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Biopsy in Biological News

ESHRE launches international study of polar body screening

... if a novel method of doing PGS using polar body biopsy and chromosome array analysis offers a ... status of an oocyte in at least 90% of polar body biopsy attempts." The two centres chosen for the pilot ... restricts the possibility of undertaking embryo biopsy at a later stage of development. The data from ...

Human adult testes cells can become embryonic-like

... men could be cured of disease with a biopsy of their own testes," says the study's senior ... an incurable disorder or disease could have a biopsy of their testes, which Dym says is a common ... go on to produce sperm would be removed from the biopsy tissue, and grown in the laboratory with the ...

Freezing prostate cancer does a man's body good

... the use of 3-D transperineal mapping biopsy for determining the extent of prostate cancerwhen ... Additionally, Onik presented results of a 3-D biopsy method that provides superior information on the ... Onik. According to Onik, the 3-D transperineal biopsy complements the focal cryoablation approach ...

New, noninvasive prostate cancer test beats PSA in detecting prostate cancer

... have prostate cancer that is so accurate a biopsy wont be needed to rule cancer out, Chinnaiyan ... rising PSA levels before they underwent prostate biopsy at a University of Michigan urology clinic. Among this group, biopsy results confirmed a diagnosis of prostate cancer ...

Novel technique changes lymph node biopsy, reduces radiation exposure

... gold nanocages. Their work can minimize invasive surgical lymph node biopsy procedures to determine if breast cancer has metastasized and reduce the ... A piece of tissue can then be removed using a minimally invasive needle biopsy and tested for cancer. "We will convert an invasive surgical procedure ...

Novel technique changes lymph node biopsy, reduces radiaiton exposure

... gold nanocages. Their work can minimize invasive surgical lymph node biopsy procedures to determine if breast cancer has metastasized and reduce the ... A piece of tissue can then be removed using a minimally invasive needle biopsy and tested for cancer. "We will convert an invasive surgical procedure ...

Anti-tumor therapy with endoscopic ultrasound may fight cancer more safely and effectively

... to operate within the lumen of the gut while at the same time detect, biopsy and treat lesions and tumors that lie outside the intestinal wall. This ... blood flow in blood vessels in and around tumors as well as detect and biopsy tumors and lymph nodes as small as 3-5 mm. This allows doctors to avoid ...

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

... the average risk of cancer following a diagnosis of isolated HG-PIN in biopsy ranged from 20 percent to 30 percent, the researchers say. And while other ... is equal or above 100 the possibility to find cancer in the subsequent biopsy is 90 percent, Paciucci said. Currently, the diagnosis of cancer is made ...

Trial seeks 'genetic fingerprint' for predicting drug effectiveness

... in the trial. Prior to surgery, all study participants will have a biopsy to set baseline standards for genetic testing to determine which patients ... are eligible for surgery. Those who are suitable will have another tissue biopsy after surgery. Researchers will compare pre- and post-surgery tissue ...

Cardiologists and heart surgeons meet for 'Controversies and Advances' conference

... isolated cardiac stem cells from adult human and porcine endomyocardial biopsy specimens, differentiated them in vitro and characterized their functional ... We also have developed methods to isolate and expand CSCs from routine biopsy specimens; they readily become excitable and contractile. These ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

... than 25 percent lifetime risk of breast cancer without mutations also had a documented increase in risk-reduction surgery. Women who had a biopsy after undergoing risk evaluation were twice as likely to choose a risk-reducing mastectomy. Forty percent of the women who were mutation carriers ...

Single thawed embryo transfer after PGD does not affect pregnancy rates

... genetic disorders because of concerns about how well biopsied embryos survive after freezing and thawing. "It was thought that the effect of the biopsy might reduce the embryos' tolerance to freezing. This concern was not based on any scientific evidence, only on observations of low survival rates of ...

New MRI technique could mean fewer breast biopsies in high-risk women

... a method that, applied in MRI scans of the breast, could spare some women with increased breast cancer risk the pain and stress of having to endure a biopsy of a questionable lump or lesion. The universal technology will give radiologists greater confidence in visually classifying a lesion as malignant ...

