NIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections
... which come from the bone marrow, to regenerate cardiac
tissue, thereby helping a damaged heart beat more ... Heart attacks cause significant scaring of cardiac
tissue, which in turn prevents the scarred area ... injected into a damaged heart, they help improve cardiac
function. Working with WPI colleagues George ...
Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue
... marrow stem cells into skeletal muscle can repair cardiac
tissue, reversing heart failure.
Using an ... myocytes, or heart cells, by two-fold and reduced cardiac
tissue injury by 60 percent.
The therapy also ... MSCs and host tissues, culminating in effective cardiac
repair for the failing heart."
The paper ...
Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives
... medical history and a resting ECG. A second cardiac
autopsy of the SUD victim was undertaken if ... and try to prevent their succumbing to sudden cardiac
death. "The scale of heart disease that we ... identification of more families at risk of sudden cardiac
death, in which preventive measures then can be ...
Genetic factors may predict depression in heart disease patients
... genetic study of depressive symptoms in cardiac
"Depression can significantly impact ... patients and can increase the risk for additional cardiac
events or even death," said lead author Jeanne M. ... for the greater prevalence of depression among cardiac
patients, including the stress of a poor ...
Gladstone scientists identify key factors in heart cell creation
... combination of factors has been found to activate cardiac
differentiation in mammalian cells or tissues. ... complexes have severe heart defects and defective cardiac
differentiation. These observations prompted us ... heart, and other tissues, specifically into cardiac
muscle cells (cardiomyocytes) that beat ...
Researchers identify a molecule that increases the risk of cardiac insufficiency
... has identified a key enzyme in the development of cardiac
insufficiency. This enzyme is involved in the ... tissues in the hearts of patients with chronic cardiac
diseases and deterioration of heart functions.
... Research on Cardiovascular Diseases].
insufficiency affects more than 1,250,000 Spanish ...
MDC researchers prevent virus induced myocarditis
... Life-threatening cardiac
arrhythmia can be a consequence of myocarditis an inflammation of the cardiac
muscle that can be caused by the Coxsackievirus. ... engineered mice without CAR were protected from cardiac
infection caused by the Coxsackievirus. Moreover, ...
Targeted drug therapy prevents exercise-induced arrhythmias
... bedridden for three years because of an inherited cardiac
arrhythmia syndrome can now join his friends on ... or stress, and are at risk for fainting and cardiac
arrest. The syndrome kills up to 50 percent of ... and it may account for some unexplained sudden cardiac
deaths in young athletes.
Current treatment has ...
Hebrew University professor's work leads to FDA approval for product
... (FDA) of a product for use in pediatric cardiac
The product is the result ... is of special concern, since they may affect cardiac
function. Furthermore, in the frequent cases ... repeat operations are required, adhesions obscure cardiac
landmarks, making the procedure potentially ...
Common gene variants influence risk factor for sudden cardiac death
... variants related to a risk factor for sudden cardiac
death. The report receiving early online release ... findings could eventually help to prevent sudden cardiac
death and arrhythmia by limiting the use of ... results from medications leading to drug-induced cardiac
arrhythmias and sudden death. This is a ...
Genetic risk factors identified for sudden cardiac death
... research consortium QTSCD (QT Interval and Sudden cardiac
Death), Dr. Arne Pfeufer of the Institute of ... repolarization and raise or lower the risk of cardiac
arrhythmias. In their study, the scientists ... investigation of common diseases such as sudden cardiac
The provision of highly valid ...
Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death
... it proved lethal is characteristic of sudden cardiac
death, which annually claims more than a quarter ... in the blood makes the prediction of sudden cardiac
death largely dependent on genetic risk factors. ... prolonged or shortened, predisposes to sudden cardiac
QT interval, which is determined from ...
Ten genes identified in connection with sudden cardiac death
... heart rhythms are a common cause of sudden cardiac
death or SCD, a condition that accounts for ... identify genetic defects associated with sudden cardiac
death. Aravinda Chakravarti of Johns Hopkins and ... problems, including arrhythmias and sudden cardiac
death. The QT interval can be seen on an ...
