Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding
... of the unusual form of the gene, the so-called M allele
that other researchers had suspected might be ... student at OSU.
Although the presence of the M allele
has been definitively correlated with the ability ... animals. The change in the DNA sequence of the M allele
does not change the amino acid sequence of the ...
UBC researchers find first-ever 'wanderlust gene' in tiny bony fish
"Contrary to our assumption, the low-armour allele
is not linked to a preference for fresh water, or ... we found a strong association between having the allele
and the fish's inclination to move into different ... traits could explain why the low-armour allele
keeps turning up during marine sticklebacks' ...
Native Americans descended from a single ancestral group, DNA study confirms
... (western) side of the Bering Strait. Yet this allele
was absent in all 54 of the Eurasian, African and ... 908 people who were in the 44 groups in which the allele
was found, more than one out of three had the ... explanation for the distribution of the 9-repeat allele
was that all modern Native Americans, ...
Study reveals specific gene in adolescent men with delinquent peers
... primarily for those who had both the 10-repeat allele
and a high-risk family environment (one marked by ... correlation."
"Perhaps the 10-repeat allele
is triggered by constant stress or the general ... he said. "Or it's possible that the 10-repeat allele
increases an adolescent boy's attraction to ...
Gene associated with pair-bonding in animals has similar effects in human males
The researchers found that the "334" allele
of a common AVPR1A variation, the human version ... five years of more who have one or two copies of allele
334 appear to be less bonded to their partners ... female partners of men with one or two copies of allele
334 reported less affection, consensus and ...
'Armored' fish study helps strengthen Darwin's natural selection theory
... than one per cent of marine sticklebacks, this allele
is very common in freshwater populations.
... sticklebacks with the rare armour reduction allele
to freshwater experimental ponds.
"By ... a significant increase in the frequency of this allele
in their offspring, evidence that natural ...
Genes may make some people more prone to anxiety
People carrying two copies of the Met158 allele
of the COMT gene showed a significantly stronger ... than did carriers of either two copies of Val158 allele
or one copy of each. The two-Met carriers also ... The authors speculated that the Met158 allele
may raise levels of circulating dopamine in the ...
... pigmentation. If a plant with the paramutagenic allele
is crossed with a wild-type allele, the progeny get both alleles. However, the paramutagenic allele
silences the wild-type allele
and produces a plant with stippled rather than ...
Known genetic risk for Alzheimer's in whites also places blacks at risk
... Sawyer have found that the gene APOE epsilon 4 allele
is a risk factor for African-Americans as well as ... failed to detect the effect of the APOE epsilon 4 allele
on cognitive decline among blacks.
In ... the father. Having at least one APOE epsilon 4 allele
is a risk factor for Alzheimer's, but not ...
New method developed to identify genetic determinants of Alzheimer's disease
... Many studies indicate that people who have the E4 allele
are at greater risk to develop Alzheimer's disease than those with the E3 allele
and that the E2 allele
may even help resist Alzheimer's disease. As a ...
Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer
... genotypes could be a CC, GC or GG genotype. The G allele
is the most common, while the CC genotype is ... and we call people with these genotypes C allele
Our results demonstrated that C allele
carriers had a nearly two-fold (1.8) increased ...
The evolutionary foundation of genomic imprinting in lower vertebrates
... mammalian imprinting gene DMR, the unmethylated DMR of maternal allele
could not resist methylation reprogramming and started de novo methylation at the cleavage stage, while the paternal Igf2 allele
appeared to maintain its paternal methylation imprints during ...
Researchers take first look at the genetic dynamics of inbreeding depression
... conferring all of its qualities to the offspring. The other, silenced allele
is called "recessive."
Some alleles are detrimental to health. Most of ... of parental alleles in their offspring can be quite complex. Sometimes an allele
causes a disease or disorder even if it is paired with a different allele. ...
Mayo: Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's
... the odds ratio for two copies of the well-established, high-risk APOE 4 allele
was 11.5 in the subjects assembled by the Mayo group, and it was 4.8 for ... says. APOE 4 is the highest-risk Alzheimer's disease susceptibility allele
found to date. The association for women with one copy of the PCDH11X ...
New journal shows half-broken gene is enough to cause cancer
... Central's new open access journal PathoGenetics reveals that only one allele
of SMAD4 has to be damaged to put a person at risk of pancreatic and ... pancreatic and colorectal cancer. They found that having one mutated SMAD4 allele
was associated with the development of gastrointestinal polyps. This ...
International TGen-led team finds link between brain protein and Alzheimer's disease
... the most powerful genetic indicator for Alzheimer's -- the epsilon 4 allele
of apolipoprotein E. In the current study, the effects of this allele
were controlled for, yet similar observations were made. This suggests ...
Viral recombination another way HIV fools the immune system
... the effectiveness of the CTL response varies depending on which version or allele
of an immune system molecule called HLA Class I an individual has ... research participant known to have a powerfully protective Class I allele
called HLA-B27 began to experience rapid increases in viral levels much ...
Sociological research shows combined impact of genetics, social factors on delinquency
... interaction between repeating a school grade and the MAOA*2 repeat (2R) allele
in adolescent boys. For those who did not have the 2R allele, repeating a ... correlated with serious delinquency, but for those who had this 2R allele
and who repeated a grade, the propensity for serious delinquency increased ...
Did the gene for ADHD help our nomadic ancestors?
... men, who had the variant gene.
They found that those with the 7R allele
in the nomadic population were better nourished than their non-nomadic ... a sedentary lifestyle and aging.
"This suggests that this particular allele
may be beneficial in a traditional setting with high levels of habitual ...
