Aortic in Biological News

Single gene defect can cause stroke, other artery diseases

... a single gene defect that causes thoracic aortic aneurysms and dissections as well as early onset ... Stroke and Moyamoya Disease, Along with Thoracic aortic Aneurysms and Dissections," was published early ... than 60 years in women. Premature thoracic aortic aneurysms and dissections were the main vascular ...

Interventional treatment can be recommended as first-line treatment for 'silent killer'

... that uses stent grafts to treat abdominal aortic aneurysms (AAA), has low re-intervention rates ... into the femoral artery and directed to the aortic aneurysm. The doctor passes a stent graft, which ... direct pressure from being exerted on the weak aortic wall, explained Sabharwal. Interventional ...

Stent grafts: a better way to treat blunt trauma injuries

... a complication of surgical repair for thoracic aortic aneurysms. "Analysis of the available data ... of choice for repair of the most common traumatic aortic injury," said Eric K. Hoffer, the director of ... he added. Injuries causing thoracic (chest) aortic trauma are life-threatening, often resulting in ...

'Healthy' sterols may pose health risk

... in heart valves and lead to stenosis. aortic valve stenosis (AS) results from cholesterol ... whether plant sterols can also accumulate in aortic valves. They collected blood samples from 82 patients with severe AS and aortic valves from 21 individuals undergoing valve ...

Life-threatening gene defect located by UT-Houston researchers

... in people who suffer from hereditary thoracic aortic disease, which can kill victims with little warning in the prime of their lives. Thoracic aortic disease, specifically thoracic aortic aneurysms leading ...

Society of Interventional Radiology hosts 34th annual scientific meeting

... for release until Tuesday, March 10, 2009, 9 a.m. Eastern) Abdominal aortic Aneurysm Recommending Treatment for "Silent Killer" Abdominal aortic aneurysms can be treated successfully by a minimally invasive procedure ...

Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo

... of 560 nanometers, to detect reactive oxygen species production in the aortic smooth muscle cells of rats. They incubated the cells with hydro-Cy3 and ... lipopolysaccharide endotoxin (LPS), an inflammatory molecule that binds to aortic cells and causes reactive oxygen species to be produced, or the control ...

Cardiologists and heart surgeons meet for 'Controversies and Advances' conference

... The ongoing debate as to whether it is better to replace and repair aortic and mitral valves surgically or to manage them medically is just one ... new techniques. Fridays sessions look at coronary artery disease (part 2), aortic valve disease, congenital heart disease, and surgery and interventional ...

Register now for the Society of Interventional Radiology's 34th Annual Scientific Meeting

... AV fistulas and dialysis Seeing the promise of drug-eluting stents: critical limb ischemia Recommending treatment for "Silent Killer": abdominal aortic aneurysm Visit www.SIRmeeting.org to register online (free), view scientific abstracts and download a meeting schedule. Please contact SIR's ...

Hypertension develops early, silently, in African-American men

... body mass index, body fat, blood lipids and glucose levels. The researchers measured vascular function in a variety of ways, including: aortic blood pressure and stiffness brachial blood pressure carotid artery blood pressure carotid artery thickness and stiffness They found the ...

NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves

... professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs). aortic valves taken from pigs are used in thousands of human heart valve replacement surgeries annually, but they have a high rate of failure due to ...

At risk for peripheral arterial disease? Simple quiz provides key so you can circulate better

... tests are needed. More than 322,000 people have been screened to date, with one in four at risk for PAD. Select sites will also screen for abdominal aortic aneurysm, stroke and venous disease. While more than 50 percent of PAD patients may not show signs of the disease, screening is essential for ...

Long-term study of middle-aged mice shows

... The resveratrol treated mice also had improved markers for cardiovascular health. Their arteries were more youthful, and they had reduced aortic stiffness. They also had fewer free radicals and DNA damage. "Frailty in humans is an important health concern," says Christoph Westphal, M.D., ...

