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VNTR

... set. Repetitive DNA sequence s may be closely linked (eg satellite DNA or VNTR loci ) or dispersed throughout the genome or parts of the genome (eg alu family ). Full article >>> VNTR Variable number tandem repeat. A type of DNA sequence found in eukaryotic genome s, in wh...

Uracil

...A DNA segment composed of repeated sequence s linked end to end. Conjugation . Full article >>> Base sequence -- a partnership of organ ic bases found in DNA and RNA ; adenine forms a base pair with thymine (or uracil ) and guanine with cytosine in a double- strand ed...

Unlinked

... unlinked . In particular, sex-linked genes are linked to one another. Full article >>> Mendel 's second law; unlinked of distantly linked segregating gene pairs behave independently Source: Jenkins, John B. 1990. Human Genetics , 2...

Tympanic membrane

... trans mitted across the middle ear by three tiny, linked bones, the ossicles: ... Full article >>>...

Transduction

...ction Homologous recombination of two closely linked genes or two mutation s within the same gene and brought into a cell on the same fragment of trans ducing DNA . Full article >>> Signal transduction . The biochemical events that conduct the signal of a hormone or growth ...

Topoisomerase

...;>> The task of unknotting topologically linked strand s of DNA falls to enzymes known as topoisomerase s. Some of these enzymes unknot circular DNA by cleaving two strand s so that another double- strand ed segment can pass through. Full article >>> The cohesion must b...

Thymine

...s-- adenine , thymine , cytosine , and guanine linked via intervening units of phosphate and the pentose sugar deoxyribose . Full article >>> that the amount of adenine , A, tends to be equal to that of thymine , T). Full article >>> important organ ic compound s ( bas...

Theory

...heritance the established theory that genes are linked to chromosomes and that chromosomes are the c...ome s. Now scientists believe transposon s may be linked to some genetic disorders such as hemophilia, leukemia, and breast cancer . Full article >>...

Telomere

...62; Genomic DNA in fragments of 200-500 kb are linked to sequence s which allow them to propagate in yeast as a mini- chromosome (including telomere s, a centromere and an ARS - an autonomous replication sequence ). Full article >>> Telomere . The end of a chromosome . Template...

Synteny

... on the same chromosome ; they may or may not be linked closely. Full article >>> Synteny Genes which occur in the same order on the chromosome of different species . Full article >>> A group of gene loci known to be linked; a chromosome . There are as many link...

Segregating

...; Mendel 's second law; unlinked of distantly linked segregating gene pairs behave independently Source: Jenkins, John B. 1990. Human Genetics , 2nd Edition. New York: Harper & Row ... Full article >>> Genetic load caused when a population is segregating less fit homozy...

Segment

...A DNA segment composed of repeated sequence s linked end to end. Conjugation . The joining of two bacteria cells when genetic material is trans ferred from one bacterium to another. Constitutive promoter . Full article >>> Deletion -- the loss of a segment of the genetic ma...

RNase

...hodiester bond remaining between the fragments is linked together by DNA ligase . Full article >>> cytoplasm (in eukaryotes m RNA is "processed" before being exported), where it is bound to ribosomes and trans lated into protein . After a certain amount of time the message degrad...

RNA

...tosine , and uracil , whose ribose components are linked by phosphodiester bond s. Full article >>...linear or branched polymer of monosaccharide units linked by glycosidic bonds. polysome (poly ribosome ) A complex of an m RNA molecule and many ribosom...

Ribozyme

... RNA ( ribonucleic acid ) Many ribonucleotides linked by successive 3',5'- phosphodiester bond s. Full article >>>...

Ribosomes

...linear or branched polymer of monosaccharide units linked by glycosidic bonds. polysome (poly ribosome ) A complex of an m RNA molecule and many ribosomes . Full article >>> Ribosomes are multimolecular aggregates containing RNA s and proteins . They can be separated into two subuni...

RFLP

... ; a technique using small bits of DNA fragments linked to various diseases. rhodopsin : a light-sensitive pigment of the eye that functions in the detection of light. ribonucleic acid : see RNA . Full article >>> RFLP is one of the origin al applications of DNA ana lysis to fore...

Retina

... ; a technique using small bits of DNA fragments linked to various diseases. Full article >>> Retina l consists of a system of alternating single and double bonds. In the dark, the hydrogen atoms attached to the #11 and #12 carbon atoms of retina l ( red arrows ) point in the same directi...

Restriction fragment

... ; a technique using small bits of DNA fragments linked to various diseases. rhodopsin : a light-sensitive pigment of the eye that functions in the detection of light. ribonucleic acid : see RNA . Full article >>> DNA insert and vector molecule s are digested with two different ...

Repulsion

... the condition (phase) of a heterozygote for two linked character -differences in which the two dominant factors were derived one from each parent of the individual, ... Full article >>> The tertiary structure is controlled by bonding (or in some cases repulsion ) between R-groups. Ma...

