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Addiction in Biological News

Study suggests salt might be 'nature's antidepressant'

... substance -- almost like a drug. One sign of addiction is using a substance even when it's known to be ... foods bland. Another strong aspect of addiction is the development of intense cravings when drugs ... the same brain pathways as those related to drug addiction and abuse," Johnson said. ...

Addiction: Insights from Parkinson's disease

... vital insights into the neurological basis of addiction by investigating Parkinson's disease patients, ... and maintenance of addictive behaviours. addiction is a complex health and societal problem that can ... Brain imaging studies have shown that addiction severely alters brain areas critical to ...

Researchers find link between nicotine addiction and autism

... in the brain that has links to both nicotine addiction and autism. The finding has led to speculation that existing drugs used to curb nicotine addiction might serve as the basis for potential therapies ... Anand and colleagues were studying drug abuse and addiction when they discovered the neurexin-1 beta ...

Large-scale investment catapults CAMH's mental illness and addiction research forward

... The Centre for addiction and Mental Health (CAMH) is proud to announce a ... treatment and prevention of mental illness and addiction to the next level of excellence. This funding ... point in the history of mental illness and addiction research, thanks to the generosity, support and ...

Lab study shows methadone breaks resistance in untreatable forms of leukemia

... discovered that methadone, an agent used to break addiction to opioid drugs, has surprising killing power ... methadone can, itself, become addictive, that addiction is much easier to break compared to addiction to true opioids. "Addiction shouldn't be an ...

Cognitive, genetic clues identified in imaging study of alcohol addiction

... Journal of Neuroscience that took a novel tack in addiction imaging research. "Our data suggest there may ... who is senior author of the study. Most addiction imaging studies have focused on the brain ... is that her study provides more evidence that addiction is a disease, something even some of her peers do ...

Drug-proof zebrafish reveal secrets of addiction

... Biology , provides clues to the genetics that underlie susceptibility to addiction by describing the nad zebrafish mutant, which does not feel the rewarding ... are only partially understood. Because a major step in the development of addiction is the switch from drug use to drug abuse, we aimed to gain insight into ...

Cocaine: Perceived as a reward by the brain?

... the reward circuits in the brain but also associates the susceptibility to addiction with these mechanisms. The results of this study show that sniffing ... circuit that leads to addiction, or is it an inherent sensitivity to addiction that leads to the increased secretion of dopamine? This question is not ...

Cocaine: How addiction develops

... with new approaches in the medical treatment of drug addiction. addiction leaves detectable traces in the brain: In particular regions of the ... many years that drug-induced synaptic plasticity plays a crucial role in addiction development. However, this hypothesis has not yet been proven ...

If your first cigarette gave you a buzz and you now smoke, a gene may be to blame

... Research Laboratory. "If cigarette smoking is sustained, nicotine addiction can occur in a few days to a few months," he adds. "The finding of a ... "Understanding the genetics of complex disorders such as nicotine addiction will require much more research on key traits," he says. The team notes ...

Methadone even at therapeutic levels can kill

... taken at therapeutic levels primarily for relief of chronic pain or drug addiction withdrawal, a new study by Oregon Health & Science University researchers ... of methadone, a synthetic opiate, is increasing steadily not only for drug addiction but also among cancer patients for managing chronic pain largely because ...

New studies on schizophrenia, depression, trauma and autism highlight annual meeting

... in boys and girls. (Embargoed until 9:00 a.m. EST December 8) Nicotine addiction Might be Controlled by Influencing Pleasurable Response Mechanisms in ... help curb the pleasurable effects of nicotine and help people break their addiction to it. (Embargoed until 9:00 a.m. EST December 8) Stable Sleep Patterns ...

Club drugs inflict damage similar to traumatic brain injury

... Working with UF researchers Dr. Mark Gold, chief of the division of addiction medicine at UFs McKnight Brain Institute and one of the countrys leading experts on addiction medicine, and Kevin Wang, director of the UF Center for Neuroproteomics ...

Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring

... factors from diet and physical activity to stress and substance addiction in order to begin sorting out how these different factors affect a ... Memphis, Tenn. Wireless Skin Patch Sensors to Detect and Transmit addiction and Psychosocial Stress Data $429,000 Kenzie L. Preston, Ph.D., ...

NIH stimulus funding supports Emory biomedical scientists

... expect to advance research discoveries in areas ranging from heart disease, cancer and neurology to organ transplantation, pulmonary diseases, addiction and epilepsy. In addition to research grants, NIH provided funding for Emory scientists to hire eight high school students, 22 college students, ...

Discovery may provide new treatments for alcohol dependence

... Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have discovered a new brain mechanism involved in alcohol addiction involving the stomach hormone ghrelin. When ghrelin's actions in the brain are blocked, alcohol's effects on the reward system are reduced. It is an ...

MCG researcher among first to receive NIH stimulus funding

... been clinically identified yet, that would make a difference when deciding a treatment plan," Dr. NeSmith says. Some drugs used to treat cocaine addiction have adverse effects on the kidneys, so it's important to know if a patient suffers from asymptomatic renal disease. If that's the case, alternative ...

Skin color clue to nicotine dependence

... types of smoking behavior, dependence, and health outcomes that will be different from those in less pigmented populations," explained King. "And the addiction process may very well be longer and more severe." The team's findings appear in the June issue of the journal Pharmacology, Biochemistry and ...

Early isolation linked to enhanced response to cocaine

... NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health ...

Early isolation linked to enhanced response to cocaine

... NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health ...

