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Anthrax in Biological News

Bioterrorism and disaster preparedness explored in special issue of Medical Decision Making

... Medical Decision Making , a large-scale, covert anthrax attack on a large city would overwhelm hospital ... "Predicting Hospital Surge after a Large-Scale anthrax Attack: A Model-Based Analysis of CDC's Cities ... response to large-scale, covert aerosol anthrax releases in a major city, even with highly ...

Early detection and quick response are key to defense against anthrax attack

... attack on a major metropolitan area with airborne anthrax could affect more than a million people, ... in up to 6.5 percent more hospitalizations. anthrax attack scenarios typically involve the release of one kilogram of weaponized anthrax from a small airplane flying over a major city. ...

Data published in the New England Journal of Medicine support use of raxibacumab (ABthrax) for the treatment of inhalation anthrax

... in the event of life-threatening inhalation anthrax disease. "The results published today showed ... highly effective as a treatment for inhalation anthrax in both rabbits and monkeys," said Sally D. ... caused by exposure to a dose of aerosolized anthrax spores that was approximately 200 times the ...

Novel handheld device detects anthrax with outstanding accuracy and reliability

... detection device in discriminating between anthrax spores and similar-looking hoax substances. The ... Ceeker scanner accurately identified 100% of the anthrax samples used and was correct in 95% of tests ... outstanding results in distinguishing between anthrax and look-alike hoax substances, and now we have ...

Scientists present 'moving' theory behind bacterial decision-making

... bacterial protein responsible for producing anthrax toxins. One of the transition-state regulators ... of all three of these toxins is necessary to make anthrax lethal. Cavanagh and Bobay say that knowledge ... would knock out its function. That would prevent anthrax from "going lethal." "We now know more about ...

American Chemical Society's Weekly PressPac -- July 9, 2008

... New "scrubber" speeds removal of powerful anthrax clean-up agent Organic Process Research & ... to sterilize buildings and equipment following anthrax attacks. Their chemical "scrubber" removes 99 ... and could pave the way for its broader use in anthrax clean-up efforts, the scientists say. Their study ...

NIST, Army researchers pave the way for anthrax spore standards

... to assess the concentration and viability of anthrax spores after prolonged storage. The techniques ... in developing a reliable reference standard for anthrax detection and decontamination. Bacillus ... (DHS) has been working with NIST to develop anthrax spore reference materials. These materials could ...

New decontamination system kills anthrax rapidly without lingering effects

... In October 2001, letters containing anthrax spores were mailed to several news media offices ... light simultaneously, the researchers can kill anthrax spores in two to three hours without any lingering effects. The system also has the ability to kill anthrax spores hidden in places like computer keyboards ...

Anthrax cellular entry point uncovered

... The long-sought-after biological gateway that anthrax uses to enter healthy cells has been uncovered by ... the University of Alabama at Birmingham (UAB). anthrax spores enter the cell through something called ... Previous studies have shown what happens after anthrax spores enter the body and wreak havoc. ...

Team IDs weakness in anthrax bacteria

... have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new ... launched by cells infected with the bacterium. anthrax bacteria that cannot produce NO succumb to the ... of the National Academy of Sciences anthrax occurs naturally around the world and can infect ...

Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins

... proteins, including dangerous proteins such as anthrax toxin, and render them harmless using nothing but ... this method by successfully deactivating anthrax toxin and other proteins. By attaching ... recognize a protein of interest in this case anthrax toxin from a mixture of different proteins, Kane ...

American Chemical Society's Weekly PressPac -- Oct. 31, 2007

... Chemistry Amid continuing concerns that anthrax might be used as a bioterrorism weapon, ... for detecting the deadly toxins produced by the anthrax bacterium, Bacillus anthracis. The test produces ... journal. Standard identification of anthrax (Bacillus anthracis) infection relies on a ...