Repetitive DNA

... set. Repetitive DNA sequence s may be closely linked (eg satellite DNA or VNTR loci ) or dispersed throughout the genome or parts of the genome (eg alu family ). Full article >>> repetitive DNA A stretch of DNA consisting of multiple repeats of a motif . See also satelli...

Regulatory region

...he human gene for the V1a receptor have been linked to autism. Oxytocin Oxytocin is a peptide of 9 amino acids . It acts on certain smooth muscle s: ... Full article >>> Genetic constructs that include regulatory region s targeting gene expression to specific tissue s are necess...

Recombination

...process by which progeny derive a combination of linked genes different from that of either parent. In hig.... Full article >>> A set of closely linked genetic marker s present on one chromosome which tend to be inherited together (not easily separa...

Recombinant DNA

... series of techniques in which DNA fragments are linked to self-replicating forms of DNA to create recombinant DNA molecule s. These molecule s in turn are replicated in a host cell to create clones of the insert ed segment s. Full article >>> Recombinant DNA refers to DNA ...

Recombinant

... series of techniques in which DNA fragments are linked to self-replicating forms of DNA to create recombinant DNA molecule s. These molecule s in turn are replicated in a host cell to create clones of the insert ed segment s. Full article >>> Recombinant DNA refers to DN...

Proximal

... on the same chromosome ; they may or may not be linked closely. For example 2 gene loci that map to t...g arm of chromosome 1 respectively would not be linked but would ... Full article >>> First, a proximal explanation -- how does it work? A...

Proteins

...olism ) lacked certain enzymes . This observation linked proteins ( enzymes ) to genetic trait s. Full article >>> Proteins can also serve as molecular marker s through their enzymatic activities. The mouse MHC region contains the H2 major histocompatibility loci . The human m...

Protein

...olism ) lacked certain enzymes . This observation linked protein s ( enzymes ) to genetic trait s. Full article >>> Protein associated with DNA in chromosomes in the nucleus of the cell . Related Terms: Protein ... Full article >>> Protein Synthesis DNA , RN...

Probe

...robe . Full article >>> The closest linked marker (e.g., EST or a known gene ) to the gene is used to probe a genomic library . A restriction fragment isolated from the end of the positive clones is used to re probe the genomic library for overlapping clones . Full article &#...

Polysome

...linear or branched polymer of monosaccharide units linked by glycosidic bonds. polysome (poly ribosome ) A complex of an m RNA molecule and many ribosomes . Full article >>> Often many ribosomes will read the same message , a structure known as a polysome forms. In this way a cell...

Polysaccharides

...pound composed of a purine or pydimidine base linked to either a ribose or deoxyribose sugar. DNA and RNA are not polymers of nucleoside s. Full article >>> peptidoglycan A major component of bacteria l cell wall s consisting of parallel hetero polysaccharides cross-linked by s...

Polypeptide

...e polypeptide molecule s. The amino acids are linked covalently by peptide bond s. The image shows how three amino acids linked by peptide bond s into a tri peptide . Full article >>> polypeptide a molecule c...

Polyp

... polyp eptide molecule s. The amino acids are linked covalently by peptide bond s. The image shows how three amino acids linked by peptide bond s into a tri peptide . Full article >>> polyp loid y the condition...

Polymorphism

... ; a technique using small bits of DNA fragments linked to various diseases. rhodopsin : a light-sensitive pigment of the eye that functions in the detection of light. ribonucleic acid : see RNA . Full article >>> restriction fragment length polymorphism ( RFLP ) A heritable differ...

Polymerase

... A polymer composed of multiple amino acid units linked by peptide bond s. Full article >>> polymerase chain re action ( PCR ). A technique for preparing large quantities of DNA from tiny samples, making it easy to clone a specific gene as long as part of the sequence of the ...

Polar body

... whose molecule consists of many repeated units linked together. Full article >>> During the first meiotic division , a large secondary oocyte and a small polar body are produced. The secondary oocyte will divide to produce an egg and a polar body . The first polar body may div...

Pleiotropy

...le, sometimes two or more trait s are genetically linked through mechanisms such as pleiotropy (single gene that affects multiple trait s) and linkage disequilibrium (non-random association of two genes). Full article >>> Pleiotropy -- the phenomenon of variable phenotype s for a n...

Phospholipid

...embranes . Generally composed of two fatty acids linked through glycerol phosphate to one of a variety o...lipid molecule s in which a phos- phate group is linked to glycerol and two fatty acyl groups. A chief component of biological membranes . (See Inositol p...

Phosphodiester Bond

..., adenine , thymine , and cytosine , covalently linked through phosphodiester bond s. Full article >..., Adenine , Thymine , and Cytosine , covalently linked through phosphodiester bond s. Full article >>> Phospholipid s are also esters. N...

