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Acids in Biological News

Trans fats hinder multiple steps in blood flow regulation pathways

... oils in processed foods contain trans fatty acids that interfere with the regulation of blood flow. ... of double bonds in the essential fatty acids in the oil and "saturating" the "unsaturated" ... displace and cannot replace the essential fatty acids linoleic acid (omega-6) and linolenic acid ...

Omega fatty acid balance can alter immunity and gene expression

... have altered the consumption of omega-6 fatty acids (w6, found in meat and vegetable oils) compared with omega-3 fatty acids (w3, found in flax and fish oil). Many studies ... to as high as 10:1. Since these omega fatty acids can be converted into inflammatory molecules, ...

'Disordered' amino acids may really be there to provide wiggle room for signaling protein

... and an ezrin-binding motif, a sequence of amino acids that connects NHREF1 to cellular proteins such as ... for human proteins, over one third of the amino acids that make up NHERF1 were predicted to be ... disordered segments, approximately 100 amino acids long, which enable the protein to work. That is, ...

Eating fatty fish once a week reduces men's risk of heart failure

... adding to growing evidence that omega-3 fatty acids are of benefit to cardiac health. Led by ... demonstrated that fatty fish and omega-3 fatty acids help to combat risk factors for a range of ... who consumed 0.36 grams per day of omega-3 fatty acids showed a 33 percent reduced risk of heart ...

Quails get super fit by simply eating omega-3 diet

... have some of the highest levels of n-3 fatty acids (better known as omega-3 fatty acids) of any ... from the University of Ottawa, omega-3 fatty acids have some rather astonishing effects. In humans ... fit simply by eating a diet rich in omega-3 fatty acids on 27 March 2009 in The Journal of Experimental ...

Scripps scientists find structure of a protein that makes cancer cells resistant to chemotherapy

... inside. The cavity's interior is lined with amino acids that bind to various substances, holding them in ... that the mammalian P-gp has many more such amino acids and a greater variety of them, including aromatic amino acids that are known to bind many different substances ...

NASA researchers find clues to a secret of life

... life uses only left-handed versions of amino acids to build proteins." Glavin is lead author of a ... to make words, life uses 20 different amino acids in a huge variety of arrangements to build ... hands. Although life based on right-handed amino acids would presumably work fine, "you can't mix them," ...

Unfolding 'nature's origami'

... tip that balance." Proteins are made of amino acids arranged in a linear chain and the sequence of these amino acids is determined by the gene producing them. How these chains of amino acids are preprogrammed to fold into their correct ...

Relationships in rank and file

... the sequence of DNA components or amino acids with all sequences in the database in just a few ... each other in such a way that similar amino acids come to lie in the same columns. The sequence ... amino acids. Here, the similarity between amino acids is measured by how often they mutate into each ...

'Fishy' clue helps establish how proteins evolve

... rare amino acid and, by example, other amino acids made its way into the menu for protein ... in the genome. All of the 20 common amino acids are incorporated into proteins in this way. ... from modification of one of the standard 20 amino acids after it has become part of the protein. Many ...

Johns Hopkins scientists pull protein's tail to curtail cancer

... flexible tail contains a cluster of four amino acids the building blocks of proteins that regulate ... as PTEN. When chemically modified, these amino acids act to "glue" the tail back to the body of PTEN ... tail, or manipulating the cluster of four amino acids so that they cannot be modified, the researchers ...

A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart

... is associated with higher levels of omega-3 fatty acids in plasma and red blood cells. This is the major ... a 'trigger', boosting the amount of omega-3 fatty acids in our body. "Several studies have shown that ... men, had higher concentration of omega-3 fatty acids in plasma and red blood cells independently of ...

Study reveals surprising details of the evolution of protein translation

... of transfer RNA, a molecule that delivers amino acids to the protein-building machinery of the cell, ... carries instructions for the sequence of amino acids in a protein), while the other transfers a ... and each carries only one of the 20-plus amino acids found in proteins) so the researchers looked for ...

