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Blood in Biological News

NIH stimulus funding supports Emory biomedical scientists

... projects at Emory thus far include: Blocking blood vessel growth in tumors: The creation of new blood vessels can be good a response to exercise or ... examines Syk, a molecule that appears to push blood vessels to grow in response to low oxygen. ...

Holding breath for several minutes elevates marker for brain damage

... researchers said. The release of S100B into the blood suggests that holding one's breath for a long ... diving often leads to hypoxia, elevated blood pressure, slowed heartbeat and other ... warm-ups. The researchers took arterial blood samples from a catheter inserted into the artery ...

La Jolla Institute discovers novel tumor suppressor

... disorders characterized by an overproduction of blood cells by the bone marrow and include chronic ... an "important" step in advancing understanding of blood cancers. "It's very interesting that this ... cell proliferation, survival and, in the case of blood stem cells, to promote the development of myeloid ...

A crystal ball for brain cancer?

... powerful drug shrinks tumors by choking off their blood supply. Half of patients don't respond to the ... of how the tumor creates an independent blood supply. Cancer cells secrete a growth factor called VEGF that spurs the growth of new blood vessels to supply the tumor with oxygen and ...

Experimental treatment halts hypoxic-ischemic brain injury in newborns

... the brains of newborns suffering from oxygen and blood flow deprivation stops a type of brain damage ... brain damage triggered by the lack of oxygen and blood supply. The experimental pre-clinical treatment ... down proteins and other molecules to eliminate blood clots. The current study, posted on the ...

Common allergy drug reduces obesity and diabetes in mice

... study, researchers found that a kind of white blood cell called a regulatory T cell, once thought to manage only other white blood cells, also acts as a liaison between the ... in wounded tissue, primarily by increasing blood flow to the site. However, in certain conditions ...

In vitro antibody production enables HIV infection detection in window period -- key to safer blood

... and Medicine , show that pre-treating the whole blood sample in the SMARTube containing immune ... otherwise be classified as HIV-1 seronegative blood donors. The identification of techniques that can ... levels of anti-HIV antibodies in the whole blood sample and to the detection of potentially ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... called glomus cells, which are located along blood vessels and play a role in regulating blood pressure and blood flow. Approximately 25 percent of paragangliomas ...

Penn-Wistar team gains insight into HIV vaccine failure

... These individuals were found to have high blood Ad5 neutralizing antibody (nAb) titers, the main ... and Wistar Institute Vaccine Center, analyzed blood samples from 40 healthy participants in the phase ... vaccine for immune response to Ad5 particles. The blood samples, which came from individuals with both ...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

... recommended by physicians to people with high blood pressure or pre-hypertension. The DASH diet eating plan has been proven to lower blood pressure in studies sponsored by the National Institutes of Health. High blood pressure is considered a risk factor for ...

Two dietary oils, two sets of benefits for older women with diabetes

... oil reduced fat in the trunk area, lowered blood sugar and increased muscle tissue in the women ... other medications, such as those used to manage blood sugar levels, cholesterol or blood pressure. The women were randomized into two ...

Natural compound stops retinopathy

... of the compound's function in inflammation and blood vessel formation related to eye disease means ... in American adults. It is caused by changes in blood vessels of the retina, the light-sensitive tissue ... eye. In some people with diabetic retinopathy, blood vessels may swell and leak fluid. In other ...

Brain malformations significantly associated with preterm birth, Wake Forest research shows

... on studying coagulopathy (a tendency to excessive blood coagulation and formation of blood clots) to find what the association is between ... associated with preterm birth, there may be blood clots coming from the placenta, causing brain ...

Will IVF work for a particular patient? The answer may be found in her blood

... blood, an easily accessible biological sample. blood samples were taken at eight different stages ... concerned with angiogenesis (the growth of new blood vessels), endothelin signalling (blood vessel ... growth factor (signalling processes in blood vessel growth), and pyruvate metabolism (the ...

Gene expression findings a step toward better classification and treatment of juvenile arthritis

... looked for differences in the children's blood samples that corresponded with the different ... JIA. "We analyzed gene expression patterns in blood cells and found that we could indeed distinguish ... factor (RF) positive JIA, meaning their blood tested positive for an antibody commonly seen in ...

Singapore nanotechnology combats fatal brain infections

... component that enables them to pass through the blood brain barrier to the infected areas of the brain ... of IBN's peptide nanoparticles to traverse the blood brain barrier offers a superior alternative to ... safe for use because they also do not damage red blood cells. IBN Executive Director Jackie Y. Ying, ...

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells

... that placental stem cells, like umbilical cord blood and bone marrow stem cells, can be used to cure ... such as a muscle cell, a brain cell, or a red blood cell. Using stem cells from umbilical cord blood, ... diseases through their sibling donor cord blood transplantation program, which began in 1997. ...

The battle for CRTC2: How obesity increases the risk for diabetes

... switch" only flips on glucose production when blood glucose levels run low during fasting. "The ... new classes of drugs that might help to lower blood sugar by disrupting this alternative pathway," ... to the development of hyperglycemia, or high blood glucose levels. We asked whether chronic ER ...

Omega-3 fatty acids appear to impact AMD progression

... stage. We hypothesize that the rapid rise of blood glucose initiated by high-GI foods results in ... how quickly carbohydrates are broken down into blood sugar, also known as blood glucose. Foods such as sweetened drinks, sodas ...

Trans fats hinder multiple steps in blood flow regulation pathways

... fatty acids that interfere with the regulation of blood flow. A new report reveals a new way in which ... fats" gum up the cellular machinery that keeps blood moving through arteries and veins. In the ... more than one key enzyme in the regulation of blood flow. Kummerow begins by describing the two ...