Mutant gene identified as villain in hardening of the arteries

... in Cell Metabolism. The researchers found that mice engineered without the Akt1 gene and fed a high cholesterol diet had many more signs of aortic atherosclerosis compared to their littermates. And, surprisingly, their coronary lesions were similar to humans, say the scientists. About 20 ...

Vitamin E trials 'fatally flawed'

... In lab, animal or human studies, theres evidence that vitamin E can reduce oxidative stress, inhibit formation of atherosclerotic lesions, slow aortic thickening, lower inflammation, and reduce platelet adhesion. Some human studies using lower levels of vitamin E supplements, such as 100 to 400 I.U. ...

Percutaneous aortic valve replacement safe, successful in high-risk patients

... aiding in the replacement of narrowed, calcified aortic valves in patients too sick to withstand ... experienced improvements in both the size of the aortic valve and in the severity of heart failure. To ... 17 elderly patients with a severely narrowed aortic valve, all of whom had been turned down for ...

Bone and cartilage growth to blame for heart valve disease

... certain cells to reprogram into bone cells in the aortic valve and cartilage cells in the mitral valve, ... of Medicine, who examined diseased mitral and aortic valves removed during surgery for the study. ... is a major culprit in strokes and heart failure. aortic valve disease can lead to heart failure, ...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

... with dolichoectasia are more likely to have aortic aneurysms, a potentially fatal weakening of the ... French researchers who linked dolichoectasia with aortic aneurysm reveal new evidence that links the ... you should look for an associated abdominal aortic aneurysm and carefully search for associated ...

Cellular message movement captured on video

... These time-lapse images of a bovine aortic endothelial cell reveal the motion toward the cell's nucleus of a ... proteins tagged with red and green fluorescence markers to the bovine aortic endothelial cells, grew them in tissue culture, and filmed them while they ...

New GI technologies improve internal organ visualization

... Using EUS to guide them, researchers punctured the myocardium and aortic valve or coronary artery in the six pigs; three received angiography and three received thermal ablation, or clearing of the aortic valve. The repeat puncture of the cardiac walls and injection of contrast ...

Cincinnati surgeons report new treatment for often-fatal injury

... a new, minimally invasive method for repairing a common and deadly form of aortic injury--an advance that could help reduce the number of deaths caused by ... 90 percent of the patients who suffer this injury--known as blunt thoracic aortic trauma--die before ever reaching a hospital. The aorta is the main ...

Why do aneurysms form? New studies suggest leading role for white blood cells

... out. But despite the deadly toll of this condition, called abdominal aortic aneurysm or AAA ("triple A"), experts know very little about why it ... an estimated 10 percent of all men over the age of 70 may have intact aortic aneurysms, which cause few symptoms except for occasional back pain or ...

Human stem cell treatment restores motor function in paralyzed rats

... Paraplegia from spinal cord ischemia is a serious complication that occurs in 20 to 40 percent of patients undergoing a surgical process called aortic cross-clamping. When the surgeon works on the aorta, a major blood vessel, to correct a potentially lethal aneurysm, blood flow from the heart ...

How blood flow dictates gene expression

... mouse embryo mirrors events in previous tissue-culture studies. They found that Klf2 is expressed on the high-flow side of developing mitral and aortic valves in the heart of a 14-day-old embryo. The researchers surmise that the mechanical stimulus of blood flowing in a vessel leads to the ...

Minorities, uninsured less likely to receive care at high-volume hospitals

... from California's Office of Statewide Health Planning and Development patient discharge database. The procedures included elective abdominal aortic aneurysm repair, coronary artery bypass grafting, carotid endarterectomy, esophageal cancer resection, hip fracture repair, lung cancer resection, ...

Researchers show how air pollution can cause heart disease

... become less elastic. To measure tension in the arteries, the researchers tested how the neurotransmitters serotonin and acetylcholine affected the aortic arches of PM2.5-exposed mice differently than those of controls. The arteries taken from exposed mice were less elastic than the control group, ...