Zygote
... or polyploid and have the same alleles at a
locus (position) on homologous chromosomes . Full art... Homo zygote . With respect to a given genetic
locus , a diploid individual carrying two identical alleles Hydrographic. Referring to the arrangement...
Wild-type
...e to a particular mutation ( wild-type at that
locus or site , denoted by a plus sign). Cis ... Full article >>> In second instar wild-type wing discs, wg is express ed distal ly in a wedge of anterior ventral cells (Couso et al. 1993; Williams et al. 1993; Ng et al. 1996) Win...
VNTR
...;> Variable-number tandem-repeat ( VNTR ) A
locus including a tandemly repeated sequence may exhi...c variation in the alleles available for that
locus . Full article >>> See also variable-number-of-tandem- repeats ( VNTR )
locus . Thi...
Transversion
...hat can be mapped to one specific site within a
locus . A small mutation that consists of the replacement ( transition or transversion ); addition; or deletion ( frameshift ) of one or a few bases . Full article >>> Since transition mutation s ( purine to purine or pyrimidi...
Trait
...s determined by a single allele at a particular
locus . dormant Having reduced metabolic and respiratory activity. Full article >>> A group of trait s, such as size and number of offspring , length of maturation, age at first reproduction , and the number of times reproduction occurs...
TATA box
...pping ] [Hershey-Chase experiment] T4 virus [rII
locus ] TACO (tryptophan-aspartate coat protein ) Taenia solium Taiga TAP = Trans porter associated with antigen processing Tapeworms Taste, in human s TATA box Tatum, E. L. Full article >>> Many eukaryotic promoter s, but by no me...
Synapse
... synapse (sin-aps) [Gk. synapsis , a union] The
locus where one neuron communicates with another neu... . Full article >>> synapse the
locus where one neuron communicates with another neuron in a neural pathway; a narrow gap between a...
Survival
...gmentation and decomposition Locus . See Genetic
locus ... Full article >>> nutrient -- Any element or simple compound necessary for the health and survival of an organ ism. This includes air and water, as well as food. Full article >>> In the evolution ary sense , s...
Strain
...#62;> This is achieved by superimposing the
locus of interest on the genetic background of another by first crossing two inbred lines followed by extensive (about 20 generations) backcross ing hybrid s to one parental line (the background strain ) while ... Full article >>> He o...
Sperm
...A genetically engineered microorganism. Gene . A
locus on a chromosome that encodes a specific protein or several related proteins . Full article >>> gametes Reproductive cells ( sperm or egg ) which are haploid . gangliosides Sphingo lipids containing complex oligosaccharide...
Single locus probe
...ives per marker by hybridization of 45 single
locus probe s. All 1,076 marker -positive BAC clones ...; Probe s made of these sequence s are single
locus probe s and yield patterns such as those at left when used to probe RFLP blots of DNA s of six ...
Sequence
...ce located on either side of a specific genetic
locus . Full article >>> nucleotide sequence s in nuclear RNA that are eliminated during the formation of m RNA ; also called intervening sequence s Source: Jenkins, John B. 1990. Human Genetics , 2nd Edition. New York: Harper &...
Segment
... Gene : the segment of DNA at a particular
locus on a particular chromosome that controls production of proteins and enzymes and influences the development of a specific trait . Full article >>> Using specialized DNA technology to produce multiple, exact copies of a single ...
Seed
...sequence s extending on either side of a specific
locus or gene . Full article >>> Often ...ds . Full article >>> In peas, the
locus for seed texture (smooth or wrinkled) and seed color (yellow or green) are on two different ch...
RFLP
...de sequence between alleles at a chromosomal
locus result in restriction fragment s of varying lengths detected by Southern ana lysis . Restriction map . See Mapping . Retrovirus . Full article >>> Gusella and his research team, who used RFLP s to identify a marker . Testing a l...
Restriction enzyme
...also variable-number-of-tandem- repeats ( VNTR )
locus . Full article >>> Labs (CEPRAP): Electrophoresis , Restriction Enzyme s , Bacteria l Transformation - Video/laser disc ... Full article >>> restriction endonuclease - aka restriction enzyme - bacteria l en...
Repressor
...revents transcription of a gene at some other
locus Source: Jenkins, John B. 1990. Human Genetics , 2nd Edition. New York: Harper & Row ... Full article >>> Repressor proteins are coded for by regulator genes. Repressor proteins then attach to a DNA segment known as ...
Repeats
...also variable-number-of-tandem- repeats ( VNTR )
locus . This site is dependent on visitors like you. If you think you can add more to this definition or see a correction that needs to be made, click on the EDIT button below and fix it. Full article >>> In mass production, each worker r...
Redox reaction
...inant DNA Recombination [in meiosis ] [ in rII
locus ] [in T-even bacteriophages ] [ nodule ] [ signal sequence (RSS)] Recommended dietary allowances (RDAs) (table) Reconsolidation, of memories Red blood cells Redox potential Redox reaction A ... Full article >>> The electron is "b...