Team finds an economical way to boost the vitamin A content of maize
... the plant. This mutant is transcribed in lower quantities than the normal allele
and steers the biochemistry toward producing higher levels of vitamin A ... can now inexpensively screen different maize varieties for this allele
and breed those that contain it to boost the nutritional quality of the ...
Gene variation may elevate risk of liver tumor in patients with cirrhosis
... lines showed that messenger RNA transcribed from DNA strands with the G allele
was more stable that that transcribed from the A version, which could ... consisted of Caucasian patients, in the MGH group, it was noted that the G allele
was more common among Asian patients; and it is well known that more than ...
A new explanation for evolutionary changes in genetic sex-determination systems
... Natural selection produces an association between the two genes an allele
that is most beneficial in males will occur most often with the allele
of the other gene that makes the individual male. It is then possible ...
deCODE discovers cause of major subtype of glaucoma
... included on the chip led to the identification of the two risk variants allele
G of rs1048661 and allele
G of rs3825942 strongly linked to XFG in Icelandic and Swedish ...
Hush little baby... Linking genes, brain and behavior in children
... of the DRD4 gene may act as a moderator of children's temperament. The authors note that the "results suggest that it is possible that the DRD4 long allele
plays different roles (for better and for worse) in child temperament" depending on internal conditions (the environment inside their bodies) and ...
New therapeutic strategy could target toxic protein in most patients with Huntington's disease
... Huntington's, Zamore couldn't see a way.
"I explained to him that you can't," Zamore said. The problem was that the disease gene and its healthy allele
are almost identical, and Zamore told Aronin that he wouldn't be able to distinguish between the two forms of Huntingtin . "Then, as he was leaving ...
Researchers identify 4 genetic hotspots associated with psoriasis
... psoriasis and has been found numerous times by many investigators. Most recently, the Elder group showed this association appears to be linked to an allele
of HLA-C called *0602, and the latest study confirms this, once again. Three new polymorphisms reported in the Nature Genetics studyIL-23A, ...
Fitness in a changing world
... laboratory mapping results, and the rapid loss of plates observed in nature, biologists hypothesized that selection would always be for the Eda low allele
An experimental test by Barrett et al. has shown surprisingly unexpected results in fitness of the fish. The fish's lifespan is ...
Research pushes back history of crop development 10,000 years
... Archaeobotany is also producing further evidence to undermine the quick development model. The tough rachis mutant is caused by a single recessive allele
(one gene on a pair or group of genes) , and this mutant is easily identifiable in the archaeological specimens as a jagged scar on the chaff of the ...
October 2008 Biology of Reproduction highlights
... the IAP (intracisternal A-particle) element that controls expression at the coat-color A vy (agouti viable yellow) allele; mice bearing this allele
exhibit coat-color differences reflective of the extent of methylation on the IAP element. Morgan et al. found highly significant differences in ...
Genetic variants of USF1 are associated with the increased risk for cardiovascular disease
... complex interactions between USF1 effects and the pathophysiological state of an individual.
To address the question if carriership of this risk allele
has a direct impact on the atherosclerotic lesions of the coronary arteries and abdominal aorta, Kristansson used two study samples of middle-aged ...
Cognitive, genetic clues identified in imaging study of alcohol addiction
... or methionine. The Val form of the gene is associated with lower dopamine levels, and Boettiger's study showed that people with two copies of the Val allele
(resulting in the lowest dopamine levels) had significantly higher frontal and parietal activity and chose now over later significantly more often. ...
Simple reason helps males evolve more quickly
... interactions and more straightforward male inheritance, especially since the males Y chromosome contains very few genes.
In females, a dominant allele
can hide the presence of a recessive allele, said Lauren McIntyre, an associate professor of molecular genetics and microbiology in UFs College of ...
Alcoholism, smoking and genetics among Plains American Indians
... a common COMT polymorphism, Val158Met. "The Met allele
results in a less efficient enzyme and therefore ... norepinephrine in the brain," she said. "The Met allele
has also been associated with increased anxiety ... studies of European men have shown that the Met allele
is associated with late onset alcoholism and ...
Researchers find gene mutation that causes infertility in male mice
... that blocks meiosis in its tracks, preventing sperm production. The mutant allele
(one version of the pair of genes we inherit from each parent) is ... mice. They then analyzed the DNA of the sterile males and identified the allele
that caused the infertility. While most studies on the genetics of ...
New research examines genetics of successful aging
As expected, the study identified an increased frequency of the APOE E2 allele
and a decreased frequency of the APOE E4 allele
among the elders compared to the group of young adults. These gene ...
Children's taste sensitivity and food choices influenced by taste gene
... either "like water" or "bitter or yucky."
Having a bitter-sensitive allele
(P) on the TAS2R38 receptor gene predicted sensitivity to the bitter taste ... for sweet-tasting beverages and foods. Children with a bitter-sensitive allele
(PP or AP) preferred higher concentrations of sucrose solutions than did ...
Discovery of the first resistance gene to rice yellow mottle virus
... of this resistance gene was performed by genetic transformation. For this, a line of resistant rice was modified by transgenically introducing the allele
for susceptibility of this gene. The descendents of transformed plants that manifested restored susceptibility always showed the presence of the ...
Mutant mouse provides insights into breast cancer
... rate of faulty DNA replications and genomic instability.
"It's insidious because there is no warning that one might have this cancer predisposing allele
[DNA codings at a given site] because the mice live normally," said Schimenti, who is also director of the Center for Vertebrate Genomics.
Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals
... admixture did indeed occur, then [it would] manifest in our data as an abundance of low-frequency derived alleles in Europeans where the derived allele
matches Neanderthal. No site in the data set appears to be of this type."
However, Pritchard said, "We do not exclude the possibility of modest ...