Eating fish may explain very low levels of heart disease in Japan

... quantities of fish loaded with omega-3 fatty acids may explain low levels of heart disease in Japan, ... Japan to compare serum levels of omega-3 fatty acids and atherosclerosis among Japanese, white ... and two times higher levels of omega-3 fatty acids than white Americans or Japanese Americans. ...

Bacteria reveal secret of adaptation at Evolution Canyon

... found significant differences in the fatty acids of several ecotypes that live on different slopes ... from the hot slopes had more heat-tolerant fatty acids and 'European' ecotypes from the cool slopes had more cold-tolerant fatty acids in their membranes." In most modern ...

Scientists suspect omega-3 fatty acids could slow acute wound healing

... remains a mystery. The omega-3 fatty acids found in fish oils are widely considered to ... the increased systemic presence of omega-3 fatty acids in the blood. "That finding was hard to ... the proteins." If the polyunsaturated fatty acids in the fish oils do indeed delay acute wound ...

Scientists learn how food affects the brain

... . Omega-3 fatty acids found in salmon, walnuts and kiwi fruit provide ... synapses, Gmez-Pinilla said. "Omega-3 fatty acids support synaptic plasticity and seem to ... on synapses," Gmez-Pinilla said. "Omega-3 fatty acids are essential for normal brain function. ...

Trans-fatty acids and insulin sensitivity

... Trans-fatty acids have been the topic of a lot of negative health ... incubating muscle cells with either trans-fatty acids or oleic acid (olive oil); as in the rats, there ... of the cells. So while trans-fatty acids are still relatively unhealthy, these findings do ...

Purple extremist thrives under inhospitable conditions

... conditions are a prerequisite for life. Strong acids or dissolved metallic salts in high ... Great Britain to identify an enzyme that requires acids and dissolved metals in order to function. The ... At that time the earth was very inhospitable; acids and metals in soluble form were everywhere. Peter ...

Researchers observe spontaneous 'ratcheting' of single ribosome molecules

... molecule that codes for the sequence of amino acids in the protein. Another molecule, transfer RNA ... ribosome. Transfer RNAs bring individual amino acids into the ribosome where they are assembled into ... ribosome, read the code and deliver their amino acids one by one to a growing protein chain. The ...

American Chemical Society’s Weekly PressPac -- May 7, 2008

... of proteins containing so-called unnatural amino acids (UAAs). Living things normally use the same basic set of 20 amino acids to make proteins. Scientists have made additional ... Efficient Incorporation of Unnatural Amino acids in Yeast DOWNLOAD FULL TEXT ARTICLE ...

Birth of an enzyme

... i.e., to determine the sequence of the 200 amino acids that make up the structure of the protein. This ... of ways to arrange 20 different types of amino acids into strings of 200. But in practice, only a ... are available as the sequence of amino acids determines the structure of the enzyme, which in ...

Meteorites a rich source for primordial soup

... have discovered concentrations of amino acids in two meteorites that are more than ten times ... in Meteoritics and Planetary Science.* Amino acids are organic molecules that form the backbone of ... of life. Scientists have determined that amino acids could also have formed in some environments on ...

Typical North American diet is deficient in omega-3 fatty acids

... and not much fish is deficient in omega-3 fatty acids and this may pose a risk to infant neurological development. Omega-3 fatty acids are unsaturated fats found in some fish such as ... Journal of Clinical Nutrition. Omega 3 fatty acids are important for the babys developing eyes and ...

ASU researcher may have discovered key to life before its origin on Earth

... that contain among a variety of compounds, amino acids that have identical counterparts in terrestrial ... ASU professor emeritus John Cronin analyzed amino acids from the Murchison meteorite (which landed in ... discovered a preponderance of left-handed amino acids over their right-handed form. The findings ...

Why the switch stays on

... incessantly. There are 20 existing amino acids that can be joined into chains that make up ... of amino acids. In the chain of 189 amino acids of which Ras is composed, the position in ... position 61 as a leucine or one of the few amino acids shown to cause cell transformation, one of the ...

Elsevier announces new journal partnership for 2008

... Prostaglandins, Leukotrienes & Essential Fatty acids (PLEFA) will become the Official Journal of the International Society for the Study of Fatty acids and Lipids (ISSFAL). 2008 also marks the ... together to better understand the role of fatty acids and their several important bioactive metabolites ...