Red blood cells
...article >>> Variation at a single
locus determines whether red blood cells are shaped normally or sickled. If a human has two alleles for sickle- cell , he/she develops anemia -- the shape of sickle- cells precludes them carrying normal levels of oxygen . Full article >>&...
Recombination frequency
...ual to a 1% chance that a marker at one genetic
locus will be separated from a marker at a second
locus due to crossing over in a single generation. Full article >>> Centimorgan (cM): ...
Random mating
... Fe value based on the number of alleles in the
locus of interest, neutrality expectations and random ...frequencies of genotype s in a population at a
locus are determined by random mating and allele frequency Herbivore . An organ ism that consumes ...
Quantitative trait
...62; In animal studies of quantitative trait
locus (QTL) mapping studies, two animals with extremes of the phenotype (like lowest and highest blood pressure) are mated to generate F1 and then F1 x F1 mating s ... Full article >>> Mayr. 1997. What is Biology . Harvard Universi...
Proteins
... Gene : the segment of DNA at a particular
locus on a particular chromosome that controls production of proteins and enzymes and influences the development of a specific trait . Full article >>> The process in which molecule s (such as proteins , DNA , or RNA fragments) ...
Protein
... Gene : the segment of DNA at a particular
locus on a particular chromosome that controls production of protein s and enzymes and influences the development of a specific trait . Full article >>> The detection of identified protein s by electron microscopy, which makes us...
Probe
...n genes or DNA fragments of interest. (See Multi
locus probe .) ... Full article >>> Probe : Single- strand ed DNA or RNA fragment of specific base sequence , labeled either radioactively (often incorporating 32P or 35S) or immunologically, that are used to detect the complement ...
Positional cloning
... its product. Usually involves linking the gene
locus of interest to one that has already been mapped. Full article >>>...
Polymorphisms
...que for detecting polymorphisms at a particular
locus . Following PCR amplification of a
locus , polymorphisms are detected by differences in restriction fragment sizes between individuals. R...
Polygenic inheritance
...polygenic trait is due to more than one gene
locus . It involves active and inactive alleles . Active alleles function additively. Full article >>> polygenic inheritance . Inheritance of trait s influenced by multiple alleles ; trait s show continuous variation between extre...
Polymorphism
...of an organ ism, with respect to a given genetic
locus , the alleles it carries ... Full article >>> Genetic polymorphism The existence of two or more genetically different class es within a population . Full article >>> Balanced polymorphism : The maintenance of tw...
Polygenic
...polygenic trait is due to more than one gene
locus . It involves active and inactive alleles . Active alleles function additively. Full article >>> polygenic inheritance . Inheritance of trait s influenced by multiple alleles ; trait s show continuous variation between ext...
Palindromic Sequence
...dromic sequence . Palindromic sequence . A DNA
locus whose 5'-to-3' sequence is identical on each DNA strand . The sequence is the same when one strand is read left to right and the other strand is read right to left. Full article >>> The terminator sequence is usually a ...
Orthology
...ology Describes the evolution ary origin of a
locus . Loci in two species are said to be orthologous when they have arisen from the same
locus of their common ancestor. For example, gene A in species 1 and 2 are orthologous. Full article...
Neurotransmitter
...erentiation . Full article >>> the
locus where one neuron communicates with another neuron in a neural pathway; a narrow gap between a synaptic terminal of an axon and a signal-receiving portion ( dendrite or cell body ) of another neuron or effector cell . Neurotransmitter s...
Neural
...ado-Joseph disease. The protein encoded by the
locus affected by the fragile X syndrome, FMRP, binds to G-quartet structures on a subset of m RNA s, including those important in neural ... Full article >>> In many species of fish, amphibians, crustacea ns and reptiles, melanosomes ...
Natural selection
...ct of such interactions rather than on individual
locus . The correlated variation and adaptation present in two mutually dependent organ isms. Coalescence ... Full article >>> A particular aspect in the life cycle of an organ ism upon which natural selection acts. A B C D E F G H I...
Mutation
...the rate at which mutation s occur at a specific
locus ; usually express ed as mutation s per gamete per
locus per generation Source: Jenkins, John B. 1990. Human Genetics , 2nd Edition. New York: Harper &am...
Multiple alleles
...orms of allelic series that all map to a specific
locus Source: Jenkins, John B. 1990. Human Genetics ...e discussed two possible alleles for any gene
locus . For example, at the flower color
locus , there is either the red or the white allele (A or a)...
Monohybrid cross
...e gene is segregating or segregation at one
locus is being monitored. mono hybrid dominant / recessive cross ... Full article >>> monohybrid cross A breed ing experiment that uses parental varieties differing in a single character . monomer ... Full article >>> ...
Migration
...on , mutation , or migration . For a bi-allelic
locus where the gene frequencies are p and q: p2+2pq+q2 = 1 ( Online HWE Ana lysis ; ... Full article >>> PULSED-FIELD GEL ELECTROPHORESIS ( PFGE ) - Separation of large (>50 kb) pieces of DNA , including complete chromosomes an...