Northwestern to expose most deadly infectious diseases in 3-D

... real. The eerie "creature" is from the deadly anthrax bacteria -- specifically one of its proteins. ... to disable it or vaccines to prevent it. anthrax is just the beginning. The Feinberg School is ... chemical equivalent of a monkey wrench into the anthrax cell -- and others --Anderson will be mapping key ...

American Society for Microbiology honors James W. Snyder

... in bioterrorism preparedness which began several years before the 2001 anthrax attacks. He authored the ASM Cumitech publication, "Laboratory Safety, ... are the standards for the other professional groups in the LRN. The 2001 anthrax attack was diagnosed by a clinical laboratory using the techniques ...

ASM biodefense and emerging diseases research meeting

... of Concern? " OF NOTE: A plenary session on the science behind the anthrax letter attack investigation will take place on the morning of Tuesday, ... as a forum for scientists directly involved in the investigation of the anthrax letter attacks of 2001 to present their analyses and conclusions. ...

FBI unveils science of anthrax investigation

... In fall of 2001, the FBI considered how to best investigate the anthrax letters. The agency convened two blue ribbon exploratory panels, and ... members of research teams who'd been asked to examine other aspects of the anthrax case. The FBI was pleased with Sandia's work, says Michael. ...

Scripps research scientists identify blood component that turns bacteria virulent

... that the best medium for toxin production was one that people believed mimicked conditions found in the blood of a human or animal host, where anthrax bacteria would find both carbon dioxide and bicarbonate. But we've never known which of these two molecules was the more important for bacterial ...

New 'chemical radar' among national security innovations in ACS podcast

... National Institutes of Health calls Category A agents. Those materials include biological agents such as botulism toxin and infectious agents such as anthrax and smallpox. Global Challenges recalls the introduction of radar, which gave 20th century society its first method for early detection of ...

Nano vaccine for hepatitis B shows promise for third world

... bulb," he says. Baker's team has published earlier studies affirming the promise of nasal nanoemulsions as a strategy for smallpox, influenza, anthrax and HIV vaccines. The nanoemulsion technology is patented by U-M and licensed to Ann Arbor-based NanoBio Corporation. Baker is a founder and equity ...

Francisella tularensis: Stopping a biological weapon

... by inhalation, Francisella tularensis has been designated a potential biological weapon. Since the events of September 2001 and the subsequent anthrax attacks on the USA, concern about the potential misuse of dangerous pathogens including F. tularensis has increased. As a result, more funding has ...

New strategies against bird flu

... from deceased humans and animals. Victims of bird flu and SARS were examined in Hongkong, and the US-army provided samples from animals infected with anthrax and lung plague. Common to all ARDS samples was the massive amount of oxidation products found within the cells. Based on these findings, the ...

Protein data bank archives 50,000th molecule structure

... and function, including: Insulin, the protein deficient in diabetic patients p53 tumor suppressor, a protein often implicated in cancer anthrax toxin, the disease-causing protein made by anthrax Amyloid peptide, a protein implicated in Alzheimers disease. ...

'Smart' holograms help patients help themselves

... to check their blood-sugar levels; by patients with kidney disorders to check on adrenaline levels; by security forces to detect chemicals like anthrax after a terrorist attack; or, less urgently but with wide applicability, by glazing firms to detect whether water has crept in between window panes, ...

Louisiana Tech researchers investigate tracking, sensors to assist Air Force

... The technology will be considered for future improvised explosive devices detection methods, but is also applicable to civilian application such as anthrax detection in indoor environments and others. ...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

... researchers have revealed how the inhaled form of anthrax paralyzes the body's defenses and prevents immune cells from reaching the site of infection. anthrax killed five people in 2001 when letters ... EMBO Journal, may lead to quicker diagnoses for anthrax victims. The disease causes flu-like ...

