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Cancers in Biological News

Moving to the US increases cancer risk for Hispanics

... groups have higher incidence rates of certain cancers and worse cancer outcomes if they live in the ... Pinheiro and colleagues evaluated the kinds of cancers occurring in each Hispanic population group and ... seemed to acquire higher risk for diet-related cancers relatively quickly. Furthermore, Cuban males ...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

... could enable early screening for many common cancers and maybe help avoid them, Medical College of ... study at MCG and other centers for a variety of cancers and blood disorders. Because tumor cells that ... non-invasive screening for a wide range of cancers could result be another result of this ...

$2 million grant aids study of lung cancer in people who never smoked

... the country. "We know that smoking-related cancers are heavily dependent on how much one smokes. The ... suggest that as many as 25 percent of all lung cancers worldwide 15 percent of those in men and 50 ... smoking, their cancer more closely resembles cancers from never-smokers than from smokers," Dr. Gazdar ...

Possible drug target found for one of the most aggressive breast cancers

... of breast cancer. Currently, patients with these cancers have few treatment options. "Breast cancer mortality rates are actually declining, but the cancers that don't respond to traditional treatments tend ... signaling is implicated in most types of human cancers and high Met expression often correlates with ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

... in survival based on race for a number of cancers including lung, colon, lymphoma, leukemia and ... patients with breast, ovarian, or prostate cancers the gender specific tumors were found to face a ... the metabolism of chemotherapy drugs or that make cancers more resistant or more aggressive. We are now ...

New early detection studies of lung cancer in non-smokers launched today

... suggest that as many as 25 percent of all lung cancers worldwide 15 percent of those in men and 50 ... cause of cancer deaths worldwide, even before cancers of the cervix, pancreas and prostate," commented ... Studies of Lung Cancer Cell Lines from Lung cancers Arising in Current, and Never Smokers (PIs: Lam ...

New diagnostic advance seen for head, throat cancer

... of the cancer. Head and neck squamous cell cancers are the sixth most common cancers in the world, the researchers said in their study, and a significant cause of mortality. In 2008, cancers of the oral cavity and pharynx alone accounted ...

Agent Orange exposure increases veterans' risk of aggressive recurrence of prostate cancer

... "There is something about the biology of these cancers that are associated with prior Agent Orange ... only are their recurrence rates higher but their cancers are coming back and growing much faster when they ... showed recurrence rates were higher and recurring cancers were more aggressive with Agent Orange exposure. ...

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

... approximately a third of the 250 human pancreatic cancers studied. In a presentation April 18, at ... a new treatment for a large subset of pancreatic cancers and a potential blood or urine screening tool ... is activated only in a subset of all pancreatic cancers cannot be a one-size-fits-all target for ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

... Thirty-five percent of non-small-cell lung cancers have this protein which also is present in some ... A total of 182 patients with non-small-cell lung cancers were included in the early phase of the study ... the vaccine therapy. All the patients had cancers expressing MAGE-A3, the tumor-specific antigen. ...

Two-day symposium in Baltimore to tackle the promises and perils of proton radiotherapy

... proton therapy lowers the risk of secondary cancers later in life. What does the scientific ... these theoretical advantages in the treatment of cancers of the lungs, skull, and prostate. The technology ... promising for treating small, shallow cancers near the eyes and spine, and for tumors in ...

Getting down to cancer basics

... a new cancer gene - one that is common to many cancers and affects the most basic regulation of our ... gene regulation and shows the depths to which cancers will plumb in order to get themselves ready to ... attempts to comprehensively describe different cancers which will to lead to expanding opportunities to ...

Grape-seed extract kills laboratory leukemia cells, proving value of natural compounds

... no one had tested the extract in hematological cancers nor had the precise mechanism for activity been ... say this is chemo-protective." Hematological cancers leukemia, lymphoma and myeloma accounted for an ... and almost 54,000 deaths in 2006, ranking these cancers as the fourth leading cause of cancer incidence ...