Mendel
...nship ... Full article >>> Genetic
locus . A location on a chromosome (possibly of a diploid organ ism with variants that segregate according to the rules of Mendel ian heredity ) Genetic polymorphism . Presence of several genetically controlled variants in a population ... Full ...
Mapping
...62; In animal studies of quantitative trait
locus (QTL) mapping studies, two animals with extremes of the phenotype (like lowest and highest blood pressure) are mated to generate F1 and then F1 x F1 mating s ... Full article >>> A system that allows automatic location of info...
Marker
element (
locus , allele , DNA sequence or chromosome feature) which can be readily detected by phenotype , cytological or molecular techniques, and used to follow a chromosome or chromosomal segment during genetic ana lysis . See centromere marker ; .....
Locus
... >>> Locus may refer to: The word
locus (plural loci ) is Latin for "place": In biology and evolution ary computation, a
locus is the position of a gene (or other significant sequence ) on a chromosome . Full article >...
Loci
... that maps to 8q. Full article >>>
locus pl. loci (loh-kus) [L. place] A particular plac...pose that there are 3 loci with 2 alleles per
locus (A, a, B, b, C, c). Full article >>>
locus (pl. loci ) a particular place along t...
Localize
...alize : Determination of the origin al position (
locus ) of a gene or other marker on a chromosome . Full article >>> A localize d extension of the body surface of many aquatic animals , specialized for gas exchange. gland [L. glans, glandis, acorn] ... Full article >>>...
Lobule
...ered in Lab 15 Rat Muscular and Digestive Systems
locus (pl. loci ) a particular place along the length of a certain chromosome where a given gene is located. Full article >>> In another study by Rikinari Hanayama and colleagues[11], milk fat g lobule epidermal growth factor 8 (MFG-E...
Linkage disequilibrium
... of only one of the two homologous alleles at a
locus in the case of heterozygosity . Full article >>> Whether a selective sweep has occurred or not can be investigated by measuring linkage disequilibrium , i.e., whether a given haplotype is overrepresented in the population . Full...
Linkage
... article >>> Linkage In peas, the
locus for seed texture (smooth or wrinkled) and seed... of only one of the two homologous alleles at a
locus in the case of heterozygosity . Full article >>> phosphodiester linkage - covalen...
Ligase
...more alternate forms ( alleles ) of a chromosomal
locus that differ in nucleotide sequence or have variable numbers of repeated nucleotide units. Full article >>> The re action is catalysed by the enzyme DNA ligase . Lysogen Bacteria l cell or strain which carries a copy o...
Kilobase
...isms to study gene function. See also: gene ,
locus , model organ isms Updated 26-Aug-06 ... Full article >>> Kilobase (Kb or Kbp) 1000 nucleotide s of DNA or RNA . Kinase An enzyme that trans fers phosphate from ATP to another molecule . Full article >>> ...
Intergenic
...e most common mechanism, especially for the HLA-B
locus , in the generation of new MHC alleles . Less common are conversion s between alleles of different MHC loci ( intergenic ... Full article >>>...
Imprinting
...nting Phenomenon in which an allele at a given
locus is altered or inactivated depending on whether it is inherited from the mother or father. Implies a functional difference in genes inherited from the 2 parents. Related Terms: Allele ... Full article >>> Imprinting If newly-hatche...
Hypostatic
...e relationship between alleles at a particular
locus . See a recent ... Full article >>> ...ence suppresses the effect of a gene at another
locus . Epistatic genes are sometimes called inhibiting genes because of their effect on other genes whi...
Homozygous
...ed by both alleles being the same at a specific
locus Source: Jenkins, John B. 1990. Human Genetics ...taining identical alleles for a given gene or
locus . Full article >>> A homozygous dominant genotype occurs when a particular loc...
Homozygote
... or polyploid and have the same alleles at a
locus (position) on homologous chromosomes . Full art...; Homozygote . With respect to a given genetic
locus , a diploid individual carrying two identical alleles Hydrographic. Referring to the arrangement...
Homologous chromosomes
...mologues may have different alleles at the same
locus ; one member of each pair comes from each parent. Full article >>> Homologous chromosomes . Chromosomes that have the same linear arrangement of genes--a pair of matching chromosomes in a diploid organ ism. See Chromosomes . ...
Homologous chromosome
...mologues may have different alleles at the same
locus ; one member of each pair comes from each parent. Full article >>> Homologous chromosome s . Chromosomes that have the same linear arrangement of genes--a pair of matching chromosomes in a diploid organ ism. See Chromosomes ....
Heterozygous
...rtaining to two different alleles at a specific
locus in a diploid organ ism Source: Jenkins, John B...aining dissimilar alleles for a given gene or
locus . Full article >>> A heterozygous carrier of red-green colorblindness has some co...
Heterozygote
... or polyploid and have different alleles at a
locus (position) on homologous chromosomes . Full art... Heterozygote . With respect to a given genetic
locus , a diploid individual carrying two different alleles ... Full article >>> Heter...