stressor (a decrease in vagal ...

Syntermed licenses Emory ERTb software for enhanced cardiac imaging

... generating "front end" for the widely used Emory cardiac Toolbox™, a vast set of software tools for evaluating cardiac images, developed by Garcia and his colleagues at ... and elsewhere over the past 20 years. The Emory cardiac Toolbox is used in almost half of ...

Cardiac cell transplant studies show promise in cardiac tissue repair

... transplanting cardiomyocytes alone. First, while cardiac function was preserved by implanting ... if protection against apoptosis was successful. cardiac function was measured before and 28 days after ... delineate the evolving role of bone marrow in cardiac cell therapy, not only as a regenerative means ...

CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics

... prey, as models for new therapeutics to treat cardiac diseases. Hiberna Corp., a Boulder-based ... help researchers target new drugs for treating cardiac growth in response to disease, which causes human ... Cardiovascular Institute. Increases in cardiac size are clinically important because heart ...

Latest advances in interventional cardiology for congenital heart disease presented

... 20-23 for the Pediatric & Adult Interventional cardiac Symposium (PICS/AICS). Specialists from Rush ... Hijazi, Michel Ilbawi, chief of Pediatric cardiac Surgery, and Zahid Amin, interventional ... to shorten the duration of bed rest following cardiac catheterization procedures, the safety of patent ...

New source of heart stem cells discovered

... on June 22, comes on the heels of parallel cardiac stem cell discoveries in 2006, at both Children's ... cells can also be derived from a third type of cardiac progenitor, located within the epicardium and ... stem cells express throughout the body, with no cardiac or developmental specificity. "I think our ...

Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure

... Blood Institute to study molecular mechanisms of cardiac injury that lead to heart failure and potential ... are small cells that appear to come from resident cardiac stem cells. These heart cells depend on the (T) ... drugs to better understand how they affect cardiac stem cells. ...

UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells

... researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been ... immature heart cells that can give rise to mature cardiac cells that perform different functions. The ... iPS cell lines to provide cells for cardiac repair and regeneration, MacLellan said. It ...

Saliva can help diagnose heart attack, study shows

... helping save lives and prevent damage from cardiac disease. The device is the size of a credit card ... help too late after permanent damage to the cardiac tissue has occurred, says John T. McDevitt, ... to dramatically improve the accuracy and speed of cardiac diagnosis. McDevitt, a professor of chemistry ...

Exercise during pregnancy leads to a healthier heart in moms- and babies-to-be

... pregnancy can have a beneficial effect on fetal cardiac programming by reducing fetal heart rate and ... variability, the MCG allows for the study of the cardiac waveforms to measure of cardiac time intervals. For the study, fetal ...

Improved foam for varicose veins found to be safe in preliminary results from phase II trial

... microfoam experienced no neurological, visual or cardiac changes as a result of the treatment, according ... examinations and examinations for changes in cardiac markers in the blood. During the procedure, a ... procedure. However, no neurological, visual or cardiac changes were observed in the monitoring. The ...

Taking the fight against cancer to heart

... Physiological Society. The discovery of cardiac hormones For more than 350 years, scientists ... failure research Vesely began his research on cardiac hormones by looking at the role they can play in ... The symposium that Vesely will moderate, cardiac hormones for the treatment of acute myocardial ...

Carbon monoxide may cause long-lasting heart damage

... hearts pumping capacity and permanently impairs cardiac function. These findings suggest that heart ... in order to determine the direct effects of CO on cardiac function in the recovery phase. This model used ... However, the group exposed to CO did not recover cardiac function including blood pressure to the extent ...

Cell Therapy for Cardiovascular Diseases

... cells, raising new potential for regenerating cardiac muscle after a heart attack First-ever ... of clinical trials Special Sessions on: cardiac Tissue Engineering, including exciting work in ... M.D., Conference Director, is Director of cardiac Cell-Based Endovascular Therapies at the Center ...
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(Date:8/20/2014)... Women who are poor experience higher cortisol levels in ... of the stress hormone, putting them at greater ... a new research from the University of Colorado Denver. ... American Journal of Human Biology , is the first ... to the socioeconomic status of their mothers during pregnancy. ...
(Date:8/20/2014)... developed by researchers at the University of Missouri School ... a life-threatening heart condition caused by muscular dystrophy. ... Lai, Ph.D., the leading author of the study and ... Department of Molecular Microbiology and Immunology. "This is just ... to a treatment for people with this devastating heart ...
(Date:8/20/2014)... grows to about 4,000 members, it triggers an important ... a special type of comb used for rearing male ... Department of Neurobiology and Behaviour at Cornell University, led ... of honeybee colonies. The results are published in Springer,s ... , Reproduction isn,t always a honeybee colony,s top ...
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