GUMC researchers find gene function 'lost' in melanoma and glioblastoma

... a gene they say is inactivated in two aggressive cancers malignant melanoma, a form of skin cancer, and ... been found to be inactivated in several other cancers as well, their discovery suggests that PTPRD may ... loss of PTPRD in a number of additional cancers then it may be possible to design a therapy that ...

Prostate cancer spurs new nerves

... Prostate cancer and perhaps other cancers promotes the growth of new nerves and the ... target in prostate cancer treatment, as prostate cancers are more aggressive when neurogenesis is ... global phenomenon, particularly relating to those cancers that grow along nerve paths," said Ayala, also a ...

Viral 'magic bullet' targets cancer cells with help of new compound

... However, Dr. Hiscott explained, many primary cancers have proven resistant to a pure virotherapy ... increases the susceptibility of these cancers to killing by the oncolytic virus," Dr. Hiscott ... for breast, prostate, colon and other primary cancers that are currently resistant to virotherapy. ...

CSHL scientists identify new drug target against virulent type of breast cancer

... of using ErbB2 inhibitors alone to treat breast cancers has fallen short," noted Dr. Muthuswamy. "These ... out that the over-production of ErbB2 in breast cancers is due to a gene mutation that results in the ... in a majority of breast cancers. As some of these cancers also over-express ErbB2, the CSHL team wondered ...

Cancer signatures uncovered

... open access journal Genome Biology, describes how cancers can be divided into three groups distinguished by ... human tissues and those expressed in different cancers affecting these tissues. He says, "Our study ... studies". One of the three described groups of cancers has an early developmental phenotype and ...

Scientists discover major genetic cause of colorectal cancer

... CHICAGO -- About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer ... "This probably accounts for more colorectal cancers than all other gene mutations discovered thus ...

'Smothered' genes combine with mutations to yield poor outcome in cancer patients

... identified a set of genes in breast and colon cancers with a deadly combination of traditional ... could be inactivated in a broader range of cancers as well. That means the current findings could ... information will provide new details about why cancers start and help us identify ...

Control switches found for immune cells that fight cancer, viral infection

... of natural killer (NK) cells, which kill early cancers and fight off viral infections. The protein ... "NK cells are very good at nipping early cancers in the bud," says Cooper. "If we can better ... lead us to ways to make them better killers of cancers and cells infected by viruses and other ...

Estrogen helps drive distinct, aggressive form of prostate cancer

... of two genes. "Fifty percent of prostate cancers harbor a common recurrent gene fusion, and we ... that distinguishes fusion-positive TMPRSS2-ERG cancers from other prostate malignancies." A close ... Research into just why fusion-positive prostate cancers are so aggressive -- and potential molecular drug ...

New type of drug shrinks primary breast cancer tumors significantly in just 6 weeks

... breast cancer stem cells in the primary breast cancers of women receiving neoadjuvant treatment ... preoperative chemotherapy; indeed, residual cancers that were exposed to such chemotherapy showed an ... This finding should also apply to other types of cancers and research of tumour-initiating stem cells in ...

Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors

... regimens than did women with sporadic breast cancers that were not associated with BRCA1/2. Women ... seems to work better in BRCA1/2 breast cancers than in sporadic cancers is due to the lack of a working BRCA1/2 protein. ...

How what and how much we eat (and drink) affects our risk of cancer

... cancer. The researchers found that ER+/PR+ cancers showed a stronger association with alcohol than ... and control of obesity-related epithelial cancers in humans," said John DiGiovanni, Ph.D., director ... and progression. Folic acid may prevent new cancers in the colorectum, said Karen K. Sie, a graduate ...

'Swish-and-spit' test accurate for cancer

... neck cancer patients and 527 individuals without cancers of the mouth, larynx or pharynx to brush the ... cells, says Califano. Because head and neck cancers are not widespread, it makes more sense to screen ... tobacco and alcohol use. Other head and neck cancers are caused by the sexually transmitted human ...

New study reveals for first time how BRCA1 mutations cause breast cancer

... involved in the repair of such damage. In breast cancers from women with normal BRCA1, such large ... Finding May Affect 50% of BRCA1 Breast cancers & Lead to New Treatments Dr. Parsons estimates that about 50 percent of BRCA1 breast cancers will be found to harbor mutated PTEN once a ...

