enhancer

Upstream

...2;> Anything further upstream (but not an enhancer or other regulatory region whose influence is p... of a gene . They may be tissue -specific. The enhancer effect is mediated through sequence -specific DNA -binding proteins (see also silencer ). Ful...

Transgenic

...some which is used to identify tissue -specific enhancer s in the genome . Full article >>> A transgenic animal simply has a trangene of interest within its genomic makeup. A clone d animal is developed through nuclear trans fer, and typically has a common genetic profile with anoth...

Transcription factor

...ein that binds DNA at a specific promoter or enhancer region or site , where it regulates transcripti...lates the level of transcription ) by binding to enhancer elements in DNA and interacting with RNA polymerase at the promoter . Full article >...

Transcription

...lates the level of transcription ) by binding to enhancer elements in DNA and interacting with RNA polymerase at the ... Full article >>> transcription / translation control sequence s. That artificial construct (the " expression clone ") will produce a pseudo-mammalian protein if...

Transcript

...tes the level of transcript ion ) by binding to enhancer elements in DNA and interacting with RNA polymerase at the ... Full article >>> transcript ion / translation control sequence s. That artificial construct (the " expression clone ") will produce a pseudo-mammalian protein ...

Trans-

... Full article >>> In genetics , an enhancer is a short region of DNA which can be bound with proteins (namely, the trans- acting factors, much like a set of transcription factor s) to enhance transcription levels of genes (hence the name) in a gene -cluster. Full article >>&...

Template

...lates the level of transcription ) by binding to enhancer elements in DNA and interacting with RNA polymerase at the ... Full article >>> The synthesis of RNA using a DNA template . The process whereby RNA is synthesized from a DNA template . Full article >>> ...

TATA box

...on al complex. Full article >>> an enhancer , a TATA box ) and thereby, directly or indirectly, affects the initiation of transcription . Eukaryotic proteins that aid RNA polymerase to recognize promoter s. Analogous to prokaryotic sigma factor s. Full article >>> Histo...

Structural gene

... ed into host DNA molecule s promoter and enhancer sequence s to enable the gene to be express ed by host cells 2. Trans form ES cells in culture ... Full article >>> A set of adjacent structural gene s in bacteria whose m RNA is synthesized in one piece, together wit...

Skeletal muscle

...es character istic of skeletal muscle specific enhancer s and promoter s. Being able to determine the time and place of gene expression would be a useful step toward understanding its function. Full article >>> A type of receptor for the neurotransmitter acetylcholine, found on skel...

Sigma Factor

...> binds to a cis-regulatory element (eg. an enhancer , a TATA box ) and thereby, directly or indirectly, affects the initiation of transcription . Eukaryotic proteins that aid RNA polymerase to recognize promoter s. Analogous to prokaryotic sigma factor s. Full article >>>...

Sequence

...IOLOGY Paper On? Full article >>> enhancer - DNA sequence in a gene that influences the gene 's expression by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase ); ... Ful...

Repressor

...dentity and nature of cis-regulatory elements ( enhancer s and repressor s) at a ... Full article >>> The regulator gene codes for a repressor protein that binds to the operator , obstructing the promoter (thus, transcription ) of the structural gene s. The regulator does not hav...

Regulatory sequence

...in regulatory sequence s — promoter s and enhancer s — of their structural gene s. Full article >>> Enhancer A cis- actin g regulatory sequence that can increase transcription from an adjacent promoter . Full article >>> homeobox A highly conserved 180- b...

Regulatory region

... work in concert with other regulatory region s ( enhancer s, silencers, boundary elements /insulators) to direct the level of transcription of a given gene . Promoter sequence s Prokaryotic promoter s ... Full article >>> Site -directed mutagenesis is a sophisticated technique tha...

Promoter

... of a gene . They may be tissue -specific. The enhancer effect is mediated through sequence -specific DNA -binding proteins (see also silencer ... Full article >>> Because the transcription starts from a specific base -pair sequence (a promoter ) and stops at another (a termina...

Minerals

... Essential amino acids Nootropics (cognitive enhancer s) Dietary supplement Illnesses related to poor nutrition Pharmacology Vitamin poisoning (overdose) ... Full article >>> strategic minerals Materials a country cannot produce itself but that it uses for essential materials or ...

Kilobase

...increases transcription of a region even if the enhancer is distant from the region being trans cribed. Full article >>> 7 megabase s (1,700,000 bases ), while the mature (processed) neurexin m RNA s are under 10 kilobase s (10,000 bases ), with as many as 24 exons and thousands of p...

Gene regulatory network

...een genomic DNA fragments for tissue specific enhancer activities in Ciona intestinalis. Full article >>> So what that means is the gene regulatory network for developing the brain has changed in just the six million years of divergence between those two species quite markedly. Full ...

Gene expression

...sion can be caused by the juxtaposition of novel enhancer elements to a gene during genetic manipulatio...rmation to MAT is governed by a recombination al enhancer . Full article >>> A technique to monitor gene expression in thousands of genes. Th...

Expression

...sion can be caused by the juxtaposition of novel enhancer elements to a gene during genetic manipulatio...fluorescent dyes. Full article >>> enhancer - DNA sequence in a gene that influences the gene 's expression by increasing or decreasing ...

Express

...in chromosomes . Full article >>> enhancer - DNA sequence in a gene that influences the gene 's express ion by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase ); ... Ful...

Enhancer

...some which is used to identify tissue -specific enhancer s in the genome . Full article >>> Enhancer In genetics , an enhancer is a short region of DNA which can be bound with proteins (namely, the trans- acting factors, ...

Ectopic

...sion can be caused by the juxtaposition of novel enhancer elements to a gene during genetic manipulation of transgenic organ isms. Full article >>> Ectopic Occurring in an abnormal position or in an unusual manner or form, e.g. ectopic recombination . Related Terms: Recombinatio...

DNA sequence

... phage , results. Full article >>> enhancer - DNA sequence in a gene that influences the gene 's expression by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase ); ... Full ...

Actin

...e. Full article >>> Enhancer : An enhancer is a cis- actin g nucleotide sequence to which transcription factor (s) bind, and which increases the transcription of a gene . Full article >>> Vitamin . Chemical substances required in trace concentrations actin g as a cof...