Story ideas from the Journal of Lipid Research

... to chronic diarrhea. Liver-produced bile acids are intestinal detergents that break apart fats for easier absorption. Normally, most of the bile acids also reabsorb, but during certain conditions (e.g. infection or short bowel syndrome) excess bile acids enter the colon and impair water absorption, ...

Omega-3 fatty acids protect against Parkinson's, study says

... Quebec City, November 26, 2007Omega-3 fatty acids protect the brain against Parkinsons disease, ... protective effect of a diet rich in omega-3 fatty acids against Parkinsons. Parkinsons disease is ... type of omega-3had replaced the omega-6 fatty acids already present in the brains of the mice that ...

Rebuilding the evolutionary history of HIV-1 unravels a complex loop

... they are so diverse; up to 35% of the amino acids can differ between strains of HIV-1. Exposed to ... encoding the V3 loop to discover groups of amino acids that were biologically dependent on each other. These co-evolving amino acids formed ties across the V3 loop like rungs on a ...

American Chemical Society's Weekly PressPac -- Oct. 31, 2007

... long have known that flavonoids and phenolic acids have beneficial health effects in reducing the ... cells. The researchers studied how 15 phenolic acids and six flavonoids affected fat cells in ... RELEASE Effects of Flavonoids and Phenolic acids on the Inhibition of Adipogenesis in 3T3-L1 ...

St. Jude influenza survey uncovers key differences between bird flu and human flu

... virus proteins. The differences in these amino acids can be used as markers to track changes in H5N1 ... computationally surveying the sequence of amino acids in 10,671 proteins from avian influenza viruses ... acquiring the preferred human influenza amino acids in stages. Eventually, descendents of the ...

Mice run faster on high-grade oil

... on a diet high in polyunsaturated fatty acids. Polyunsaturated fatty acids are important dietary components which mammals cannot synthesize de novo. ... Combined, these two studies suggest that diets enriched in these fatty acids "could also affect the maximum (or burst) running speed of other ...

Scripps Research scientists observe human neurodegenerative disorder in fruit flies

... of molecules called transfer RNAs (tRNAs) to supply them with the amino acids they need to construct the proteins. The tRNA synthetases are needed to attach amino acids to the tRNAs. Sound complicated? It is. But the action of tRNA ...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

... structure that is determined by the energy balance between the amino acids that make them up. The group of Scripps Research Associate Professor ... light emitted from two fluorescent dyes that are attached to amino acids in the protein. The color of the measured light provides information about ...

An easy way to find a needle in a haystack by removing the haystack

... and reliably detect metabolites, such as sugars, fatty acids, amino acids and other organic substances from plant or animal tissue samples. One drop ... sample: they were able to determine a wide range of blood-specific organic acids in one drop of human blood, smaller than a micro liter. In medical ...

Omega-3 fatty acids appear to impact AMD progression

... BOSTON (June 18, 2009) - Omega-3 fatty acids found in fatty fish such as tuna and salmon may protect against ... "Data from the present study also shows the supplements and omega-3 fatty acids collaborate with low-dietary glycemic index (dGI) diets against ...

Fatty foods -- not empty stomach -- fire up hunger hormone

... or GOAT) for activation. Originally it was assumed that the fatty acids attached to ghrelin by GOAT were produced by the body during fasting. The new data by Tschp and his team suggests that the fatty acids needed for ghrelin activation actually come directly from ingested dietary ...

Genetic switch potential key to new class of antibiotics

... deoxyribonucleic acid (DNA) chains are copied into messenger ribonucleic acids (mRNAs). The mRNAs are then transported to ribosomes that pair them with transfer RNAs that contribute amino acids into a protein chain, thereby decoding the gene. In recent years, ...

HIV pays a price for invisibility

... But HIV is tricky. To get around HLA-B*5703, the virus mutates three amino acids that T cells need to recognize the infected cells, causing the killers to ... to a person without HLAB*5703, the virus changed its mutated amino acids back to their original sequence, most likely because the benefit of ...
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