Peptides

...e polypeptide molecule s. The amino acids are linked covalently by peptide bond s. The image shows how three amino acids linked by peptide bond s into a tri peptide . Full article >>> Over the last few years, it ...

Peptide Bond

... A polymer composed of multiple amino acid units linked by peptide bond s. Polyploid . A multiple of the...everal hundred molecule s known as amino acids , linked by so-called peptide bond s. Full article >>> The oxygen or nitrogen atoms of the ...

Peptide

... A polymer composed of multiple amino acid units linked by peptide bond s. Polyploid . A multiple of the haploid chromosome number that results from chromosome replication without nuclear division . Full article >>> A poly peptide secreted by bacteria which inhibit or prev...

PCR

...IDE - A chain formed by two or more amino acids linked through peptide bond s: di peptide = two amino acids , oligo peptide = small number of amino acids , etc. Full article >>> PCR : see Polymerase Chain Re action . Phagemid : A type of plasmid which carries within its sequenc...

Oxygen

... (such as oxygen ) and a hydrogen atom which is linked covalently to another electronegative atom ; hydrogen bond ing is what makes water stick to itself. Deoxyribonucleic acid ( DNA ) ... Full article >>> The dis order is caused by a single base pair change in one of the genes that...

Overlapping clones

... genetic map depicting the relative order of a linked ( contig uous) library of small overlapping clones representing a complete chromosomal segment . Full article >>> Chromosome walking . Working from a flanking DNA marker , overlapping clones are successively identified that ...

Organ

...lly all organ ic molecule s contain carbon atoms linked together ... Full article >>> Plant organ s can be divided into vegetal and reproductive. Vegetal plant organ s are root, stem and leaf , while reproductive are flower , seed and fruit. [edit] Organ systems ... Full arti...

Operator

...ity of the structural gene s of an operon it is linked to, by interacting with a specific repressor or ...ds to regulate the activity of one or more closely linked structural gene s. Full article >>> operator A gene responsible for the activati...

Nucleotide

...ytosine in RNA ). Thousands of nucleotide s are linked to form a DNA or RNA molecule . Full article >>> Nucleotide sequence s, usually noncoding, that are present in many copies in a eukaryotic genome . The repeated units may be short and arranged tandemly (in series) or long an...

Nucleoside

... are nucleoside phosphates. A nitrogenous base linked to a sugar molecule . Related Terms: Nucleotide ...pound composed of a purine or pydimidine base linked to either a ribose or deoxyribose sugar. DNA and RNA are not polymers of nucleoside s. Full ...

Nuclein

...DNA and RNA , consisting of a nitrogenous base linked to a five carbon sugar. Full article >>>...

Nuclear membrane

...ng of a purine or pyrimidine base covalently linked to a pentose, but lacking a phosphate. Full article >>>...

Molecular biology

... deoxyribose in DNA ; ribose in RNA ) which is linked to a purine ( adenine or guanine ) or a pyrimidine ( thymine ( DNA ), cytidine or uridine ( RNA )). Full article >>> Among the resources at Cell and Molecular Biology Online are some pictures and movies. Or you could try C...

Membranes

...embranes . Generally composed of two fatty acids linked through glycerol phosphate to one of a variety of polar groups. Full article >>> meninges [L. meninx - membrane]. Membranes surrounding brain and spinal cord that have a protective function. Full article >>> [Gr. h...

Marfan syndrome

...s an autosomal dominant dis order that has been linked to the FBN1 gene on chromosome 15. FBN1 codes ...s an autosomal dominant dis order that has been linked to the FBN1 gene on chromosome 15. FBN1 encodes a protein called fibrillin, which is essential...

Marker

...ne ) from its known closest marker s. The closest linked marker (e.g., EST or a known gene ) to the gen.... Full article >>> A set of closely linked genetic marker s present on one chromosome which tend to be inherited together (not easily sepa...

Lysis

... - re action in which water breaks the covalently linked compound A-B hydrophilic - water "loving," hydrophilic molecule are soluble in water. hydrophobic - water "fearing," hydrophobic molecule s are quite insoluble in water ... Full article >>> glyco lysis : the sub division of ce...

Locus

...he fitter allele sweeps to fixation. Sequence s linked to the selected allele also increase in frequency due to hitchhiking. Full article >>> X-inactivation requires a locus on the X, called the X-inactivation center. At this locus , inactivation occurs in response to a developmental ...

Lipid

...nd consisting mainly of carbon and hydrogen atoms linked by nonpolar covalent bonds. Full article >...lipid molecule s in which a phos- phate group is linked to glycerol and two fatty acyl groups. A chief component of biological membranes . (See Inositol p...

Linkage equilibrium

...i to linkage equilibrium . But, the more closely linked two alleles are, the longer the hitchhiking will last. Full article >>>...

Linkage group

...ll article >>> linkage group Genes linked to the same chromosome that tend to be inherited...on the same chromosome to be inherited together. linked gene Gene located on the same chromosome as another gene . Full article >>> As...
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