Cleveland Clinic leading clinical program to improve early-stage lung cancer detection

... X-ray CAD can help identify hard to detect lung cancers at an early stage when they are most treatable, ... States annually than breast, prostate and colon cancers combined.* Eighty million chest X-rays are taken ... However, without chest X-ray CAD, many lung cancers may not be found or are overlooked when lung ...

A crystal ball for brain cancer?

... UCLA doctor prescribed the off-label use of Avastin, a drug shown to quell cancers in the breast, colon and lung. One month later, McNabb's tumors had ... is an expensive drug, yet only 50 percent of patients with recurring brain cancers respond to it," said lead author Dr. Whitney Pope, assistant professor of ...

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... the development of AML may require fewer genetic alterations than other cancers and that a very limited number of biological processes may need to be ... of AML, but there are very few lesions in total. That is surprising. Most cancers have lots of alterations," he explained. AML accounts for about 20 ...

Study reveals a reprogrammed role for the androgen receptor

... receptor directs a distinct gene pathway in androgen-independent prostate cancers may lead to the identification of genes in that pathway that can be targeted by future therapies." Prostate cancers whose growth is fed by androgen are commonly treated with ...

Research uncovers clues to virus-cancer link

... Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients. In an April article published in the journal PLoS ... in primary effusion lymphoma and Kaposi's Sarcoma. "We chose these two cancers because, while they are both associated with the same virus, they occur in ...

UCLA cancer researchers develop model that may help identify cancer stem cells

... breast cancer stem cells. Many scientists believe that most, if not all, cancers will one day be traced back to these stem cells. Only a small ... but a collection of sub-types with different characteristics. Some lung cancers are invasive and spread quickly throughout the body, while some become ...

Montana State grad's work helps diagnose skin cancer without a biopsy

... Society, most of those biopsies -- as many as 80 percent for some types of cancers -- come back negative. The handheld microscope could help doctors get a ... signature to a database containing the chemical signatures of known cancers to see whether the patient's cells are cancerous. The project, which ...

Skin cancer study uncovers new tumor suppressor gene

... to MMP-8. "We often talk about cancer as though it is one disease, and cancers do have many common denominators. But when we look at the DNA level, we see that different cancers have different genetic profiles, and so do different patients who have the ...

Small molecules block cancer gene

... and his colleagues started looking at Stat3, they knew it was important in cancers of the head and neck. Further research showed that it also was important in breast, lung and prostate cancers as well as multiple myeloma (a cancer affect blood-forming cells) and ...

National Lung Cancer Partnership and LUNGevity Foundation announce 2009 grant recipients

... in lung cancer. His research will focus on estrogen, which many lung cancers either make or are responsive to, similarly to breast cancer. Aromatase-inhibitors, drugs which turn off the enzyme aromatase which can cause some cancers to grow and have long been used in breast cancer treatment, will be ...

U-M researchers discover new genes that fuse in cancer

... gene fusions are thought to be the driving mechanism that causes certain cancers to develop. The gene fusions discovered could potentially serve as a ... Gene fusions had previously been known to play a role in blood cell cancers such as leukemia and lymphoma, and in Ewing's sarcoma. In the current ...

Cancer cell 'bodyguard' turned into killer

... drug target because its levels are elevated in a majority of human cancers and it is responsible for cancer cells' resistance to many ... act on Bcl-2 at the Nur77 binding site. "Quite conceivably, individual cancers may respond better to one type of Bcl-2 inhibitor than another," he said. ...

Mechanisms of cardiovascular disease and cancer give clues to new therapies

... to heart attacks and strokes are treated quite separately from common cancers of the prostate, breast or lung, but now turn out to involve some of the ... one of the most important molecular processes common to a number of cancers and cardiovascular disease, involving the pathway known as the endothelin ...
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(Date:7/30/2014)... is a subject of major interest in neuroscience. ... during the distinct stages of Wallerian degeneration: transcription ... dedifferentiation. Although gene expression responses in the distal ... injury are known, differences in gene expression between ... Dengbing Yao and co-workers from Nantong University, China ...
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