University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease

... of cancer known as esophageal adenocarcinoma. Currently, diagnosing BE depends on the skill and experience of individual pathologists examining biopsy samples from patients, often relying on subjective criteria. Identifying biomarkers that can be associated with a particular condition provides an ...

Liver disease 'shrunk' by blood-pressure drug

... scars are no longer produced or maintained, but instead shrink. Professor Mann said: "By measuring the amount of active NF-kB in the liver from a biopsy sample, we may be able to tell which patients will benefit from treatment with losartan or similar drugs such as ACE inhibitors. This may prove to be ...

As good as it gets: Octogenarian muscles don't get stronger with exercise

... muscle size. This was surprising because an earlier study had found that 70-year-old women gained 5% muscle mass with resistance training. The biopsy results confirmed the MRI results: there was no change in the size of the individual muscle strands, pre-training versus post-training. This confirms ...

Society of Interventional Radiology hosts 34th annual scientific meeting

... the cancer is and just destroy the cancer," says study author Gary M. Onik, M.D., interventional radiologist. And details about a better mapping biopsy for determining the extent of prostate cancer will be given. (Embargoed for release until Monday, March 9, 2009, 9 a.m. Eastern) VNR, B-roll and ...

Stroma genomic signature predicts resistance to anthracyclin-based chemotherapy in breast cancer

... order to measure the expression activity pattern of thousands of individual genes. Meanwhile, all patients included in the said study had a tumor biopsy prior to receiving an anthracyclin-based chemotherapy followed by surgical excision of the tumour a protocol that clinicians call neo-adjuvant ...

Children's Hospital scientists achieve repair of injured heart muscle in lab tests of stem cells

... approach is that as a therapy, it would be an autologous transplant. This means that for a patient who suffers a heart attack, we would take a muscle biopsy from his or her muscle, isolate and purify the myoendothelial cells, and re-inject them into the injured heart muscle, thereby avoiding any risk of ...

Adult stem cell breakthrough

... by these results. Just four days after transplantation the graft was almost indistinguishable from adjacent normal bronchi. After one month, a biopsy elicited local bleeding, indicating that the blood vessels had already grown back successfully". Martin Birchall, Professor of Surgery at the ...

Diabetes researcher gets $5M boost

... corneal confocal microscopy, to see the value in tracking the condition in this way." Diabetic neuropathy is currently measured by taking a skin biopsy from the foot, and running tests which could take up to three days, whereas the quick and non-invasive eye tests would see results in a matter of ...

For insulin sensitive overweight patients, 1 session of exercise improves metabolic health

... researchers measured whole-body FA oxidation [FAO] and calculated non-oxidative FA disposal as the difference between FA uptake and FAO. A muscle biopsy was performed to measure the presences of triglycerides that are involved in fat storage. The morning after the trials, the researchers observed ...

UCLA researchers locate and image prostate cancer as it spreads to lymph nodes

... approach was pioneered in the field of breast cancer with testing of the sentinel lymph node, the first place breast cancer goes when it spreads. A biopsy can determine if the cancer is in the sentinel node, therefore spreading, and oncologists base their treatment decisions on that information. In ...

Human embryonic stem cells developed from 4-cell embryo; world first may lessen ethical concerns

... of all four cells," said Dr. Van de Velde. The work could have major ramifications for preimplantation genetic diagnosis (PGD), by enabling the biopsy of one cell from a 4-cell stage embryo, allowing the remaining three cells to develop into a blastocyst (five day embryo) which could be transferred ...

Embryo biopsy does not affect early growth and risk of congenital malformations in PGD/PGS babies

... today (Tuesday): "These findings are very reassuring for the children, parents and clinicians involved in PDG/PGS treatments. They show that embryo biopsy in PGD and PGS had no adverse impact on singletons' growth or medical outcomes." PGD/PGS is an invasive procedure that involves removing cells ...

New study finds most North Pacific humpback whale populations rebounding

... as well as estimate the sizes of different populations. In addition to whale fluke photographs, SPLASH researchers collected more than 6,000 biopsy samples for studies of genetics and pollutants, along with thousands of additional photographs to determine how levels of scarring from line ...

