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Systems biology recommended as a clinical approach to cancer

... define the framework of the other approaches. biochemical networks are central to biological function, ... useful way to understand their workings. biochemical models are the ideal means to design and predict ... can be understood, an assessment of the overall biochemical network, not just the individual molecular ...

Kelvin Lee winner of Biochemical Engineering Journal Young Investigator Award

... The biochemical Engineering Journal and the ECI biochemical Engineering Conferences have announced that ... Biotechnology Institute, is the winner of the biochemical Engineering Journal Young Investigator Award. ...

Toxic molecule may help birds 'see' north and south

... it instead as an ideal reaction partner in a biochemical process involving the protein cryptochrome in a ... direction in flight, appear to alter this biochemical compass in the eye, allowing the bird to see how ... low concentrations but not too low "to make the biochemical compass work effectively," he said. Although ...

Toward a systems biology map of iron metabolism

... describing qualitative and quantitative models of biochemical reaction networks. It can also be used to express ... SBML is designed to enable the exchange of biochemical network models between different software ... For example, SBML is also understood by biochemical modeling software such as COPASI and networks ...

American Chemical Society Weekly PressPac -- April 8, 2009

... are reporting the identification of key biochemical changes that put sperm "in the mood" for ... acids within proteins. However, the specific biochemical details have been a deep mystery. Using ... samples were also reported, providing the first biochemical description of what puts sperm "in the mood." - ...

Margarita Saenz, M.D. is recipient of Genzyme/ACMGF Fellowship in Biochemical Genetics

... (ACMGF) Clinical Genetics Fellowship in biochemical Genetics at the ACMG 2009 Annual Clinical ... training of clinicians in the field of clinical biochemical genetics and especially in the diagnosis, ... following residency in a genetics fellowship on biochemical genetic diseases. "The Genzyme/ACMGF Clinical ...

Reversing ecology reveals ancient environments

... metabolism that determine the physiological and biochemical properties of cells-in great detail. But ... the metabolic network, organisms accumulate biochemical compounds from their interactions with the ... and salinity. "This gives us a way to predict the biochemical environment of organisms and learn ecology from ...

Evolution education for K-12 teachers needs beefing up, says CU-Boulder professor

... is difficulty in grasping the idea that random biochemical events can produce novel and useful adaptations, ... "We can't leave students with mysteries about how biochemical processes work, because that's when nonscientific ... to identify commonly held misconceptions of biochemical processes, he said. As part of BCI, Klymkowsky ...

Key to future medical breakthroughs is systems biology, say leading European scientists

... Simply knocking out one target molecule in a biochemical pathway is turning out to be a flawed strategy ... alternative routes to be used, the network of biochemical pathways can enable a disease to by-pass a drug. ... by disrupting two or three key intersections on a biochemical network. This could lead to significant advances ...

Biochemistry of human physiology in health and disease is focus of updated clinical text

... edition of a leading book that describes the biochemical and physiological fundamentals needed in a ... pathophysiology of a particular body system (how biochemical changes result in disease). Relevant laboratory methods are introduced to show how biochemical changes are measured and how they change during ...

Trustee makes donation to start new solar energy research center at Rensselaer

... The new center the Baruch '60 Center for biochemical Solar Energy Research will conduct unprecedented research on biochemical solar technology. Researchers at the center ... of Energy (DOE) funding for the investigation of biochemical solar power, Lakshmi is working with fellow ...

Certain anticancer agents could be harmful to patients with heart disease

... name of hedgehog antagonists interfere with a biochemical process that promotes growth in some cancer ... the researchers showed that interfering with this biochemical process in mice with heart disease led to further ... the hedgehog signaling pathway, a chain of biochemical signals that regulate cellular growth and ...

New Web resource to improve crop engineering

... feature is PlantCyc, a comprehensive plant biochemical pathway database with information from the ... The database currently contains over 500 biochemical pathways consolidated from over 290 plant ... the sequenced and annotated plant genomes in a biochemical context to facilitate the discovery of enzymes ...