To fight drug addiction, UB researchers target the brain with nanoparticles

... BUFFALO, N.Y. -- A precise, new nanotechnology treatment for drug addiction may be on the horizon as the result of research conducted at the University at Buffalo. Scientists in UB's Institute for Lasers, Photonics and ...

Nicotine activates more than just the brain's pleasure pathways

... complement what is known about the effects of nicotine in the dopamine pathway. This is the classic pleasure pathway in the brain, much studied by addiction experts. "Our study in no way contradicts prior findings about nicotine and dopamine," Oliveira-Maia said. "Our findings add to what is known and ...

Rethinking the genetic theory of inheritance

... Embargoed Until January 18, 2009 at 18:00 Greenwich Mean Time / 13:00 Eastern Standard Time (TORONTO): Scientists at the Centre for addiction and Mental Health (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called ...

Honeybees succumb to cocaine's allure

... out more about the drug's effects. He hopes to identify the neural pathways that it targets to find out more about the mechanisms involved in human addiction and to find out whether the drug has as devastating an effect on honey bee society as it does on human society. ...

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

... Institute at the Mount Sinai School of Medicine, in New York. The goal of Dr. Nestler's research is to better understand the molecular mechanisms of addiction and depression. He uses animal models to identify the ways in which drugs of abuse or stress change the brain to lead to addiction- or ...

Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue

... studied protein involved in inflammation, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, the effect of general anesthetics and addiction to alcohol, nicotine and cocaine. Moreover, the results apply to closely related receptors that bind serotonin and GABA, which are ...

American Chemical Society's Weekly PressPac -- Sept. 10, 2008

... ARTICLE #1 FOR IMMEDIATE RELEASE Potential new drug for cocaine addiction and overdose Journal of the American Chemical Society Chemists are reporting development of what they term the most powerful substance ever ...

Abuse of painkillers can predispose adolescents to lifelong addiction

... "Together, these results suggest that adolescents who abuse prescription pain killers may be tuning their brain to a lifelong battle with opiate addiction if they re-exposed themselves to the drug as adults," says Kreek. "The neurobiological changes seem to sensitize the brain to the drug's powerfully ...

'Erasing' drug-associated memories may stop drug addiction relapses

... help individuals resist relapse and maintain their abstinence." Dr Amy Milton, a co-author, said, "This is a new approach to the treatment of drug addiction that has great potential. Additionally, this might also be used to treat other neuropsychiatric disorders characterized by maladaptive memories, ...

Unlocking mystery of why dopamine freezes Parkinson's patients

... CHICAGO -- Parkinson's disease and drug addiction are polar opposite diseases, but both depend upon dopamine in the brain. Parkinson's patients don't have enough of it; drug addicts get too much of ...

Study finds connections between genetics, brain activity and preference

... of behaviors," says Hans Breiter, MD, senior and corresponding author of the study and principal investigator for the Phenotype Genotype Project in addiction and Mood Disorders, an interdisciplinary project involving the MGH Departments of Radiology, Psychiatry, and Neurology. "In the ongoing discussion ...

Humans' response to risk can be unnecessarily dangerous, finds Tel Aviv University study

... complex the risk, the more difficult to predict how people will react. Lotem cautions that in complicated decision-making scenarios such as gambling, addiction and excitement are new variables that come into play. It is also difficult to assess whether children exhibit similar risk-taking strategies as ...

N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets

... to developing more effective therapies for mood disorders and neurologic and psychiatric diseases, and to direct effective treatments for drug addiction to cocaine and amphetamines," says co-lead author Dr. Harel Weinstein, Chairman and Maxwell M. Upson Professor of Physiology and Biophysics, and ...

Pregnant mice block out unwelcome admirers to protect their pups

... of hormones. Dopamine is also found in humans, where it is mostly known for its role as the brain's 'reward chemical' that plays crucial roles in addiction and neurological disorders like Parkinson's disease, but it is also found in the human olfactory bulb. It is unknown if a process similar to the ...

Hunger hormone: Makes food more attractive

... and colleagues found that ghrelin worked on regions of the brain known to be involved with reward and motivation, the same regions implicated in drug addiction the amygdala, insula, the orbitofrontal cortex (OFC) and striatum. These areas work together to assign incentive value to objects in the world and ...

New gene discovered for new form of intellectual disability

... The Centre for addiction and Mental Health (CAMH) has discovered a new form of intellectual disability involving mental retardation (MR) along with the eye defect retinitis ...

Coral's addiction to 'junk food'

... Over two hundred million humans depend for their subsistence on the fact that coral has an addiction to junk food - and orders its partners, the symbiotic algae, to make it. This curious arrangement is one of Natures most delicate and complex ...

Epigenetic changes discovered in major psychosis

... to fully understanding major psychosis. Dr. Arturas Petronis, senior scientist in the Krembil Family Epigenetic Laboratory at the Centre for addiction and Mental Health (CAMH), and his team studied 12,000 locations on the genome using an epigenomic profiling technology developed at CAMH. ...

Are some men predisposed to pedophilia?

... October 22, 2007 (TORONTO) Height may point to a biological basis for pedophilia, according to new research released by the Centre for addiction and Mental Health (CAMH). The study found that pedophilic males were shorter on average than males without a sexual attraction to children. The ...

Tolerance to inhalants may be caused by changes in gene expression

... of an animal to future doses by epigenetically modifying a single gene. The research lays the groundwork for understanding mechanisms of inhalant addiction in humans, and it is hoped, developing methods of treatment and recovery. Because the effects of organic solvent inhalants and alcohol on animals are ...
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