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Autopsy in Biological News

Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

... were collected through the Simmons Center's warm autopsy program, which is the only one for lungs in the ... after death. In response, she developed the warm autopsy program. "The tissue has to be collected ... cells degrade very quickly, so without the warm autopsy protocol, we couldn't have done the activity ...

Brain malformations significantly associated with preterm birth, Wake Forest research shows

... For his study, Brown looked at 1,168 autopsy files that contained congenital brain defects as ... In his review, Brown found that, in the autopsy cases with brain defects, the mean gestational ... to 21.5 percent of those with defects. In the autopsy cases with brain defects, the rate of preterm ...

Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives

... When an individual aged 1-50 years dies suddenly, autopsy reveals an inheritable heart disease in the majority of the victims. But in approximately 20% autopsy does not reveal the cause of death. "We thought ... an SUD and where either there had been no autopsy (53.8%), or ...

1/3 of risk for dementia attributable to small vessel disease, autopsy study shows

... be what most people fear as they grow older, but autopsy data from a long-range study of 3,400 men and ... both conventional wisdom and from those of most autopsy studies of brain aging and dementia, says Dr. ... of the broad reach of the population on which the autopsy study was based, says Dr. Montine. Most studies ...

Abnormal brain circuits may prevent movement disorder

... for dystonia patients. There are half a million people in the United States alone. The brains of people with inherited dystonia are normal at autopsy and the exact cause of their movement abnormality is unknown. David Eidelberg, MD, the senior author of the study published in the Journal of ...

Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies

... Mark Burns, PhD, an assistant professor at GUMC. "No one knows why it occurs, but abnormal amounts of amyloid plaque have been found during an autopsy in about a third of brain injury victims, some of whom were children who would ordinarily never have had these deposits," says Burns. "Remarkably, ...

'Virtual autopsy' helps identify drowning as cause of death

... Radiology. MDCT is comparable to conventional autopsy in demonstrating airway froth and sediment that ... to facilitate or reduce the need for conventional autopsy when drowning is the suspected cause of death," ... may be a secondary rather than primary event. autopsy findings that support the diagnosis of drowning ...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

... European power had he escaped his exile. An autopsy at the time cited stomach cancer as the cause of ... combined current medical knowledge and autopsy reports, memoirs of the physicians who treated ... and medical histories of family members. autopsy and physician descriptions revealed no telltale ...

Study finds mix of disease processes at work in brains of most people with dementia

... to donate their brains upon death. The current study compared clinical and autopsy data on the first 141 participants who have died. Annual physical and ... traumatic brain injury or others. Comparison of the clinical and autopsy results showed that only 30 percent of people with signs of dementia had ...

New research shows that flu is a trigger of heart attacks

... deaths between 1993 and 2000 in St Petersburg that had been shown by autopsy reports to be due to coronary heart disease. "This was a population ... in the absence of these medicines," said Prof Madjid. "Relying on autopsy reports rather than death certificates enabled us to be much more accurate ...

A potential biological cause for sudden infant death syndrome

... New autopsy data provide the strongest evidence yet that sudden infant death syndrome ... at Children's Hospital Boston and Harvard Medical School examined brain autopsy specimens from 31 infants who had died from SIDS and 10 who had died ...

Study offers window into human behavior, brain disease

... is currently trying to study von Economo neuron-rich regions in living patients using neuroimaging. They also are studying VENs, themselves, in autopsy studies using neuropathological techniques. As FTD is a disease for which there is as yet no disease-modifying therapy, studies of von Economo ...

Scientists work to identify genes that contribute to early heart attack risk

... Study of Atherosclerosis (MESA). Using DNA data from the PDAY study, the scientists will work to pinpoint specific atherosclerosis genes. This autopsy study included about 3,000 young people, ages 15 to 34, who died from accidental causes, suicide and homicide. This study, which started in 1985, ...

Mouse study reveals new clues about virulence of 1918 influenza virus

... those with compromised immune function, the 1918 flu disproportionately killed young people in the prime of life. Modern analyses of 1918 flu victim autopsy samples show extreme and extensive damage to lung tissues. This observation gave rise to the hypothesis that the 1918 flu virus infection provoked an ...

Alzheimer's found to be mostly genetic

... cases of dementia, of which Alzheimer's is the most common form, received complete, in-home clinical diagnostic evaluations by a doctor and nurse. autopsy confirmation of diagnoses is being collected. The research for this study was supported by grants from the National Institute on Aging and the ...

Argonne researchers confirm lead in Beethoven's illness

... a change of personality and abdominal illness in his late teens and early 20s that persisted throughout his adult life. His abdominal symptoms and autopsy findings are both consistent with lead poisoning, Walsh said. There have been documented cases of deafness resulting from lead poisoning, but this ...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

... group created a live virus with all eight of the Spanish flu viral genes. The genome sequence information was recovered in fragments from lung autopsy materials and lung tissues from a flu victim who was buried in the Alaskan permafrost in 1918. The virus is contained at the Centers for Disease ...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

... study) to try to determine which vascular or genetic factors contribute to the syndrome. They will also attempt to replicate their MRI data in an autopsy study of patients who died with dolichoectasia. ### Article: "Intracranial Arterial Dolichoectasia and Small-Vessel Disease in Stroke ...

Neuronal 'traffic jam' marks early Alzheimer's disease

... and sac-like vesicles that are the cargo-carriers for cellular proteins. Goldstein and his colleagues also examined brain sections taken at autopsy from humans with different stages of Alzheimer's disease. They detected the same kinds of swelling in those samples that they had seen in the mice. ...
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