UT Southwestern researchers create molecule that nudges nerve stem cells to mature

... allowed the researchers to uncover some of the biochemical steps that happen as nerve cells mature. It also ... cell begins to mature, but they don't know what biochemical pathways or genes are involved, Dr. Hsieh said. ... compound, the scientists identified a possible biochemical pathway by which stem cells begin to become nerve ...

Fruit flies show how salmonella escapes immune defenses

... "Using drosophila genetics, we found a biochemical crossroad required for both immune and apoptotic ... is able to key in on the exact site of the biochemical network and allow it to suppress both the ... suspect that other pathogens may target the same biochemical network to avoid elimination. These immune ...

Peter J. McGuire, MB BCh, is awarded the 2008-2009 Genzyme/ACMGF Clinical Genetics Fellowship

... the Genzyme/ACMGF Clinical Genetics Fellowship in biochemical Genetics at the ACMG 2008 Annual Clinical ... training of clinicians in the field of clinical biochemical genetics and especially in the diagnosis, ... following residency in a genetics fellowship on biochemical genetic diseases. The Genzyme/ACMGF Clinical ...

New insights into the diversity of Creutzfeldt-Jakob disease agents

... Kingdom and France have identified four separate biochemical subgroups in a selection of cases of ... to investigate. In this study, using two new biochemical assays, the authors identified four distinct biochemical PrPSc subgroups in 41 sCJD cases. These subgroups ...

2 genes are important key to regulating immune response

... fills in an important "missing link" in a biochemical pathway that's long been tied to disorders ... They then used sensitive assays to look for key biochemical changes occurring downstream of CD36 activation. ... apoptotic cells," Dr. Ma says. In subsequent biochemical experiments, the team identified the two genes ...

Gold nanorods shed light on new approach to fighting cancer

... of tumor cells, setting in motion a complex biochemical mechanism that leads to a tumor cell's ... team discovered, however, that a more complex biochemical scenario is responsible for killing the cells. ... but it's really caused through a complex biochemical pathway - a chemically induced process," Cheng ...

The endocannabinoids: Functional roles and therapeutic opportunities

... with the cannabinoid receptors are part of a new biochemical system in the human body, which may affect ... of cannabinoids to act through a variety of biochemical mechanisms. 2-AG also helps repair the blood ... importance in establishing the existence of a new biochemical system and its physiological roles in particular ...

Scientists track impact of DNA damage in the developing brain

... nearly every cell. In organisms both simple and complex, it serves as the biochemical blueprint for assembling and sustaining life. Diseases like cancer have ... then developed a mouse that carried an Xrcc1 gene outfitted with biochemical tags targeting the gene for inactivation by the enzyme. The result was a ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... dramatically. Advances in brain imaging, the mapping of the brains biochemical circuitry and breakthroughs in molecular genetics have significantly ... has been of central importance in establishing the existence of a new biochemical system involved in the protective reaction to a long list of neurological ...

Plant protein 'doorkeepers' block invading microbes, study finds

... research plant Arabidopsis that appear to play important roles in the biochemical mechanisms that enable plants to recognize and block out invading ... identified in this study were found to be intricately involved with the biochemical processes that enable the plant to recognize and block out invading ...

MS study offers theory for why repair of brain's wiring fails

... and in human tissue, showed that repair of nerve fibers is hampered by biochemical signals that inhibit the development of cells known as oligodendrocytes, ... where repair attempts were under way. Tcf4 is involved in a cascade of biochemical events known as the Wnt (pronounced "wint") pathway, whose importance has ...

Plant protein 'doorkeepers' block invading microbes, study finds

... research plant Arabidopsis that appear to play important roles in the biochemical mechanisms that enable plants to recognize and block out invading ... identified in this study were found to be intricately involved with the biochemical processes that enable the plant to recognize and block out invading ...

American Chemical Society's Weekly Presspac -- June 17, 2009

... Gordon says. "We propose ways of harvesting oil from diatoms, using biochemical engineering and also a new solar panel approach that utilizes genetically ... ARTICLE #2 FOR IMMEDIATE RELEASE "Milking Diatoms for Sustainable Energy: biochemical Engineering Versus Gasoline-Secreting Diatom Solar Panels" DOWNLOAD ...