Therapeutic hypothermia is promising strategy to minimize tissue damage
... operating room, and its role in the treatment of cardiac
arrest, stroke and subarachnoid hemorrhage, ... After Resuscitation from Out-of-Hospital cardiac
Arrest." Kochanek et al. collaborate on two ... the other focusing on applications in pediatric cardiac
arrest. Shankaran presents "Neonatal ...
Why 'lazy Susan' has a weak heart
... suddenly collapse, it can be due to hereditary cardiac
disease. Researchers at the Heidelberg University ... discovered a genetic modification that leads to cardiac
weakness in an animal model. Just one "false" ... could be critical for humans as well.
insufficiency is not just a disease that results ...
Sudden cardiac death without recognizable cause
... In about 10% of cases, sudden cardiac
death (SCD) in young people is due to a cardiac
gene defect. This was the conclusion drawn by ... Dtsch Arztebl Int 2009; 106(4): 41-7).
death is defined as unexpected death occurring ...
Studies point to novel target for treating arrhythmias
... They strike without warning, causing sudden cardiac
death, which accounts for about 10 percent of all ... (HCM), which carries a high risk of sudden cardiac
death. HCM is perhaps most famous as a cause of sudden cardiac
death in young athletes, but it can affect ...
UT faculty members win American Heart Association awards for advancing research
... which is an important cause of sudden cardiac
death in the young, especially athletes. In this ... a genetic disorder, excessive fat cells replace cardiac
myocytes in the heart, particularly the right ... of new therapies aimed at preventing the cardiac
stem cells from switching a muscle fate to a fat ...
Life Sciences Discovery Fund awards health research program grants
... vaccine development, improving the potential of cardiac
resuscitation technology, improving the delivery ... title: Program to Integrate Technology and cardiac
Program focus: To improve cardiac
resuscitation technology and resuscitation ...
Vitamin E shows possible promise in easing chronic inflammation
... vivo, might have similar effects on skeletal and cardiac
muscle, Huey and a team of Illinois researchers ... on local inflammatory responses in skeletal and cardiac
In this study, the researchers ... could be a good thing especially in terms of cardiac
However, she said, "IL-6 can have ...
Damage inflicted during cardiac attacks more widespread, MSU researchers find
... crystals released in the bloodstream during a cardiac
attack or stroke can damage artery linings much ... then be released into the circulation following a cardiac
event," Abela said. "We found that the flow of ... to a tree, with the trunk as the site of the cardiac
event and the branches representing arteries ...
Case Western Reserve University uncovers genetic basis for some birth defects
... to DiGeorge syndrome, which is associated with cardiac
and palate defects. Interestingly, the ERK2 gene ... associated with a different distinct group of cardiac
and craniofacial syndromes that include Noonan, ... distinct syndromes that are each characterized by cardiac
and craniofacial abnormalities and show that they ...
Grapes may aid a bunch of heart risk factors, animal study finds
... Bolling, M.D.
Bolling, who is a professor of cardiac
surgery at the U-M Medical School, notes that the ... group. Finally, the grape-fed rats had improved cardiac
output, or more blood pumped per unit of time. ... damage and other molecular indicators of cardiac
stress. Again, the rats that received the ...
Research uncovers new steps on pathway to enlarged heart
... new strategies for managing this extremely common cardiac
ailment that often leads to heart failure.
... leading to MEF2 are altered during pathological cardiac
hypertrophy," says senior study author Dr. John ... identify the molecular mechanisms associated with cardiac
hypertrophy, Dr. Scott and colleagues ...
Embryonic heart exhibits impressive regenerative capacity
... diseased cells represented only about 10% of the cardiac
The authors went on to show that ... functional heart. Nevertheless, despite normal cardiac
function early in life, over 40% of adult mice prematurely developed cardiac
pathologies which may indicate a hitherto ...
New mechanism for cardiac arrhythmia discovered
... long been thought that virus infections can cause cardiac
arrhythmia. But why has not been understood. ... electric signals that control the heart beat. cardiac
arrhythmia occurs when these signals are not ... no longer produce the receptors and developed cardiac
arrhythmia. "That is an interesting observation ...