Anthrax attack posed greater potential threat than thought

... new study shows that more people were at risk of anthrax infection in the Oct. 2001 attack on U.S. Sen. ... who were nearby when the letter containing the anthrax spores was opened; 20 who were outside the ... response to high-level, naturally occurring anthrax exposure in humans, and may be the first to ...

New finding points way to foiling anthrax's tricks

... Berkeley, chemists have discovered a trick that anthrax bacteria use to make an end run around the body's ... at Lawrence Berkeley National Laboratory. anthrax bacteria are known to produce two small molecules ... has been an enigma. The new study shows why anthrax bacteria require two siderophores working by two ...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

... anthrax vaccine administered in combination with a short ... implications for public health management of anthrax bioterrorism events. anthrax is caused by the spore-forming bacterium Bacillus ...

Encoded metallic nanowires reveal bioweapons

... harmless model substances to stand in for anthrax spores, smallpox virus, and protein toxins such ... test for all of these is desired, the anthrax antibody would be attached to stripe pattern 1, ... fluoresce, for example, then the sample contains anthrax spores. One particular advantage of nanowires ...

Combating anthrax: Results of study published this month as researchers look for a better vaccine

... be an alternative to the presently available anthrax vaccine. This new type of anthrax vaccine produced the immune response doctors were ... need a better vaccine to help protect people from anthrax infection, whether the vaccine is given before or ...

Newly discovered protein kills anthrax bacteria by exploding their cell walls

... a newly discovered protein could be used to fight anthrax infections and even decontaminate areas in which anthrax spores have been released. "Anthrax is the most ... and be used as a large-scale decontaminant of anthrax spores." ...

Anthrax inhibitor counteracts toxin, may lead to new therapeutics

... that successfully counteracts and inhibits anthrax toxin in animal and laboratory experiments. The novel approach used to neutralize anthrax toxin could be applied in designing potent ... and toxins, according to the researchers. anthrax toxin, secreted by ...

Anthrax spores may survive water treatment

... anthrax spores may survive traditional drinking water ... methods in the unlikely event of the release of anthrax in the water supply. Researchers report their ... of this study was to determine the fate of anthrax spores in a drinking water system that uses ...

Scientists design potent anthrax toxin inhibitor

... (NIH), have engineered a powerful inhibitor of anthrax toxin that worked well in small-scale animal tests. "This novel approach to the design of anthrax antitoxin is an important advance, not only for the value it may have in anthrax treatment, but also because this technique could ...

Driver of anthrax toxicity could lead to late-stage therapy

... Cell reports the discovery of a gene that drives anthrax bacteria's toxic effects. The gene could offer a ... might have the potential to protect against anthrax during the late stages of the disease, after ... protein (LRP6) become resistant to anthrax toxin. Furthermore, antibodies against LRP6 ...

UCSD study finds anthrax toxins also harmful to fruit flies

... Deadly and damaging toxins that allow anthrax to cause disease and death in mammals have ... activities and physiological effects of anthrax toxins. Learning how these toxins attack ... of the study, tracked the ways that two active anthrax toxins, known as lethal factor, or LF, and edema ...

Effective, safe anthrax vaccine can be grown in tobacco plants

... Enough anthrax vaccine to inoculate everyone in the United ... of tobacco plants survived lethal doses of anthrax administered later by National Institutes of ... the vaccine into mice to immunize them against anthrax and sent the mice to NIH labs, where they ...

Anthrax stops body from fighting back, study shows

... have uncovered how the inhaled form of anthrax disarms bacteria-fighting white blood cells ... most victims within days. The lethal toxin in anthrax paralyzes neutrophils, the white blood cells that ... 60 percent, paralyzing themand allowing the anthrax to move freely in the body, according to research ...

New antibody shows promise as cure for anthrax

... A new anthrax antibody engineered by scientists at The ... at Austin protects and defends against inhalation anthrax without the use of antibiotics and other more ... antibodies. The high-affinity antibody, an anthrax antitoxin, successfully eliminated ...
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