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

... as a model study organism for investigation of nitrogen fixation and other biochemical processes. It will also pave the way for new applications in ... the bacterium. " A. vinelandii is an attractive model organism for biochemical studies because of its ability to produce high yields of quality enzymes," ...

Sihoun Hahn, M.D., Ph.D., FACMG is the 2009-2010 Luminex/ACMGF Award recipient

... advisory committee for the Wilson Disease Association. He is Director, biochemical Genetics Program and Professor, Department of Pediatrics, Division of ... Medicine at the University of Washington School of Medicine and Director, biochemical and Molecular Genetics Laboratory, Seattle Children's Hospital. ...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

... of these small RNAs to the way they are produced within the leaf a biochemical process involving several complicated steps. The small ta-siRNAs are ... Timmermans and her team have also shown that the location of the various biochemical ingredients required for small RNA activity can impact pattern formation. ...

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

... of these small RNAs to the way they are produced within the leaf a biochemical process involving several complicated steps. The small ta-siRNAs are ... Timmermans and her team have also shown that the location of the various biochemical ingredients required for small RNA activity can impact pattern formation. ...

Scientists discover why teeth form in a single row

... While the study was in mice, past studies have shown that the involved biochemical players are active in humans as well. "This finding was exciting ... researchers said. Thanks to the work of Jiang and others, some of the biochemical pathways involved in cleft lip/cleft palate development are now ...

Duke software dramatically speeds enzyme design

... used the latest version of the algorithm to redesign the first step in the biochemical assembly line needed to make the antibiotic. "Redesigning that first ... graduate students, confirmed the algorithm's predicted designs in Donald's biochemical wet lab, using bacteria to synthesize some "quite big and tricky ...

Rot's unique wood degrading machinery to be harnessed for better biofuels production

... (FPL) have translated the genetic code that explains the complex biochemical machinery making brown-rot fungi uniquely destructive to wood. The same ... removing the lignin. Up until this study, the underlying genetics and biochemical mechanisms were poorly understood. DNA sequence is the first step in ...

Here's venom in your eye: Spitting cobras hit their mark

... eyes of potential attackers. A new study published in Physiological and biochemical Zoology reveals how these snakes maximize their chances of hitting the ... be in the ballpark. The paper appears in an issue of Physiological and biochemical Zoology on the focused topic "Functional Consequences of Extreme ...

When it comes to sleep research, fruit flies and people make unlikely bedfellows

... Price and his colleagues made this discovery using a combination of biochemical and genetic approaches. For the biochemical approaches, normal and mutated versions of the fruit fly's ...

Nearly a century later, new findings support Warburg theory of cancer

... theory on the origin of cancer earned him the Nobel Prize in 1931, but the biochemical basis for his theory remained elusive. His theory that cancer starts ... of glucose, a process called glycolysis. Indeed, glycolysis is the biochemical hallmark of most, if not all, types of cancers. Because of this difference ...

Researchers first to 'see' reactive oxygen species in vital enzyme

... or vitamin B2. These proteins are now known to catalyze a wide range of biochemical reactions, including those that use molecular oxygen (O2) to help convert ... a molecular complex that often forms halfway through important biochemical reactions. These intermediates possess high chemical potential energy, ...

Shared survival mechanism explains why 'good' nerve cells last and 'bad' cancer cells flourish

... and cancer cells achieve the common goal of inhibiting the series of biochemical events called apoptosis that eventually causes cells to break down and ... or series of chemical reactions. This pathway the pentose phosphate biochemical pathway inhibits the activation of a key protein involved in the process ...

A scientific breakthrough on the control of the bad cholesterol

... A study performed by the team of Dr. Nabil G. Seidah, Director of the biochemical Neuroendocrinology Research Unit at the IRCM, shows for the very first ... risks of developing cardiovascular diseases. "By performing a series of biochemical experiments, we discovered that annexin A2 binds strongly to PCSK9 and ...

UI researchers help to improve carbon measurements in global climate studies

... the atmosphere, according to Greg Carmichael, professor of chemical and biochemical engineering in the UI College of Engineering and co-director of the Center ... co-director; and Charles Stanier, assistant professor of chemical and biochemical engineering, and assistant research engineer at IIHR-Hydroscience and ...
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