Early parenting plays key role in infants' physiological response to stress
... they were exposed to the stressor, isolating a cardiac
response called vagal tone. Vagal tone acts like ... of the way in which the brain helps regulate cardiac
responses to stress. At 3 and 6 months old, those ... risky behaviors did not display an effective cardiac
response to the stressor (a decrease in vagal ...
Syntermed licenses Emory ERTb software for enhanced cardiac imaging
... generating "front end" for the widely used Emory cardiac
Toolbox™, a vast set of software tools for evaluating cardiac
images, developed by Garcia and his colleagues at ... and elsewhere over the past 20 years. The Emory cardiac
Toolbox is used in almost half of ...
Cardiac cell transplant studies show promise in cardiac tissue repair
... transplanting cardiomyocytes alone. First, while cardiac
function was preserved by implanting ... if protection against apoptosis was successful.
function was measured before and 28 days after ... delineate the evolving role of bone marrow in cardiac
cell therapy, not only as a regenerative means ...
CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
... prey, as models for new therapeutics to treat cardiac
Hiberna Corp., a Boulder-based ... help researchers target new drugs for treating cardiac
growth in response to disease, which causes human ... Cardiovascular Institute.
Increases in cardiac
size are clinically important because heart ...
Latest advances in interventional cardiology for congenital heart disease presented
... 20-23 for the Pediatric & Adult Interventional cardiac
Symposium (PICS/AICS). Specialists from Rush ... Hijazi, Michel Ilbawi, chief of Pediatric cardiac
Surgery, and Zahid Amin, interventional ... to shorten the duration of bed rest following cardiac
catheterization procedures, the safety of patent ...
New source of heart stem cells discovered
... on June 22, comes on the heels of parallel cardiac
stem cell discoveries in 2006, at both Children's ... cells can also be derived from a third type of cardiac
progenitor, located within the epicardium and ... stem cells express throughout the body, with no cardiac
or developmental specificity.
"I think our ...
Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure
... Blood Institute to study molecular mechanisms of cardiac
injury that lead to heart failure and potential ... are small cells that appear to come from resident cardiac
stem cells. These heart cells depend on the (T) ... drugs to better understand how they affect cardiac
UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells
... researchers at UCLA were able to grow functioning cardiac
cells using mouse skin cells that had been ... immature heart cells that can give rise to mature cardiac
cells that perform different functions. The ... iPS cell lines to provide cells for cardiac
repair and regeneration, MacLellan said.
Saliva can help diagnose heart attack, study shows
... helping save lives and prevent damage from cardiac
disease. The device is the size of a credit card ... help too late after permanent damage to the cardiac
tissue has occurred, says John T. McDevitt, ... to dramatically improve the accuracy and speed of cardiac
McDevitt, a professor of chemistry ...
Exercise during pregnancy leads to a healthier heart in moms- and babies-to-be
... pregnancy can have a beneficial effect on fetal cardiac
programming by reducing fetal heart rate and ... variability, the MCG allows for the study of the cardiac
waveforms to measure of cardiac
For the study, fetal ...
Improved foam for varicose veins found to be safe in preliminary results from phase II trial
... microfoam experienced no neurological, visual or cardiac
changes as a result of the treatment, according ... examinations and examinations for changes in cardiac
markers in the blood.
During the procedure, a ... procedure. However, no neurological, visual or cardiac
changes were observed in the monitoring. The ...
Taking the fight against cancer to heart
... Physiological Society.
The discovery of cardiac
For more than 350 years, scientists ... failure research
Vesely began his research on cardiac
hormones by looking at the role they can play in ...
The symposium that Vesely will moderate, cardiac
hormones for the treatment of acute myocardial ...
Carbon monoxide may cause long-lasting heart damage
... hearts pumping capacity and permanently impairs cardiac
These findings suggest that heart ... in order to determine the direct effects of CO on cardiac
function in the recovery phase. This model used ... However, the group exposed to CO did not recover cardiac
function including blood pressure to the extent ...
Cell Therapy for Cardiovascular Diseases
... cells, raising new potential for regenerating cardiac
muscle after a heart attack
First-ever ... of clinical trials
Special Sessions on:
Tissue Engineering, including exciting work in ... M.D., Conference Director, is Director of cardiac
Cell-Based Endovascular Therapies at the Center ...