Potential for non-invasive brain tumor treatment

... an ultrasound catheter that can fit into large blood vessels of the brain and perform two essential ... bloodstream, and then insert a catheter via a blood vessel to the site of the brain tumor," said Carl ... enough to be placed in one of the brain's main blood vessels that was capable of serving the dual ...

Test detects molecular marker of aging in humans

... that the same biomarker is present in human blood and is strongly correlated both with ... have solved technical hurdles to develop a simple blood test to detect p16INK4a expression, which is ... Medicine. They validated the test by obtaining blood from two groups of healthy human volunteers, ...

Chemical in blood may explain susceptibility to bladder pain

... COLUMBUS, Ohio A marker in the blood of both cats and humans that was identified in a ... studies of the chemicals that appeared in blood samples suggest that the way tryptophan, an ... microspectroscopy to tell the difference between blood samples indicating the presence or lack of ...

Major breakthrough in early detection and prevention of AMD

... (CNV) the invasive growth of new blood vessels in the thin vascular layer that provides ... Central vision loss occurs when these abnormal blood vessels invade the retina, the light-sensitive ... team was able to detect these same abnormal blood vessels in the living eyes of mice by attaching ...

From the glass to the brain in 6 minutes

... of beer or two glasses of wine, leading to a blood alcohol level of 0.05 to 0.06 percent, changes ... study were published in the Journal of Cerebral blood Flow and Metabolism . Metabolism of brain ... through a long straw. The goal was to reach a blood alcohol content of 0.05 to 0.06 percent a level ...

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions

... diabetes, and how the body becomes aware of low blood sugar. The presentations comprise four symposium ... timing medication to avoid a precipitous drop on blood sugar following workouts. The symposium will take ... of pancreatic beta cell mass in the regulation of blood sugar, and whether it is possible to modulate ...

Genetically corrected blood cells obtained from skin cells from Fanconi anemia patients

... (CIEMAT), has resulted in the generation of blood cells from skin cells of patients with a genetic ... cells) which later can be differentiated towards blood cells. These results are the proof of concept ... one of the main problems lies in the lack of blood cell in the bone marrow of those affected. ...

Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine

... consequences of inflammation. Nitric oxide in the blood is an important host defense against bacterial ... damages host tissue. A nitric oxide level in the blood of mice lacking meprin was much higher than the ... an inflammatory serum factor produced by white blood cells, and this factor is elevated in both the ...

New device detects heart disease using less than one drop of blood

... that only bind to endothelial progenitor cells. blood flows through the device through a funnel-like opening (except the blood enters through the narrow end and exits through ... with a new model to study the effects that blood flow in the body has on cell binding (like clots ...

American Chemical Society's weekly PressPac -- May 27, 2009

... show "immense potential" in prevention of blood clots ACS Nano Scientists are reporting ... other anti-platelet agents used widely to prevent blood clots in coronary artery disease, heart attack ... of platelets, disk-shaped particles in the blood that form clots. The scientists describe ...

Study shows CGM devices also benefit people with type 1 diabetes

... already been successful in achieving recommended blood sugar goals can further benefit from using ... while cutting down on the frequency of low blood sugars, called hypoglycemia. Research has shown that good blood sugar control is a key factor in reducing the ...

Old stain in a new combination

... reproduce in liver cells and then attack the red blood cells. This causes severe symptoms such as high ... body and reduce the number of gametocytes in blood by half. This makes the transmission of the ... physicians checked the number of gametocytes in blood samples three, seven, and fourteen days after the ...

Genetic factors may predict depression in heart disease patients

... health which includes the body's network of blood vessels, arteries and veins may be a predictor ... recommended by the National Heart, Lung and blood Institute (NHLBI). Researchers targeted 59 ... the cells that line the inner surface of blood vessels; and omega-3 fatty acid metabolism, which ...

Komodo even more deadly than thought: Research

... allows it to kill large animals through rapid blood loss." The researchers used computer modeling ... many snakes. The venom causes a severe loss in blood pressure by preventing blood clotting and ...

American Chemical Society's Weekly PressPac -- May 13, 2009

... the same protein known to protect human blood from radiation damage. ARTICLE #3 FOR ... Research Amid emerging concerns that blood platelets donated for transfusion by individuals ... have known that abnormal platelets in the blood of diabetics may predispose these individuals to ...

Babies born to native high-altitude mothers have decreased risk of low birth weight

... indigenous to the Andes Mountains deliver more blood and oxygen to their fetuses at high altitude than ... the uterine artery of Andean women delivered more blood and oxygen to the fetus compared to women of ... Andean heritage, the greater the uterine artery blood flow, the greater the oxygen delivery to the ...

Environmental exposures may damage DNA in as few as three days

... called methylation have been found in the blood and tissues of lung cancer patients," said ... matter induced changes in DNA methylation in blood from healthy subjects who were exposed to high ... who worked in a foundry near Milan, Italy. blood DNA samples were collected on the morning of the ...

American College of Medical Genetics affirms importance of newborn screening dried blood spots

... Importance of Residual Newborn Screening Dried blood Spots. In May 2006, ACMG recommended that all ... aspect of newborn screening is the "dried blood spot, filter card" which provides the specimen on ... in the United States. "Residual dried blood spots are vital to effective newborn screening ...

New evidence of how high glucose damages blood vessels could lead to new treatments

... glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking ... say. They found a decreased ability of blood vessels to relax resulted from increased activity ... of the powerful vasodilator nitric oxide in blood vessels, a shortfall that increases the risk of ...

Heart protein regulates blood vessel maintenance

... vascular smooth muscle cells (vSMCs), which line blood vessels. Vascular smooth muscle cells undergo a ... states is necessary for the normal development of blood vessels, regulating blood pressure, and repairing vessels that suffer from ...
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