A new analysis method allows to find out the sex of the baby from the second month of pregnancy

... determining the sex of the baby as soon as possible, would avoid the processes of invasive prenatal diagnosis such as amniocentesis, chorionic villus biopsy or cordcentesis, which involve a danger for the life of the foetus. Genetic research and molecular biology The research work has been ...

Vitamin D and calcium influence cell death in the colon, researchers find

... and reportable," Fedirko says. "We will have to fully evaluate each marker's strength as we accumulate more data." The studies of colorectal biopsy samples are part of a larger effort to identify a portfolio of measurements that together can gauge someone's risk of getting colon cancer, says ...

Long-term use of mechanical ventilation contributes to the deterioration of human diaphragm muscle

... three hours. Levine said both groups were demographically and statistically similar except for the time each had spent on mechanical ventilation. biopsy results on the other hand were different. Compared to the control group, the diaphragms of the 14 case study members revealed: 23 percent ...

Northern right whales head south to give birth, leave genetic 'fingerprints' with NOAA researchers

... Conger arrived in Florida in early January. Sampling is tightly controlled by federal authorities, and Pace and colleagues are permitted to biopsy no more than 30 whales this calving season. Samples are collected using a lightweight dart which takes a sample of skin and blubber about the ...

Bacteria that cause urinary tract infections invade bladder cells

... M.D./Ph.D. student at the School of Medicine and lead author of the paper. "And it was thought that bacteria could not penetrate that barrier." A biopsy could reveal the presence of bacteria in bladder cells, but taking a tissue sample in an infected bladder incurs an unacceptable risk of allowing ...

New X-ray technique targets terrorists and tumors

... taken to create a sample scan from hours to just a few minutes. This shorter period would eliminate the problem of radiation damage, allowing biopsy samples to be studied and normal tissue types to be distinguished from abnormal. Professor Cernik said: We have demonstrated a new prototype X-ray ...

Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients

... for more than a year and diagnosed with a neurogenic bladder that is not adequately responding to medical therapy. The urologist first performs a biopsy on the patient to retrieve the cells. The cells are then sent to Tengions manufacturing facility where they are grown in culture and then seeded onto ...

Pittsburgh scientists identify human source of stem cells with potential to repair muscle

... Department of Orthopaedic Surgery at the University of Pittsburgh School of Medicine. "To make this available as a therapy, we would take a muscle biopsy from a patient with a muscle injury or disease, remove the myoendothelial cells and treat the cells in the lab. The stem cells would then be ...

Scientists identify embryonic stem cells by appearance alone

... Meissner and Wernig successfully reprogrammed about 0.5 percent of the fibroblasts. Given that there are millions of cells in a typical skin biopsy (researchers used skin from either the end of the tail or from the ear of the mouse), that translates into thousands of stem cells, each one capable ...

60 second test could help early diagnosis of common brain diseases

... on conversations with patients, memory tests, physical examinations and, occasionally, brain scans. It is sometimes not until post-mortem or after a biopsy that cause of illness can be confirmed. ...

3-D ultrasound scanner could guide robotic surgeries

... to spot potential tumors in real time during biopsy procedures, making a diagnosis of cancer harder ... CT scans, of a patients' organs captured prior to biopsy to locate lesions suspected to be cancer. As ... coordinates into a simple robot that controlled a biopsy needle, and the robot did the rest. The ...

Carnegie Mellon develops non-invasive technique to detect transplant rejection at cellular level

... the clinic ultimately will reduce the number of biopsy procedures and should greatly improve the quality ... organ. By only sampling several small areas, a biopsy may miss the area of the transplanted organ where ... in pre-clinical or clinical research because biopsy samples are very limited in location and size." ...

War on terror meets war on cancer

... important in tumors in which obtaining a biopsy is difficult." If doctors can do a biopsy to remove a sample of a tumor, the cancer cells ... how rapidly they grow. "But if you can't biopsy it because it's in your brain or another ...
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